Compounds > indazoles
Page last updated: 2024-08-21

indazoles and Cancer of Head

indazoles has been researched along with Cancer of Head in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's3 (14.29)18.2507
2000's1 (4.76)29.6817
2010's13 (61.90)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Kleszcz, R; Paluszczak, J1
Bridges, KA; Clump, DA; Faust, AZ; Ferris, RL; Frederick, MJ; Heffernan, TP; Mason, KA; Meyn, RE; Molkentine, DP; Molkentine, JM; Myers, JN; Pickering, CR; Sheth, A; Skinner, HD; Xie, T; Yang, L1
Cao, J; Chen, M; Frank, SJ; Jiang, B; Li, Y; Lin, E; Myers, JN; Sahoo, N; Wang, L; Wang, X; Wang, Z; Zhang, R; Zhang, X; Zhu, XR1
Brands, RC; De Donno, F; Hartmann, S; Knierim, LM; Kübler, AC; Müller-Richter, UDA; Seher, A; Steinacker, V1
Chen, CS; de Necochea-Campion, R; Ferris, RL; Gridley, DS; Hsu, HW; Hu, S; Kim, PD; Mirshahidi, S1
Abe, K; Asai, M; Koike, Y; Ogawa, F; Tanioka, M; Tomita, H; Utani, A1
Chen, CS; de Necochea-Campion, R; Duerksen-Hughes, PJ; Ferris, RL; Hsu, HW; Mirshahidi, S; Simental, AA; Williams, V1
Bonner, JA; Buchsbaum, DJ; Grizzle, WE; Li, Y; Meredith, RF; Raisch, KP; Spencer, SA1
Haga, N; Hata, H; Homma, E; Imafuku, K; Kitamura, S; Shimizu, H1
Hoshino, D; Maldonado, AT; Tyson, DR; Weaver, AM; Wirtz, ED1
Belile, E; Bradford, C; Carey, T; Chepeha, DB; Dobrosotskaya, I; Eisbruch, A; Malloy, K; McKean, E; McLean, S; Moyer, J; Prince, M; Sacco, AG; Shuman, A; Spector, M; Swiecicki, PL; Wolf, GT; Worden, FP; Zhao, L1
Spector, M; Swiecicki, PL; Worden, FP1
Demizu, Y; Futani, H; Mohri, T; Okimoto, T; Sakagami, M; Terada, T; Tsukamoto, Y; Uwa, N1
Hirabayashi, M; Hoashi, T; Nakajima, R; Saeki, H; Takahashi, N1
Ben-Jonathan, N; Kumar, B; Kumar, P; Takiar, V; Tuttle, TR1
Baek, WK; Jang, BC; Kwon, TK; Lee, J; Lee, SR; Park, JW; Park, SH; Shin, HC; Song, DW1
Duce, SL; García-Martínez, JM; Wullschleger, S1
Ciottoli, GB; Magno, L; Terraneo, F1
Angelini, F; Ausili Cefaro, GP; Blengio, F; Cirulli, S; Cognetti, F; Colella, E; Giannarelli, D; Lo Russo, V; Merlano, M; Scasso, F1
Bardelli, D; Bertoni, F; Ciottoli, GB; Magno, L; Rosignoli, MT; Terraneo, F; Tordiglione, M1
DeGregorio, M; Newton, RE; Paggiarino, DA; Scarantino, CW1

Reviews

2 review(s) available for indazoles and Cancer of Head

ArticleYear
Axitinib in the Treatment of Head and Neck Malignancies.
    Current clinical pharmacology, 2016, Volume: 11, Issue:2

    Topics: Axitinib; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Imidazoles; Indazoles; Molecular Targeted Therapy; Protein Kinase Inhibitors; Receptors, Vascular Endothelial Growth Factor; Squamous Cell Carcinoma of Head and Neck; Survival; Thyroid Neoplasms

2016
Lonidamine in head and neck cancer: an overview.
    Seminars in oncology, 1991, Volume: 18, Issue:2 Suppl 4

    Topics: Antineoplastic Agents; Head and Neck Neoplasms; Humans; Indazoles

1991

Trials

3 trial(s) available for indazoles and Cancer of Head

ArticleYear
A phase II study evaluating axitinib in patients with unresectable, recurrent or metastatic head and neck cancer.
    Investigational new drugs, 2015, Volume: 33, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Axitinib; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypertension; Imidazoles; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Survival Rate

2015
Randomised phase II study of methotrexate (MTX) versus methotrexate plus lonidamine (MTX + LND) in recurrent and/or metastatic carcinoma of the head and neck.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Indazoles; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local

1994
Double-blind randomized study of lonidamine and radiotherapy in head and neck cancer.
    International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1

    Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Indazoles; Lymphatic Metastasis; Male; Middle Aged; Radiotherapy Dosage; Survival Analysis; Time Factors

1994

Other Studies

16 other study(ies) available for indazoles and Cancer of Head

ArticleYear
The Wnt Signaling Pathway Inhibitors Improve the Therapeutic Activity of Glycolysis Modulators against Tongue Cancer Cells.
    International journal of molecular sciences, 2022, Jan-23, Volume: 23, Issue:3

    Topics: Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Line, Tumor; Cell Survival; Deoxyglucose; Glucose; Glycolysis; Head and Neck Neoplasms; Humans; Indazoles; Pyrimidinones; Tongue; Tongue Neoplasms; Wnt Signaling Pathway

2022
Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints.
    International journal of radiation biology, 2021, Volume: 97, Issue:8

    Topics: Cell Cycle Checkpoints; Cell Line, Tumor; DNA Damage; Head and Neck Neoplasms; Humans; Indazoles; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Pyrazoles; Pyrimidinones; Radiation Tolerance

2021
Proton and photon radiosensitization effects of niraparib, a PARP-1/-2 inhibitor, on human head and neck cancer cells.
    Head & neck, 2020, Volume: 42, Issue:9

    Topics: Cell Line, Tumor; Head and Neck Neoplasms; Humans; Indazoles; Photons; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Protons; Radiation-Sensitizing Agents

2020
Targeting VEGFR and FGFR in head and neck squamous cell carcinoma in vitro.
    Oncology reports, 2017, Volume: 38, Issue:3

    Topics: Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Head and Neck Neoplasms; Humans; Indazoles; Indoles; Male; Protein Kinase Inhibitors; Pyrimidines; Quinolones; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Sulfonamides

2017
Linifanib (ABT-869) enhances radiosensitivity of head and neck squamous cell carcinoma cells.
    Oral oncology, 2013, Volume: 49, Issue:6

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Head and Neck Neoplasms; Humans; Indazoles; Phenylurea Compounds; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; STAT3 Transcription Factor

2013
Angiosarcoma of the scalp successfully treated with pazopanib.
    Journal of the American Academy of Dermatology, 2014, Volume: 70, Issue:1

    Topics: Angiogenesis Inhibitors; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Indazoles; Male; Middle Aged; Pyrimidines; Scalp; Skin Neoplasms; Sulfonamides

2014
Linifanib (ABT-869), enhances cytotoxicity with poly (ADP-ribose) polymerase inhibitor, veliparib (ABT-888), in head and neck carcinoma cells.
    Oral oncology, 2014, Volume: 50, Issue:7

    Topics: Apoptosis; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Breaks; Head and Neck Neoplasms; Histones; Humans; Indazoles; Phenylurea Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rad51 Recombinase

2014
Pazopanib combined with radiation: in vivo model of interaction.
    Cancer biotherapy & radiopharmaceuticals, 2014, Volume: 29, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Indazoles; Lung Neoplasms; Mice; Mice, Nude; Pyrimidines; Sulfonamides; Xenograft Model Antitumor Assays

2014
Pazopanib can preserve cosmetic quality of life even in end-stage angiosarcoma.
    Clinical and experimental dermatology, 2015, Volume: 40, Issue:8

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Female; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Indazoles; Protein Kinase Inhibitors; Pyrimidines; Quality of Life; Scalp; Skin Neoplasms; Sulfonamides

2015
Response of head and neck squamous cell carcinoma cells carrying PIK3CA mutations to selected targeted therapies.
    JAMA otolaryngology-- head & neck surgery, 2015, Volume: 141, Issue:6

    Topics: Benzoquinones; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Head and Neck Neoplasms; Humans; Imidazoles; Indazoles; Inhibitory Concentration 50; Lactams, Macrocyclic; Molecular Targeted Therapy; Mutation; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Pyridones; Pyrimidinones; Quinolines; Squamous Cell Carcinoma of Head and Neck; Sulfonamides; TOR Serine-Threonine Kinases; Tumor Cells, Cultured

2015
An unexpected skin ulcer and soft tissue necrosis after the nonconcurrent combination of proton beam therapy and pazopanib: A case of myxofibrosarcoma.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:4

    Topics: Angiogenesis Inhibitors; Debridement; Fatal Outcome; Fibrosarcoma; Head and Neck Neoplasms; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Myxoma; Necrosis; Proton Therapy; Pyrimidines; Skin Ulcer; Soft Tissue Infections; Sulfonamides; Tomography, X-Ray Computed

2017
Paradoxical antitumor effects of pazopanib in a cutaneous angiosarcoma patient.
    The Journal of dermatology, 2017, Volume: 44, Issue:9

    Topics: Aged; Angiogenesis Inhibitors; Disease Progression; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Indazoles; Male; Pyrimidines; Skin Neoplasms; Sulfonamides

2017
Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells.
    Cancer letters, 2017, 03-28, Volume: 389

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; beta Catenin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; ErbB Receptors; Head and Neck Neoplasms; Humans; Indazoles; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Pyridines; Soluble Guanylyl Cyclase; Squamous Cell Carcinoma of Head and Neck

2017
Anticancer activity and differentially expressed genes in head and neck cancer cells treated with a novel cyclin-dependent kinase inhibitor.
    Chemotherapy, 2009, Volume: 55, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cyclin-Dependent Kinases; Cytochromes c; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Head and Neck Neoplasms; Humans; Indazoles; Protein Kinase Inhibitors; Thiazolidines; Type C Phospholipases

2009
Quantitative MRI establishes the efficacy of PI3K inhibitor (GDC-0941) multi-treatments in PTEN-deficient mice lymphoma.
    Anticancer research, 2012, Volume: 32, Issue:2

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Indazoles; Longitudinal Studies; Lymphoma, B-Cell; Lymphoma, Follicular; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Sulfonamides

2012
Lonidamine and radiotherapy in head and neck cancers. A pilot study.
    Oncology, 1984, Volume: 41 Suppl 1

    Topics: Antineoplastic Agents; Female; Head and Neck Neoplasms; Humans; Indazoles; Male; Pyrazoles; Radiation-Sensitizing Agents

1984