indazoles has been researched along with Chagas Disease in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Arán, VJ; de Castro, S; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Ibáñez-Escribano, A | 1 |
| Arán, VJ; Batista, DDGJ; Batista, MM; Cumella, J; da Silva, CF; de Oliveira, GM; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Peres, RB; Silva da Gama Nefertiti, A; Soeiro, MNC | 1 |
| Aguilera-Venegas, B; Arán, VJ; Marín, C; Martín-Escolano, J; Martín-Escolano, R; Martín-Montes, Á; Medina-Carmona, E; Sánchez-Moreno, M | 1 |
| Aguilera-Venegas, B; Arán, VJ; Olea-Azar, C; Speisky, H | 1 |
| Arán, VJ; Marín, C; Muro, B; Navarro, P; Ramírez-Macías, I; Reviriego, F; Rosales, MJ; Sánchez-Moreno, M | 1 |
| Arán, VJ; Cumella, J; da Silva, PB; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Ibáñez-Escribano, A; Jagerovic, N; Morales, P; Nogal-Ruiz, JJ; Reviriego, F; Soeiro, Mde N | 1 |
| Arán, VJ; Batista, MM; DA Silva, CF; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Menna-Barreto, RF; Soeiro, Mde N | 1 |
| Arán, VJ; Boiani, L; Carrasco-Pozo, C; Cerecetto, H; Cosoy, HS; González, M; Lavaggi, ML; Maya, JD; Olea-Azar, C; Rodríguez, J | 1 |
| Atienza, J; Claramunt, RM; Elguero, J; Escario, JA; Gómez Barrio, A; Mester, B | 1 |
1 review(s) available for indazoles and Chagas Disease
| Article | Year |
|---|---|
Indazoles: a new top seed structure in the search of efficient drugs against Trypanosoma cruzi.
Topics: Chagas Disease; Drug Design; Humans; Indazoles; NADH, NADPH Oxidoreductases; Nifurtimox; Nitroimidazoles; Protozoan Proteins; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi | 2013 |
8 other study(ies) available for indazoles and Chagas Disease
| Article | Year |
|---|---|
5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents.
Topics: Chagas Disease; Humans; Indazoles; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2022 |
Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant
Topics: Animals; Cell Line; Chagas Disease; Drug Resistance; Drug Therapy, Combination; Humans; Indazoles; Mice; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi | 2020 |
Synthesis and Biological in vitro and in vivo Evaluation of 2-(5-Nitroindazol-1-yl)ethylamines and Related Compounds as Potential Therapeutic Alternatives for Chagas Disease.
Topics: Animals; Chagas Disease; Chlorocebus aethiops; DNA; Enzyme Inhibitors; Ethylamines; Female; Indazoles; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Neglected Diseases; RNA; Superoxide Dismutase; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2018 |
New perspectives on the synthesis and antichagasic activity of 3-alkoxy-1-alkyl-5-nitroindazoles.
Topics: Animals; Chagas Disease; Chlorocebus aethiops; Humans; Indazoles; Vero Cells | 2014 |
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.
Topics: Animals; Chagas Disease; Indazoles; Structure-Activity Relationship; Trichomonas; Trypanosoma cruzi | 2016 |
Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes.
Topics: Animals; Autophagy; Cell Membrane; Chagas Disease; Endoplasmic Reticulum; Flow Cytometry; Indazoles; Membrane Potential, Mitochondrial; Mice; Microscopy, Electron, Transmission; Mitochondria; Nitroimidazoles; Nuclear Envelope; Oxygen Consumption; Trypanocidal Agents; Trypanosoma cruzi | 2016 |
New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and mechanism of action studies.
Topics: Chagas Disease; Crystallography, X-Ray; DNA, Protozoan; HeLa Cells; Humans; Indazoles; Nitroimidazoles; Oxidation-Reduction; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2009 |
Research for new antichagasic drugs.
Topics: Animals; Azoles; Benzimidazoles; Chagas Disease; Imidazoles; Indazoles; Indoles; Mice; Nifurtimox; Nitro Compounds; Thiophenes; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 1991 |