Page last updated: 2024-08-21

indazoles and Neutropenia

indazoles has been researched along with Neutropenia in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's11 (68.75)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Hashimoto, K; Kanao, H; Kawakami, K; Mori, Y; Shibata, N; Shimizu, H; Soejima, A; Sugisaki, T; Yamaguchi, M; Yokokawa, T; Yunokawa, M1
Ae, K; Ando, M; Ando, Y; Goto, T; Hamada, S; Hiraga, H; Kawai, A; Kobayashi, E; Kuwatsuka, Y; Matsumoto, Y; Naka, N; Nakayama, R; Nishida, Y; Ozaki, T; Takahashi, S; Tsuchiya, H; Ueda, T; Urakawa, H1
Bauer, S; Chemnitz, JM; Crysandt, M; Egerer, G; Grünwald, V; Ivanyi, P; Karch, A; Kasper, B; Kopp, HG; Kunitz, A; Lindner, LH; Liu, X; Richter, S; Schöffski, P; Schuler, M; Steffen, B; Stein, A; Zimmermann, S1
Gunderson, CC; Matulonis, U; Moore, KN1
Cao, Z; Deng, H; Hong, Z; Huang, Y; Wei, Y; Yuan, X; Zhang, W1
Bedard, PL; Bray, MR; Brokx, R; Bruce, J; Cescon, DW; Denny, T; Fletcher, G; Li, SW; Mak, TW; Pugh, TJ; Sampson, P; Slamon, DJ; Veitch, ZW; Wainberg, ZA; Yonemoto, LM1
Arndt, C; Ecke, TH; Eimer, C; Georgas, E; Gerullis, H; Otto, T1
Bycott, P; Chen, C; Chmielowska, E; de Besi, P; Havel, L; Ingrosso, A; Kim, S; Olszanski, AJ; Popat, S; Sawrycki, P; Schiller, JH; Swieboda-Sadlej, A; Twelves, C; Williams, JA1
Antonysamy, MA; Bliss, RL; Dudek, AZ; Fischer, JH; Ganesan, C; Jha, G; Obulareddy, SJ1
Bennouna, J; Botbyl, J; de Labareyre, C; Delord, JP; Deslandres, M; Ruiz-Soto, R; Senellart, H; Suttle, AB; Wixon, C1
Baculi, F; Bates, RJ; Bennett, B; Blease, K; Brown, H; Burnett, K; Celeridad, M; Chamberlain, P; Delgado, M; Ferguson, GD; Haelewyn, J; Hickman, M; Jackson, P; Jensen-Pergakes, K; LeBrun, L; Miyazawa, K; Nadolny, L; Nguyen, T; Packard, G; Pagarigan, B; Pierce, S; Plantevin-Krenitsky, V; Tang, Y; Tehrani, L; Torres, S; Xie, W; Xu, L1
Chuman, H; Hayashi, Y; Iwase, H; Kawai, A; Kobayashi, E; Makino, Y; Nakatani, F; Sano, T; Tanzawa, Y1
Aggarwal, R; Bartelink, I; Cripps, A; Grabowsky, J; Harb, A; Jahan, T; Leng, J; Mastroserio, I; Munster, PN; Pawlowska, N; Reinert, A; Ryan, CJ; Thomas, S; Truong, TG1
Bair, AH; Bycott, P; Chan, S; Joy, AA; Kim, S; Liau, KF; Lluch, A; Rosbrook, B; Rugo, HS; Soulieres, D; Stopeck, AT; Verma, S1
Bhopale, VM; Buerk, DG; Cameron, B; Fisher, D; Thom, SR; Zhang, J1
Anderson, PM; Arndt, CA; Krailo, MD; Liu-Mares, W; Reaman, GH1

Reviews

2 review(s) available for indazoles and Neutropenia

ArticleYear
Management of the toxicities of common targeted therapeutics for gynecologic cancers.
    Gynecologic oncology, 2018, Volume: 148, Issue:3

    Topics: Anemia; Angiogenesis Inhibitors; Antineoplastic Agents, Immunological; Autoimmune Diseases; Bevacizumab; Diarrhea; Epistaxis; Fatigue; Female; Genital Neoplasms, Female; Headache; Hemorrhage; Humans; Hypertension; Indazoles; Intestinal Perforation; Molecular Targeted Therapy; Nausea; Neutropenia; Poly(ADP-ribose) Polymerase Inhibitors; Precision Medicine; Proteinuria; Pyrimidines; Risk Assessment; Sulfonamides; Vomiting; Water-Electrolyte Imbalance

2018
Pazopanib has equivalent anti-tumor effectiveness and lower Total costs than Sunitinib for treating metastatic or advanced renal cell carcinoma: a meta-analysis.
    BMC cancer, 2019, May-23, Volume: 19, Issue:1

    Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Fatigue; Health Care Costs; Humans; Indazoles; Kidney Neoplasms; Liver; Middle Aged; Neutropenia; Pyrimidines; Retrospective Studies; Sulfonamides; Sunitinib; Thrombocytopenia; Treatment Outcome

2019

Trials

10 trial(s) available for indazoles and Neutropenia

ArticleYear
Phase II clinical trial of pazopanib for patients with unresectable or metastatic malignant peripheral nerve sheath tumors.
    International journal of cancer, 2021, 01-01, Volume: 148, Issue:1

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Indazoles; Male; Middle Aged; Neoplasm Grading; Neurofibrosarcoma; Neutropenia; Progression-Free Survival; Protein Kinase Inhibitors; Pyrimidines; Response Evaluation Criteria in Solid Tumors; Severity of Illness Index; Sulfonamides; Young Adult

2021
Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 10-20, Volume: 38, Issue:30

    Topics: Age Factors; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Chemotherapy-Induced Febrile Neutropenia; Doxorubicin; Drug Administration Schedule; Female; Humans; Indazoles; Male; Middle Aged; Neutropenia; Patient Reported Outcome Measures; Progression-Free Survival; Pyrimidines; Quality of Life; Sarcoma; Sulfonamides

2020
Safety and tolerability of CFI-400945, a first-in-class, selective PLK4 inhibitor in advanced solid tumours: a phase 1 dose-escalation trial.
    British journal of cancer, 2019, Volume: 121, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Humans; Indazoles; Indoles; Male; Middle Aged; Neoplasms; Neutropenia; Protein Serine-Threonine Kinases

2019
Combined treatment with pazopanib and vinflunine in patients with advanced urothelial carcinoma refractory after first-line therapy.
    Anti-cancer drugs, 2013, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Early Termination of Clinical Trials; Humans; Indazoles; Male; Neutropenia; Organoplatinum Compounds; Palliative Care; Prospective Studies; Pyrimidines; Salvage Therapy; Sulfonamides; Thrombocytopenia; Urologic Neoplasms; Vinblastine

2013
Randomised phase II study of axitinib or bevacizumab combined with paclitaxel/carboplatin as first-line therapy for patients with advanced non-small-cell lung cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Imidazoles; Indazoles; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Paclitaxel; Proportional Hazards Models; Treatment Outcome

2014
Phase I Study of Pazopanib and Ixabepilone in Patients With Solid Tumors.
    American journal of clinical oncology, 2016, Volume: 39, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytokines; Disease-Free Survival; E-Selectin; Epothilones; Fatigue; Female; Humans; Indazoles; Male; Middle Aged; Neoplasms; Neutropenia; Pyrimidines; Retreatment; Sulfonamides; Survival Rate; Thrombocytopenia

2016
A phase I open-label study of the safety, tolerability, and pharmacokinetics of pazopanib in combination with irinotecan and cetuximab for relapsed or refractory metastatic colorectal cancer.
    Investigational new drugs, 2015, Volume: 33, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Humans; Indazoles; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Protein Kinase Inhibitors; Pyrimidines; Recurrence; Sulfonamides; Topoisomerase I Inhibitors; Treatment Outcome

2015
Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Acetylation; Adult; Aged; Alanine Transaminase; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Benzofurans; Carcinoma, Renal Cell; Disease Progression; Disease-Free Survival; Drug Resistance; Drug Resistance, Neoplasm; Epigenesis, Genetic; Fatigue; Female; Gene Expression; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Indazoles; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Pyrimidines; Sulfonamides; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult

2017
Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Docetaxel; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Hypertension; Imidazoles; Indazoles; Middle Aged; Mucositis; Neoplasm Proteins; Neutropenia; Protein Kinase Inhibitors; Receptors, Vascular Endothelial Growth Factor; Taxoids; Thrombophilia

2011
Phase I study of CI-958 in children and adolescents with recurrent solid tumors.
    Cancer, 2001, Mar-15, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Hypotension; Indazoles; Infusions, Intravenous; Male; Neoplasms; Neutropenia

2001

Other Studies

4 other study(ies) available for indazoles and Neutropenia

ArticleYear
Serum Creatinine Elevation as a Risk Factor for Niraparib-induced Hematologic Toxicity.
    Anticancer research, 2023, Volume: 43, Issue:10

    Topics: Anemia; Creatinine; Female; Humans; Indazoles; Neutropenia; Ovarian Neoplasms; Risk Factors; Thrombocytopenia

2023
A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Arthritis, Experimental; Basophils; Cell Line; Collagen; Crystallography, X-Ray; Dose-Response Relationship, Drug; Edema; Eosinophils; Female; HEK293 Cells; Humans; Hypertension; Indazoles; Inflammation; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Neutropenia; Neutrophils; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Fc; Skin; Syk Kinase; Triazoles; Vascular Endothelial Growth Factor Receptor-2

2016
[A Case of Severe Hematological Toxicity in Response to Pazopanib].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:6

    Topics: Angiogenesis Inducing Agents; Female; Humans; Indazoles; Leiomyosarcoma; Middle Aged; Neutropenia; Pyrimidines; Recurrence; Retroperitoneal Neoplasms; Sulfonamides; Thrombocytopenia

2016
Neuronal nitric oxide synthase and N-methyl-D-aspartate neurons in experimental carbon monoxide poisoning.
    Toxicology and applied pharmacology, 2004, Feb-01, Volume: 194, Issue:3

    Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Carbon Monoxide Poisoning; Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Laser-Doppler Flowmetry; Male; Maze Learning; Mice; Mice, Knockout; Microelectrodes; Neurons; Neurotoxicity Syndromes; Neutropenia; Neutrophils; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Platelet Count; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine

2004