Page last updated: 2024-08-21

indazoles and Body Weight

indazoles has been researched along with Body Weight in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.13)18.7374
1990's6 (19.35)18.2507
2000's10 (32.26)29.6817
2010's9 (29.03)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Baumann, K; Baurain, JF; Calvert, PM; Denys, H; Follana, P; Gaba, L; Ghamande, SA; González-Martín, A; Graybill, WS; Guerra, EM; Gupta, D; Korach, J; Li, Y; Malinowska, IA; Mirza, MR; Monk, BJ; O'Malley, DM; Pisano, C; Prendergast, E; Rose, PG; Stephanie Yap, OW1
Cefalu, M; Guo, A; Ho, TH; Janssen, P; Justice, C; Kempton, A; Makara, M; Smith, SA1
Berek, JS; Berton-Rigaud, D; Colombo, N; Ellard, S; Ghatage, P; Gonzalez-Martin, A; Guo, W; Hazard, S; Ledermann, J; Lesoin, A; Madry, R; Mahner, S; Matulonis, UA; Mirza, MR; Peen, U; Pineda, M; Redondo, A; Reinthaller, A; Rosengarten, O; Sehouli, J; Vergote, I1
Cacanyiova, S; Kristek, F; Malekova, M; Ondrias, K1
Amantea, MA; Brennan, M; Garrett, M; Hee, B; Pithavala, YK; Poland, B1
Davis, JM; Guglielmotti, A; McClellan, JL; Murphy, EA; Steiner, JL1
Cheruvallath, Z; Dougan, DR; Erikson, P; Farrell, P; Feng, J; Holub, C; Komandla, M; Larson, C; Lawson, JD; McBride, C; Miura, J; Plonowski, A; Tang, M; Ton-Nu, T; Vanderpool, D; Wu, Y1
Kalinic, L; Katalenic, D; Makarevic, J; Marijic, VF; Radacic, M; Stojkovic, R1
Cacanyiova, S; Gerova, M; Kristek, F1
Baluchnejadmojarad, T; Roghani, M1
Kompella, UB; Rao, VR; Scheinman, RI; Thakur, A1
Lazzari, P; Mastinu, A; Pani, L; Pinna, GA; Pira, M1
Bezin, L; Corcoran, GB; Groc, L; Jackson Hunter, T; Jiang, H; Koubi, D; Levine, RA1
Gerstberger, R; Horowitz, M; Schwimmer, H2
Hayashi, A; Kimura, Y; Miyata, K; Sasamata, M; Sonoda, R; Suzuki, M; Takasu, T1
Allard, J; Arnal, JF; Escourrou, G; Gamé, X; Gourdy, P; Malavaud, B; Rischmann, P; Tack, I1
Attardi, B; Chakrasali, R; Georg, GI; Hild, SA; Jakkaraj, SR; Tash, JS1
Bardin, CW; Gunsalus, GL; Lobl, TJ; Musto, NA1
Caputo, A1
Barcellona, PS; Campana, A; Cioli, V; Heywood, R; James, RW1
Ansari, AS; Kumar, Y; Lohiya, NK; Srivastava, S1
Bespalov, AY; Dravolina, OA; Medvedev, IO1
Azuma, H; Goto, M; Hamasaki, H; Masuda, H; Sato, J; Sugimoto, A; Tamaoki, S; Yamashita, H1
Mizuno, M; Nabeshima, T; Nawa, H; Olariu, A; Yamada, K1
Cheng, CY; Grima, J; Silvestrini, B1
Abraham, R; Coulston, F; Dougherty, WJ; LeFevre, R; Silvestrini, B1
Glazer, EA; McFarland, JW; Newcomb, DM; Ricketts, AP; Shively, JE1
Berger, MR; Keppler, BK; Seelig, MH1
Ansari, AS; Lohiya, NK; Scorza Barcellona, P1
Boranić, M; Gajsak, V; Jercić, J; Lelieveld, P; Mihalić, H; Radacić, M; Skarić, D; Skarić, V1

Trials

2 trial(s) available for indazoles and Body Weight

ArticleYear
Prospective evaluation of the tolerability and efficacy of niraparib dosing based on baseline body weight and platelet count: Results from the PRIMA/ENGOT-OV26/GOG-3012 trial.
    Cancer, 2023, 06-15, Volume: 129, Issue:12

    Topics: Body Weight; Carcinoma, Ovarian Epithelial; Female; Humans; Indazoles; Ovarian Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Prospective Studies

2023
Safety and dose modification for patients receiving niraparib.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 08-01, Volume: 29, Issue:8

    Topics: Administration, Oral; Adult; Body Weight; Dose-Response Relationship, Drug; Female; Humans; Incidence; Indazoles; Maintenance Chemotherapy; Neoplasm Recurrence, Local; Ovarian Neoplasms; Piperidines; Platelet Count; Poly(ADP-ribose) Polymerase Inhibitors; Progression-Free Survival; Retrospective Studies; Risk Factors; Thrombocytopenia

2018

Other Studies

29 other study(ies) available for indazoles and Body Weight

ArticleYear
Pazopanib for renal cell carcinoma leads to elevated mean arterial pressures in a murine model.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Arterial Pressure; Body Weight; Carcinoma, Renal Cell; Cardiac Output; Disease Models, Animal; Echocardiography; Electrocardiography; Heart; Hypertension; Indazoles; Kidney; Kidney Neoplasms; Mice; Myocardium; Pyrimidines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfonamides; Vascular Endothelial Growth Factor A

2018
Blood pressure-independent hypotrophy of the heart, kidneys and conduit arteries after 7-nitroindazole administration to Wistar rats from the prenatal period to adulthood.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:1

    Topics: Animals; Aorta, Thoracic; Arterial Pressure; Body Weight; Carotid Arteries; Female; Heart; Indazoles; Kidney; Myocardium; Nitric Oxide Synthase Type I; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar

2013
Population pharmacokinetic analysis of axitinib in healthy volunteers.
    British journal of clinical pharmacology, 2014, Volume: 77, Issue:3

    Topics: Adult; Angiogenesis Inhibitors; Aryl Hydrocarbon Hydroxylases; Axitinib; Biotransformation; Body Weight; Clinical Trials, Phase I as Topic; Cytochrome P-450 CYP2C19; Drug Dosage Calculations; Female; Genotype; Glucuronosyltransferase; Healthy Volunteers; Humans; Imidazoles; Indazoles; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Pharmacogenetics; Phenotype; Protein Kinase Inhibitors; Young Adult

2014
Effects of the MCP-1 synthesis inhibitor bindarit on tumorigenesis and inflammatory markers in the C3(1)/SV40Tag mouse model of breast cancer.
    Cytokine, 2014, Volume: 66, Issue:1

    Topics: Animals; Antigens, Polyomavirus Transforming; Biomarkers; Body Weight; Carcinogenesis; Chemokine CCL2; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Indazoles; Inflammation Mediators; Interleukin-6; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Organ Size; Propionates; RNA, Messenger; Spleen; Tumor Burden; Tumor Necrosis Factor-alpha

2014
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 1.
    Bioorganic & medicinal chemistry letters, 2016, Jun-15, Volume: 26, Issue:12

    Topics: Administration, Oral; Aminopeptidases; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Glycoproteins; Humans; Indazoles; Methionyl Aminopeptidases; Mice; Mice, Obese; Models, Molecular; Molecular Structure; Obesity; Structure-Activity Relationship

2016
Reduction of cisplatin-induced nephrotoxicity by pyrazolone compounds, derivatives of tetrahydroindazolonedicarboxylic acid.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:9

    Topics: Animals; Antineoplastic Agents; Blood Urea Nitrogen; Body Weight; Cisplatin; Indazoles; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred BALB C; Pyrazolones

2008
Hypotrophic effect of long-term neuronal NO-synthase inhibition on heart and conduit arteries of the Wistar rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:2

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Carotid Arteries; Coronary Vessels; Dose-Response Relationship, Drug; In Vitro Techniques; Indazoles; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type I; Organ Size; Rats; Rats, Wistar; Time Factors

2009
Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress.
    Behavioural brain research, 2011, Oct-31, Volume: 224, Issue:2

    Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; Hippocampus; Indazoles; Learning Disabilities; Male; Malondialdehyde; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitrites; Oxidative Stress; Rats; Rats, Wistar

2011
Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage.
    Microvascular research, 2011, Volume: 82, Issue:3

    Topics: Administration, Ophthalmic; Animals; Blood Glucose; Blood Proteins; Blood-Retinal Barrier; Body Weight; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Indazoles; Leukocytes; Leukostasis; Macular Edema; Male; Molecular Targeted Therapy; Ophthalmic Solutions; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Inbred BN; Sulfonamides; Time Factors; Vitreous Body

2011
NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Analysis of Variance; Animals; Anti-Obesity Agents; Blood Glucose; Body Mass Index; Body Weight; Brain-Derived Neurotrophic Factor; Cannabinoid Receptor Antagonists; Cholesterol; Dietary Fats; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypothalamus; Indazoles; Intra-Abdominal Fat; Liver; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factor; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Serotonin Plasma Membrane Transport Proteins; Thiophenes; Transaminases; Triglycerides

2012
Nitric oxide synthase inhibition during development: effect on apoptotic death of dopamine neurons.
    Brain research. Developmental brain research, 2002, Oct-20, Volume: 138, Issue:2

    Topics: Animals; Animals, Newborn; Apoptosis; Body Weight; Dopamine; Enzyme Inhibitors; Female; Immunohistochemistry; In Situ Nick-End Labeling; Indazoles; NADPH Dehydrogenase; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pregnancy; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase

2002
Nitric oxide and angiotensin II: neuromodulation of thermoregulation during combined heat and hypohydration stress.
    Brain research, 2004, May-01, Volume: 1006, Issue:2

    Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Body Temperature; Body Temperature Regulation; Body Weight; Cell Membrane; Cell Nucleus; Dehydration; Drug Interactions; Enzyme Inhibitors; Heat Stress Disorders; Indazoles; Injections, Intraventricular; Losartan; Male; Nitric Oxide; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salivation; Vasodilation

2004
Antiobesity effect of YM348, a novel 5-HT2C receptor agonist, in Zucker rats.
    Brain research, 2004, Jun-18, Volume: 1011, Issue:2

    Topics: Aminopyridines; Animals; Anti-Obesity Agents; Blood Glucose; Body Temperature; Body Weight; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Eating; Energy Intake; Indazoles; Indoles; Insulin; Lipids; Male; Obesity; Rats; Rats, Zucker; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Time Factors; Weight Gain

2004
Heat acclimation affects the neuromodulatory role of AngII and nitric oxide during combined heat and hypohydration stress.
    Brain research. Molecular brain research, 2004, Nov-04, Volume: 130, Issue:1-2

    Topics: Acclimatization; Analysis of Variance; Angiotensin II; Animals; Behavior, Animal; Body Weight; Drug Combinations; Enzyme Inhibitors; Gene Expression Regulation; Hot Temperature; Indazoles; Injections, Intraventricular; Male; Models, Biological; Nitric Oxide; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Salivation; Stress, Physiological; Vasodilation; Water Deprivation

2004
Estradiol increases urethral tone through the local inhibition of neuronal nitric oxide synthase expression.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:3

    Topics: Animals; Blotting, Western; Body Weight; Estradiol; Estrus; Female; Indazoles; Mice; Mice, Inbred C57BL; Muscle Tonus; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Organ Size; Ovariectomy; Urethra; Urinary Bladder; Urination

2008
A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose.
    Biology of reproduction, 2008, Volume: 78, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Female; Fertility; Follicle Stimulating Hormone; Genitalia, Male; Hydrazines; Indazoles; Inhibins; Male; Organ Size; Pregnancy; Rats; Rats, Long-Evans; Spermatogenesis; Spermatogenesis-Blocking Agents; Testis; Time Factors

2008
Effects of Lonidamine (AF 1890) and its analogues on follicle-stimulating hormone, luteinizing hormone, testosterone and rat androgen binding protein concentrations in the rat and rhesus monkey.
    Chemotherapy, 1981, Volume: 27 Suppl 2

    Topics: Androgen-Binding Protein; Animals; Antispermatogenic Agents; Body Weight; Carrier Proteins; Follicle Stimulating Hormone; Indazoles; Luteinizing Hormone; Macaca mulatta; Male; Organ Size; Pyrazoles; Rats; Sperm Count; Testis; Testosterone; Time Factors

1981
Preliminary results in some tumor systems with indazolecarboxylic acids.
    Chemotherapy, 1981, Volume: 27 Suppl 2

    Topics: Animals; Body Weight; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Germ Cells; Glycolysis; Indazoles; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazoles; Time Factors

1981
Toxicological studies on 1-substituted-indazole-3-carboxylic acids.
    Chemotherapy, 1981, Volume: 27 Suppl 2

    Topics: Animals; Antispermatogenic Agents; Body Weight; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Indazoles; Kidney; Lethal Dose 50; Macaca mulatta; Male; Mice; Organ Size; Pituitary Gland; Prostate; Pyrazoles; Rats; Semen; Testis

1981
Long-term sequelae of tolnidamine on male reproduction and general body metabolism in rabbits.
    Contraception, 1998, Volume: 57, Issue:4

    Topics: Animals; Antispermatogenic Agents; Body Weight; Dose-Response Relationship, Drug; Fertility; Hematologic Tests; Indazoles; Libido; Male; Semen; Testis; Testosterone

1998
Differential effects of nitric oxide synthase inhibitor, 7-nitroindazole, on discriminative stimulus and somatic effects of naloxone in morphine-dependent rats.
    European journal of pharmacology, 1999, Jul-21, Volume: 377, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Body Weight; Discrimination Learning; Drug Interactions; Enzyme Inhibitors; Indazoles; Male; Maze Learning; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Substance-Related Disorders

1999
ATZ1993, an orally active and novel nonpeptide antagonist for endothelin receptors and inhibition of intimal hyperplasia after balloon denudation of the rabbit carotid artery.
    Japanese journal of pharmacology, 1999, Volume: 81, Issue:1

    Topics: Administration, Oral; Angioplasty, Balloon; Animals; Blood Pressure; Body Weight; Carotid Artery Injuries; Carotid Artery, Common; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; Humans; Hyperplasia; Indazoles; Male; Muscle, Smooth, Vascular; Rabbits; Receptors, Endothelin; Swine; Tunica Intima

1999
Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Sep-15, Volume: 20, Issue:18

    Topics: Analysis of Variance; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Eating; Frontal Lobe; Hippocampus; Indazoles; Injections, Intraventricular; Male; Maze Learning; Motor Activity; Nitric Oxide Synthase; Oligonucleotides, Antisense; Rats; Rats, Wistar; Retention, Psychology; RNA, Messenger; Spatial Behavior

2000
Reversible inhibition of spermatogenesis in rats using a new male contraceptive, 1-(2,4-dichlorobenzyl)-indazole-3-carbohydrazide.
    Biology of reproduction, 2001, Volume: 64, Issue:5

    Topics: Animals; Antispermatogenic Agents; Body Weight; Brain; Contraceptive Agents, Male; Epididymis; Female; Fertility; Follicle Stimulating Hormone; Hydrazines; Indazoles; Kidney; Litter Size; Liver; Luteinizing Hormone; Male; Organ Size; Prostate; Rats; Rats, Sprague-Dawley; Spermatogenesis; Testis; Testosterone

2001
Reversible inhibition of spermatogenesis in rats and monkeys with a new class of indazol-carboxylic acids.
    Experimental and molecular pathology, 1975, Volume: 23, Issue:2

    Topics: Animals; Antispermatogenic Agents; Body Weight; Dose-Response Relationship, Drug; Haplorhini; Indazoles; Macaca mulatta; Male; Organ Size; Pyrazoles; Rats; Seminiferous Epithelium; Sertoli Cells; Spermatocytes; Spermatogonia; Spermatozoa; Testis

1975
Anticoccidial activities of 7-bromo-N-(2-imidazolidinylidene)-1H-indazol-6-amine and other alpha 2 adrenergic agonists.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Body Weight; Chickens; Clonidine; Coccidiosis; Coccidiostats; Eimeria tenella; Imidazoles; Indazoles; Male; Poultry Diseases

1992
Antineoplastic activity of three ruthenium derivatives against chemically induced colorectal carcinoma in rats.
    Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:3

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma; Colorectal Neoplasms; Dose-Response Relationship, Drug; Imidazoles; Indazoles; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Ruthenium

1992
Antispermatogenic effects of tolnidamine in langur (Presbytis entellus).
    Contraception, 1991, Volume: 43, Issue:5

    Topics: Acid Phosphatase; Animals; Antispermatogenic Agents; Blood Chemical Analysis; Body Weight; Cercopithecidae; Fructose; Glycerylphosphorylcholine; Indazoles; L-Lactate Dehydrogenase; Leydig Cells; Libido; Magnesium; Male; Semen; Seminiferous Tubules; Sertoli Cells; Sperm Count; Sperm Motility; Spermatozoa; Testosterone

1991
Reduction of cis-dichlorodiammineplatinum(II) caused nephrotoxicity by indazolone carboxylic acid.
    Oncology, 1987, Volume: 44, Issue:1

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Cell Division; Cell Survival; Cisplatin; Indazoles; Kidney; Kidney Diseases; Leukemia L1210; Male; Mice; Mice, Inbred CBA; Necrosis; Pyrazoles

1987