indazoles has been researched along with Osteogenic Sarcoma in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 8 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, L; Li, A; Li, X; Liu, W; Liu, Z; Qin, S; Wang, P; Xiong, X; Zhang, J; Zhang, Z | 1 |
| Chen, L; Cheng, S; Li, B; Lin, Z; Wang, M; Wang, W; Yao, M; Yin, Q; Zhang, Y | 1 |
| Bach, S; Baratte, B; Ben Salah, S; Berteina-Raboin, S; Bescond, A; Bonnet, P; Buron, F; Carles, F; Chaikuad, A; Chartier, A; Desban, N; Duez, J; Elie, J; Fant, X; Feizbakhsh, O; Josselin, B; Knapp, S; Marie, D; Place, M; Routier, S; Ruchaud, S | 1 |
| Du, C; He, G; Liu, X; Ma, Y; Mao, C; Pan, X; Zhu, Y | 1 |
| Higuchi, T; Hoffman, RM; Kanaya, F; Miyake, K; Nishida, K; Oshiro, H; Sugisawa, N; Tome, Y | 1 |
| Abbinanti, S; Agulnik, M; Attia, S; Cehic, R; Charlson, J; Helenowski, I; Hirbe, AC; Milhem, M; Mohindra, N; Monga, V; Okuno, S; Oppelt, P; Robinson, S; Schulte, B; Van Tine, BA | 1 |
| Hiramatsu, H; Hiraoka, S; Kato, I; Kosaka, T; Mizowaki, T; Sakamoto, A; Takita, J; Umeda, K; Uto, M | 1 |
| Adachi, S; Kato, I; Okamoto, T; Saida, S; Umeda, K | 1 |
| Abate, ME; Boye, K; Cesari, M; Donati, D; Hompland, I; Longhi, A; Paioli, A; Palmerini, E; Setola, E; Spinnato, P | 1 |
| Akers, LJ; Albritton, KH; Basha, R; Elete, KR; Ray, A | 1 |
| Hayashi, K; Igarashi, K; Miwa, S; Takeuchi, A; Tsuchiya, H; Yamamoto, N | 1 |
| Boysen, A; Lücke, A; Rossen, P; Safwat, A | 1 |
| Cao, W; Dai, L; Liang, W; Liu, Z; Qin, S; Xiong, X; Ye, D; Zhang, J | 1 |
| Baruchel, S; Kerbel, RS; Kumar, S; Man, S; Mokhtari, RB; Oliveira, ID; Sheikh, R; Wu, B; Xu, P; Yeger, H; Zhang, L | 1 |
| Cao, J; Guo, B; Liang, D; Yang, L; Yang, M; Zhang, X | 1 |
| Araki, N; Itoh, K; Naka, N; Tanaka, T; Wakamatsu, T; Yoshikawa, H; Yoshioka, K; Yui, Y | 1 |
1 review(s) available for indazoles and Osteogenic Sarcoma
| Article | Year |
|---|---|
Therapeutic Targets for Bone and Soft-Tissue Sarcomas.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bone Neoplasms; Drug Therapy; Furans; Humans; Immunotherapy, Adoptive; Indazoles; Ipilimumab; Ketones; Nivolumab; Osteosarcoma; Progression-Free Survival; Pyrimidines; Sarcoma; Soft Tissue Neoplasms; Sorafenib; Sulfonamides; Trabectedin | 2019 |
1 trial(s) available for indazoles and Osteogenic Sarcoma
| Article | Year |
|---|---|
Phase II study of pazopanib with oral topotecan in patients with metastatic and non-resectable soft tissue and bone sarcomas.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Administration Schedule; Humans; Indazoles; Male; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Prospective Studies; Pyrimidines; Sarcoma; Sulfonamides; Topotecan; Treatment Outcome; Young Adult | 2021 |
14 other study(ies) available for indazoles and Osteogenic Sarcoma
| Article | Year |
|---|---|
GSK343 induces programmed cell death through the inhibition of EZH2 and FBP1 in osteosarcoma cells.
Topics: Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Fructose-Bisphosphatase; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Osteosarcoma; Pyridones; Tumor Cells, Cultured | 2020 |
Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma.
Topics: Animals; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glycine; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Indazoles; Microwaves; Osteosarcoma; Quinoxalines; Rabbits; Radiofrequency Ablation; Transforming Growth Factor beta1; Tumor Burden | 2020 |
Design of new disubstituted imidazo[1,2-
Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Bone Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cyclin B; Drug Screening Assays, Antitumor; Histones; Humans; Indazoles; Intracellular Signaling Peptides and Proteins; Molecular Docking Simulation; Osteosarcoma; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridazines; Structure-Activity Relationship | 2020 |
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
Topics: Antineoplastic Agents; Bone Neoplasms; Cell Death; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Nanoparticles; Osteosarcoma; Particle Size; RNA, Small Interfering; Surface Properties; Tumor Cells, Cultured; Tumor Microenvironment; Zinc Oxide | 2020 |
An mTOR and VEGFR inhibitor combination arrests a doxorubicin resistant lung metastatic osteosarcoma in a PDOX mouse model.
Topics: Adolescent; Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Everolimus; Female; Humans; Indazoles; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Pyrimidines; Receptors, Vascular Endothelial Growth Factor; Sulfonamides; TOR Serine-Threonine Kinases | 2021 |
Radiation recall myositis caused by pazopanib in a patient with refractory osteosarcoma.
Topics: Humans; Indazoles; Myositis; Osteosarcoma; Pyrimidines; Sulfonamides | 2021 |
Pazopanib for second recurrence of osteosarcoma in pediatric patients.
Topics: Adolescent; Angiogenesis Inhibitors; Bone Neoplasms; Child; Female; Humans; Indazoles; Liver Neoplasms; Lung Neoplasms; Male; Osteosarcoma; Pyrimidines; Sulfonamides | 2017 |
Pazopanib in relapsed osteosarcoma patients: report on 15 cases.
Topics: Adolescent; Adult; Aged; Angiogenesis Inhibitors; Bone Neoplasms; Child; Female; Humans; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Progression-Free Survival; Pyrimidines; Salvage Therapy; Sulfonamides; Young Adult | 2019 |
Response to Pazopanib in Patients With Relapsed Osteosarcoma.
Topics: Adult; Bone Neoplasms; Female; Humans; Indazoles; Male; Neoplasm Recurrence, Local; Osteosarcoma; Pyrimidines; Sulfonamides | 2020 |
Pazopanib in metastatic osteosarcoma: significant clinical response in three consecutive patients.
Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Female; Humans; Humerus; Indazoles; Lung Neoplasms; Male; Neoplasms, Radiation-Induced; Osteosarcoma; Pyrimidines; Skull Neoplasms; Sulfonamides; Young Adult | 2014 |
Fuse-binding protein 1 is a target of the EZH2 inhibitor GSK343, in osteosarcoma cells.
Topics: Apoptosis; Autophagy; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; DNA Helicases; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Humans; Indazoles; Osteosarcoma; Proto-Oncogene Proteins c-myc; Pyridones; RNA-Binding Proteins | 2016 |
Metronomic oral topotecan with pazopanib is an active antiangiogenic regimen in mouse models of aggressive pediatric solid tumor.
Topics: Administration, Metronomic; Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Line, Tumor; Endothelial Cells; Humans; Indazoles; Mice; Mice, Inbred NOD; Mice, SCID; Microvessels; Neoplasms; Neoplastic Cells, Circulating; Neovascularization, Pathologic; Neuroblastoma; Osteosarcoma; Pyrimidines; Random Allocation; Rhabdomyosarcoma; Stem Cells; Sulfonamides; Topoisomerase I Inhibitors; Topotecan; Xenograft Model Antitumor Assays | 2011 |
HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Microscopy, Fluorescence; Morpholines; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA Interference; Sesquiterpenes; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases | 2012 |
Dynamic analysis of lung metastasis by mouse osteosarcoma LM8: VEGF is a candidate for anti-metastasis therapy.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Movement; Cell Proliferation; Coculture Techniques; Immunoenzyme Techniques; Indazoles; Lung Neoplasms; Mice; Mice, Inbred C3H; Osteosarcoma; Pyrimidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2013 |