Page last updated: 2024-08-21

indazoles and Necrosis

indazoles has been researched along with Necrosis in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's3 (20.00)18.2507
2000's3 (20.00)29.6817
2010's8 (53.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bronk, SF; Gores, GJ; Hernandez, MC; Hirsova, P; Kabashima, A; Kaufmann, SH; Rizvi, S; Truty, MJ1
Fulda, S1
Fujisawa, M; Hinata, N; Jimbo, N; Shigemura, K; Shiraishi, Y; Terakawa, T1
Amantini, C; Berardi, R; Bonfili, L; Burattini, L; Cascinu, S; Eleuteri, AM; Farfariello, V; Liberati, S; Morelli, MB; Mozzicafreddo, M; Nabissi, M; Santoni, G; Santoni, M1
Bennett, KL; Bigenzahn, JW; Bruckner, M; Colinge, J; Fauster, A; Gridling, M; Huber, KV; Krautwald, S; Kubicek, S; Lardeau, CH; Linkermann, A; Parapatics, K; Rebsamen, M; Scorzoni, S; Stukalov, A; Superti-Furga, G1
Demizu, Y; Futani, H; Mohri, T; Okimoto, T; Sakagami, M; Terada, T; Tsukamoto, Y; Uwa, N1
Amantini, C; Bernardini, G; Cardinali, C; Morelli, MB; Nabissi, M; Santoni, A; Santoni, G; Santoni, M1
Choi, S; Cuny, GD; Degterev, A; Keys, H; Staples, RJ; Yuan, J1
Aoki, MS; Miyabara, EH; Moriscot, AS; Selistre-de-Araújo, HS; Tostes, RC1
Bhatia, M; Chevali, L; Guglielmotti, A; Ramnath, RD1
Choi, S; Cuny, GD; Degterev, A; Jagtap, PG; Keys, H; Yuan, J1
Dunn, D; Farnworth, M; Gyte, A; Lock, EA; Moore, RB; Simpson, MG; Widdowson, PS; Wyatt, I1
Dowsing, B; Guida, E; Hickey, MJ; Knight, KR; Morrison, WA; Phan, LH; Stewart, AG; Zhang, B1
Hsueh, W; Zhang, C1
Boranić, M; Gajsak, V; Jercić, J; Lelieveld, P; Mihalić, H; Radacić, M; Skarić, D; Skarić, V1

Reviews

1 review(s) available for indazoles and Necrosis

ArticleYear
Repurposing anticancer drugs for targeting necroptosis.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Drug Repositioning; Humans; Imidazoles; Indazoles; Necrosis; Oximes; Pyridazines; Pyrimidines; Reperfusion Injury; Sorafenib; Sulfonamides; Systemic Inflammatory Response Syndrome; Vemurafenib

2018

Other Studies

14 other study(ies) available for indazoles and Necrosis

ArticleYear
Fibroblast growth factor receptor inhibition induces loss of matrix MCL1 and necrosis in cholangiocarcinoma.
    Journal of hepatology, 2018, Volume: 68, Issue:6

    Topics: Animals; Bile Duct Neoplasms; Cell Death; Cell Line, Tumor; Cholangiocarcinoma; Humans; Indazoles; Indoles; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Necrosis; Oxidation-Reduction; Receptors, Fibroblast Growth Factor; Sulfonamides; Xenograft Model Antitumor Assays

2018
Total necrosis after sequential treatment with pazopanib followed by nivolumab in a patient with renal cell carcinoma involving the inferior vena cava.
    International journal of urology : official journal of the Japanese Urological Association, 2019, Volume: 26, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Humans; Indazoles; Kidney; Kidney Neoplasms; Necrosis; Neoadjuvant Therapy; Neoplasm Invasiveness; Nephrectomy; Nivolumab; Pyrimidines; Sulfonamides; Tomography, X-Ray Computed; Treatment Outcome; Vena Cava, Inferior

2019
Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells.
    British journal of cancer, 2013, Aug-20, Volume: 109, Issue:4

    Topics: Antineoplastic Agents; Autophagy; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Indazoles; Indoles; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Necrosis; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Reactive Oxygen Species; Sulfonamides; Sunitinib; Urinary Bladder Neoplasms

2013
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.
    Cell death & disease, 2015, May-21, Volume: 6

    Topics: 3T3 Cells; Animals; Apoptosis; Cell Line, Tumor; Fas-Associated Death Domain Protein; HEK293 Cells; HT29 Cells; Humans; Imidazoles; Indazoles; Jurkat Cells; L Cells; MAP Kinase Kinase Kinases; Mice; Necrosis; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Pyridazines; Pyrimidines; Receptor-Interacting Protein Serine-Threonine Kinases; Sulfonamides; Tumor Necrosis Factor-alpha

2015
An unexpected skin ulcer and soft tissue necrosis after the nonconcurrent combination of proton beam therapy and pazopanib: A case of myxofibrosarcoma.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:4

    Topics: Angiogenesis Inhibitors; Debridement; Fatal Outcome; Fibrosarcoma; Head and Neck Neoplasms; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Myxoma; Necrosis; Proton Therapy; Pyrimidines; Skin Ulcer; Soft Tissue Infections; Sulfonamides; Tomography, X-Ray Computed

2017
Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner.
    Oncotarget, 2017, Jan-10, Volume: 8, Issue:2

    Topics: Axitinib; Bortezomib; Cell Death; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Gene Expression; Glioma; Humans; Imidazoles; Indazoles; Mitosis; Necrosis; Proteasome Inhibitors; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction

2017
Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability.
    Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

    Topics: Animals; Drug Stability; Humans; Indazoles; Jurkat Cells; Mice; Microsomes, Liver; Models, Molecular; Necrosis; Pyrazoles; Structure-Activity Relationship

2012
Role of nitric oxide in myotoxic activity induced by crotoxin in vivo.
    Toxicon : official journal of the International Society on Toxinology, 2004, Mar-15, Volume: 43, Issue:4

    Topics: Analysis of Variance; Animals; Brazil; Crotalus; Crotoxin; Guanidines; Histological Techniques; Indazoles; Muscle, Skeletal; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Signal Transduction

2004
Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:6

    Topics: Acute Disease; Animals; Ceruletide; Chemokine CCL2; Disease Models, Animal; Indazoles; Inflammation; Mice; Necrosis; Pancreas; Pancreatitis; Propionates

2005
Structure-activity relationship study of tricyclic necroptosis inhibitors.
    Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8

    Topics: Caspases; Cell Line; Fas-Associated Death Domain Protein; Heterocyclic Compounds, 3-Ring; Humans; Indazoles; Necrosis; Pyrazoles; Stereoisomerism; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2007
Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
    British journal of pharmacology, 1996, Volume: 117, Issue:8

    Topics: Animals; Aspartic Acid; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrocarbons, Chlorinated; In Vitro Techniques; Indazoles; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Propionates; Rats

1996
Timing of administration of dexamethasone or the nitric oxide synthase inhibitor, nitro-L-arginine methyl ester, is critical for effective treatment of ischaemia-reperfusion injury to rat skeletal muscle.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; DNA Probes; Enzyme Inhibitors; Indazoles; Isothiuronium; Male; Muscle, Skeletal; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

1997
PAF-induced bowel necrosis. Effects of vasodilators.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:5

    Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Mesenteric Arteries; Necrosis; Nitroglycerin; Phenoxybenzamine; Platelet Activating Factor; Prazosin; Rats; Rats, Inbred Strains; SRS-A; Vasodilator Agents

1991
Reduction of cis-dichlorodiammineplatinum(II) caused nephrotoxicity by indazolone carboxylic acid.
    Oncology, 1987, Volume: 44, Issue:1

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Cell Division; Cell Survival; Cisplatin; Indazoles; Kidney; Kidney Diseases; Leukemia L1210; Male; Mice; Mice, Inbred CBA; Necrosis; Pyrazoles

1987