indapamide has been researched along with Left Ventricular Hypertrophy in 41 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this prospective open-label study, 92 patients with essential hypertension were randomized to treatment with a TFC of perindopril/indapamide/amlodipine at different doses or a triple free combination therapy (FCT) including ACEI/diuretic/CCB." | 9.30 | Long-term effect of the perindopril/indapamide/amlodipine single-pill combination on left ventricular hypertrophy in outpatient hypertensive subjects. ( Lenti, S; Mazza, A; Rigatelli, G; Rossetti, C; Rubello, D; Schiavon, L; Torin, G; Townsend, DM, 2019) |
| "5 mg and enalapril 20 mg at reducing left ventricular mass index (LVMI) in hypertensive patients with left ventricular hypertrophy (LVH)." | 9.09 | Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study. ( Chastang, C; de Leeuw, PW; Degaute, JP; Dubourg, O; Gosse, P; Guéret, P; Karpov, Y; Motz, W; Palma-Gamiz, JL; Pessina, A; Sheridan, DJ; Zannad, F, 2000) |
| "This report describes the effects of indapamide versus transdermal clonidine on left ventricular hypertrophy (LVH) in hypertensive diabetic patients." | 9.08 | Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. ( Berk, LS; Tan, LG; Tan, SA, 1996) |
| " The present multicenter open study was designed to test the effects of indapamide, a widely used nonthiazide diuretic, on LVH in patients with essential hypertension." | 9.08 | Regression of left ventricular hypertrophy in patients with essential hypertension. Results of 6 month treatment with indapamide. ( Balazovjech, I; Barrandon, S; Brault, Y; Brown, R; Curry, CL; de Cordoüe, A; Galinier, F; Guez, D; Honos, G; Mariani, M; Olivan, J; Robinson, H; Ruddy, TD; Sami, M; Touzek, F, 1996) |
| "5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)." | 9.07 | Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 8.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "The fixed low-dose combination of the ACE inhibitor perindopril and the non-thiazide diuretic indapamide has been evaluated in the management of patients with mild to moderate hypertension." | 8.81 | Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. ( Cheer, SM; Goa, KL; Matheson, AJ, 2001) |
| "The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis." | 7.77 | The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011) |
| "The effects of indapamide, a thiazide-like diuretic, and captopril, an angiotensin-converting enzyme inhibitor, on spontaneous hypertension and the development of left ventricular hypertrophy (LVH), nitric oxide generation and oxidant status were investigated." | 7.75 | Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension. ( Jendekova, L; Paulis, L; Pechanova, O; Simko, F; Sladkova, M; Vranková, S, 2009) |
| "Perindopril/indapamide treatment reduced 24-hour and daytime systolic BP (SBP) and pulse pressure (PP) significantly more than enalapril treatment (p < 0." | 6.73 | Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy. ( Asmar, R; De Leeuws, PW; Garcia-Puig, J; Gosse, P; Karpov, YA; Magometschniggs, D; Matos, L; Schmieder, R, 2007) |
| " Once daily dosing of the preparation provided high level of compliance of patients with treatment." | 6.72 | [Effect of twelve-month combined therapy with perindopril and indapamide on the level of blood pressure and left ventricular hypertrophy in patients with hypertensive disease]. ( Alekhin, MN; Chumakova, OS; Larina, VN; Sidorenko, BA; Timofeeva, LA; Ugriumov, MO, 2006) |
| "The PICXEL study is designed to evaluate the effects of long-term administration of very low-dose combination perindopril 2 mg/indapamide 0." | 6.70 | Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design. ( Amouyel, P; Asmar, R; Dahlöf, B; De Leeuw, PW; De Simone, G; Degaute, JP; Dubourg, O; García Puig, J; Gosse, P; Guéret, P; Karpov, Y; Le Heuzey, JY; Magometschnigg, D; Matos, L; Nieminen, M; Schmieder, R, 2002) |
| "Left ventricular hypertrophy is a major risk factor for cardiovascular morbidity and mortality." | 6.39 | Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis. ( Carey, PA; de Cordoue, A; Guez, D; Sheridan, DJ, 1996) |
| "In this prospective open-label study, 92 patients with essential hypertension were randomized to treatment with a TFC of perindopril/indapamide/amlodipine at different doses or a triple free combination therapy (FCT) including ACEI/diuretic/CCB." | 5.30 | Long-term effect of the perindopril/indapamide/amlodipine single-pill combination on left ventricular hypertrophy in outpatient hypertensive subjects. ( Lenti, S; Mazza, A; Rigatelli, G; Rossetti, C; Rubello, D; Schiavon, L; Torin, G; Townsend, DM, 2019) |
| " The PICXEL study compared the efficacy of a strategy based on first-line combination with perindopril/indapamide versus monotherapy with enalapril in reducing left ventricular hypertrophy (LVH) in hypertensive patients." | 5.11 | Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study. ( Dahlöf, B; De Leeuw, PW; de Simone, G; Degaute, JP; Dubourg, O; García-Puig, J; Gosse, P; Guéret, P; Karpov, Y; Magometschnigg, D; Matos, L; Schmieder, R, 2005) |
| "In the treatment of hypertension in subjects of African origins, although hydrochlorothiazide (HCTZ) is not as effective as calcium channel blockers, indapamide is superior to HCTZ." | 5.11 | Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry. ( Candy, GP; Essop, MR; Hlatshwayo, NM; Kachope, J; Libhaber, CD; Libhaber, EN; Norton, GR; Puane, MO; Sareli, P; Sliwa, K; Woodiwiss, AJ, 2004) |
| "5 mg and enalapril 20 mg at reducing left ventricular mass index (LVMI) in hypertensive patients with left ventricular hypertrophy (LVH)." | 5.09 | Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study. ( Chastang, C; de Leeuw, PW; Degaute, JP; Dubourg, O; Gosse, P; Guéret, P; Karpov, Y; Motz, W; Palma-Gamiz, JL; Pessina, A; Sheridan, DJ; Zannad, F, 2000) |
| "This report describes the effects of indapamide versus transdermal clonidine on left ventricular hypertrophy (LVH) in hypertensive diabetic patients." | 5.08 | Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. ( Berk, LS; Tan, LG; Tan, SA, 1996) |
| " The present multicenter open study was designed to test the effects of indapamide, a widely used nonthiazide diuretic, on LVH in patients with essential hypertension." | 5.08 | Regression of left ventricular hypertrophy in patients with essential hypertension. Results of 6 month treatment with indapamide. ( Balazovjech, I; Barrandon, S; Brault, Y; Brown, R; Curry, CL; de Cordoüe, A; Galinier, F; Guez, D; Honos, G; Mariani, M; Olivan, J; Robinson, H; Ruddy, TD; Sami, M; Touzek, F, 1996) |
| "The LIVE (Left Ventricular Hypertrophy: Indapamide Versus Enalapril) study is an ongoing multicenter, double-blind, controlled study of regression of echocardiographic left ventricular mass index in hypertensive patients with left ventricular hypertrophy (left ventricular mass indexes > 100 g/m2 for women and > 120 g/m2 for men) treated for 1 year with 1." | 5.08 | Centralized echocardiogram quality control in a multicenter study of regression of left ventricular hypertrophy in hypertension. ( Barrandon, S; Beauchet, A; de Cordoüe, A; Dubourg, O; Gosse, P; Guéret, P; Guez, D, 1998) |
| "5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)." | 5.07 | Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 4.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "The fixed low-dose combination of the ACE inhibitor perindopril and the non-thiazide diuretic indapamide has been evaluated in the management of patients with mild to moderate hypertension." | 4.81 | Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. ( Cheer, SM; Goa, KL; Matheson, AJ, 2001) |
| "Patients with echocardiographic left ventricular hypertrophy at baseline (n = 124) showed greater reduction of left ventricular mass index with Per/Ind (-11." | 3.80 | [Arterial stiffness, wave reflections and myocardial protection: the REASON project]. ( London, GM, 2003) |
| "The LIVE study (Left Ventricular Hypertrophy Regression: Indapamide Versus Enalapril) is a European, prospective, double-blind, randomised, controlled trial aimed to compare the efficacy of indapamide 1." | 3.79 | Left ventricular hypertrophy regression: the LIVE trial. ( Sheridan, DJ, 1999) |
| "The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis." | 3.77 | The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011) |
| "The effects of indapamide, a thiazide-like diuretic, and captopril, an angiotensin-converting enzyme inhibitor, on spontaneous hypertension and the development of left ventricular hypertrophy (LVH), nitric oxide generation and oxidant status were investigated." | 3.75 | Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension. ( Jendekova, L; Paulis, L; Pechanova, O; Simko, F; Sladkova, M; Vranková, S, 2009) |
| "Perindopril/indapamide treatment reduced 24-hour and daytime systolic BP (SBP) and pulse pressure (PP) significantly more than enalapril treatment (p < 0." | 2.73 | Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy. ( Asmar, R; De Leeuws, PW; Garcia-Puig, J; Gosse, P; Karpov, YA; Magometschniggs, D; Matos, L; Schmieder, R, 2007) |
| " Once daily dosing of the preparation provided high level of compliance of patients with treatment." | 2.72 | [Effect of twelve-month combined therapy with perindopril and indapamide on the level of blood pressure and left ventricular hypertrophy in patients with hypertensive disease]. ( Alekhin, MN; Chumakova, OS; Larina, VN; Sidorenko, BA; Timofeeva, LA; Ugriumov, MO, 2006) |
| "Large trials on left ventricular hypertrophy (LVH) regression are indispensable to allow accurate evaluation of the different classes of treatments." | 2.71 | Regression of left ventricular hypertrophy with echocardiography: some lessons from the LIVE study. ( Dubourg, O; Gosse, P; Gueret, P, 2003) |
| "The PICXEL study is designed to evaluate the effects of long-term administration of very low-dose combination perindopril 2 mg/indapamide 0." | 2.70 | Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design. ( Amouyel, P; Asmar, R; Dahlöf, B; De Leeuw, PW; De Simone, G; Degaute, JP; Dubourg, O; García Puig, J; Gosse, P; Guéret, P; Karpov, Y; Le Heuzey, JY; Magometschnigg, D; Matos, L; Nieminen, M; Schmieder, R, 2002) |
| "In patients with type 2 diabetes, left ventricular hypertrophy is mainly due to high blood pressure, but also to reduced elasticity of the large vessels, defective vasomotricity and dysfunction of the arterial endothelium." | 2.70 | [Management of hypertensive patients with left ventricular hypertrophy]. ( Ambrosioni, E, 2002) |
| "05) in the 15 patients with left ventricular hypertrophy." | 2.69 | Effects of delapril in combination with indapamide on blood pressure and left ventricular mass in elderly hypertensive patients. ( Acanfora, D; Furgi, G; Iannuzzi, GL; Lowenthal, DT; Nicolino, A; Papa, A; Picone, C; Rengo, F; Trojano, L, 1998) |
| "Regression of left ventricular hypertrophy (LVH) at the background of hypotensive therapy is associated with additional lowering of cardiovascular risk." | 2.43 | [Hypertrophy of left ventricular myocardium as modifiable risk factor: novel possibilities of correction]. ( Bulkina, OS; Karpov, IuA; Talitskiĭ, KA, 2006) |
| "Indapamide has a dual mechanism of action: diuretic effect at the level of the distal tubule in the kidney and a direct vascular effect, both of which contribute to the antihypertensive efficacy of the drug." | 2.43 | An overview of the pharmacology and clinical efficacy of indapamide sustained release. ( Bataillard, A; McIntyre, H; Sassard, J, 2005) |
| "Hypertension is a major influence on the development of LVH." | 2.43 | Ventricular hypertrophy and hypertension: prognostic elements and implications for management. ( Devereux, RB; Krauser, DG, 2006) |
| " Diuretics used at lower dosage than in the past are effective in reducing morbidity and mortality and continue to be drugs of first choice in the treatment of hypertension." | 2.42 | Clinical role of Natrilix SR in the treatment of at-risk hypertensive patients. ( Ambrosioni, E; Veronesi, M, 2003) |
| "The treatment with indapamide SR resulted in a better or equivalent control of SBP than treatment with a standard dose of a true thiazide diuretic (hydrochlorothiazide), a calcium channel blocker (amlodipine), and an angiotensin-converting enzyme inhibitor (enalapril)." | 2.42 | Efficacy of indapamide 1.5 mg, sustained release, in the lowering of systolic blood pressure. ( London, GM, 2004) |
| "Left ventricular hypertrophy is a major risk factor for cardiovascular morbidity and mortality." | 2.39 | Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis. ( Carey, PA; de Cordoue, A; Guez, D; Sheridan, DJ, 1996) |
| "Factors that must be considered for the treatment of hypertension in patients, particularly with type 2 diabetes." | 1.31 | [Reflexion of French experts on the key points of the symposium]. ( Dubourg, O; Forette, F; Hanon, O; Mallion, JM; Marre, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (21.95) | 18.2507 |
| 2000's | 24 (58.54) | 29.6817 |
| 2010's | 8 (19.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mazza, A | 1 |
| Townsend, DM | 1 |
| Schiavon, L | 1 |
| Torin, G | 1 |
| Lenti, S | 1 |
| Rossetti, C | 1 |
| Rigatelli, G | 1 |
| Rubello, D | 1 |
| Roush, GC | 2 |
| Abdelfattah, R | 2 |
| Song, S | 2 |
| Kostis, JB | 2 |
| Ernst, ME | 2 |
| Sica, DA | 2 |
| Tadic, M | 1 |
| Cuspidi, C | 1 |
| Kuusela, PJ | 1 |
| Vranková, S | 2 |
| Jendekova, L | 2 |
| Paulis, L | 1 |
| Sladkova, M | 2 |
| Simko, F | 1 |
| Pechanova, O | 3 |
| Linchak, RM | 1 |
| Ishikawa, J | 1 |
| Eguchi, K | 1 |
| Hoshide, S | 1 |
| Shimada, K | 1 |
| Kario, K | 1 |
| Hlavačková, L | 1 |
| Janega, P | 1 |
| Babál, P | 1 |
| Gosse, P | 6 |
| Dubourg, O | 6 |
| Guéret, P | 5 |
| De Simone, G | 2 |
| Schmieder, R | 3 |
| De Leeuw, PW | 4 |
| Degaute, JP | 3 |
| García Puig, J | 1 |
| Karpov, Y | 3 |
| Magometschnigg, D | 2 |
| Matos, L | 3 |
| Amouyel, P | 1 |
| Asmar, R | 2 |
| Le Heuzey, JY | 1 |
| Nieminen, M | 1 |
| Dahlöf, B | 2 |
| Ambrosioni, E | 2 |
| Mallion, JM | 2 |
| Forette, F | 1 |
| Hanon, O | 1 |
| Marre, M | 1 |
| Rakić, D | 1 |
| Rumboldt, Z | 1 |
| Bagatin, J | 1 |
| Polić, S | 1 |
| Sheridan, DJ | 3 |
| London, GM | 3 |
| Veronesi, M | 1 |
| Kisliak, OA | 1 |
| Storozhakov, GI | 1 |
| Alieva, AM | 1 |
| Kasatova, TB | 1 |
| Kopelev, AM | 1 |
| Potapova, LS | 1 |
| Libhaber, EN | 1 |
| Libhaber, CD | 1 |
| Candy, GP | 1 |
| Sliwa, K | 1 |
| Kachope, J | 1 |
| Hlatshwayo, NM | 1 |
| Puane, MO | 1 |
| Woodiwiss, AJ | 1 |
| Norton, GR | 1 |
| Essop, MR | 1 |
| Sareli, P | 1 |
| Lokhandwala, Y | 1 |
| Damle, A | 1 |
| de Luca, N | 3 |
| Asmar, RG | 1 |
| O'Rourke, MF | 2 |
| Safar, ME | 2 |
| O'Brien, E | 1 |
| Rahn, KH | 1 |
| Trimarco, B | 1 |
| Romero, R | 1 |
| Hitzenberger, G | 1 |
| Battegay, E | 1 |
| Duprez, D | 1 |
| Sever, P | 1 |
| García-Puig, J | 2 |
| Sassard, J | 1 |
| Bataillard, A | 1 |
| McIntyre, H | 1 |
| Timofeeva, LA | 1 |
| Alekhin, MN | 1 |
| Ugriumov, MO | 1 |
| Chumakova, OS | 1 |
| Larina, VN | 1 |
| Sidorenko, BA | 1 |
| Bulkina, OS | 1 |
| Talitskiĭ, KA | 1 |
| Karpov, IuA | 1 |
| Krauser, DG | 1 |
| Devereux, RB | 1 |
| Kojsová, S | 1 |
| Karpov, YA | 1 |
| De Leeuws, PW | 1 |
| Magometschniggs, D | 1 |
| Kokkinos, PF | 1 |
| Narayan, P | 1 |
| Colleran, JA | 1 |
| Pittaras, A | 1 |
| Notargiacomo, A | 1 |
| Reda, D | 1 |
| Papademetriou, V | 1 |
| Senior, R | 1 |
| Imbs, JL | 1 |
| Bory, M | 1 |
| Amabile, G | 1 |
| Denis, B | 1 |
| Zannad, F | 2 |
| Marchegiano, R | 1 |
| Lahiri, A | 1 |
| Raftery, EB | 1 |
| Balazovjech, I | 2 |
| Tousek, J | 1 |
| Guery, O | 1 |
| Dúbrava, P | 1 |
| Uhliar, R | 1 |
| Carey, PA | 1 |
| de Cordoue, A | 3 |
| Guez, D | 3 |
| Tan, SA | 1 |
| Berk, LS | 1 |
| Tan, LG | 1 |
| Curry, CL | 1 |
| Robinson, H | 1 |
| Brown, R | 1 |
| Olivan, J | 1 |
| Sami, M | 1 |
| Honos, G | 1 |
| Ruddy, TD | 1 |
| Touzek, F | 1 |
| Galinier, F | 1 |
| Mariani, M | 1 |
| Barrandon, S | 2 |
| Brault, Y | 1 |
| Beauchet, A | 1 |
| Acanfora, D | 1 |
| Lowenthal, DT | 1 |
| Furgi, G | 1 |
| Trojano, L | 1 |
| Picone, C | 1 |
| Nicolino, A | 1 |
| Iannuzzi, GL | 1 |
| Papa, A | 1 |
| Rengo, F | 1 |
| Böcker, W | 1 |
| Hupf, H | 1 |
| Grimm, D | 1 |
| Kurzidim, K | 1 |
| Schunkert, H | 1 |
| Palma-Gamiz, JL | 1 |
| Pessina, A | 1 |
| Motz, W | 1 |
| Chastang, C | 1 |
| Matheson, AJ | 1 |
| Cheer, SM | 1 |
| Goa, KL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for indapamide and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Diuretics, Potassium Spari | 2018 |
Hydrochlorothiazide vs chlorthalidone, indapamide, and potassium-sparing/hydrochlorothiazide diuretics for reducing left ventricular hypertrophy: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics, Potassium Sparing; Drug Therapy, | 2018 |
Left ventricular hypertrophy regression: the LIVE trial.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Enalapril; Humans; Hypertrophy, Left Ventricular; | 1999 |
[Arterial stiffness, wave reflections and myocardial protection: the REASON project].
Topics: Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diastole; Drug Combinations; Humans; Hy | 2003 |
Clinical role of Natrilix SR in the treatment of at-risk hypertensive patients.
Topics: Delayed-Action Preparations; Humans; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Risk F | 2003 |
Efficacy of indapamide 1.5 mg, sustained release, in the lowering of systolic blood pressure.
Topics: Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diabetes Me | 2004 |
An overview of the pharmacology and clinical efficacy of indapamide sustained release.
Topics: Albuminuria; Antihypertensive Agents; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Eviden | 2005 |
[Hypertrophy of left ventricular myocardium as modifiable risk factor: novel possibilities of correction].
Topics: Angiotensin-Converting Enzyme Inhibitors; Diuretics; Drug Therapy, Combination; Humans; Hypertrophy, | 2006 |
Ventricular hypertrophy and hypertension: prognostic elements and implications for management.
Topics: Adrenergic Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convert | 2006 |
Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis.
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Female; Humans; H | 1996 |
Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension.
Topics: Adult; Age Factors; Aged; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; | 2001 |
21 trials available for indapamide and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Long-term effect of the perindopril/indapamide/amlodipine single-pill combination on left ventricular hypertrophy in outpatient hypertensive subjects.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Follow | 2019 |
Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Double-Blind Method; Drug Combina | 2002 |
[Management of hypertensive patients with left ventricular hypertrophy].
Topics: Adrenergic alpha-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent | 2002 |
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventr | 2002 |
Left ventricular hypertrophy regression: the LIVE trial.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Enalapril; Humans; Hypertrophy, Left Ventricular; | 1999 |
Regression of left ventricular hypertrophy with echocardiography: some lessons from the LIVE study.
Topics: Antihypertensive Agents; Delayed-Action Preparations; Double-Blind Method; Echocardiography; Enalapr | 2003 |
[Arterial stiffness, wave reflections and myocardial protection: the REASON project].
Topics: Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diastole; Drug Combinations; Humans; Hy | 2003 |
Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry.
Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black Pe | 2004 |
Selective reduction of cardiac mass and central blood pressure on low-dose combination perindopril/indapamide in hypertensive subjects.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Carotid Arteries; D | 2004 |
Regression of left ventricular mass in hypertensive patients treated with perindopril/indapamide as a first-line combination: the REASON echocardiography study.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Drug Therapy, Combi | 2004 |
Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination | 2005 |
[Effect of twelve-month combined therapy with perindopril and indapamide on the level of blood pressure and left ventricular hypertrophy in patients with hypertensive disease].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Comorbidity; Diuretics; Drug Therapy, Combina | 2006 |
Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, | 2007 |
Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Combined Modality Therapy; Exerc | 1995 |
Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Enalapril; Female; France; Humans; Hydro | 1993 |
[Regression of hypertrophy of the left ventricle in patients with hypertension after 6-month treatment with Fludex].
Topics: Blood Pressure; Cardiac Volume; Echocardiography; Electrocardiography; Female; Humans; Hypertension; | 1993 |
Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients.
Topics: Administration, Cutaneous; Adult; Aged; Antihypertensive Agents; Clonidine; Cross-Over Studies; Diab | 1996 |
Regression of left ventricular hypertrophy in patients with essential hypertension. Results of 6 month treatment with indapamide.
Topics: Adult; Aged; Blood Pressure; Diuretics; Echocardiography; Female; Humans; Hypertension; Hypertrophy, | 1996 |
Centralized echocardiogram quality control in a multicenter study of regression of left ventricular hypertrophy in hypertension.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Echocardiography; Enalapril; Female; Humans; Hy | 1998 |
Effects of delapril in combination with indapamide on blood pressure and left ventricular mass in elderly hypertensive patients.
Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Age | 1998 |
Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Echocardiography; Enalapr | 2000 |
11 other studies available for indapamide and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Diuretics and left ventricular hypertrophy regression: The relationship that we commonly forget.
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hyper | 2018 |
Interventricular vessel of the heart and diuretics.
Topics: Chlorthalidone; Diuretics; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, | 2019 |
Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Femoral Artery; Hyperten | 2009 |
[Comparative efficacy of a fixed combination perindopril/ indapamide in arterial hypertension patients of various sexes and ages].
Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P | 2010 |
Relationship between the change in left ventricular hypertrophy and asleep blood pressure after sodium restriction and/or diuretic treatment.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diet, Sodium-R | 2011 |
The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat.
Topics: Animals; Captopril; Collagen Type I; Collagen Type III; Fibrosis; Hypertension; Hypertrophy, Left Ve | 2011 |
[Reflexion of French experts on the key points of the symposium].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; | 2002 |
[Results of monotherapy with retard formulation of indapamide of elderly patients with isolated systolic hypertension and left ventricular hypertrophy].
Topics: Aged; Aged, 80 and over; Delayed-Action Preparations; Diuretics; Electrocardiography; Female; Humans | 2003 |
Left ventricular hypertrophy in hypertensive patients in Indian primary care: prevalence and effect of treatment with sustained release indapamide.
Topics: Antihypertensive Agents; Delayed-Action Preparations; Echocardiography; Electrocardiography; Female; | 2004 |
Chronic and acute effects of different antihypertensive drugs on femoral artery relaxation of L-NAME hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pre | 2007 |
Effects of indapamide in rats with pressure overload left ventricular hypertrophy.
Topics: Animals; Antihypertensive Agents; Aortic Valve Stenosis; Biomarkers; Blood Pressure; Creatinine; Hea | 2000 |