indazoles has been researched along with Adjuvant Arthritis in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Hu, T; Lu, Y; Qian, W; Shi, ZZ; Ye, C; Zhai, W; Zhou, M; Zhu, Y | 1 |
| Fan, H; Feng, J; Feng, T; Ge, L; Lu, Q; Pan, J; Ren, N; Song, G; Tian, R; Wang, L; Wang, S; Xiao, Y; Yi, X; Zhang, X | 1 |
| Anderson, K; Bai, C; Baltus, GA; Brandish, PE; Bungard, CJ; Bunting, P; Byford, A; Chiu, CS; Cicmil, M; Corcoran, H; Euler, D; Fisher, JE; Gambone, C; Hasbun-Manning, M; Hershey, JC; Kuklin, N; Landis, E; Lifsted, TQ; McElwee-Witmer, S; McIntosh, IS; Meissner, RS; Miao, J; Mitchell, HJ; Musselman, A; Schmidt, A; Shin, J; Szczerba, P; Thompson, CD; Tribouley, C; Vogel, RL; Warrier, S | 1 |
| Baculi, F; Bates, RJ; Bennett, B; Blease, K; Brown, H; Burnett, K; Celeridad, M; Chamberlain, P; Delgado, M; Ferguson, GD; Haelewyn, J; Hickman, M; Jackson, P; Jensen-Pergakes, K; LeBrun, L; Miyazawa, K; Nadolny, L; Nguyen, T; Packard, G; Pagarigan, B; Pierce, S; Plantevin-Krenitsky, V; Tang, Y; Tehrani, L; Torres, S; Xie, W; Xu, L | 1 |
| Cinci, L; Di Cesare Mannelli, L; Ghelardini, C; Maresca, M; Micheli, L; Pacini, A; Paola Giovannoni, M; Quinn, MT; Vergelli, C | 1 |
| Apicella, C; Guglielmotti, A; Mahalingam, S; Mangano, G; Rolph, MS; Rulli, NE; Suhrbier, A; Zaid, A | 1 |
| Chiang, PC; Kishore, NN; Thompson, DC | 1 |
| Casatti, CA; Costa, SK; Cruz-Rizzolo, RJ; Denadai-Souza, A; Ervolino, E; Muscará, MN; Teixeira, SA; Tesser-Viscaíno, SA | 1 |
| Akabane, H; Inagaki, N; Inami, Y; Miyagawa, N; Nagai, H; Nii, H; Tanaka, H; Togawa, M | 1 |
| Ashwell, MA; Borges-Marcucci, L; Chadwick, CC; Chippari, S; Eckert, A; Harnish, DC; Keith, JC; Kenney, T; Matelan, E; Moore, WJ; Mosyak, L; Solvibile, WR; Steffan, RJ; Trybulski, E; Xu, Z | 1 |
| Cravotto, G; Curini, M; Macchiarulo, A; Marcotullio, MC; Mattioli, L; Perfumi, M; Rismondo, F; Rosati, O | 1 |
| Bistocchi, GA; Boucherie, S; Brouilhet, H; De Meo, G; Jacquignon, P; Pedini, M; Rabaud, M; Ricci, A | 1 |
| Cheng, CY; Guglielmotti, A; Saso, L; Silvestrini, B; Zwain, I | 1 |
| Aquilini, L; Coletta, I; D'Onofrio, E; Guglielmotti, A; Milanese, C; Pinza, M | 1 |
| Eto, Y; Kawamura, K; Nagakura, M; Ota, T; Shimidzu, N; Wada, Y | 1 |
| Cheng, CY; Cioli, V; Guglielmotti, A; Luparini, MR; Saso, L; Silvestrini, B; Zwain, I | 1 |
| Catanese, B; Ciarniello, MG; Cioli, V; Durando, L; Fava, L; Guglielmotti, A; Luparini, MR; Martinelli, B; Silvestrini, B | 1 |
17 other study(ies) available for indazoles and Adjuvant Arthritis
| Article | Year |
|---|---|
Discovery and optimization of a potent and selective indazolamine series of IRAK4 inhibitors.
Topics: Amines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dose-Response Relationship, Drug; Drug Discovery; Haplorhini; Humans; Indazoles; Interleukin-1 Receptor-Associated Kinases; Lipopolysaccharides; Mice; Molecular Structure; Protein Kinase Inhibitors; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2021 |
Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis.
Topics: Adult; Aged; Animals; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Cytokines; Female; Hexokinase; Humans; Indazoles; Inflammation Mediators; Macrophages; Male; Mice, Inbred DBA; Middle Aged; RNA Interference; Synovial Membrane; Synoviocytes; THP-1 Cells | 2019 |
The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Benzamides; Cell Line, Tumor; Collagen; Cytokines; Dermatitis, Contact; Dogs; Edema; Female; HeLa Cells; Humans; Indazoles; Insulin; Lipopolysaccharides; Male; Methylprednisolone; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2014 |
A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
Topics: Animals; Arthritis, Experimental; Basophils; Cell Line; Collagen; Crystallography, X-Ray; Dose-Response Relationship, Drug; Edema; Eosinophils; Female; HEK293 Cells; Humans; Hypertension; Indazoles; Inflammation; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Neutropenia; Neutrophils; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Fc; Skin; Syk Kinase; Triazoles; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis.
Topics: Adjuvants, Immunologic; Animals; Arthralgia; Arthritis, Experimental; Freund's Adjuvant; Hindlimb; Hyperalgesia; Indazoles; Proteinase Inhibitory Proteins, Secretory; Pyrazoles; Rats; Rats, Sprague-Dawley; Tarsal Joints; Weight-Bearing | 2016 |
Amelioration of alphavirus-induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins.
Topics: Alphavirus; Alphavirus Infections; Animals; Antirheumatic Agents; Arthritis, Experimental; Cell Line; Disease Models, Animal; Down-Regulation; Humans; Indazoles; Macrophages; Mice; Mice, Inbred C57BL; Monocyte Chemoattractant Proteins; Muscle, Skeletal; Myositis; Propionates; RNA, Messenger | 2009 |
Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IkappaB kinase-2 (IKK-2) target safety and efficacy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Evaluation, Preclinical; Female; I-kappa B Kinase; Indazoles; Isonicotinic Acids; Male; Models, Biological; Rats; Rats, Inbred Lew; Rats, Wistar; Tumor Necrosis Factor-alpha | 2010 |
Putative antinociceptive action of nitric oxide in the caudal part of the spinal trigeminal nucleus during chronic carrageenan-induced arthritis in the rat temporomandibular joint.
Topics: Animals; Arthralgia; Arthritis, Experimental; Carrageenan; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Inflammation Mediators; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nociceptors; Pain Measurement; Pain Threshold; Posterior Horn Cells; Rats; Rats, Wistar; RNA, Messenger; Temporomandibular Joint Disorders; Trigeminal Caudal Nucleus | 2009 |
The effect of a newly synthesized indazole compound, TAS-3-124, on experimental autoimmune disease.
Topics: Acetamides; Animals; Arthritis, Experimental; Base Sequence; Cytokines; DNA Primers; Encephalomyelitis, Autoimmune, Experimental; Female; Hypersensitivity, Delayed; Indazoles; Male; Mice; Rats | 2004 |
Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Line; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Indazoles; Ligands; Mice; Mice, Inbred C57BL; Models, Molecular; NF-kappa B; Phenols; Rats; Rats, Inbred Lew; Receptors, Estrogen; Structure-Activity Relationship | 2004 |
Synthesis, docking studies and anti-inflammatory activity of 4,5,6,7-tetrahydro-2H-indazole derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase 2 Inhibitors; Foot; Freund's Adjuvant; Indazoles; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Pain Measurement; Rats; Stomach Ulcer; Structure-Activity Relationship | 2007 |
[N1-substituted 1H-indazole-3-ethyl carboxylates and 1H-indazole-3-hydroxamic acids].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carboxylic Acids; Hydroxamic Acids; Indazoles; Pyrazoles; Rats | 1981 |
Chronic inflammatory response in the rat can be blocked by bindarit.
Topics: Acute-Phase Proteins; alpha-Macroglobulins; Animals; Arthritis, Experimental; Clusterin; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Indazoles; Indomethacin; Male; Molecular Chaperones; Propionates; Proteins; Radioimmunoassay; Rats; Saposins; Serum Albumin | 1993 |
Amelioration of rat adjuvant arthritis by therapeutic treatment with bindarit, an inhibitor of MCP-1 and TNF-alpha production.
Topics: Animals; Arthritis, Experimental; Cell Line; Chemokine CCL2; Cytokines; Hindlimb; Humans; Immunity; Indazoles; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Osteoblasts; Ovalbumin; Propionates; Radiography; Rats; Tumor Necrosis Factor-alpha | 2002 |
Syntheses and antiinflammatory actions of 4,5,6,7-tetrahydroindazole-5-carboxylic acids.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema; Indazoles; Male; Pyrazoles; Rats; Stomach Ulcer; Structure-Activity Relationship | 1979 |
Abnormal glycosylation of hemopexin in arthritic rats can be blocked by bindarit.
Topics: Acute-Phase Reaction; Amino Acid Sequence; Animals; Arthritis, Experimental; Blood Proteins; Chromatography, High Pressure Liquid; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Freund's Adjuvant; Glycosylation; Hemopexin; Immunoblotting; Indazoles; Molecular Sequence Data; Propionates; Rats; Rats, Sprague-Dawley; Staining and Labeling | 1992 |
A new protein antidenaturant agent, bindarit, reduces secondary phase of adjuvant arthritis in rats.
Topics: Animals; Arthritis, Experimental; Blood Sedimentation; Cattle; Cytokines; Female; Hot Temperature; Indazoles; Indomethacin; Lipoxygenase; Male; Mice; Propionates; Prostaglandin-Endoperoxide Synthases; Protein Denaturation; Rats; Serum Albumin | 1992 |