indazoles has been researched along with Invasiveness, Neoplasm in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 30 (88.24) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Alburquerque-González, B; Bernabé-García, Á; Bernabé-García, M; Cayuela, ML; Conesa-Zamora, P; den-Haan, H; Luque, I; Montoro-García, S; Nicolás, FJ; Pérez-Sánchez, H; Rodrigues, PC; Salo, T | 1 |
| Chen, Y; Fang, X; Gao, Y; Hua, Y; Huang, C; Li, H; Liu, H; Lu, S; Lu, T; Wang, C; Wang, M; Wang, Z; Zhang, M; Zhang, T; Zhang, Y; Zhu, L | 1 |
| Chen, C; Chen, J; Gong, H; Li, W; Li, Y; Liu, C; Liu, H; Liu, M; Shi, R; Yuan, Y; Zhang, H; Zhang, Z | 1 |
| Dai, J; Hu, Y; Li, X; Wang, Y; Williams, BR; Xu, D; Xu, P; Yan, F; Ying, L; Zhao, Y | 1 |
| Bastholt, L; Bengtsen, C; Jensen, BL; Jensen, NV; Madsen, K; Tinning, AR | 1 |
| Cheng, L; Li, X; Yang, F; Zhang, L | 1 |
| Basso, U; Berardi, R; Bersanelli, M; Burattini, L; Buti, S; Conti, A; De Giorgi, U; Iuliani, M; Lolli, C; Maruzzo, M; Mazzucchelli, R; Montironi, R; Mosca, A; Piva, F; Santini, D; Santoni, M; Terrone, C | 1 |
| Al-Kawaz, A; Ali, R; Band, V; Green, AR; Madhusudan, S; Mesquita, KA; Miligy, IM; Mirza, S; Rakha, EA; Seedhouse, C; Toss, MS | 1 |
| Fujisawa, M; Hinata, N; Jimbo, N; Shigemura, K; Shiraishi, Y; Terakawa, T | 1 |
| Gao, H; Guo, X; Li, X; Liu, N; Peng, S; Wang, K; Wu, W; Yu, J; Zhan, G; Zhu, Y | 1 |
| Christian, S; Danciu, OC; Dudek, AZ; Fischer, JH; Liu, LC; Russell, MJ; Shah, HA; Venepalli, NK; Zacny, JP | 1 |
| Amatangelo, MD; Conejo-Garcia, JR; Garipov, A; Li, H; Speicher, DW; Zhang, R | 1 |
| Gallo, KA; Wu, X | 1 |
| Calogero, A; Ciccone, AM; De Falco, E; Ibrahim, M; Menna, C; Pacini, L; Petrozza, V; Puca, R; Rendina, EA; Ruggieri, P; Scafetta, G | 1 |
| Bible, KC; Bossou, AR; Cradic, KW; Grebe, SK; Isham, CR; Milosevic, D; Netzel, BC | 1 |
| Deng, LL; Lin, P; Liu, Y; Lu, C; Qin, Z; Sun, L | 1 |
| Chen, J; Ding, M; Gao, Y; Li, Z; Shi, L; Wang, C; Xu, D; Zhang, H | 1 |
| Bhattacharyya, H; Casey, M; Chakrabarti, D; Chan, SL; Chen, C; Kang, YK; Kim, RD; Kudo, M; Lee, TY; Lim, HY; Obi, S; Park, JW; Qin, S; Valota, O; Williams, JA; Yau, T | 1 |
| Beaumont, JL; Cella, D; Diaz, J; Khan, S; Lai, JS | 1 |
| Barat, S; Bozko, P; Chen, X; Götze, J; Hanert, F; Malek, NP; Plentz, RR; Scholta, T; Wilkens, L | 1 |
| Jung, SH; Kang, WK; Kim, ST; Lee, J; Lee, SJ; Lim, HY; Park, JO; Park, SH; Park, YS | 1 |
| Kaneko, T; Shinkai, M; Watanabe, K | 1 |
| Abe, H; Arai, K; Fukuda, T; Kamai, T; Masuda, A; Nukui, A; Yoshida, K | 1 |
| Fujisaki, A; Komatsubara, M; Kurokawa, S; Morita, T; Yamazaki, M | 1 |
| Bawa, O; Bosq, J; Daudigeos-Dubus, E; Geoerger, B; Le Dret, L; Opolon, P; Vassal, G; Vievard, A; Villa, I | 1 |
| Guo, H; Liu, H; Liu, J; Liu, T; Shi, F; Wu, L; Wu, Q; Zhang, Q; Zhang, R | 1 |
| Chan, AT; Cheng, SH; Hong, B; Hui, EP; Leung, HS; Lu, Y; Lui, VW; Mills, GB; Ng, MH; Wong, EY | 1 |
| Greten, TF; Manns, MP; Plentz, RR | 1 |
| Gou, S; Liu, T; Wang, C; Wang, L; Wang, T; Zhou, W | 1 |
| Agulnik, M; Chia, S; Clemons, M; Dent, S; Grenci, P; Ivy, P; Leighl, NB; Oza, AM; Pritchard, KI; Taylor, SK; Wang, L | 1 |
| Bae, K; Dai, Y; Siemann, DW | 1 |
| Barranger, E; Camus, M; Eveno, C; le Maignan, C; Pocard, M; Soyer, P | 1 |
| Chikh, A; Falasca, M; Maffucci, T; Raimondi, C; Wheeler, AP | 1 |
| Chun, YS; Jeong, JM; Jung, YJ; Kim, JH; Kim, KE; Park, JW; Shin, DH | 1 |
1 review(s) available for indazoles and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Molecular therapy of pancreatic cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Benzenesulfonates; Bevacizumab; Capecitabine; Carcinoma, Pancreatic Ductal; Cetuximab; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Deoxycytidine; ErbB Receptors; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Humans; Imidazoles; Indazoles; Neoplasm Invasiveness; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Phthalazines; Prognosis; Pyridines; Quinazolines; Randomized Controlled Trials as Topic; Risk Assessment; Sorafenib; Survival Analysis; Treatment Outcome; Vascular Endothelial Growth Factor A | 2010 |
5 trial(s) available for indazoles and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Phase I Study of Aurora A Kinase Inhibitor Alisertib (MLN8237) in Combination With Selective VEGFR Inhibitor Pazopanib for Therapy of Advanced Solid Tumors.
Topics: Adult; Age Factors; Aged; Azepines; Cohort Studies; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Indazoles; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms; Patient Safety; Pyrimidines; Response Evaluation Criteria in Solid Tumors; Retrospective Studies; Risk Assessment; Sex Factors; Sulfonamides; Survival Analysis; Treatment Outcome | 2019 |
Randomized phase II study of axitinib versus placebo plus best supportive care in second-line treatment of advanced hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Axitinib; Carcinoma, Hepatocellular; Double-Blind Method; Female; Humans; Imidazoles; Indazoles; Liver Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Palliative Care; Survival Rate; Treatment Outcome | 2015 |
Validation of a short questionnaire to measure symptoms and functional limitations associated with hand-foot syndrome and mucositis in patients with metastatic renal cell carcinoma.
Topics: Adult; Aged; Carcinoma, Renal Cell; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Hand-Foot Syndrome; Humans; Indazoles; Indoles; Kidney Neoplasms; Lymph Nodes; Male; Maximum Tolerated Dose; Middle Aged; Mucositis; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Pyrimidines; Pyrroles; Quality of Life; Risk Assessment; Sulfonamides; Sunitinib; Surveys and Questionnaires; Treatment Outcome | 2016 |
Prospective phase II trial of pazopanib plus CapeOX (capecitabine and oxaliplatin) in previously untreated patients with advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Female; Follow-Up Studies; Humans; Indazoles; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Organoplatinum Compounds; Oxaliplatin; Prognosis; Prospective Studies; Pyrimidines; Stomach Neoplasms; Sulfonamides; Young Adult | 2016 |
A phase II study of pazopanib in patients with recurrent or metastatic invasive breast carcinoma: a trial of the Princess Margaret Hospital phase II consortium.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Breast Neoplasms; Disease Progression; ErbB Receptors; Female; Humans; Indazoles; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platelet-Derived Growth Factor; Pyrimidines; Sulfonamides | 2010 |
28 other study(ies) available for indazoles and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Survival; Colorectal Neoplasms; Embryo, Nonmammalian; Humans; Indazoles; Microfilament Proteins; Models, Molecular; Neoplasm Invasiveness; Zebrafish | 2020 |
Design and synthesis of 1H-indazole-3-carboxamide derivatives as potent and selective PAK1 inhibitors with anti-tumour migration and invasion activities.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Chemistry Techniques, Synthetic; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Indazoles; Inhibitory Concentration 50; Neoplasm Invasiveness; p21-Activated Kinases; Protein Kinase Inhibitors | 2020 |
EZH2 inhibitors reverse resistance to gefitinib in primary EGFR wild-type lung cancer cells.
Topics: Adenosine; Adult; Aged; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Genes, erbB-1; Humans; Indazoles; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Protein Kinase Inhibitors; Pyridones; RNA Interference; RNA, Neoplasm; RNA, Small Interfering; Signal Transduction | 2020 |
(-)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enhancer of Zeste Homolog 2 Protein; Humans; Indazoles; Neoplasm Invasiveness; Pyridones | 2018 |
Pazopanib-Induced Hypertension in Patients With Renal Cell Carcinoma Is Associated With Low Urine Excretion of NO Metabolites.
Topics: Administration, Oral; Aged; Carcinoma, Renal Cell; Cohort Studies; Denmark; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Glomerular Filtration Rate; Hospitals, University; Humans; Hypertension; Indazoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitric Oxide; Prospective Studies; Pyrimidines; Risk Assessment; Sulfonamides; Time Factors | 2018 |
LncRNA TUG1 promoted viability and associated with gemcitabine resistant in pancreatic ductal adenocarcinoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Movement; Cell Survival; Cells, Cultured; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression; Humans; Indazoles; Neoplasm Invasiveness; Pancreatic Neoplasms; Piperazines; RNA, Long Noncoding | 2018 |
Autophagic Gene Polymorphisms in Liquid Biopsies and Outcome of Patients with Metastatic Clear Cell Renal Cell Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Autophagy; Autophagy-Related Proteins; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Follow-Up Studies; Humans; Indazoles; Kidney Neoplasms; Liquid Biopsy; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Polymorphism, Genetic; Prognosis; Pyrimidines; Retrospective Studies; Sulfonamides; Survival Rate | 2018 |
Targeting PARP1 in XRCC1-Deficient Sporadic Invasive Breast Cancer or Preinvasive Ductal Carcinoma
Topics: Apoptosis; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Line, Tumor; Chemoprevention; CRISPR-Cas Systems; DNA Breaks, Double-Stranded; DNA Repair; Female; Germ-Line Mutation; HeLa Cells; Humans; Indazoles; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Phthalazines; Piperazines; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Spheroids, Cellular; Synthetic Lethal Mutations; X-ray Repair Cross Complementing Protein 1 | 2018 |
Total necrosis after sequential treatment with pazopanib followed by nivolumab in a patient with renal cell carcinoma involving the inferior vena cava.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Humans; Indazoles; Kidney; Kidney Neoplasms; Necrosis; Neoadjuvant Therapy; Neoplasm Invasiveness; Nephrectomy; Nivolumab; Pyrimidines; Sulfonamides; Tomography, X-Ray Computed; Treatment Outcome; Vena Cava, Inferior | 2019 |
β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway.
Topics: Animals; Apoptosis; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chorionic Gonadotropin, beta Subunit, Human; Female; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Indazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Piperazines; Receptors, LH | 2019 |
Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition.
Topics: Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Female; Humans; Indazoles; Neoplasm Invasiveness; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polycomb Repressive Complex 2; Pyridones; Tumor Microenvironment | 2013 |
The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration.
Topics: Acinar Cells; Apoptosis; Benzodiazepinones; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Size; Disease Progression; Humans; Indazoles; Isoquinolines; Ligands; Mammary Glands, Human; Neoplasm Invasiveness; Receptors, GABA | 2013 |
Axitinib affects cell viability and migration of a primary foetal lung adenocarcinoma culture.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged, 80 and over; Antineoplastic Agents; Axitinib; Cell Movement; Cell Survival; Cisplatin; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Indazoles; Lung Neoplasms; Middle Aged; Neoplasm Invasiveness; Protein Kinase Inhibitors; Radiography; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A | 2014 |
Development and characterization of a differentiated thyroid cancer cell line resistant to VEGFR-targeted kinase inhibitors.
Topics: Animals; Carcinoma; Carcinoma, Papillary; Cell Culture Techniques; Cell Line, Tumor; DNA Mutational Analysis; Drug Resistance, Neoplasm; Humans; Indazoles; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Pyrimidines; ras Proteins; Receptors, Vascular Endothelial Growth Factor; Sulfonamides; Thyroid Cancer, Papillary; Thyroid Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Hypoxia promotes HO-8910PM ovarian cancer cell invasion via Snail-mediated MT1-MMP upregulation.
Topics: Animals; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen Type I; Extracellular Matrix; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Indazoles; Matrix Metalloproteinase 14; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; RNA, Small Interfering; Snail Family Transcription Factors; Transcription Factors; Up-Regulation | 2015 |
The polycomb group protein enhancer of zeste 2 is a novel therapeutic target for cervical cancer.
Topics: Animals; Cadherins; Carcinogenesis; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Indazoles; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Polycomb Repressive Complex 2; Pyridones; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Targeting c-MET by LY2801653 for treatment of cholangiocarcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bile Duct Neoplasms; Bile Ducts; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Female; Humans; Indazoles; Mice, Nude; Molecular Targeted Therapy; Neoplasm Invasiveness; Niacinamide; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Signal Transduction | 2016 |
Autopsy case of pulmonary artery sarcoma forming aneurysm without FDG uptake.
Topics: Adult; Aneurysm; Aneurysm, Ruptured; Fatal Outcome; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Indazoles; Leiomyosarcoma; Lung; Male; Neoplasm Invasiveness; Positron-Emission Tomography; Pulmonary Artery; Pyrimidines; Radiopharmaceuticals; Rupture, Spontaneous; Shock, Hemorrhagic; Sulfonamides; Vascular Neoplasms | 2016 |
Higher preoperative serum levels of PD-L1 and B7-H4 are associated with invasive and metastatic potential and predictable for poor response to VEGF-targeted therapy and unfavorable prognosis of renal cell carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Axitinib; B7-H1 Antigen; Biomarkers, Tumor; Carcinoma, Renal Cell; CD28 Antigens; Chemotherapy, Adjuvant; Female; Humans; Imidazoles; Indazoles; Indoles; Kaplan-Meier Estimate; Karnofsky Performance Status; Kidney Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Proteins; Nephrectomy; Preoperative Period; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; V-Set Domain-Containing T-Cell Activation Inhibitor 1; Vascular Endothelial Growth Factor A; Young Adult | 2016 |
Tumor Thrombus of Renal Cell Carcinoma Extending Into the Inferior Vena Cava, Ovarian Vein, and Ureter Treated With Neoadjuvant Axitinib.
Topics: Axitinib; Carcinoma, Renal Cell; Female; Humans; Imidazoles; Indazoles; Kidney Neoplasms; Middle Aged; Neoplasm Invasiveness; Neoplastic Cells, Circulating; Ovary; Ureteral Neoplasms; Veins; Vena Cava, Inferior | 2016 |
Dual inhibition using cabozantinib overcomes HGF/MET signaling mediated resistance to pan-VEGFR inhibition in orthotopic and metastatic neuroblastoma tumors.
Topics: Anilides; Animals; Apoptosis; Axitinib; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Hepatocyte Growth Factor; Humans; Imidazoles; Indazoles; Mice; Neoplasm Invasiveness; Neuroblastoma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Xenograft Model Antitumor Assays | 2017 |
The PI3K inhibitor GDC-0941 enhances radiosensitization and reduces chemoresistance to temozolomide in GBM cell lines.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Glioblastoma; Humans; Indazoles; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Radiation-Sensitizing Agents; Signal Transduction; Sulfonamides; Temozolomide | 2017 |
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.
Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Down-Regulation; Furans; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Protein Array Analysis; Protein Kinases; Protein Serine-Threonine Kinases; S Phase | 2010 |
Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1alpha pathway.
Topics: Cell Line, Tumor; Cell Proliferation; Guanylate Cyclase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Insulin; Neoplasm Invasiveness; Pancreatic Neoplasms; RNA, Messenger; Signal Transduction | 2010 |
Impact of hypoxia on the metastatic potential of human prostate cancer cells.
Topics: Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Neoplasm Proteins; Prostatic Neoplasms; Time Factors; Tumor Stem Cell Assay | 2011 |
Late anastomotic colonic dehiscence due to antiangiogenic treatment, a specific drug-class complication requiring specific treatment: an example of pazopanib complication.
Topics: Anastomosis, Surgical; Angiogenesis Inhibitors; Anti-Bacterial Agents; Carcinoma; Colectomy; Female; Humans; Hysterectomy; Indazoles; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Ovarian Neoplasms; Ovariectomy; Peritoneal Neoplasms; Pyrimidines; Salpingectomy; Sulfonamides; Surgical Wound Dehiscence; Treatment Outcome | 2011 |
A novel regulatory mechanism links PLCγ1 to PDK1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Calcium; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Indazoles; Neoplasm Invasiveness; Phospholipase C gamma; Phosphorylation; Protein Interaction Mapping; Protein Serine-Threonine Kinases; Pyrimidines; RNA, Small Interfering; Signal Transduction; Transfection | 2012 |
Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Collagen; Drug Combinations; Drug Screening Assays, Antitumor; Green Fluorescent Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Laminin; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Proteoglycans | 2007 |