indazoles and Allodynia

Topics: Animals; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hyperalgesia; Indazoles; Male; Models, Animal; Pain Measurement; Pain, Postoperative; Phosphorylation; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Rosaniline Dyes; Satellite Cells, Perineuronal; Signal Transduction; Surgical Wound

Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glyburide; Hyperalgesia; Indazoles; Methiothepin; Naloxone; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pain Measurement; Piperazines; Piperidones; Pyridines; Quinoxalines; Rats; Spiro Compounds

Topics: Animals; Arginine; Enzyme Inhibitors; Enzyme Precursors; Facial Pain; Hyperalgesia; Indazoles; Lip; Male; Mandibular Nerve; Neural Pathways; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Threshold; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Signal Transduction; Touch; Trigeminal Ganglion; Trigeminal Nerve Injuries

Topics: Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Formaldehyde; Hot Temperature; Hyperalgesia; Indazoles; Male; Mice; Modafinil; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain

Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Biological Availability; Calcium Channels; CHO Cells; Cricetulus; Freund's Adjuvant; Humans; Hyperalgesia; Indazoles; Male; Mice, Inbred C57BL; Mustard Plant; Nerve Tissue Proteins; Plant Oils; Rats, Wistar; Species Specificity; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

Topics: Animals; Arachidonic Acids; Cannabinoids; Celecoxib; Cyclooxygenase Inhibitors; Diabetic Neuropathies; Drug Synergism; Hyperalgesia; Indazoles; Lysine; Male; Neuralgia; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Wistar; Streptozocin

Topics: Adjuvants, Immunologic; Animals; Arthralgia; Arthritis, Experimental; Freund's Adjuvant; Hindlimb; Hyperalgesia; Indazoles; Proteinase Inhibitory Proteins, Secretory; Pyrazoles; Rats; Rats, Sprague-Dawley; Tarsal Joints; Weight-Bearing

Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Evaluation, Preclinical; Enzyme Inhibitors; Hyperalgesia; Hypoglycemic Agents; Indazoles; Lysine; Male; Nitric Oxide Synthase; Nitroarginine; Pain Measurement; Rats; Rats, Wistar; Receptors, Bradykinin; Streptozocin; Tetrahydroisoquinolines; Vincristine

Topics: Adenosine Triphosphate; Animals; Cell Movement; Cerebral Cortex; Cinnamates; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hyperalgesia; Indazoles; Intramolecular Oxidoreductases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Microglia; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Prostaglandin-E Synthases; S-Nitrosoglutathione; Spinal Cord; Spinal Nerves

Topics: Animals; Dizocilpine Maleate; Enzyme Inhibitors; Gene Expression Regulation; Hyperalgesia; Indazoles; Male; Memantine; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoplatinum Compounds; Oxaliplatin; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spinal Cord

Topics: Animals; Animals, Newborn; Colon; Colonic Diseases; Disease Models, Animal; Electromyography; Gastrointestinal Motility; Hyperalgesia; Indazoles; Irritable Bowel Syndrome; Male; Maternal Behavior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stress, Psychological

Topics: Animals; Astrocytes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hyperalgesia; Indazoles; JNK Mitogen-Activated Protein Kinases; Male; Neuralgia; Neurons; Nitric Oxide Synthase Type I; Pain Measurement; Phenols; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord

Topics: Animals; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Male; Mice; Nitric Oxide; Nociceptors; Rats; Rats, Wistar; Receptor, PAR-2; Receptors, N-Methyl-D-Aspartate; Receptors, Thrombin

Topics: Acetic Acid; Amino Acid Chloromethyl Ketones; Animals; Behavior, Animal; Capillary Permeability; Endothelins; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; Nociceptors; Oligopeptides; Pain Measurement; Peptide Fragments; Peptides, Cyclic; Physical Stimulation; Piperidines; Reaction Time; Receptor, Endothelin A; Receptor, Endothelin B; Thrombin; Urea

Topics: Analgesics; Animals; Crotalid Venoms; Crotalus; Dinoprostone; Drug Antagonism; Enzyme Inhibitors; Hyperalgesia; Indazoles; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa

Topics: Amidines; Analgesics; Animals; Carrageenan; Cerebellum; Heating; Heterocyclic Compounds, 2-Ring; Humans; Hyperalgesia; Indazoles; Injections, Intraperitoneal; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Recombinant Proteins

Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide Receptor Antagonists; Celecoxib; Citrates; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Interleukin-1; Lysine; Male; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Pain; Physalaemin; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Spider Venoms; Spinal Cord; Sulfonamides; Tumor Necrosis Factor-alpha

Topics: Animals; Blotting, Western; Calcium; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Immunohistochemistry; Indazoles; Inflammation; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Spinal Cord; Tissue Distribution

Topics: Agmatine; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hyperalgesia; Indazoles; Injections, Spinal; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Administration, Oral; Analgesics; Animals; Arthralgia; Calcium; Capsaicin; Cell Line; Cells, Cultured; Central Nervous System; Disease Models, Animal; Humans; Hyperalgesia; Indazoles; Inflammation Mediators; Injections, Spinal; Male; Nociceptors; Pain; Pyridines; Rats; Rats, Sprague-Dawley; Sulfones; Treatment Outcome; TRPV Cation Channels; Urea

Topics: Animals; Dihydrolipoamide Dehydrogenase; Enzyme Inhibitors; Female; Ganglia, Spinal; Herpesvirus 1, Human; Hyperalgesia; Indazoles; Isothiuronium; Mice; Mice, Inbred C57BL; Neuralgia, Postherpetic; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nociceptors; Posterior Horn Cells; RNA, Messenger; Up-Regulation

Topics: Analgesics; Animals; Arthritis; Carrageenan; Hyperalgesia; Indazoles; Inflammation; Injections, Intra-Articular; Isomerism; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hyperalgesia; Indazoles; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Long-Evans; Spinal Cord

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Autoreceptors; Enzyme Inhibitors; Feeding Behavior; Hyperalgesia; Hypothalamus; Indazoles; Male; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists

Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Spinal; Kynurenic Acid; Magnesium Sulfate; Male; Neurons; Nitric Oxide Synthase; Pain Measurement; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spine