indazoles and Asthma
indazoles has been researched along with Asthma in 14 studies
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Begg, M; Cahn, A; Cui, Y; Hamblin, JN; Hessel, EM; Hogg, A; Khindri, S; Kornmann, O; Leemereise, C; Ludwig-Sengpiel, A; Montembault, M; Robertson, J; Wajdner, H; Yang, S | 1 |
| Norman, P | 1 |
| Carreño, C; De Alba, J; Domènech, A; Eichhorn, P; Fernández, JC; Maldonado, M; Miralpeix, M; Orellana, A; Otal, R; Prats, N; Ramis, I; Vidal, B | 1 |
| Amour, A; Baldwin, IR; Cooper, AW; Deakin, AM; Down, K; Felton, LM; Guntrip, SB; Hamblin, JN; Hardy, C; Harrison, ZA; Jones, KL; Jones, P; Keeling, SE; Le, J; Livia, S; Lucas, F; Lunniss, CJ; Parr, NJ; Robinson, E; Rowland, P; Smith, S; Thomas, DA; Vitulli, G; Washio, Y | 1 |
| Liu, C; Wang, X; Wu, L; Zhu, S | 1 |
| Amilon, C; Bäckman, P; Cleton, A; Hamrén, UW; Jorup, C; Kloft, C; Melin, J; Olsson, B; Prothon, S | 1 |
| Bonar, SL; Brustkern, SJ; Chen, NX; Christine, L; Heier, RF; Hu, Y; Huang, HC; Kishore, NN; Kurumbail, RG; Lennon, PJ; Li, X; Mathialagan, S; Poda, GI; Reding, MT; Selness, SR; Sommers, CD; Venkatraman, N; Wolfson, SG; Xie, J | 1 |
| Akong-Moore, K; Broide, DH; Cho, JY; Cowburn, AS; Crotty Alexander, LE; Feldstein, S; Isaacs, H; Johansson, P; Johnson, RS; McEachern, EK; Nguyen, A; Nicatia, S; Nizet, V; Olson, J | 1 |
| Brink, C; Gascard, JP; Gorenne, I; Labat, C | 1 |
| Callens, E; Djebbar, R; Ruff, F; Santais, MC | 1 |
| Giovanazzi, S; Mezzetti, M; Nicosia, S; Rovati, GE | 1 |
| Björck, T; Dahlén, B; Dahlén, SE; Harada, Y; Hedqvist, P; Johansson, G; Rodriguez, L; Zetterström, O | 1 |
| Bernstein, PR; Handley, DA; Harris, KE; Krell, RD; Patterson, R; Saunders, RN | 1 |
| Cloud, ML; Fleisch, JH; Marshall, WS | 1 |
Reviews
2 review(s) available for indazoles and Asthma
| Article | Year |
|---|---|
[Potential importance of antileukotrienes in the treatment of asthma and other inflammatory diseases: apropos of a new pharmacological class].
Topics: Acetophenones; Adult; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Crohn Disease; Cystic Fibrosis; Haplorhini; Humans; Hydroxyurea; Indazoles; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Psoriasis; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sulfonamides; Tetrazoles; Tosyl Compounds | 1998 |
A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
Topics: Acetophenones; Animals; Asthma; Azoles; Bronchi; Chromones; Dicarboxylic Acids; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Indazoles; Leukotriene E4; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles | 1988 |
Trials
2 trial(s) available for indazoles and Asthma
| Article | Year |
|---|---|
A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Crossover Study To Investigate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Repeat Doses of Inhaled Nemiralisib in Adults with Persistent, Uncontrolled Asthma.
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Indazoles; Indoles; Male; Middle Aged; Oxazoles; Phosphatidylinositol 3-Kinases; Piperazines; Vital Capacity; Young Adult | 2018 |
Pharmacokinetics of the Inhaled Selective Glucocorticoid Receptor Modulator AZD5423 Following Inhalation Using Different Devices.
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Dry Powder Inhalers; Humans; Indazoles; Male; Young Adult | 2017 |
Other Studies
10 other study(ies) available for indazoles and Asthma
| Article | Year |
|---|---|
Crystalline forms of 2,2,2-trifluoro-N-[(1R,2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(3-methoxyphenyl)-2-propanyl]acetamide (AZD-5423).
Topics: Acetamides; Administration, Inhalation; Animals; Asthma; Crystallization; Humans; Indazoles; Patents as Topic; Pulmonary Disease, Chronic Obstructive; Receptors, Glucocorticoid | 2013 |
A novel inhaled Syk inhibitor blocks mast cell degranulation and early asthmatic response.
Topics: Administration, Inhalation; Animals; Asthma; Azabicyclo Compounds; B-Lymphocytes; Cell Degranulation; Cell Line; Disease Models, Animal; Humans; Indazoles; Intracellular Signaling Peptides and Proteins; Male; Mast Cells; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Inbred BN; Rats, Wistar; Syk Kinase | 2015 |
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease.
Topics: Administration, Inhalation; Animals; Asthma; Female; Humans; Indazoles; Indoles; Isoenzymes; Male; Microsomes; Molecular Docking Simulation; Ovalbumin; Oxazoles; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Pneumonia; Pulmonary Disease, Chronic Obstructive; Rabbits; Rats; Rats, Sprague-Dawley; Respiratory Tract Diseases; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Th2 Cells | 2015 |
Potent ameliorating effect of Hypoxia-inducible factor 1α (HIF-1α) antagonist YC-1 on combined allergic rhinitis and asthma syndrome (CARAS) in Rats.
Topics: Animals; Anti-Allergic Agents; Asthma; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Lung; Male; Nasal Mucosa; Ovalbumin; PPAR alpha; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; RNA, Messenger; Transcription Factor RelA | 2016 |
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship.
Topics: Administration, Inhalation; Aminopyridines; Asthma; Binding, Competitive; Drug Design; HEK293 Cells; Humans; I-kappa B Kinase; Indazoles; Isonicotinic Acids; Microsomes, Liver; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Niacinamide; Phenethylamines; Potassium Channel Blockers; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Structure-Activity Relationship; Sulfonamides | 2011 |
Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function.
Topics: Airway Resistance; Animals; Asthma; Basic Helix-Loop-Helix Transcription Factors; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemotaxis; Eosinophils; Female; Gene Expression Regulation; Goblet Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Interleukin-13; Interleukin-4; Interleukin-5; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Signal Transduction | 2013 |
Antigen stimulation of human pulmonary smooth muscle: an in vitro model of inflammation.
Topics: Antigens; Asthma; Bronchi; Bronchodilator Agents; Cell Separation; Humans; Hydroxy Acids; Indazoles; Leukotriene D4; Muscle, Smooth; Norepinephrine; Propionates; Pulmonary Veins; Quinolines | 1996 |
Heterogeneity of binding sites for ICI 198,615 in human lung parenchyma.
Topics: Asthma; Binding Sites; Chromones; Dicarboxylic Acids; Humans; Indazoles; Kinetics; Lung; Receptors, Immunologic; Receptors, Leukotriene; Software; SRS-A; Thiazoles | 1992 |
Further evidence that leukotrienes are the major mediators of allergic constriction in human bronchi.
Topics: Allergens; Antibodies, Anti-Idiotypic; Asthma; Bronchi; Bronchoconstriction; Histamine Antagonists; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Indazoles; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged | 1991 |
Effects of combined receptor antagonists of leukotriene D4 (LTD4) and platelet-activating factor (PAF) on rhesus airway responses to LTD4, PAF and antigen.
Topics: Animals; Ascaris; Asthma; Drug Therapy, Combination; Female; Immunoglobulin E; Indazoles; Macaca mulatta; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyrazoles; Quinolinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Leukotriene; SRS-A | 1989 |