Page last updated: 2024-08-21

indazoles and Leukemia, Lymphoblastic, Acute, T Cell

indazoles has been researched along with Leukemia, Lymphoblastic, Acute, T Cell in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Aster, JC; Craig, JW; Dail, M; Downing, JR; Hasserjian, RP; Hayes, K; Huang, BJ; Jonsson, P; Kogan, SC; Li, Q; Meyer, LK; Monsalve, G; Nakitandwe, J; Sampath, D; Scacchetti, A; Shannon, K; Taylor, BS; Wandler, AM; Weinberg, O; Wong, JC; Yamamoto, K; Yan, H; Zhang, J1
Donker, L; Ducker, GS; Jun, J; Ksionda, O; Matlawska-Wasowska, K; Mues, M; Roose, JP; Shannon, K; Shokat, KM; Tenhagen, M; Wandler, AM1
Akagi, K; Aster, JC; Chen, SC; Dail, M; Downing, JR; Lawrence, J; Lee, LB; Li, Q; Nakitandwe, J; O'Connor, D; Pear, WS; Sampath, D; Shannon, K; Wong, J; Xu, J1
Bressanin, D; Buontempo, F; Chiarini, F; Evangelisti, C; Martelli, AM; McCubrey, JA; Melchionda, F; Pagliaro, P; Pession, A; Ricci, F; Tabellini, G; Tazzari, PL1

Other Studies

5 other study(ies) available for indazoles and Leukemia, Lymphoblastic, Acute, T Cell

ArticleYear
Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia.
    Leukemia, 2020, Volume: 34, Issue:8

    Topics: Animals; Dexamethasone; Drug Resistance, Neoplasm; Humans; Indazoles; Male; Mice; Mice, Inbred C57BL; Mutation; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Glucocorticoid; Recurrence; Sulfonamides

2020
Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Animals; Apoptosis; Cell Proliferation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.
    Nature, 2014, Sep-25, Volume: 513, Issue:7519

    Topics: Animals; Benzamides; Clone Cells; Diphenylamine; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Genes, ras; Indazoles; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Phosphoinositide-3 Kinase Inhibitors; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Receptor, Notch1; Signal Transduction; Sulfonamides

2014
NOTCH1 downregulation contributes to PI3K inhibitor resistance in T-ALL.
    Cancer discovery, 2014, Volume: 4, Issue:9

    Topics: Animals; Drug Resistance, Neoplasm; Indazoles; Male; Phosphoinositide-3 Kinase Inhibitors; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Receptor, Notch1; Sulfonamides

2014
Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels.
    Oncotarget, 2012, Volume: 3, Issue:8

    Topics: Adult; Caspase 3; Cell Line, Tumor; Child; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Indazoles; Molecular Targeted Therapy; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinolines; Signal Transduction; Sulfonamides; T-Lymphocytes; TOR Serine-Threonine Kinases

2012