Page last updated: 2024-08-21

indazoles and Respiratory Syncytial Virus Infections

indazoles has been researched along with Respiratory Syncytial Virus Infections in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	8 (88.89)	24.3611
2020's	1 (11.11)	2.80

Authors

Authors	Studies
Anderson, F; Chien, JW; Cihlar, T; DeVincenzo, J; Jordan, R; Lewis, SA; Miller, M; Perron, M; Perry, J; Porter, DP; Stray, K	1
Chen, D; Feng, S; Gao, L; Li, C; Shen, HC; Yun, H; Zheng, X	1
Chien, JW; DeVincenzo, JP; Farrell, E; Harrison, L; Jordan, R; Lambkin-Williams, R; Lewis, SA; Li, X; Lin, SL; Mackman, RL; McBride, S; O'Riordan, T; Ramanathan, S; Scaglioni-Weinlich, C; Toback, SL; Whitley, RJ; Xin, Y	1
Wright, PF	1
Babaoglu, K; Boojamra, C; Carey, A; Cihlar, T; Desai, M; Eisenberg, E; Gilbert, BE; Hayes, J; Hui, H; Iwata, Q; Jordan, R; Kinkade, A; Lee, G; Mackman, RL; Parrish, JP; Perron, M; Piedra, PA; Samuel, D; Sangi, M; Saunders, O; Siegel, D; Sperandio, D; Stray, K; Strickley, R; Theodore, D; Yang, H; Zhang, L	1
De Clercq, E	1
Anderson, ML; Behrens, NE; Carey, A; Chien, JW; Cihlar, T; Eisenberg, EJ; Gershwin, LJ; Jordan, R; Lewis, SA; Mackman, RL; McEligot, HA; Perron, M; Shao, M; Strickley, RG	1
Brendza, KM; Hung, M; Jordan, R; Liu, X; Mackman, R; Niedziela-Majka, A; Perron, M; Sakowicz, R; Samuel, D; Sperandio, D; Wong, JS; Xing, W	1
Cihlar, T; Eisenberg, E; Gilbert, BE; Jordan, R; Kinkade, A; Lee, G; Mackman, R; Perron, M; Piedra, PA; Sangi, M; Stray, K; Theodore, D; Toms, GL	1

Reviews

1 review(s) available for indazoles and Respiratory Syncytial Virus Infections

Article	Year
Chemotherapy of respiratory syncytial virus infections: the final breakthrough. International journal of antimicrobial agents, 2015, Volume: 45, Issue:3 Topics: Administration, Inhalation; Antiviral Agents; Humans; Indazoles; Pyrazoles; Respiratory Syncytial Virus Infections; Ribavirin; Sulfonamides; Treatment Outcome	2015

Trials

4 trial(s) available for indazoles and Respiratory Syncytial Virus Infections

Article	Year
Drug Resistance Assessment Following Administration of Respiratory Syncytial Virus (RSV) Fusion Inhibitor Presatovir to Participants Experimentally Infected With RSV. The Journal of infectious diseases, 2020, 10-01, Volume: 222, Issue:9 Topics: Adolescent; Adult; Amino Acid Substitution; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance, Viral; Humans; Indazoles; Middle Aged; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Sulfonamides; Viral Fusion Protein Inhibitors; Viral Load; Young Adult	2020
Oral GS-5806 activity in a respiratory syncytial virus challenge study. The New England journal of medicine, 2014, Aug-21, Volume: 371, Issue:8 Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Area Under Curve; Double-Blind Method; Female; Humans; Indazoles; Male; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Severity of Illness Index; Sulfonamides; Viral Load; Young Adult	2014
Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study. Journal of medicinal chemistry, 2015, Feb-26, Volume: 58, Issue:4 Topics: Administration, Oral; Animals; Antiviral Agents; Dogs; Dose-Response Relationship, Drug; Drug Discovery; Humans; Indazoles; Macaca fascicularis; Microbial Sensitivity Tests; Molecular Structure; Pyrazoles; Rats; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Structure-Activity Relationship; Sulfonamides; Virus Internalization	2015
Antiviral Efficacy of a Respiratory Syncytial Virus (RSV) Fusion Inhibitor in a Bovine Model of RSV Infection. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Animals; Antiviral Agents; Bronchiolitis; Cattle; Cattle Diseases; Cell Line; Cell Membrane; Double-Blind Method; Humans; Indazoles; Lung; Male; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Bovine; Respiratory Syncytial Virus, Human; Sulfonamides; Viral Load	2015

Other Studies

4 other study(ies) available for indazoles and Respiratory Syncytial Virus Infections

Article	Year
Discovery of methylsulfonyl indazoles as potent and orally active respiratory syncytial Virus(RSV) fusion inhibitors. European journal of medicinal chemistry, 2017, Sep-29, Volume: 138 Topics: Administration, Oral; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Drug Discovery; Humans; Indazoles; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Rats; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Structure-Activity Relationship	2017
Progress in the prevention and treatment of RSV infection. The New England journal of medicine, 2014, Aug-21, Volume: 371, Issue:8 Topics: Antiviral Agents; Female; Humans; Indazoles; Male; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Sulfonamides	2014
GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:11 Topics: Antiviral Agents; Indazoles; Protein Conformation; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Sulfonamides; Viral Proteins	2015
GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process. Antimicrobial agents and chemotherapy, 2015, Dec-14, Volume: 60, Issue:3 Topics: Antiviral Agents; Bronchi; Cell Fusion; Cell Line; Drug Evaluation, Preclinical; Drug Resistance, Viral; Humans; Indazoles; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Sulfonamides; Virus Internalization	2015