Page last updated: 2024-10-29

indapamide and Metabolic Syndrome

indapamide has been researched along with Metabolic Syndrome in 10 studies

Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"To evaluate effects of 6-month therapy with losartan in combination with indapamide on a clinical course, immunological, metabolic parameters, left ventricular function, exercise tolerance and quality of life in patients with coronary heart disease (CHD) associated with metabolic syndrome (MS)."9.14[Immunomodulating, metabolic and cardioprotective effects of AT1-angiotensin receptors blocker losartan in patients with coronary heart disease and type 2 diabetes mellitus]. ( Bolotskaia, LA; Derbeneva, NV; Frants, MV; Kuznetsova, AV; Lukinov, AV; Maianskaia, SD; Shilov, SN; Stepacheva, TA; Tepliakov, AT; Vdovina, TV, 2009)
"The aim of the observational pharmaco-epidemiological study Optimax II was to seek whether the pre-existence of a metabolic syndrome (MS) defined by the NCEP-ATP III criteria impacts blood pressure (BP) control in hypertensive patients receiving a fixed perindopril/indapamide combination therapy."9.13Blood pressure normalization by fixed perindopril/indapamide combination in hypertensive patients with or without associate metabolic syndrome: results of the OPTIMAX 2 study. ( Guillausseau, PJ; Lameira, D; Mourad, JJ, 2008)
"To assess real-life effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in patients with hypertension (HT) and type 2 diabetes mellitus (T2DM), obesity and/or metabolic syndrome (MetS)."9.12Beneficial Effects of a Perindopril/Indapamide Single-Pill Combination in Hypertensive Patients with Diabetes and/or Obesity or Metabolic Syndrome: A Post Hoc Pooled Analysis of Four Observational Studies. ( Brzozowska-Villatte, R; De Champvallins, M; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021)
"Therapy with the use of a fixed combination of perindopril and indapamide was prescribed to 22 patients with metabolic syndrome and I - II degree hypertension for 16 weeks."9.12[Effect of a fixed combination of perindopril and indapamide on 24-hour blood pressure profile, morpho-functional parameters of the heart, heart rate variability, functional state of the kidney, and quality of life in patients with arterial hypertension c ( Statsenko, ME; Zemlianskaia, MM, 2007)
"To study ways of realization of pleiotropic effects of treatment with low-dose combination of perindopril arginine with indapamide in hypertensive patients with metabolic syndrome (MS)."7.77[Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome]. ( , 2011)
"To evaluate effects of 6-month therapy with losartan in combination with indapamide on a clinical course, immunological, metabolic parameters, left ventricular function, exercise tolerance and quality of life in patients with coronary heart disease (CHD) associated with metabolic syndrome (MS)."5.14[Immunomodulating, metabolic and cardioprotective effects of AT1-angiotensin receptors blocker losartan in patients with coronary heart disease and type 2 diabetes mellitus]. ( Bolotskaia, LA; Derbeneva, NV; Frants, MV; Kuznetsova, AV; Lukinov, AV; Maianskaia, SD; Shilov, SN; Stepacheva, TA; Tepliakov, AT; Vdovina, TV, 2009)
"The aim of the observational pharmaco-epidemiological study Optimax II was to seek whether the pre-existence of a metabolic syndrome (MS) defined by the NCEP-ATP III criteria impacts blood pressure (BP) control in hypertensive patients receiving a fixed perindopril/indapamide combination therapy."5.13Blood pressure normalization by fixed perindopril/indapamide combination in hypertensive patients with or without associate metabolic syndrome: results of the OPTIMAX 2 study. ( Guillausseau, PJ; Lameira, D; Mourad, JJ, 2008)
"To assess real-life effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in patients with hypertension (HT) and type 2 diabetes mellitus (T2DM), obesity and/or metabolic syndrome (MetS)."5.12Beneficial Effects of a Perindopril/Indapamide Single-Pill Combination in Hypertensive Patients with Diabetes and/or Obesity or Metabolic Syndrome: A Post Hoc Pooled Analysis of Four Observational Studies. ( Brzozowska-Villatte, R; De Champvallins, M; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021)
"Therapy with the use of a fixed combination of perindopril and indapamide was prescribed to 22 patients with metabolic syndrome and I - II degree hypertension for 16 weeks."5.12[Effect of a fixed combination of perindopril and indapamide on 24-hour blood pressure profile, morpho-functional parameters of the heart, heart rate variability, functional state of the kidney, and quality of life in patients with arterial hypertension c ( Statsenko, ME; Zemlianskaia, MM, 2007)
"To study ways of realization of pleiotropic effects of treatment with low-dose combination of perindopril arginine with indapamide in hypertensive patients with metabolic syndrome (MS)."3.77[Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome]. ( , 2011)
"Seventy five patients with metabolic syndrome aged 40-59 years were included into an open study with parallel groups in which the following combinations of lipid lowering and antihypertensive drugs were used for sweeksinch: atorvastatin + perindopril (n=17, group 1); simvastatin + atenolol (n=17, group 2); fenofibrate + atenolol (n=21, group 3), and simvastatin + indapamide (n=20, group 4)."3.72[Effect of combined antihypertensive and lipid lowering therapy on the level of coronary risk and tissue insulin resistance in patients with metabolic syndrome]. ( Khadipash, LA; Kiseleva, NV; Kosmatova, OV; Mamedov, MN; Oganov, RG; Perova, NV, 2003)
"Determination of the effectiveness and safety of different dosing regimens during the day (in the morning or at bedtime) combination therapy including azilsartan medoxomil in patients with essential hypertension and metabolic syndrome (MS)."1.43[Hronotherapy Aspects of Efficiency Azilsartan Medoxomil in Combination Therapy in Patients With Hypertension and Metabolic Syndrome]. ( Fendrikova, AV; Sirotenko, DV; Skibitskiy, AV; Skibitskiy, VV, 2016)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Farsang, C1
Dézsi, CA1
Brzozowska-Villatte, R1
De Champvallins, M1
Glezer, M1
Karpov, Y1
Skibitskiy, VV1
Fendrikova, AV1
Sirotenko, DV1
Skibitskiy, AV1
Mourad, JJ1
Lameira, D1
Guillausseau, PJ1
Tepliakov, AT1
Maianskaia, SD1
Bolotskaia, LA1
Vdovina, TV1
Stepacheva, TA1
Kuznetsova, AV1
Lukinov, AV1
Derbeneva, NV1
Frants, MV1
Shilov, SN1
Efimova, IIu1
Kalashnikova, TP1
Lishmanov, IuB1
Mamedov, MN1
Perova, NV1
Kosmatova, OV1
Khadipash, LA1
Kiseleva, NV1
Oganov, RG1
Trusov, VV1
Filimonov, MA1
Aksenov, KV1
Sergienko, VB1
Gornostaev, VV1
Bugriĭ, ME1
Mychka, VB1
Chazova, IE1
Statsenko, ME1
Zemlianskaia, MM1

Reviews

1 review available for indapamide and Metabolic Syndrome

ArticleYear
Beneficial Effects of a Perindopril/Indapamide Single-Pill Combination in Hypertensive Patients with Diabetes and/or Obesity or Metabolic Syndrome: A Post Hoc Pooled Analysis of Four Observational Studies.
    Advances in therapy, 2021, Volume: 38, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Drug Combinations; Humans;

2021

Trials

5 trials available for indapamide and Metabolic Syndrome

ArticleYear
Blood pressure normalization by fixed perindopril/indapamide combination in hypertensive patients with or without associate metabolic syndrome: results of the OPTIMAX 2 study.
    Vascular health and risk management, 2008, Volume: 4, Issue:2

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics;

2008
[Immunomodulating, metabolic and cardioprotective effects of AT1-angiotensin receptors blocker losartan in patients with coronary heart disease and type 2 diabetes mellitus].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:3

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiotonic Agents; C

2009
[The impact of antihypertensive therapy on cerebral hemodynamics in patients with metabolic syndrome].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:8

    Topics: Antihypertensive Agents; Biological Availability; Blood Pressure Monitoring, Ambulatory; Brain; Cere

2012
[Correction of endothelial dysfunction by noliprel in patients with metabolic syndrome].
    Kardiologiia, 2005, Volume: 45, Issue:5

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Combinations; Endothel

2005
[Effect of a fixed combination of perindopril and indapamide on 24-hour blood pressure profile, morpho-functional parameters of the heart, heart rate variability, functional state of the kidney, and quality of life in patients with arterial hypertension c
    Kardiologiia, 2007, Volume: 47, Issue:8

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertensi

2007

Other Studies

4 other studies available for indapamide and Metabolic Syndrome

ArticleYear
[Hronotherapy Aspects of Efficiency Azilsartan Medoxomil in Combination Therapy in Patients With Hypertension and Metabolic Syndrome].
    Kardiologiia, 2016, Volume: 56, Issue:10

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Benzimida

2016
[Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome].
    Terapevticheskii arkhiv, 2011, Volume: 83, Issue:10

    Topics: Antihypertensive Agents; Comorbidity; Drug Administration Schedule; Drug Therapy, Combination; Femal

2011
[Effect of combined antihypertensive and lipid lowering therapy on the level of coronary risk and tissue insulin resistance in patients with metabolic syndrome].
    Kardiologiia, 2003, Volume: 43, Issue:3

    Topics: Adult; Antihypertensive Agents; Atenolol; Atorvastatin; Blood Pressure; Cholesterol, HDL; Cholestero

2003
[Cerebral and myocardial perfusion in patients with arterial hypertension and metabolic syndrome after monotherapy with combined drug noliprel].
    Kardiologiia, 2006, Volume: 46, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Brain; Cerebrovascular Circulation; Coronary Circulation;

2006