Page last updated: 2024-08-21

indazoles and Cell Transformation, Neoplastic

indazoles has been researched along with Cell Transformation, Neoplastic in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Battistone, B; Garrido-Laguna, I; Ghazi, P; Kinsey, CG; McMahon, M; Parkman, GL; Scherzer, MT; Schuman, S; Truong, A; Vaishnavi, A1
Alessi, DR; Arbeiter, A; Baccarini, M; Dobler, M; Eser, S; Esposito, I; Gottschalk, K; Hieber, M; Kind, AJ; Klein, S; Kong, B; Messer, M; Michalski, CW; Rad, L; Rad, R; Reiff, N; Saur, D; Schlitter, AM; Schmid, RM; Schneider, G; Schnieke, AE; Seidler, B1
Beauchamp, EM; Getz, G; Gray, NS; Haddad, RI; Hammerman, PS; Hayes, DN; Jung, J; Liao, RG; Liu, Q; Meyerson, M; Pedamallu, CS; Pugh, TJ; Sivachenko, A; Tchaicha, J; Wilkerson, MD; Wong, KK1
Kazi, JU; Lindblad, O; Rönnstrand, L; Sun, J1
Haumann, R; Poot, AJ; Schuit, RC; Slobbe, P; van Dongen, GA; Windhorst, AD1
Altamura, S; Boueres, J; Ferrigno, F; Fonsi, M; Giomini, C; Jones, P; Lamartina, S; Monteagudo, E; Ontoria, JM; Orsale, MV; Palumbi, MC; Pesci, S; Roscilli, G; Rowley, M; Scarpelli, R; Schultz-Fademrecht, C; Toniatti, C1
Chen, C; Edin, ML; Gong, W; Li, Y; Liu, L; Wang, DW; Zeldin, DC1
Chun, YS; Park, JW; Yeo, EJ1
Benassi, M; Cametti, C; Castiglione, S; Floridi, A; Gentile, FP; Indovina, PL; Malorni, W; Santini, MT1

Reviews

1 review(s) available for indazoles and Cell Transformation, Neoplastic

ArticleYear
New anticancer strategies targeting HIF-1.
    Biochemical pharmacology, 2004, Sep-15, Volume: 68, Issue:6

    Topics: Adaptation, Physiological; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Targeting; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Neoplasms; Nuclear Proteins; Transcription Factors

2004

Other Studies

8 other study(ies) available for indazoles and Cell Transformation, Neoplastic

ArticleYear
Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer.
    Cell reports, 2020, 08-04, Volume: 32, Issue:5

    Topics: Animals; Apoptosis; Bcl-2-Like Protein 11; Benzamides; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; ErbB Receptors; Female; HEK293 Cells; Humans; Indazoles; Lung Neoplasms; Male; Mice, Inbred NOD; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Neoplasms; Pancreatic Neoplasms; Protein Kinase Inhibitors; Receptor, trkA

2020
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
    Cancer cell, 2013, Mar-18, Volume: 23, Issue:3

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Activation; Humans; Indazoles; Lithostathine; Metaplasia; Mice; Mice, Inbred NOD; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Signal Transduction; Sulfonamides; TNF Receptor-Associated Factor 3; Transplantation, Heterologous; Tumor Cells, Cultured

2013
Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma.
    Cancer research, 2013, Aug-15, Volume: 73, Issue:16

    Topics: Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dimerization; Humans; Indazoles; Interleukin-3; Ligands; Lung Neoplasms; Mice; Mice, Nude; Mutation; NIH 3T3 Cells; Protein Kinase Inhibitors; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Sulfonamides

2013
PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.
    Cellular and molecular life sciences : CMLS, 2015, Volume: 72, Issue:22

    Topics: Animals; Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Chromones; HEK293 Cells; Humans; Indazoles; Indoles; Morpholines; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-kit; Signal Transduction; src-Family Kinases; Stem Cell Factor; Sulfonamides

2015
Two anti-angiogenic TKI-PET tracers, [(11)C]axitinib and [(11)C]nintedanib: Radiosynthesis, in vivo metabolism and initial biodistribution studies in rodents.
    Nuclear medicine and biology, 2016, Volume: 43, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Axitinib; Carbon Radioisotopes; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Imidazoles; Indazoles; Indoles; Mice; Positron-Emission Tomography; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Radioactive Tracers; Radiochemistry; Rats; Tissue Distribution

2016
Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
    Journal of medicinal chemistry, 2009, Nov-26, Volume: 52, Issue:22

    Topics: Administration, Oral; Amides; Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Drug Discovery; Drug Stability; Enzyme Inhibitors; Female; Genes, BRCA1; Genes, BRCA2; Humans; Indazoles; Inhibitory Concentration 50; Mutation; Neoplasms; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Rats

2009
Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; HEK293 Cells; Humans; Indazoles; Membrane Potential, Mitochondrial; Mitochondria; Nitrofurans; Oxides; Reactive Oxygen Species

2011
Effects of lonidamine on the membrane electrical properties of Ehrlich ascites tumor cells.
    FEBS letters, 1991, Oct-21, Volume: 291, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Transformation, Neoplastic; Cytosol; Electric Conductivity; Indazoles; Male; Membrane Potentials; Mice; Suspensions; Tumor Cells, Cultured

1991