indazoles has been researched along with Cancer of Colon in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Berdini, V; Boulstridge, JA; Carr, MG; Cross, DM; Davis, DJ; Devine, LA; Early, TR; Feltell, RE; Lewis, EJ; McMenamin, RL; Navarro, EF; O'Brien, MA; O'Reilly, M; Reule, M; Saxty, G; Seavers, LC; Smith, DM; Squires, MS; Trewartha, G; Walker, MT; Woodhead, AJ; Woolford, AJ; Wyatt, PG | 1 |
| Bartlett, DL; Choudry, HA; Dilly, A; Honick, BD; Lee, YJ | 1 |
| Dueñas-Gonzalez, A; Schcolnik-Cabrera, A | 1 |
| Chavez-Blanco, A; Diaz-Chavez, J; Dominguez-Gomez, G; Duenas-Gonzalez, A; Hua, S; Juarez, M; Lai, D; Perez-Montiel, D; Ponce-Toledo, RI; Schcolnik-Cabrera, A; Torres, N; Tovar, AR; Vargas-Castillo, A | 1 |
| Brown, B; Molloy, MP; Neilson, KA; Semaan, C | 1 |
| Huang, J; Huang, S; Li, QJ; Long, H; Symonds, ALJ; Tang, X; Wan, YY; Wang, Z; Xu, L; Zhou, J; Zhu, B | 1 |
| Chard, RA; Jang, T; Walsby, CJ; Webb, MI; Wong, EW; Wong, MQ; Wu, B; Yapp, DT | 1 |
| Awrey, DE; Ban, F; Beletskaya, I; Bray, MR; Che, Y; Chirgadze, NY; Edwards, L; Feher, M; Fletcher, GC; Forrest, B; Hodgson, R; Kiarash, R; Lang, Y; Laufer, R; Li, SW; Lin, DC; Liu, Y; Madeira, B; Mak, TW; Mao, G; Mason, JM; Ng, G; Patel, NK; Pauls, HW; Plotnikova, O; Qiu, W; Sampson, PB; Wei, X | 1 |
| Atreya, CE; Bergsland, EK; Cives, M; Coppola, D; Hwang, J; Kelley, RK; Morse, B; Nickerson, M; Strosberg, JR; Valone, T; Venook, A; Weber, T | 1 |
| Huang, X; Li, W; Tan, Z; Wang, H; Wang, J; Yu, R; Zhang, L; Zhang, Y; Zhong, J | 1 |
| Chae, HJ; Kim, HR; Lee, GH | 1 |
| He, B; Xie, F; Zhao, J; Zhao, T | 1 |
| Auffray, C; Candeil, L; Copois, V; Crabbé, L; Del Rio, M; Gourdier, I; Martineau, P; Mechti, N; Pau, B; Pommier, Y; Ychou, M | 1 |
| Bogdanov, AA; Figueiredo, J; Hu-Lowe, D; Kang, HW; Kim, YR; Mahmood, U; Petrovsky, A; Reichardt, W; Torres, D; Weissleder, R; Yudina, A | 1 |
| Ahnen, DJ; Beard, KS; Peters, SL; Rice, PL | 1 |
| Fuchs, AG | 1 |
| Codacci Pisanelli, G; Franchi, F; Giovagnorio, F; Gualdi, G; Guazzugli Bonaiuti, VP; Seminara, P | 1 |
| Bearzatto, A; Costa, A; Orlandi, L; Silvestrini, R; Villa, R; Zaffaroni, N | 1 |
| Beggiolin, G; Di Domenico, R; Fiocchi, L; Gallagher, CE; Giuliani, FC; Hacker, MP; Krapcho, AP; Maresch, ME; Menta, E; Oliva, A; Pezzoni, G; Spinelli, S | 1 |
| Bruno, T; Di Padova, M; Fanciulli, M; Floridi, A; Gentile, FP; Giovannelli, A; Rubiu, O | 1 |
| Kaplan, O | 1 |
1 trial(s) available for indazoles and Cancer of Colon
| Article | Year |
|---|---|
A phase II study of axitinib in advanced neuroendocrine tumors.
Topics: Adult; Aged; Antineoplastic Agents; Axitinib; Colonic Neoplasms; Female; Humans; Hypertension; Imidazoles; Indazoles; Intestinal Neoplasms; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Protein Kinase Inhibitors; Rectal Neoplasms; Thymus Neoplasms; Treatment Outcome | 2016 |
20 other study(ies) available for indazoles and Cancer of Colon
| Article | Year |
|---|---|
Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Drug Design; Enzyme Inhibitors; Humans; Mice; Piperidines; Pyrazoles; Structure-Activity Relationship | 2008 |
Rational application of targeted therapeutics in mucinous colon/appendix cancers with positive predictive factors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Appendix; Cell Line, Tumor; Chemotherapy, Adjuvant; Colon; Colonic Neoplasms; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Female; Humans; Indazoles; Intestinal Mucosa; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Targeted Therapy; Mucin-2; Mutation; Neoplasms, Cystic, Mucinous, and Serous; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidinones; Sulfonamides; Xenograft Model Antitumor Assays | 2020 |
Mouse Model for Efficient Simultaneous Targeting of Glycolysis, Glutaminolysis, and De Novo Synthesis of Fatty Acids in Colon Cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Diazooxonorleucine; Drug Screening Assays, Antitumor; Fatty Acid Synthase, Type I; Fatty Acids; Female; Glutaminase; Glutamine; Glycolysis; Hexokinase; Indazoles; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Orlistat; Smegmamorpha | 2021 |
Pharmacological inhibition of tumor anabolism and host catabolism as a cancer therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Daunorubicin; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glycolysis; Growth Hormone; Humans; Indazoles; Indomethacin; Insulin; Metabolic Networks and Pathways; Metabolism; Mice; Mitoxantrone; Orlistat; Oxidative Phosphorylation; Vincristine | 2021 |
Pharmacological Inhibition of Casein Kinase 2 Enhances the Effectiveness of PI3K Inhibition in Colon Cancer Cells.
Topics: Casein Kinase II; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Imidazoles; Indazoles; MAP Kinase Signaling System; Mutation; Naphthyridines; Oximes; Phenazines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins B-raf; Sulfonamides | 2018 |
Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation.
Topics: Animals; Cell Differentiation; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Female; Hematopoietic Stem Cells; Histone Code; Histones; In Vitro Techniques; Indazoles; Indoles; Inflammatory Bowel Diseases; Methylation; Mice; Myeloid-Derived Suppressor Cells; Pyridones | 2019 |
Increasing the bioavailability of Ru(III) anticancer complexes through hydrophobic albumin interactions.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Humans; Hydrophobic and Hydrophilic Interactions; Indazoles; Ligands; Molecular Structure; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Serum Albumin | 2013 |
The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as Anticancer Agents.
Topics: Administration, Oral; Animals; Cell Cycle Proteins; Cell Line, Tumor; Colon; Colonic Neoplasms; Crystallography, X-Ray; Female; Humans; Indazoles; Mice, Nude; Models, Molecular; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 2015 |
Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Mice; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Signal Transduction; Sulfonamides; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2017 |
Monoamine carboxylate transporters are involved in BI-1-associated cancer metastasis in HT1080 colon fibrosarcoma cells.
Topics: Apoptosis Regulatory Proteins; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Extracellular Space; Fibrosarcoma; Gene Expression; Homeostasis; Humans; Hydrogen-Ion Concentration; Indazoles; Membrane Proteins; Neoplasm Metastasis; Sodium-Hydrogen Exchangers; Vesicular Monoamine Transport Proteins | 2011 |
[Therapeutic effect of axitinib and 5-FU in nude mice bearing human colon cancer xenograft].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Cell Line, Tumor; Colonic Neoplasms; Female; Fluorouracil; Humans; Imidazoles; Indazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays | 2012 |
Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Base Sequence; Blotting, Western; Caspase 3; Caspases; Colonic Neoplasms; DNA Primers; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Indazoles; Models, Biological; Organoplatinum Compounds; Oxaliplatin; Oxides; Proto-Oncogene Proteins c-bcl-2 | 2002 |
Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Colonic Neoplasms; Erythrocyte Volume; Humans; Indazoles; Magnetic Resonance Angiography; Mice; Mice, Nude; Neovascularization, Pathologic; Phosphorylation; Protein Kinase Inhibitors; Radionuclide Imaging; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2005 |
Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Butadienes; Colonic Neoplasms; Cyclic GMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Enzyme Activators; Humans; Indazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Sulindac; Tumor Cells, Cultured | 2006 |
[Treatment and post-treatment with lonidamine in human colon carcinoma HT-29 cell line].
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Hexokinase; HT29 Cells; Humans; Indazoles; Mitochondria | 2008 |
Elevated doses of carmustine and mitomycin C, with lonidamine enhancement and autologous bone marrow transplantation in the treatment of advanced colorectal cancer: results from a pilot study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Indazoles; Male; Middle Aged; Mitomycin; Pilot Projects; Rectal Neoplasms; Survival Analysis | 1994 |
In vitro effect of lonidamine on the cytotoxicity of mitomycin C and BCNU in human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cell Cycle; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Indazoles; Mitomycin; Tumor Cells, Cultured | 1994 |
Synthesis and antitumor evaluation of 2,5-disubstituted-indazolo[4, 3-gh]isoquinolin-6(2H)-ones (9-aza-anthrapyrazoles).
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Indazoles; Inhibitory Concentration 50; Isoquinolines; Leukemia P388; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured | 1998 |
Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence of lonidamine.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Carbon Dioxide; Cell Division; Citrate (si)-Synthase; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Energy Metabolism; Glucose; Hexokinase; Humans; Indazoles; Inhibitory Concentration 50; Isocitrate Dehydrogenase; Kinetics; Lactic Acid; Tumor Cells, Cultured | 2000 |
Correspondence re: M. Fanciulli et al., Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence fo lonidamine. Clin. Cancer Res., 6: 1590-1597, 2000.
Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Neoplasm; Glycolysis; Hexokinase; Humans; Indazoles; Lactic Acid; Tumor Cells, Cultured | 2000 |