Page last updated: 2024-08-21

indazoles and Allodynia

indazoles has been researched along with Allodynia in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (12.00)18.2507
2000's11 (44.00)29.6817
2010's11 (44.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, X; Ruan, X; Song, J; Wang, W; Wei, X; Xu, X; Ying, Y1
Cervantes-Durán, C; Granados-Soto, V; Murbartián, J; Quiñonez-Bastidas, GN; Rocha-González, HI1
Echizenya, S; Honda, K; Ito, R; Iwata, K; Kaji, K; Lee, J; Ohara, K; Shinoda, M; Sugiyama, T; Takahashi, O; Urata, K; Watase, T1
Bhattacharya, SK; Gupta, LK; Gupta, R1
Boissel, V; D'Souza, AM; Devereux, N; Head, V; Lao, J; Masick, B; Nash, M; Panesar, M; Patapoutian, A; Petrassi, HM; Petrus, MJ; Rooney, L; Schumacher, AM; Stoakley, N; Stringer, R; Tully, DC; Verkuyl, JM; Vidal, A; West, R1
Bujalska-Zadrożny, M; de Cordé, A; Pawlik, K1
Cinci, L; Di Cesare Mannelli, L; Ghelardini, C; Maresca, M; Micheli, L; Pacini, A; Paola Giovannoni, M; Quinn, MT; Vergelli, C1
Bujalska, M; Makulska-Nowak, H1
Audoly, LP; Ito, S; Katano, T; Kunori, S; Matsumura, S; Okuda-Ashitaka, E; Urade, Y1
Egashira, N; Ikesue, H; Kawashiri, T; Mihara, Y; Oishi, R; Sada, H; Ushio, S; Yano, T1
Berman, B; Che, CT; Fong, HH; Ip, SP; Lao, L; Sung, JJ; Tjong, YW; Wu, J1
Li, YQ; Mei, XP; Wang, W; Wei, YY; Wu, SX; Xu, LX; Zhang, MM; Zhang, T1
Itoh, H; Kataoka, K; Kawabata, A; Kawao, N; Kuroda, R; Masuko, T; Ogawa, S; Shimada, C; Takebe, K1
Fang, M; Fisher, LL; Kovács, KJ; Larson, AA1
Cury, Y; Picolo, G1
Kamanaka, Y; Kawabata, A; Kawao, N; Matsuya, H; Mita, Y; Sekiguchi, F; Taga, C1
Cury, Y; Longo, I; Zanchet, EM1
Doré, S; Johns, RA; Liaw, WJ; Raja, SN; Tao, F; Tao, YX; Zhao, C1
Fairbanks, CA; Grocholski, BM; Kitto, KF; Roberts, JC1
Bayburt, EK; Bianchi, B; Brown, B; Chandran, P; Cui, M; Decker, MW; Faltynek, CR; Gauvin, D; Gomtsyan, A; Hernandez, G; Honore, P; Lee, CH; Marsh, K; McDonald, H; Mikusa, J; Moreland, RB; Neelands, TR; Niforatos, W; Sullivan, JP; Zhong, C1
Andoh, T; Ito, S; Kuraishi, Y; Mabuchi, T; Sasaki, A; Serizawa, K; Shiraki, K; Takasaki, I1
Lawand, NB; Westlund, KN; Willis, WD1
Coderre, TJ; Osborne, MG1
Sugimoto, Y; Yamada, J; Yoshikawa, T1
Begon, S; Dubray, C; Eschalier, A; Mazur, A; Pickering, G; Rayssiguier, Y1

Other Studies

25 other study(ies) available for indazoles and Allodynia

ArticleYear
The role of P2X7R/ERK signaling in dorsal root ganglia satellite glial cells in the development of chronic postsurgical pain induced by skin/muscle incision and retraction (SMIR).
    Brain, behavior, and immunity, 2018, Volume: 69

    Topics: Animals; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hyperalgesia; Indazoles; Male; Models, Animal; Pain Measurement; Pain, Postoperative; Phosphorylation; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Rosaniline Dyes; Satellite Cells, Perineuronal; Signal Transduction; Surgical Wound

2018
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats.
    Life sciences, 2013, Oct-17, Volume: 93, Issue:17

    Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glyburide; Hyperalgesia; Indazoles; Methiothepin; Naloxone; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pain Measurement; Piperazines; Piperidones; Pyridines; Quinoxalines; Rats; Spiro Compounds

2013
Nitric oxide signaling contributes to ectopic orofacial neuropathic pain.
    Journal of dental research, 2013, Volume: 92, Issue:12

    Topics: Animals; Arginine; Enzyme Inhibitors; Enzyme Precursors; Facial Pain; Hyperalgesia; Indazoles; Lip; Male; Mandibular Nerve; Neural Pathways; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Threshold; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Signal Transduction; Touch; Trigeminal Ganglion; Trigeminal Nerve Injuries

2013
Chronic administration of modafinil induces hyperalgesia in mice: reversal by L-NG-nitro-arginine methyl ester and 7-nitroindazole.
    European journal of pharmacology, 2014, Aug-05, Volume: 736

    Topics: Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Formaldehyde; Hot Temperature; Hyperalgesia; Indazoles; Male; Mice; Modafinil; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain

2014
Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Biological Availability; Calcium Channels; CHO Cells; Cricetulus; Freund's Adjuvant; Humans; Hyperalgesia; Indazoles; Male; Mice, Inbred C57BL; Mustard Plant; Nerve Tissue Proteins; Plant Oils; Rats, Wistar; Species Specificity; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

2014
Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:2

    Topics: Animals; Arachidonic Acids; Cannabinoids; Celecoxib; Cyclooxygenase Inhibitors; Diabetic Neuropathies; Drug Synergism; Hyperalgesia; Indazoles; Lysine; Male; Neuralgia; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Wistar; Streptozocin

2015
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Arthralgia; Arthritis, Experimental; Freund's Adjuvant; Hindlimb; Hyperalgesia; Indazoles; Proteinase Inhibitory Proteins, Secretory; Pyrazoles; Rats; Rats, Sprague-Dawley; Tarsal Joints; Weight-Bearing

2016
Bradykinin receptors antagonists and nitric oxide synthase inhibitors in vincristine and streptozotocin induced hyperalgesia in chemotherapy and diabetic neuropathy rat model.
    Neuro endocrinology letters, 2009, Volume: 30, Issue:1

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Evaluation, Preclinical; Enzyme Inhibitors; Hyperalgesia; Hypoglycemic Agents; Indazoles; Lysine; Male; Nitric Oxide Synthase; Nitroarginine; Pain Measurement; Rats; Rats, Wistar; Receptors, Bradykinin; Streptozocin; Tetrahydroisoquinolines; Vincristine

2009
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord.
    Glia, 2011, Volume: 59, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Movement; Cerebral Cortex; Cinnamates; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hyperalgesia; Indazoles; Intramolecular Oxidoreductases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Microglia; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Prostaglandin-E Synthases; S-Nitrosoglutathione; Spinal Cord; Spinal Nerves

2011
Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.
    Molecular pain, 2011, Jan-20, Volume: 7

    Topics: Animals; Dizocilpine Maleate; Enzyme Inhibitors; Gene Expression Regulation; Hyperalgesia; Indazoles; Male; Memantine; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoplatinum Compounds; Oxaliplatin; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spinal Cord

2011
Role of neuronal nitric oxide synthase in colonic distension-induced hyperalgesia in distal colon of neonatal maternal separated male rats.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:7

    Topics: Animals; Animals, Newborn; Colon; Colonic Diseases; Disease Models, Animal; Electromyography; Gastrointestinal Motility; Hyperalgesia; Indazoles; Irritable Bowel Syndrome; Male; Maternal Behavior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stress, Psychological

2011
Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
    Brain, behavior, and immunity, 2011, Volume: 25, Issue:7

    Topics: Animals; Astrocytes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hyperalgesia; Indazoles; JNK Mitogen-Activated Protein Kinases; Male; Neuralgia; Neurons; Nitric Oxide Synthase Type I; Pain Measurement; Phenols; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord

2011
Role of N-methyl-D-aspartate receptors and the nitric oxide pathway in nociception/hyperalgesia elicited by protease-activated receptor-2 activation in mice and rats.
    Neuroscience letters, 2002, Sep-06, Volume: 329, Issue:3

    Topics: Animals; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Male; Mice; Nitric Oxide; Nociceptors; Rats; Rats, Wistar; Receptor, PAR-2; Receptors, N-Methyl-D-Aspartate; Receptors, Thrombin

2002
Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
    The Journal of physiology, 2003, Jun-15, Volume: 549, Issue:Pt 3

    Topics: Acetic Acid; Amino Acid Chloromethyl Ketones; Animals; Behavior, Animal; Capillary Permeability; Endothelins; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; Nociceptors; Oligopeptides; Pain Measurement; Peptide Fragments; Peptides, Cyclic; Physical Stimulation; Piperidines; Reaction Time; Receptor, Endothelin A; Receptor, Endothelin B; Thrombin; Urea

2003
Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist.
    Life sciences, 2004, Jun-18, Volume: 75, Issue:5

    Topics: Analgesics; Animals; Crotalid Venoms; Crotalus; Dinoprostone; Drug Antagonism; Enzyme Inhibitors; Hyperalgesia; Indazoles; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa

2004
The potent inducible nitric oxide synthase inhibitor ONO-1714 inhibits neuronal NOS and exerts antinociception in rats.
    Neuroscience letters, 2004, Jul-22, Volume: 365, Issue:2

    Topics: Amidines; Analgesics; Animals; Carrageenan; Cerebellum; Heating; Heterocyclic Compounds, 2-Ring; Humans; Hyperalgesia; Indazoles; Injections, Intraperitoneal; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Recombinant Proteins

2004
Involvement of spinal neurokinins, excitatory amino acids, proinflammatory cytokines, nitric oxide and prostanoids in pain facilitation induced by Phoneutria nigriventer spider venom.
    Brain research, 2004, Sep-17, Volume: 1021, Issue:1

    Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide Receptor Antagonists; Celecoxib; Citrates; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Interleukin-1; Lysine; Male; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Pain; Physalaemin; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Spider Venoms; Spinal Cord; Sulfonamides; Tumor Necrosis Factor-alpha

2004
Differential roles of neuronal and endothelial nitric oxide synthases during carrageenan-induced inflammatory hyperalgesia.
    Neuroscience, 2004, Volume: 128, Issue:2

    Topics: Animals; Blotting, Western; Calcium; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Immunohistochemistry; Indazoles; Inflammation; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Spinal Cord; Tissue Distribution

2004
Pharmacodynamic and pharmacokinetic studies of agmatine after spinal administration in the mouse.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Agmatine; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hyperalgesia; Indazoles; Injections, Spinal; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Spinal Cord

2005
TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-13, Volume: 26, Issue:37

    Topics: Administration, Oral; Analgesics; Animals; Arthralgia; Calcium; Capsaicin; Cell Line; Cells, Cultured; Central Nervous System; Disease Models, Animal; Humans; Hyperalgesia; Indazoles; Inflammation Mediators; Injections, Spinal; Male; Nociceptors; Pain; Pyridines; Rats; Rats, Sprague-Dawley; Sulfones; Treatment Outcome; TRPV Cation Channels; Urea

2006
Different roles of nitric oxide synthase-1 and -2 between herpetic and postherpetic allodynia in mice.
    Neuroscience, 2007, Dec-05, Volume: 150, Issue:2

    Topics: Animals; Dihydrolipoamide Dehydrogenase; Enzyme Inhibitors; Female; Ganglia, Spinal; Herpesvirus 1, Human; Hyperalgesia; Indazoles; Isothiuronium; Mice; Mice, Inbred C57BL; Neuralgia, Postherpetic; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nociceptors; Posterior Horn Cells; RNA, Messenger; Up-Regulation

2007
Blockade of joint inflammation and secondary hyperalgesia by L-NAME, a nitric oxide synthase inhibitor.
    Neuroreport, 1997, Mar-03, Volume: 8, Issue:4

    Topics: Analgesics; Animals; Arthritis; Carrageenan; Hyperalgesia; Indazoles; Inflammation; Injections, Intra-Articular; Isomerism; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

1997
Effects of intrathecal administration of nitric oxide synthase inhibitors on carrageenan-induced thermal hyperalgesia.
    British journal of pharmacology, 1999, Volume: 126, Issue:8

    Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hyperalgesia; Indazoles; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Long-Evans; Spinal Cord

1999
A neuronal nitric oxide synthase inhibitor 7-nitroindazole reduces the 5-HT1A receptor against 8-OH-DPAT-elicited hyperphagia in rats.
    European journal of pharmacology, 1999, Jul-02, Volume: 376, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Autoreceptors; Enzyme Inhibitors; Feeding Behavior; Hyperalgesia; Hypothalamus; Indazoles; Male; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists

1999
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.
    British journal of pharmacology, 2001, Volume: 134, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Spinal; Kynurenic Acid; Magnesium Sulfate; Male; Neurons; Nitric Oxide Synthase; Pain Measurement; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spine

2001