Compounds > indazoles
Page last updated: 2024-08-21

indazoles and Bone Cancer

indazoles has been researched along with Bone Cancer in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.88)18.2507
2000's3 (7.32)29.6817
2010's26 (63.41)24.3611
2020's10 (24.39)2.80

Authors

AuthorsStudies
Bohrer, J; Damle, R; Driscoll, J; Fiorella, A; Hawkins, R; Mamidi, RNVS; Manning, CD; Packman, K; Patel, S; Snyder, LA; Stratton, CF; Tatikola, K; Tryputsen, V1
Dai, L; Li, A; Li, X; Liu, W; Liu, Z; Qin, S; Wang, P; Xiong, X; Zhang, J; Zhang, Z1
Albersen, M; Baldewijns, M; Beuselinck, B; Bourgain, C; Debruyne, PR; Haaker, L; Laenen, A; Laguerre, B; Lerut, E; Oudard, S; Renders, I; Rioux-Leclercq, N; Roussel, E; Tryssesoone, L; Van den Bulck, H; Verbiest, A; Wynendaele, W1
Chen, L; Cheng, S; Li, B; Lin, Z; Wang, M; Wang, W; Yao, M; Yin, Q; Zhang, Y1
Beck, JF; Becker, S; Kerschner-Morales, SL; Kühne, M; Sonnemann, J1
Bach, S; Baratte, B; Ben Salah, S; Berteina-Raboin, S; Bescond, A; Bonnet, P; Buron, F; Carles, F; Chaikuad, A; Chartier, A; Desban, N; Duez, J; Elie, J; Fant, X; Feizbakhsh, O; Josselin, B; Knapp, S; Marie, D; Place, M; Routier, S; Ruchaud, S1
Du, C; He, G; Liu, X; Ma, Y; Mao, C; Pan, X; Zhu, Y1
Abdelhamid, AH; Agarwal, S; Bobbili, PJ; Chugh, R; Demetri, GD; Duh, MS; Gounder, MM; Huynh, L; Lax, AK; Merriam, P; Patel, SR; Rajarethinam, A; Ratan, R; Thornton, M; Totev, TI; Van Tine, BA; Villalobos, VM; Whalen, J; Yang, J1
Higuchi, T; Hoffman, RM; Kanaya, F; Miyake, K; Nishida, K; Oshiro, H; Sugisawa, N; Tome, Y1
Adachi, S; Kato, I; Okamoto, T; Saida, S; Umeda, K1
Davidson, D; Jones, RL; Katz, D; Loggers, ET; Pollack, SM; Rodler, ET1
Gao, C; Gao, H; Liu, S; Liu, W; Xing, D1
Iida, S; Joh, T; Kanamori, T; Kataoka, H; Kinoshita, S; Komatsu, H; Kondo, M; Kuroda, J; Mori, Y; Takemoto, M1
Basso, U; Bearz, A; Berruti, A; Bracarda, S; Buti, S; Cartenì, G; Caserta, C; Cognetti, F; Cortesi, E; De Giorgi, U; Fornarini, G; Galli, L; Giannarelli, D; Lo Re, G; Pignata, S; Porta, C; Procopio, G; Rastelli, F; Sabbatini, R; Sternberg, CN; Turci, D1
Adachi, A; Komine, M; Maekawa, T; Murata, S; Ohtsuki, M1
Abate, ME; Boye, K; Cesari, M; Donati, D; Hompland, I; Longhi, A; Paioli, A; Palmerini, E; Setola, E; Spinnato, P1
Akers, LJ; Albritton, KH; Basha, R; Elete, KR; Ray, A1
Bae, WK; Byun, SS; Chung, HS; Chung, J; Hong, SH; Hwang, EC; Hwang, JE; Jeong, CW; Jung, SI; Kim, MS; Kwak, C; Kwon, DD; Park, JY; Seo, SI; Song, C1
Hayashi, K; Igarashi, K; Miwa, S; Takeuchi, A; Tsuchiya, H; Yamamoto, N1
Omrčen, T; Rini, B; Schmidinger, M; Sella, A; Szczylik, C; Torday, L; Vrdoljak, E1
Agerbaek, M; Donskov, F; Fode, K; Folkmar, TB; Smidt-Hansen, T1
Choueiri, TK; Heng, DY; Lin, X; McKay, RR; Perkins, JJ; Simantov, R1
Boysen, A; Lücke, A; Rossen, P; Safwat, A1
Affolter, T; Christensen, J; Eisele, K; Eswaraka, J; Feng, Z; Giddabasappa, A; Han, G; Lalwani, K; Li, G1
Alcindor, T1
Kawai, A; Kawashima, M; Kobayashi, E; Kobayashi, K; Koyama, T; Setsu, N1
Bhatt, K; Kattan, MW; McCann, L; Mehmud, F; Motzer, RJ; Sternberg, CN1
Honda, A; Kawano, H; Kogure, Y; Kume, H; Kurokawa, M; Nannya, Y; Shinoda, Y; Toya, T; Ushiku, T; Yamashita, H; Yoshimi, A1
Izumi, K; Konaka, H; Mizokami, A; Namiki, M; Yaegashi, H1
Bertino, E; Haglund, K; Haraldsdottir, S; Kaffenberger, B; Shah, MH1
Grünwald, V; Kalanovic, D; Lin, X; Simantov, R1
Cao, W; Dai, L; Liang, W; Liu, Z; Qin, S; Xiong, X; Ye, D; Zhang, J1
Ali, SM; Amini, B; Elvin, JA; Erlich, RL; Gowen, K; Holmes, O; Meric-Bernstam, F; Miller, V; Piha-Paul, S; Ross, JS; Schrock, AB; Spritz, D; Stephens, PJ; Stockman, DL; Subbiah, V; Suh, JH; Vergilio, JA; Wang, WL; Zarzour, M; Zinner, R1
Banfor, PN; Bayburt, E; Chandran, P; Daanen, JF; Faltynek, CR; Fryer, RM; Gauvin, DM; Ghilardi, JR; Gomtsyan, A; Hernandez, G; Honore, P; Jarvis, MF; Joshi, SK; Kort, ME; Kym, PR; Lee, CH; Mantyh, PW; Marsh, K; Mikusa, JP; Neelands, T; Reilly, RM; Segreti, JA; Sevcik, MA; Sullivan, JP; Surowy, CS; Zhong, C1
Barrios, CH; Chen, M; Davis, ID; Gladkov, OA; Hawkins, RE; Kavina, A; Lee, E; Mardiak, J; McCann, L; Pandite, L; Roychowdhury, DF; Salman, P; Sternberg, CN; Szczylik, C; Wagstaff, J; Zarbá, JJ1
Denny, CT; Federman, N; Glaser, KB; Ikeda, AK; Judelson, DR; Landaw, EM; Sakamoto, KM1
Araki, N; Itoh, K; Naka, N; Tanaka, T; Wakamatsu, T; Yoshikawa, H; Yoshioka, K; Yui, Y1
Hiraga, T; Hiraoka, M; Hirota, K; Kizaka-Kondoh, S; Yoneda, T1
Bolte, O; Bukowski, RM; Bycott, P; Freddo, J; Hudes, GR; Kim, S; Liau, KF; Michaelson, MD; Motzer, RJ; Rini, BI; Rixe, O; Trask, PC; Wilding, G1
Bonewald, LF; Chen, D; Gallwitz, W; Garcia, C; Kirchen, M; Mundy, GR; Qiao, M1
Hunter, RD; Logue, JP; Magee, B; Murdoch, RD1

Reviews

2 review(s) available for indazoles and Bone Cancer

ArticleYear
Therapeutic Targets for Bone and Soft-Tissue Sarcomas.
    International journal of molecular sciences, 2019, Jan-04, Volume: 20, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bone Neoplasms; Drug Therapy; Furans; Humans; Immunotherapy, Adoptive; Indazoles; Ipilimumab; Ketones; Nivolumab; Osteosarcoma; Progression-Free Survival; Pyrimidines; Sarcoma; Soft Tissue Neoplasms; Sorafenib; Sulfonamides; Trabectedin

2019
Bisphosphonates and vascular endothelial growth factor-targeted drugs in the treatment of patients with renal cell carcinoma metastatic to bone.
    Anti-cancer drugs, 2013, Volume: 24, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Humans; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Sunitinib; Vascular Endothelial Growth Factor A; Zoledronic Acid

2013

Trials

5 trial(s) available for indazoles and Bone Cancer

ArticleYear
Development and Validation of a Prognostic Nomogram for Progression-Free Survival in Patients with Advanced Renal Cell Carcinoma Treated with Pazopanib.
    Oncology, 2015, Volume: 89, Issue:4

    Topics: Adolescent; Albumins; Alkaline Phosphatase; Bone Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Double-Blind Method; Humans; Indazoles; Kidney Neoplasms; Nomograms; Prognosis; Pyrimidines; Sulfonamides

2015
Radiation Recall Dermatitis With Concomitant Dabrafenib and Pazopanib Therapy.
    JAMA dermatology, 2016, 05-01, Volume: 152, Issue:5

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Diagnosis, Differential; Femoral Neoplasms; Fracture Fixation, Intramedullary; Fractures, Spontaneous; Humans; Imidazoles; Indazoles; Lung Neoplasms; Male; Middle Aged; Oximes; Pyrimidines; Radiodermatitis; Radiotherapy, Adjuvant; Sulfonamides

2016
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-20, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Carcinoma, Renal Cell; Double-Blind Method; Female; Humans; Indazoles; International Agencies; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Placebos; Prognosis; Pyrimidines; Sulfonamides; Survival Rate; Treatment Outcome; Young Adult

2010
Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study.
    The Lancet. Oncology, 2007, Volume: 8, Issue:11

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Axitinib; Bone Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Imidazoles; Indazoles; Interferon-alpha; Interleukin-2; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Treatment Outcome

2007
The antiemetic effect of granisetron in lower hemibody radiotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1991, Volume: 3, Issue:5

    Topics: Aged; Antiemetics; Bone Neoplasms; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Prospective Studies; Radiotherapy; Vomiting

1991

Other Studies

34 other study(ies) available for indazoles and Bone Cancer

ArticleYear
Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.
    Molecular cancer therapeutics, 2022, 07-05, Volume: 21, Issue:7

    Topics: Animals; Bone Neoplasms; Humans; Indazoles; Male; Mice; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Prostate; Prostatic Neoplasms; Tissue Distribution

2022
GSK343 induces programmed cell death through the inhibition of EZH2 and FBP1 in osteosarcoma cells.
    Cancer biology & therapy, 2020, Volume: 21, Issue:3

    Topics: Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Fructose-Bisphosphatase; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Osteosarcoma; Pyridones; Tumor Cells, Cultured

2020
Bone metastasis is associated with poor prognosis in metastatic papillary renal cell carcinoma patients treated with first agent angiogenesis inhibitors.
    Urologic oncology, 2020, Volume: 38, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Axitinib; Bone Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indazoles; Kidney Neoplasms; Male; Middle Aged; Prognosis; Pyrimidines; Retrospective Studies; Sorafenib; Sulfonamides; Sunitinib; Survival Rate; Treatment Outcome

2020
Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma.
    Molecular medicine reports, 2020, Volume: 22, Issue:2

    Topics: Animals; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glycine; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Indazoles; Microwaves; Osteosarcoma; Quinoxalines; Rabbits; Radiofrequency Ablation; Transforming Growth Factor beta1; Tumor Burden

2020
Anticancer effects of the PLK4 inhibitors CFI-400945 and centrinone in Ewing's sarcoma cells.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Humans; Indazoles; Indoles; Membrane Potential, Mitochondrial; Protein Serine-Threonine Kinases; Pyrimidines; Sarcoma, Ewing; Sulfones

2020
Design of new disubstituted imidazo[1,2-
    Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1

    Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Bone Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cyclin B; Drug Screening Assays, Antitumor; Histones; Humans; Indazoles; Intracellular Signaling Peptides and Proteins; Molecular Docking Simulation; Osteosarcoma; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridazines; Structure-Activity Relationship

2020
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
    ACS applied materials & interfaces, 2020, Oct-28, Volume: 12, Issue:43

    Topics: Antineoplastic Agents; Bone Neoplasms; Cell Death; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Nanoparticles; Osteosarcoma; Particle Size; RNA, Small Interfering; Surface Properties; Tumor Cells, Cultured; Tumor Microenvironment; Zinc Oxide

2020
Real-world outcomes of patients with locally advanced or metastatic epithelioid sarcoma.
    Cancer, 2021, 04-15, Volume: 127, Issue:8

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Deoxycytidine; Female; Gemcitabine; Health Records, Personal; Humans; Indazoles; Kaplan-Meier Estimate; Male; Middle Aged; Progression-Free Survival; Pyrimidines; Retrospective Studies; Sarcoma; Sulfonamides; Treatment Outcome; United States; Young Adult

2021
An mTOR and VEGFR inhibitor combination arrests a doxorubicin resistant lung metastatic osteosarcoma in a PDOX mouse model.
    Scientific reports, 2021, 04-21, Volume: 11, Issue:1

    Topics: Adolescent; Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Everolimus; Female; Humans; Indazoles; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Pyrimidines; Receptors, Vascular Endothelial Growth Factor; Sulfonamides; TOR Serine-Threonine Kinases

2021
Pazopanib for second recurrence of osteosarcoma in pediatric patients.
    Pediatrics international : official journal of the Japan Pediatric Society, 2017, Volume: 59, Issue:8

    Topics: Adolescent; Angiogenesis Inhibitors; Bone Neoplasms; Child; Female; Humans; Indazoles; Liver Neoplasms; Lung Neoplasms; Male; Osteosarcoma; Pyrimidines; Sulfonamides

2017
Clinical benefit of antiangiogenic therapy in advanced and metastatic chondrosarcoma.
    Medical oncology (Northwood, London, England), 2017, Aug-29, Volume: 34, Issue:10

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chondrosarcoma; Disease-Free Survival; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Neoplasms, Connective and Soft Tissue; Pyrimidines; Ramucirumab; Retrospective Studies; Sulfonamides; Treatment Outcome

2017
Bindarit Attenuates Pain and Cancer-Related Inflammation by Influencing Myeloid Cells in a Model of Bone Cancer.
    Archivum immunologiae et therapiae experimentalis, 2018, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinogenesis; Cell Line, Tumor; Chemokine CCL2; Disease Models, Animal; Humans; I-kappa B Kinase; Indazoles; Inflammation; Male; Mice; Mice, Nude; Myeloid Cells; Neoplasms, Experimental; Propionates; Signal Transduction; Tumor Burden

2018
The Successful Treatment of Metastatic Extraosseous Ewing Sarcoma with Pazopanib.
    Internal medicine (Tokyo, Japan), 2018, Sep-15, Volume: 57, Issue:18

    Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Agents; Bone Neoplasms; Female; Humans; Indazoles; Lung Neoplasms; Pyrimidines; Sarcoma, Ewing; Sulfonamides; Vaginal Neoplasms

2018
Safety and efficacy of nivolumab for metastatic renal cell carcinoma: real-world results from an expanded access programme.
    BJU international, 2019, Volume: 123, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Immunological; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Everolimus; Female; Humans; Indazoles; Kidney Neoplasms; Male; Middle Aged; Nivolumab; Progression-Free Survival; Pyrimidines; Response Evaluation Criteria in Solid Tumors; Retreatment; Sulfonamides; Sunitinib; Survival Rate

2019
Long-term survival of a patient with neurofibromatosis type 1 diagnosed with multiple malignant peripheral nerve sheath tumors.
    The Journal of dermatology, 2019, Volume: 46, Issue:1

    Topics: Adult; Aged; Bone and Bones; Bone Neoplasms; Humans; Indazoles; Magnetic Resonance Imaging; Middle Aged; Neoplasms, Second Primary; Nerve Sheath Neoplasms; Neurofibromatosis 1; Pyrimidines; Radiotherapy, Adjuvant; Skin; Skin Neoplasms; Sulfonamides; Time Factors; Treatment Outcome

2019
Pazopanib in relapsed osteosarcoma patients: report on 15 cases.
    Acta oncologica (Stockholm, Sweden), 2019, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Angiogenesis Inhibitors; Bone Neoplasms; Child; Female; Humans; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Progression-Free Survival; Pyrimidines; Salvage Therapy; Sulfonamides; Young Adult

2019
Response to Pazopanib in Patients With Relapsed Osteosarcoma.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:4

    Topics: Adult; Bone Neoplasms; Female; Humans; Indazoles; Male; Neoplasm Recurrence, Local; Osteosarcoma; Pyrimidines; Sulfonamides

2020
Efficacy of First-Line Targeted Therapy in Real-World Korean Patients with Metastatic Renal Cell Carcinoma: Focus on Sunitinib and Pazopanib.
    Journal of Korean medical science, 2018, Dec-17, Volume: 33, Issue:51

    Topics: Aged; Bone Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indazoles; Kaplan-Meier Estimate; Kidney Neoplasms; Liver Neoplasms; Male; Middle Aged; Prognosis; Proportional Hazards Models; Protein Kinase Inhibitors; Pyrimidines; Retrospective Studies; Sulfonamides; Sunitinib; Treatment Outcome

2018
Combination of zoledronic Acid and targeted therapy is active but may induce osteonecrosis of the jaw in patients with metastatic renal cell carcinoma.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2013, Volume: 71, Issue:9

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Renal Cell; Cohort Studies; Diphosphonates; Everolimus; Female; Follow-Up Studies; Fractures, Spontaneous; Humans; Imidazoles; Indazoles; Indoles; Interleukin-2; Kidney Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Radiography, Panoramic; Retrospective Studies; Sirolimus; Sorafenib; Spinal Cord Compression; Sulfonamides; Sunitinib; Survival Rate; Zoledronic Acid

2013
Prognostic significance of bone metastases and bisphosphonate therapy in patients with renal cell carcinoma.
    European urology, 2014, Volume: 66, Issue:3

    Topics: Aged; Antineoplastic Agents; Axitinib; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Disease-Free Survival; Female; Humans; Hypocalcemia; Imidazoles; Indazoles; Indoles; Interferon-alpha; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Pamidronate; Phenylurea Compounds; Prognosis; Pyrroles; Renal Insufficiency; Retrospective Studies; Sirolimus; Sorafenib; Sunitinib; Survival Rate; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A; Zoledronic Acid

2014
Pazopanib in metastatic osteosarcoma: significant clinical response in three consecutive patients.
    Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:10

    Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Female; Humans; Humerus; Indazoles; Lung Neoplasms; Male; Neoplasms, Radiation-Induced; Osteosarcoma; Pyrimidines; Skull Neoplasms; Sulfonamides; Young Adult

2014
Axitinib and crizotinib combination therapy inhibits bone loss in a mouse model of castration resistant prostate cancer.
    BMC cancer, 2014, Oct-02, Volume: 14

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bone Density; Bone Neoplasms; Cell Line, Tumor; Crizotinib; Humans; Imidazoles; Indazoles; Male; Mice, Inbred NOD; Mice, SCID; Prostatic Neoplasms, Castration-Resistant; Pyrazoles; Pyridines; Xenograft Model Antitumor Assays

2014
Response of refractory Ewing sarcoma to pazopanib.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:7

    Topics: Angiogenesis Inhibitors; Bone Neoplasms; Female; Humans; Indazoles; Neoplasm Recurrence, Local; Pyrimidines; Salvage Therapy; Sarcoma, Ewing; Sulfonamides; Young Adult

2015
Reversible hair depigmentation in a Japanese female treated with pazopanib.
    The Journal of dermatology, 2014, Volume: 41, Issue:11

    Topics: Adult; Bone Neoplasms; Female; Hair Diseases; Hip Joint; Humans; Indazoles; Pigmentation Disorders; Protein-Tyrosine Kinases; Pyrimidines; Sarcoma; Sulfonamides

2014
Successful Control of Carcinoma of Unknown Primary with Axitinib, a Novel Molecular-Targeted Agent: A Case Report.
    Chemotherapy, 2014, Volume: 60, Issue:5-6

    Topics: Axitinib; Bone Neoplasms; Drug Delivery Systems; Humans; Imidazoles; Indazoles; Male; Middle Aged; Neoplasms, Unknown Primary; Treatment Outcome

2014
Long-term survival following multidisciplinary treatment of metastatic sarcomatoid renal cell carcinoma: a case report.
    Journal of medical case reports, 2015, Nov-19, Volume: 9

    Topics: Antineoplastic Agents; Axitinib; Biopsy; Bone Neoplasms; Carcinoma, Renal Cell; Combined Modality Therapy; Everolimus; Female; Humans; Imidazoles; Indazoles; Interferon-alpha; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Middle Aged; Protein Kinase Inhibitors; Quality of Life; Radiotherapy; Survivors; Tomography, X-Ray Computed

2015
Early Tumour Shrinkage: A Tool for the Detection of Early Clinical Activity in Metastatic Renal Cell Carcinoma.
    European urology, 2016, Volume: 70, Issue:6

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Bone Neoplasms; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease-Free Survival; Humans; Imidazoles; Indazoles; Indoles; Interferon-alpha; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Proportional Hazards Models; Pyrroles; Remission Induction; Retrospective Studies; Sirolimus; Sorafenib; Sunitinib; Survival Rate; Treatment Outcome; Tumor Burden

2016
Fuse-binding protein 1 is a target of the EZH2 inhibitor GSK343, in osteosarcoma cells.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Apoptosis; Autophagy; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; DNA Helicases; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Humans; Indazoles; Osteosarcoma; Proto-Oncogene Proteins c-myc; Pyridones; RNA-Binding Proteins

2016
Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion.
    Oncology, 2016, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Crizotinib; Female; Humans; Indazoles; Intestinal Neoplasms; Liver Neoplasms; Male; Middle Aged; Neuroectodermal Tumors; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Pyrimidines; Receptor Protein-Tyrosine Kinases; Response Evaluation Criteria in Solid Tumors; Sulfonamides; Vascular Endothelial Growth Factor A; Young Adult

2016
Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia.
    Pain, 2009, Volume: 142, Issue:1-2

    Topics: Analgesics; Animals; Body Temperature; Bone Neoplasms; Calcium; Disease Models, Animal; Drug Interactions; Fever; Indazoles; Inflammation; Male; Mice; Mice, Inbred C3H; Motor Activity; Osteoarthritis; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; TRPV Cation Channels; Urea

2009
ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Proliferation; Down-Regulation; Humans; Indazoles; Mice; Mice, Inbred NOD; Mice, SCID; Phenylurea Compounds; Proto-Oncogene Proteins c-kit; Receptor, Platelet-Derived Growth Factor beta; Sarcoma, Ewing; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Dynamic analysis of lung metastasis by mouse osteosarcoma LM8: VEGF is a candidate for anti-metastasis therapy.
    Clinical & experimental metastasis, 2013, Volume: 30, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Movement; Cell Proliferation; Coculture Techniques; Immunoenzyme Techniques; Indazoles; Lung Neoplasms; Mice; Mice, Inbred C3H; Osteosarcoma; Pyrimidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2013
Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer.
    Cancer research, 2007, May-01, Volume: 67, Issue:9

    Topics: Animals; Bone Neoplasms; Breast Neoplasms; Caspase 3; Cell Hypoxia; Cell Line, Tumor; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mice; Mice, Inbred C3H; Mice, Nude; Recombinant Fusion Proteins; Transfection

2007
Effects of synthetic peptido-leukotrienes on bone resorption in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:4

    Topics: Animals; Binding, Competitive; Bone and Bones; Bone Neoplasms; Bone Resorption; Calcium; Cells, Cultured; Chickens; Female; Giant Cell Tumor of Bone; Humans; Indazoles; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Membrane Proteins; Mice; Organ Culture Techniques; Osteoclasts; Radioligand Assay; Rats; Receptors, Leukotriene; Tumor Cells, Cultured

1996