Page last updated: 2024-08-21

indazoles and Muscle Relaxation

indazoles has been researched along with Muscle Relaxation in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (33.33)	18.2507
2000's	16 (59.26)	29.6817
2010's	2 (7.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gonzaga, NA; Leite, LN; Tirapelli, CR; Tirapelli, DP; Tirapelli, LF	1
Chen, YC; Du, GH; Fang, LH; Jiao, XZ; Li, L; Xie, P; Yuan, TY; Zhang, HF	1
Bonaventura, D; de Oliveira, AM; Tirapelli, CR	1
Aydin, C; Bagcivan, I; Koyuncu, A; Ozer, H; Soylu, S; Topcu, O; Yildirim, S	1
García-Flores, M; García-Pascual, A; Sancho, M; Triguero, D	1
Brioni, JD; Chang, R; Hsieh, GC; Kolasa, T; Miller, LN; Moreland, RB; Nakane, M	1
Favre, J; Laude, K; Richard, V; Thuillez, C	1
Che, Y; Li, CG; Rand, MJ	1
Cole, KR; Lanning, KM; Linder, AE; McCluskey, LP; Webb, RC	1
Bagcivan, I; Cetin, A; Cetin, M; Demirkoprulu, N; Karadas, B; Kaya, T; Soydan, AS	1
Che, Y; Ellis, A; Li, CG	1
D'Alecy, LG; Linder, AE; Webb, RC; Weber, DS; Whitesall, SE	1
Cogolludo, A; González-Luis, G; Lodi, F; Moreno, L; Pérez-Vizcaíno, F; Tamargo, J; Villamor, E	1
Bagcivan, I; Duman, M; Karadas, B; Kaya, T; Sarac, B; Turan, M	1
Abram, TS; Cuthbert, NJ; Gardiner, PJ; Jennings, MA; Maxey, RJ; Norman, P; Thompson, AM; Tudhope, SR	1
Bloomquist, W; Calligaro, DA; Cohen, I; Cohen, ML; Schaus, JM; Susemichel, AD; Thompson, DC	1
Bauersachs, J; Busse, R; Kast, R; Mülsch, A; Schäfer, A; Stasch, JP	1
Nawrath, H; Wegener, JW	1
Galle, J; Hatzelmann, A; Hübner, U; Schmidt, HH; Wagner, B; Wanner, C; Zabel, U	1
Hwang, TL; Teng, CM; Wu, CC	1
Gerhard, R; Jost, A; Nawrath, H; Ochi, R; Rupp, J; Seitz, S; Shainberg, A; Watanabe, M; Wegener, JW	1
Linz, W; Malinski, T; Ruetten, H; Schindler, U; Schoenafinger, K; Strobel, H; Wiemer, G; Wohlfart, P	1
Ekblad, E	1
Brien, JF; Choi, C; Chretien, ML; Marks, GS; McLaughlin, BE; Nakatsu, K	1
Antunes, E; De Nucci, G; Teixeira, CE; Teixeira, SA	1
Brien, JF; Marks, GS; McLaughlin, BE; Nakatsu, K; O'Reilly, DA	1
Andersson, KE; Hedlund, P; Schroder, A	1

Other Studies

27 other study(ies) available for indazoles and Muscle Relaxation

Article	Year
Pharmacological characterization of the relaxant effect induced by adrenomedullin in rat cavernosal smooth muscle. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2014, Volume: 47, Issue:10 Topics: 4-Aminopyridine; 6-Ketoprostaglandin F1 alpha; Adrenomedullin; Animals; Blotting, Western; Calcitonin Receptor-Like Protein; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; Indazoles; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Parasympatholytics; Penis; Potassium Channels, Voltage-Gated; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Protein 3; Receptors, Calcitonin Gene-Related Peptide; RNA, Messenger; Vasodilator Agents	2014
DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes. Acta pharmacologica Sinica, 2016, Volume: 37, Issue:5 Topics: Actins; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Calcium; In Vitro Techniques; Indazoles; Male; Molecular Docking Simulation; Muscle Contraction; Muscle Relaxation; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphorylation; Protein Phosphatase 1; Rats, Sprague-Dawley; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents; Vasodilator Agents	2016
Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid. Amino acids, 2009, Volume: 37, Issue:4 Topics: Animals; Bradykinin; Cardiovascular Agents; Carotid Arteries; Chronic Disease; Enzyme Inhibitors; Hyperhomocysteinemia; Indazoles; Indomethacin; Male; Methionine; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandin Antagonists; Rats; Rats, Wistar; Receptors, Thromboxane A2, Prostaglandin H2; Vasodilator Agents; Xanthones	2009
Effect of nitric oxide/cyclic guanosine mono-phosphate pathway on gallbladder relaxant response in bile duct-ligated guinea pigs. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2009, Volume: 42, Issue:3 Topics: Amrinone; Animals; Arginine; Bile Ducts; Cyclic GMP; Gallbladder; Guanidines; Guinea Pigs; Hydrazines; In Vitro Techniques; Indazoles; Ligation; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Papaverine; Piperazines; Purines; Sildenafil Citrate; Sulfones	2009
Presence of cyclic nucleotide-gated channels in the rat urethra and their involvement in nerve-mediated nitrergic relaxation. American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:5 Topics: Animals; Calcium Channel Blockers; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Indazoles; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stereoisomerism; Urethra	2009
A-350619: a novel activator of soluble guanylyl cyclase. Life sciences, 2003, Jan-17, Volume: 72, Issue:9 Topics: Acrylamides; Animals; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Penile Erection; Rabbits; Rats; Rats, Wistar; Spodoptera	2003
NO produced by endothelial NO synthase is a mediator of delayed preconditioning-induced endothelial protection. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6 Topics: Acetylcholine; Animals; Blood Pressure; Blood Vessels; Coronary Vessels; Endothelium, Vascular; Free Radical Scavengers; Heart Rate; In Vitro Techniques; Indazoles; Ischemic Preconditioning, Myocardial; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Vasodilator Agents	2003
Inhibition by ebselen on nitric oxide mediated relaxations in the rat anococcygeus muscle. European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3 Topics: Animals; Aorta; Azoles; Copper; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Activators; Enzyme Inhibitors; Glutathione; In Vitro Techniques; Indazoles; Isoindoles; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Organoselenium Compounds; Papaverine; Penicillamine; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Vasodilation	2003
Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1 Topics: Acetylcholine; Animals; beta-Cyclodextrins; Caveolae; Caveolin 1; Caveolins; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Immunohistochemistry; In Vitro Techniques; Indazoles; Isometric Contraction; Male; Microscopy, Electron; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents	2005
Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium. European journal of pharmacology, 2005, Jul-11, Volume: 517, Issue:3 Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indazoles; Male; Methylene Blue; Muscle Relaxation; Myometrium; Nitric Oxide Donors; Pregnancy; Rats; Rats, Wistar; Time Factors; Triazenes; Uterine Contraction	2005
Enhanced responsiveness to nitric oxide, nitroxyl anions, and nitrergic transmitter by 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole in the rat anococcygeus muscle. Nitric oxide : biology and chemistry, 2005, Volume: 13, Issue:2 Topics: Animals; Electric Stimulation; Indazoles; Male; Muscle Relaxation; Muscle, Skeletal; Neurotransmitter Agents; Nitrergic Neurons; Nitric Oxide; Nitrogen Oxides; Rats; Rats, Sprague-Dawley	2005
Altered vascular reactivity in mice made hypertensive by nitric oxide synthase inhibition. Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4 Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activators; Enzyme Inhibitors; Heart Rate; Hypertension; In Vitro Techniques; Indazoles; Male; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenylephrine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2005
Relaxant effects of the soluble guanylate cyclase activator and NO sensitizer YC-1 in piglet pulmonary arteries. Biology of the neonate, 2006, Volume: 90, Issue:1 Topics: Animals; Animals, Newborn; Enzyme Activators; Guanylate Cyclase-Activating Proteins; Indazoles; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Platelet Aggregation Inhibitors; Pulmonary Artery; Swine; Vasodilation	2006
Comparative relaxant effects of YC-1 and DEA/NO on the sheep sphincter of Oddi. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2006, Volume: 6, Issue:3 Topics: Animals; Cyclic GMP; Hydrazines; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; Neuromuscular Blocking Agents; Nitrogen Oxides; Sheep; Sphincter of Oddi	2006
BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3 Topics: Animals; Binding, Competitive; Bronchi; Dicarboxylic Acids; Ferrets; Guinea Pigs; In Vitro Techniques; Indazoles; Leukotriene C4; Leukotriene D4; Lung; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propionates; Quinolines; Rats; Rats, Wistar; Receptors, Immunologic; Sheep; Spleen; SRS-A; Trachea	1994
LY353433, a potent, orally effective, long-acting 5-HT(4) receptor antagonist: comparison to cisapride and RS23597-190. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1 Topics: Adamantane; Administration, Oral; Aminobenzoates; Animals; Cisapride; Esophagus; Female; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; para-Aminobenzoates; Piperidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Serotonin Antagonists	1996
Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators. British journal of pharmacology, 1997, Volume: 120, Issue:4 Topics: Animals; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits; Rats; Rats, Inbred WKY; Superoxides; Vasodilator Agents	1997
Differential effects of isoliquiritigenin and YC-1 in rat aortic smooth muscle. European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1 Topics: Aldehyde Reductase; Animals; Carotid Arteries; Chalcone; Chalcones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Indazoles; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley	1997
Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity. British journal of pharmacology, 1999, Volume: 127, Issue:1 Topics: Animals; Aorta, Thoracic; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indazoles; Isoenzymes; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxadiazoles; Phosphoric Diester Hydrolases; Quinoxalines; Rabbits; Vasodilator Agents	1999
YC-1 potentiates nitric oxide-induced relaxation in guinea-pig trachea. British journal of pharmacology, 1999, Volume: 128, Issue:3 Topics: Animals; Cyclic AMP; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; Nitric Oxide; Superoxides; Trachea	1999
Involvement of K(+) channels in the relaxant effects of YC-1 in vascular smooth muscle. European journal of pharmacology, 1999, Oct-01, Volume: 382, Issue:1 Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Indazoles; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilation	1999
Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylyl cyclase. British journal of pharmacology, 1999, Volume: 128, Issue:6 Topics: Animals; Aorta, Thoracic; Bradykinin; Calcimycin; Cattle; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Ionophores; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Solubility; Time Factors	1999
Pharmacological evidence for both neuronal and smooth muscular PAC1 receptors and a VIP-specific receptor in rat colon. Regulatory peptides, 1999, Dec-23, Volume: 85, Issue:2-3 Topics: Animals; Apamin; Colon; Female; Indazoles; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pituitary Adenylate Cyclase-Activating Polypeptide; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Tetrodotoxin; Vasoactive Intestinal Peptide	1999
Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole]. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:4 Topics: Animals; Aorta, Thoracic; Carbon Monoxide; Drug Synergism; Guanylate Cyclase; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley	2000
The role of nitric oxide on the relaxations of rabbit corpus cavernosum induced by Androctonus australis and Buthotus judaicus scorpion venoms. Toxicon : official journal of the International Society on Toxinology, 2001, Volume: 39, Issue:5 Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Drug Interactions; Enzyme Inhibitors; Indazoles; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penis; Rabbits; Scopolamine; Scorpion Venoms; Stereoisomerism; Tetrodotoxin	2001
YC-1 enhances the responsiveness of tolerant vascular smooth muscle to glyceryl trinitrate. Canadian journal of physiology and pharmacology, 2001, Volume: 79, Issue:1 Topics: Animals; Aorta, Thoracic; Cyclic GMP; Drug Tolerance; Enzyme Activators; In Vitro Techniques; Indazoles; Isometric Contraction; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Rabbits; Vasodilator Agents	2001
Carbon monoxide relaxes the female pig urethra as effectively as nitric oxide in the presence of YC-1. The Journal of urology, 2002, Volume: 167, Issue:4 Topics: Animals; Carbon Monoxide; Electric Stimulation; Enzyme Activators; Female; Indazoles; Muscle Relaxation; Nitric Oxide; Swine; Urethra	2002