Page last updated: 2024-08-21

indazoles and Carcinoma

indazoles has been researched along with Carcinoma in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's3 (12.50)18.2507
2000's3 (12.50)29.6817
2010's12 (50.00)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Harada, H; Iwai, H; Kanda, A; Kawahara, A; Ohe, C; Sawada, S; Sengupta, B; Suzuki, K; Takeda, M; Uemura, Y1
Chandarana, SP; Ernst, MS; Hao, D; Hyrcza, MD; Lysack, JT1
Hoang, VH; Hue, NT; Lan, TH; Long, LTB; Minh, TC; Nguyen, TX; Nguyen, YTK; Tien, LQ; Tran, PT; Trang, NTK; Yoo, H1
Bianchetti, E; Canoll, P; Ishida, CT; Karpel-Massler, G; Kleiner, G; Nguyen, TTT; Quinzii, CM; Sanchez-Quintero, MJ; Shang, E; Shu, C; Siegelin, MD; Torrini, C; Westhoff, MA; Zhang, Y1
Alcoser, SY; Borgel, S; Bottaro, DP; Chen, AP; Chen, L; Chuaqui, R; Doroshow, JH; Ferry-Galow, KV; Hollingshead, MG; Kinders, RJ; Konaté, MM; Kummar, S; Lawrence, SM; Makhlouf, HR; Miller, SB; Navas, T; Parchment, RE; Rubinstein, L; Srivastava, AK; Subramanian, J; Vilimas, T; Voth, AR; Wilsker, DF1
Aishima, S; Kaneki, M; Kitajima, Y; Nakamura, J; Noshiro, H; Tanaka, T; Wakiyama, K; Yanagihara, K1
Abd Elmageed, ZY; Abdel-Mageed, AB; Kandil, E; Li, X; Ma, J; Mondal, D; Slakey, D; Tsumagari, K1
Bible, KC; Bossou, AR; Cradic, KW; Grebe, SK; Isham, CR; Milosevic, D; Netzel, BC1
Carlson, DM; Horai, T; Horiike, A; Horinouchi, H; Kaneda, H; McKee, MD; Nakagawa, K; Nishio, M; Nokihara, H; Ohyanagi, F; Okabe, T; Tamura, T; Terashima, M; Xiong, H; Yamamoto, N1
Carlson, JH; De, P; Dey, N; Leyland-Jones, B; Marcus, A; Wu, H1
Brabant, G; Burrows, N; Eustace, A; Fitzmaurice, RJ; Hoang-Vu, C; Irlam, J; Resch, J; Rowling, EJ; Telfer, BA; Valentine, HR; West, CM; Williams, J; Williams, KJ1
Chan, AT; Cheng, SH; Hong, B; Hui, EP; Leung, HS; Lu, Y; Lui, VW; Mills, GB; Ng, MH; Wong, EY1
Chowbay, B; Gao, F; Goh, BC; Ivy, P; Koh, TS; Leong, SS; Lim, WT; Ng, QS; Singh, O; Tan, DS; Tan, EH; Thng, CH; Toh, CK1
Barranger, E; Camus, M; Eveno, C; le Maignan, C; Pocard, M; Soyer, P1
Babur, M; Brabant, G; Burrows, N; Mejin, M; Resch, J; Ridsdale, S; Rowling, EJ; Williams, KJ1
Kim, W; Kim, YJ; Kwak, SW; Lee, CS; Lee, JJ; Lee, MS; Lee, SA; Myung, SC; Park, ES1
Cho, YS; Chun, YS; Kim, J; Kim, MS; Lee, JC; Park, JW; Yeo, EJ1
Berger, W; Heffeter, P; Jakupec, MA; Kapitza, S; Keppler, BK; Lackinger, L; Marian, B; Pongratz, M1
Sherman, SI1
Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, RA; Mermillod, B1
Bottalico, C; Brandi, M; Catino, A; De Lena, M; De Mitrio, A; Gargano, G; Guida, M; Latorre, A; Leone, B; Lorusso, V; Vallejo, C1
Berger, MR; Keppler, BK; Seelig, MH1
Gabriele, P; Ozzello, F; Sola, B; Tseroni, V1
Brann, TW; Frei, E; Holden, SA; Rosbe, KW; Teicher, BA1

Reviews

2 review(s) available for indazoles and Carcinoma

ArticleYear
Early clinical studies of novel therapies for thyroid cancers.
    Endocrinology and metabolism clinics of North America, 2008, Volume: 37, Issue:2

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Axitinib; Benzamides; Benzenesulfonates; Carcinoma; Clinical Trials as Topic; Drug Delivery Systems; Gefitinib; Humans; Imatinib Mesylate; Imidazoles; Indazoles; Indoles; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinazolines; Sorafenib; Thyroid Neoplasms

2008
New agents in non-small cell lung cancer.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Adult; Alkylating Agents; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Indazoles; Lung Neoplasms; Male; Mice; Mitoxantrone; Triazines; Vinblastine; Vindesine

1984

Trials

4 trial(s) available for indazoles and Carcinoma

ArticleYear
A phase 1 study of linifanib in combination with carboplatin/paclitaxel as first-line treatment of Japanese patients with advanced or metastatic non-small cell lung cancer (NSCLC).
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Non-Small-Cell Lung; Chemotherapy-Induced Febrile Neutropenia; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Indazoles; Japan; Leukopenia; Lung; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Phenylurea Compounds; Protein Kinase Inhibitors; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Severity of Illness Index; Thrombocytopenia; Tumor Burden

2014
A Phase II study of pazopanib in Asian patients with recurrent/metastatic nasopharyngeal carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16

    Topics: Adult; Aged; Angiogenesis Inhibitors; Anorexia; Asian People; Carcinoma; Diarrhea; Drug Administration Schedule; Fatigue; Female; Humans; Indazoles; Kaplan-Meier Estimate; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Pyrimidines; Sulfonamides; Treatment Outcome; Vomiting

2011
New agents in non-small cell lung cancer.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Adult; Alkylating Agents; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Indazoles; Lung Neoplasms; Male; Mice; Mitoxantrone; Triazines; Vinblastine; Vindesine

1984
Revertant and potentiating activity of lonidamine in patients with ovarian cancer previously treated with platinum.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Cisplatin; Drug Synergism; Female; Humans; Indazoles; Middle Aged; Ovarian Neoplasms

1997

Other Studies

19 other study(ies) available for indazoles and Carcinoma

ArticleYear
Clinicopathological investigation of secretory carcinoma cases including a successful treatment outcome using entrectinib for high-grade transformation: a case report.
    BMC medical genomics, 2022, 01-06, Volume: 15, Issue:1

    Topics: Benzamides; Biomarkers, Tumor; Carcinoma; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Indazoles; Neoplasm Recurrence, Local; Oncogene Proteins, Fusion; Salivary Gland Neoplasms; Treatment Outcome

2022
TRK Inhibition with Entrectinib in Metastatic Salivary Secretory Carcinoma (SC): A Case Report.
    Current oncology (Toronto, Ont.), 2022, 05-31, Volume: 29, Issue:6

    Topics: Benzamides; Breast Neoplasms; Carcinoma; Gene Fusion; Humans; Indazoles

2022
Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents.
    Bioorganic & medicinal chemistry, 2023, 07-15, Volume: 90

    Topics: Antineoplastic Agents; Carcinoma; Enzyme Inhibitors; Humans; Indazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Tryptophan

2023
Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition.
    EMBO molecular medicine, 2019, Volume: 11, Issue:10

    Topics: Animals; Apoptosis; bcl-X Protein; Benzoates; Benzylamines; Carcinoma; Cell Proliferation; Cell Respiration; Disease Models, Animal; Gene Expression Profiling; Glioblastoma; Humans; Indazoles; Liver X Receptors; Melanoma; Metabolomics; Models, Theoretical; Treatment Outcome

2019
Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas.
    Cancer research, 2020, 01-15, Volume: 80, Issue:2

    Topics: Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; beta Catenin; Biomarkers, Tumor; Biopsy, Large-Core Needle; Cadherins; Carcinoma; Cell Line, Tumor; Cell Plasticity; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Humans; Indazoles; Male; Mice; Neoplastic Stem Cells; Paclitaxel; Pyrimidines; Sulfonamides; Vimentin; Xenograft Model Antitumor Assays

2020
Low-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis.
    Scientific reports, 2017, 10-04, Volume: 7, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetyl Coenzyme A; Anaerobiosis; Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Deoxyguanosine; Glucose; Glucose Transporter Type 1; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Insulin; Mice; Nitroimidazoles; Oxidative Phosphorylation; Stomach Neoplasms; Tumor Hypoxia; Xenograft Model Antitumor Assays

2017
Synergistic inhibition of thyroid cancer by suppressing MAPK/PI3K/AKT pathways.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Carcinoma; Carcinoma, Papillary; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indazoles; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides; Thyroid Cancer, Papillary; Thyroid Neoplasms

2013
Development and characterization of a differentiated thyroid cancer cell line resistant to VEGFR-targeted kinase inhibitors.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:6

    Topics: Animals; Carcinoma; Carcinoma, Papillary; Cell Culture Techniques; Cell Line, Tumor; DNA Mutational Analysis; Drug Resistance, Neoplasm; Humans; Indazoles; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Pyrimidines; ras Proteins; Receptors, Vascular Endothelial Growth Factor; Sulfonamides; Thyroid Cancer, Papillary; Thyroid Neoplasms; Xenograft Model Antitumor Assays

2014
Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Adenomatous Polyposis Coli Protein; beta Catenin; Brain Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dishevelled Proteins; Female; Fibronectins; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Humans; Indazoles; Integrins; Matrix Metalloproteinase 7; Microscopy, Confocal; Microscopy, Fluorescence; Microscopy, Video; Mutation; Phenotype; RNA Interference; RNA, Small Interfering; Sulfonamides; Sulindac; Triple Negative Breast Neoplasms; Up-Regulation; Wnt Proteins; Wnt Signaling Pathway

2016
Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas.
    Oncotarget, 2016, Sep-27, Volume: 7, Issue:39

    Topics: Animals; Carcinoma; Carcinoma, Papillary; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Enzyme Activation; Female; Histones; Humans; Hypoxia; Indazoles; Mice; Mice, Nude; Neoplasm Transplantation; Oxygen; Phosphatidylinositol 3-Kinases; Radiation Tolerance; Signal Transduction; Sulfonamides; Thyroid Cancer, Papillary; Thyroid Neoplasms

2016
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.
    Biochemical pharmacology, 2010, Mar-15, Volume: 79, Issue:6

    Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Down-Regulation; Furans; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Protein Array Analysis; Protein Kinases; Protein Serine-Threonine Kinases; S Phase

2010
Late anastomotic colonic dehiscence due to antiangiogenic treatment, a specific drug-class complication requiring specific treatment: an example of pazopanib complication.
    Clinics and research in hepatology and gastroenterology, 2011, Volume: 35, Issue:2

    Topics: Anastomosis, Surgical; Angiogenesis Inhibitors; Anti-Bacterial Agents; Carcinoma; Colectomy; Female; Humans; Hysterectomy; Indazoles; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Ovarian Neoplasms; Ovariectomy; Peritoneal Neoplasms; Pyrimidines; Salpingectomy; Sulfonamides; Surgical Wound Dehiscence; Treatment Outcome

2011
GDC-0941 inhibits metastatic characteristics of thyroid carcinomas by targeting both the phosphoinositide-3 kinase (PI3K) and hypoxia-inducible factor-1α (HIF-1α) pathways.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:12

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Hypoxia; Cell Movement; Cell Proliferation; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mice; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; Signal Transduction; Sulfonamides; Thyroid Neoplasms; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2011
Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways.
    European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Carcinoma, Ovarian Epithelial; Caspases; Cell Line, Tumor; Cell Nucleus; Chalcones; Drug Interactions; Enzyme Activation; Female; Guanylate Cyclase; Humans; Indazoles; Neoplasm Proteins; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteolysis; Signal Transduction; Tumor Suppressor Protein p53

2012
YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.
    Journal of the National Cancer Institute, 2003, Apr-02, Volume: 95, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Hepatocellular; Cell Hypoxia; Culture Media, Conditioned; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Female; G(M1) Ganglioside; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Indazoles; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Killer Cells, Natural; Liver Neoplasms; Lymphokines; Male; Mice; Mice, SCID; Neoplasms; Neovascularization, Pathologic; Neuroblastoma; Platelet Endothelial Cell Adhesion Molecule-1; Precipitin Tests; Rats; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription Factors; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:2

    Topics: Apoptosis; Carcinoma; Colorectal Neoplasms; Humans; Indazoles; Mitochondria; Organometallic Compounds; Ruthenium; Salts; Tumor Cells, Cultured

2005
Antineoplastic activity of three ruthenium derivatives against chemically induced colorectal carcinoma in rats.
    Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:3

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma; Colorectal Neoplasms; Dose-Response Relationship, Drug; Imidazoles; Indazoles; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Ruthenium

1992
[A case of acinic cell carcinoma of the parotid gland treated with radiotherapy combined with hyperthermia and Doridamine].
    La Radiologia medica, 1990, Volume: 80, Issue:5

    Topics: Adult; Carcinoma; Combined Modality Therapy; Female; Humans; Hyperthermia, Induced; Indazoles; Parotid Neoplasms

1990
Effect of lonidamine on the cytotoxicity of four alkylating agents in vitro.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:1

    Topics: Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Indazoles; Pyrazoles; Time Factors; Tumor Cells, Cultured

1989