Page last updated: 2024-08-21

indazoles and Alzheimer Disease

indazoles has been researched along with Alzheimer Disease in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's7 (50.00)24.3611
2020's6 (42.86)2.80

Authors

AuthorsStudies
Fang, L; Gou, S; Liu, Q; Liu, Z; Zhang, B1
Ann, J; Ha, HJ; Hoang, VH; Jeong, JJ; Kang, S; Kim, H; Kim, YH; Lee, J; Ngo, VTH; Van Manh, N1
Bouissane, L; Catto, M; Eddahmi, M; Hafid, A; Khouili, M; La Spada, G1
Capriati, V; Cardoso, SM; Chaves, S; Costa, M; Gwizdala, K; Josselin, R; Pereira-Santos, AR; Piemontese, L; Resta, S; Rinaldo, F; Santos, MA1
Buabeid, M; Dhanasekaran, M; Dwyer, D; Fabbrini, M; Fujihashi, A; Govindarajulu, M; Lynd, T; Mohanakumar, KP; Moore, T; Neel, L; Ramesh, S; Shah, K; Smith, F1
D'Ascenzo, N; Han, S; He, Z; Hu, X; Jacob, C; Liang, X; Liu, Q; Ni, J; Wan, L; Xiao, P; Xiao, W; Xie, Q1
Cerecetto, H; Damián, A; Engler, H; Fernández, S; Giglio, J; González, M; Oliver, P; Pérez, C; Pérez, DI; Rey, A; Reyes, AL1
Alquézar, C; Bartolomé, F; Campillo, NE; Carro, E; Del Cerro, P; González-Naranjo, P; Martín-Requero, Á; Páez, JA; Pérez, C1
Bednarikova, Z; Gancar, M; Gazova, Z; Hu, CK; Li, MS; Linh, HQ; Thai, NQ1
Arán, VJ; Campillo, NE; Fernández-Ruiz, J; García-Arencibia, M; Girón, R; Gómez-Cañas, M; González-Naranjo, P; Martín, MI; Páez, JA; Pérez, C; Pérez-Macias, N; Sánchez-Robles, E1
Chopra, K; Kuhad, A; Misra, S1
Jones, MR; Mu, C; Storr, T; Walsby, CJ; Wang, MC; Webb, MI1
Chapolikar, AD; Devkate, CG; Domb, AJ; Gaikwad, DD; Pawar, RP; Tayade, AP; Warad, KD1
Chen, JP; Liu, H; Zhang, WQ1

Reviews

2 review(s) available for indazoles and Alzheimer Disease

ArticleYear
Nutraceutical based SIRT3 activators as therapeutic targets in Alzheimer's disease.
    Neurochemistry international, 2021, Volume: 144

    Topics: Aging; Alzheimer Disease; Animals; Biphenyl Compounds; Dietary Supplements; Drug Delivery Systems; Enzyme Inhibitors; Glucosides; Humans; Hydrazines; Indazoles; Lignans; Neuroprotection; Phenols; Sirtuin 3

2021
Synthesis of indazole motifs and their medicinal importance: an overview.
    European journal of medicinal chemistry, 2015, Jan-27, Volume: 90

    Topics: Alzheimer Disease; Antineoplastic Agents; Antipsychotic Agents; Cell Proliferation; Chronic Pain; Humans; Indazoles; Molecular Structure; Narcotics

2015

Other Studies

12 other study(ies) available for indazoles and Alzheimer Disease

ArticleYear
Blood-Brain Barrier Permeable and NO-Releasing Multifunctional Nanoparticles for Alzheimer's Disease Treatment: Targeting NO/cGMP/CREB Signaling Pathways.
    Journal of medicinal chemistry, 2021, 09-23, Volume: 64, Issue:18

    Topics: Alzheimer Disease; Animals; Apoptosis; Cell Line, Tumor; Donepezil; Drug Carriers; Drug Liberation; Humans; Indazoles; Male; Memory; Mice, Inbred BALB C; Mice, Nude; Multifunctional Nanoparticles; Neuronal Plasticity; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nootropic Agents; Oxadiazoles; Purines; Pyrazoles; Rats, Sprague-Dawley; Signal Transduction

2021
Discovery of potent indazole-based human glutaminyl cyclase (QC) inhibitors as Anti-Alzheimer's disease agents.
    European journal of medicinal chemistry, 2022, Dec-15, Volume: 244

    Topics: Alzheimer Disease; Aminoacyltransferases; Amyloid beta-Peptides; Animals; Drug Discovery; Humans; Indazoles

2022
Towards Alzheimer's disease-related targets: One-pot Cu(I)- mediated synthesis of new nitroindazolyltriazoles.
    Bioorganic chemistry, 2023, Volume: 130

    Topics: Alzheimer Disease; Amyloidogenic Proteins; Brain; Catalysis; Cholinesterases; Copper; Indazoles; Monoamine Oxidase; Triazoles

2023
Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
    Molecules (Basel, Switzerland), 2020, Feb-22, Volume: 25, Issue:4

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Chelating Agents; Cholinesterase Inhibitors; Donepezil; Humans; Indazoles; Ligands; Molecular Docking Simulation; Molecular Structure; Piperazine; Piperidines; Structure-Activity Relationship

2020
Effect of Increased IL-1β on Expression of HK in Alzheimer's Disease.
    International journal of molecular sciences, 2021, Jan-28, Volume: 22, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Disease Models, Animal; Female; Hexokinase; Humans; Indazoles; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Transgenic; Nigericin; Positron-Emission Tomography; Thiazolidines; Thiones; Up-Regulation

2021
3-(Benzyloxy)-1-(5-[
    Future medicinal chemistry, 2017, Volume: 9, Issue:10

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Brain; Female; Humans; Indazoles; Mice; Molecular Structure; Positron-Emission Tomography; Tissue Distribution

2017
Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease.
    CNS drugs, 2018, Volume: 32, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Bromodeoxyuridine; Case-Control Studies; Cell Line, Transformed; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Humans; Indazoles; Lymphocytes; Male; Middle Aged; Neuroprotective Agents; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Signal Transduction; Time Factors

2018
Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer's Disease.
    ACS chemical neuroscience, 2018, 11-21, Volume: 9, Issue:11

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Computer Simulation; Humans; In Vitro Techniques; Indazoles; Molecular Dynamics Simulation; Peptide Fragments; Pyridines; Quinazolines

2018
Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease.
    European journal of medicinal chemistry, 2014, Feb-12, Volume: 73

    Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cannabinoid Receptor Agonists; Cholinesterase Inhibitors; Computational Biology; Drug Design; Horses; Humans; Indazoles; Ligands; Molecular Docking Simulation; Molecular Structure; Radioligand Assay; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2

2014
Neurobiological effect of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in experimental paradigm of Alzheimer's disease.
    Indian journal of experimental biology, 2013, Volume: 51, Issue:12

    Topics: Alzheimer Disease; Animals; Cognition Disorders; Enzyme Inhibitors; Humans; Indazoles; Male; Maze Learning; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Streptozocin

2013
Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity.
    Metallomics : integrated biometal science, 2015, Volume: 7, Issue:1

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Humans; Indazoles; Organometallic Compounds; Ruthenium Compounds

2015
[Inducible nitric oxide synthase induces beta-amyloid neurotoxicity in vivo].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2002, Volume: 18, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Guanidines; Indazoles; Male; Maze Learning; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley

2002