Compounds > indazoles
Page last updated: 2024-08-21

indazoles and Acute Lung Injury

indazoles has been researched along with Acute Lung Injury in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bao, Y; Chen, G; Fu, L; Liu, Q; Liu, Z; Yan, H; Zhang, X; Zheng, H; Zheng, X1
Aki, A; Fukuda, T; Goto, R; Hashimoto, M; Kiho, T; Muramatsu, S; Tanaka, N; Ueda, K; Watanabe, K1
Chen, L; Chen, X; Fang, B; Li, C; Liang, G; Liu, Z; Luo, W; Wu, C; Yu, P; Zhang, Y1
Bansal, K; Connelly, R; Cox, RA; Enkhbaatar, P; Esechie, A; Hamahata, A; Hawkins, HK; Herndon, DN; Jonkam, C; Lange, M; Nakano, Y; Traber, DL; Traber, LD; von Borzyskowski, S1
Cox, RA; Enkhbaatar, P; Hamahata, A; Herndon, DN; Lange, M; Nakano, Y; Traber, DL; Traber, LD; Westphal, M1
Bai, C; Chen, C; Fang, X; Li, Y; Wang, D; Wang, X; Wang, Y; Zhao, X1
Cox, RA; Enkhbaatar, P; Hamahata, A; Hawkins, HK; Lange, M; Sakurai, H; Traber, DL; Traber, LD1
Jin, FG; Liu, W; Qian, GS1

Other Studies

8 other study(ies) available for indazoles and Acute Lung Injury

ArticleYear
A novel indazole derivative, compound Cyy-272, attenuates LPS-induced acute lung injury by inhibiting JNK phosphorylation.
    Toxicology and applied pharmacology, 2021, 10-01, Volume: 428

    Topics: Acute Lung Injury; Animals; Dose-Response Relationship, Drug; Indazoles; Lipopolysaccharides; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Phosphorylation; Protein Structure, Tertiary; RAW 264.7 Cells

2021
Discovery of DS28120313 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4,6-disubstituted indazole derivatives.
    Bioorganic & medicinal chemistry letters, 2017, 12-01, Volume: 27, Issue:23

    Topics: Acute Lung Injury; Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Hep G2 Cells; Hepcidins; Humans; Indazoles; Inflammation; Interleukin-6; Mice; Molecular Structure; Pyrazoles; Structure-Activity Relationship

2017
Discovery of 3-(Indol-5-yl)-indazole Derivatives as Novel Myeloid Differentiation Protein 2/Toll-like Receptor 4 Antagonists for Treatment of Acute Lung Injury.
    Journal of medicinal chemistry, 2019, 06-13, Volume: 62, Issue:11

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Drug Design; Indazoles; Lymphocyte Antigen 96; Mice; Models, Molecular; Protein Conformation; Toll-Like Receptor 4

2019
Combined neuronal and inducible nitric oxide synthase inhibition in ovine acute lung injury.
    Critical care medicine, 2009, Volume: 37, Issue:1

    Topics: Acute Lung Injury; Animals; Enzyme Inhibitors; Female; Imidazoles; Indazoles; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Piperazines; Pyrimidines; Sheep

2009
Beneficial effects of concomitant neuronal and inducible nitric oxide synthase inhibition in ovine burn and inhalation injury.
    Shock (Augusta, Ga.), 2011, Volume: 35, Issue:6

    Topics: Acute Lung Injury; Animals; Burns; Capillary Permeability; Female; Heart Rate; Imidazoles; Indazoles; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrogen Oxides; Piperazines; Pulmonary Gas Exchange; Pyrimidines; Respiratory Distress Syndrome; Sheep, Domestic; Smoke Inhalation Injury

2011
Preventive and therapeutic effects of phosphoinositide 3-kinase inhibitors on acute lung injury.
    Chest, 2011, Volume: 140, Issue:2

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Chromones; Epithelial Cells; Indazoles; Leukocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Sulfonamides

2011
Direct delivery of low-dose 7-nitroindazole into the bronchial artery attenuates pulmonary pathophysiology after smoke inhalation and burn injury in an ovine model.
    Shock (Augusta, Ga.), 2011, Volume: 36, Issue:6

    Topics: Acute Lung Injury; Animals; Bronchial Arteries; Burns; Female; Indazoles; Lung; Nitric Oxide Synthase Type I; Sheep; Smoke Inhalation Injury

2011
[Effects of 7-nitroindazole on smoke inhalation pulmonary injury].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2007, Volume: 19, Issue:4

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Indazoles; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Random Allocation; Rats; Rats, Sprague-Dawley; Smoke Inhalation Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2007