indapamide has been researched along with Hypertension in 640 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this non-interventional post-marketing clinical trial was to analyze the antihypertensive effect and safety of a fixed combination of perindopril and indapamide in the treatment of unregulated essential hypertension." | 9.51 | The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study. ( Boloban, A; Džananović Jaganjac, J; Glamočlija, U; Mehić, M; Popović, Ž; Šukalo, A; Tanović Avdić, A; Tirić Čampara, M, 2022) |
| "To evaluate efficacy on blood pressure reduction and acceptability of the single pill combination of Perindopril/Indapamide in patients with moderate to severe hypertension." | 9.30 | Evaluation of Clinical Acceptability of Perindopril / Indapamide Single-pill Combination in Moderate to Severe Hypertension. ( Jabre, G; Joseph, S; Kalra, S; Rajarshi, M; Shah, SN; Sosale, A, 2019) |
| "In this prospective open-label study, 92 patients with essential hypertension were randomized to treatment with a TFC of perindopril/indapamide/amlodipine at different doses or a triple free combination therapy (FCT) including ACEI/diuretic/CCB." | 9.30 | Long-term effect of the perindopril/indapamide/amlodipine single-pill combination on left ventricular hypertrophy in outpatient hypertensive subjects. ( Lenti, S; Mazza, A; Rigatelli, G; Rossetti, C; Rubello, D; Schiavon, L; Torin, G; Townsend, DM, 2019) |
| "To examine the antihypertensive efficacy and safety of indapamide sustained-release (SR)/amlodipine compared with enalapril/amlodipine in patients 65 years and older with uncontrolled blood pressure (BP) on monotherapy, a post hoc analysis of the NESTOR trial (Natrilix SR vs Enalapril in Hypertensive Type 2 Diabetics With Microalbuminuria) was conducted." | 9.24 | Blood pressure-lowering efficacy of indapamide SR/amlodipine combination in older patients with hypertension: A post hoc analysis of the NESTOR trial (Natrilix SR vs Enalapril in Hypertensive Type 2 Diabetics With Microalbuminuria). ( Boully, C; Caillard, L; Chaussade, E; Hanon, O; Hernandorena, I, 2017) |
| "The single-pill combination (SPC) of perindopril (PER)/indapamide (IND)/amlodipine (AML) is a valuable and convenient treatment option for patients with hypertension controlled with two-drug SPC of PER/IND + AML given as two separate pills at the same dose level." | 9.22 | Perindopril/Indapamide/Amlodipine in Hypertension: A Profile of Its Use. ( Syed, YY, 2022) |
| "An international double-blind, parallel-group, randomized controlled trial was performed to determine the efficacy and safety of a new first-line strategy in mild to moderate hypertension based on a single-pill combination of perindopril/amlodipine versus a validated stepped-care strategy (initiation with valsartan monotherapy, up-titrating to valsartan/amlodipine after 2 months)." | 9.20 | Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine. ( Amodeo, C; Asmar, R; Chazova, IE; Gamba, MA; Mancia, G; Mourad, JJ; Puig, JG; Taddei, S, 2015) |
| "Hypertensive diabetic patients with microalbuminuria were included in this retrospective, post-hoc analysis of the Natrilix SR Versus Enalapril Study in Hypertensive Type 2 Diabetics With MicrOalbuminuRia (NESTOR) trial if they were uncontrolled on monotherapy (indapamide slow release (SR) 1." | 9.20 | Treatment of Hypertensive Patients With Diabetes and Microalbuminuria With Combination Indapamide SR/Amlodipine: Retrospective Analysis of NESTOR. ( Boully, C; Caillard, L; Chaussade, E; Cochiello, S; Hanon, O; Labourée, F, 2015) |
| " The EFFICIENT study examines the efficacy and acceptability of a single-pill combination of sustained-release (SR) indapamide, a thiazide-like diuretic, and amlodipine, a calcium channel blocker (CCB), in the management of hypertension." | 9.19 | Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study. ( Gujral, VK; Hiremath, J; Jadhav, U; Namjoshi, DJ; Safar, M; Shamanna, P; Siraj, M; Tripathi, KK, 2014) |
| "The objective of this study is to compare the effects of 2 types of diuretics, indapamide and hydrochlorothiazide, added to an angiotensin-converting enzyme inhibitor, on ventricular and arterial functions in patients with hypertension and diabetes." | 9.19 | The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: results of a randomized trial. ( Cinteza, M; Ciobanu, AO; Dragoi Galrinho, R; Dulgheru, R; Florescu, M; Granger, C; Magda, S; Vinereanu, D, 2014) |
| "In patients with arterial hypertension and left ventricular hypertrophy, perindopril + indapamide reduced blood pressure and left ventricular mass index and improved resting and hyperaemic myocardial blood flow." | 9.15 | Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension. ( Camici, PG; D'amati, G; Donato, L; Fommei, E; Ghione, S; Lombardi, M; Mancini, M; Neglia, D; Parker, H; Pisani, P; Varela-Carver, A, 2011) |
| "Patients with cerebrovascular disease and hypertension at baseline (n=4283) were randomly assigned to either active treatment (perindopril in all participants plus indapamide for those with neither an indication for nor a contraindication to a diuretic) or matching placebo(s)." | 9.15 | Effects of blood pressure lowering on major vascular events among patients with isolated diastolic hypertension: the perindopril protection against recurrent stroke study (PROGRESS) trial. ( Anderson, C; Arima, H; Chalmers, J; Hata, J; Macmahon, S; Murakami, Y; Neal, B; Omae, T; Woodward, M, 2011) |
| "The combination of an ACEI and indapamide improved BP control, but attenuated the beneficial effects of ACE inhibition on plasma adiponectin in patients with essential hypertension." | 9.14 | Combination of an ACE inhibitor and indapamide improves blood pressure control, but attenuates the beneficial effects of ACE inhibition on plasma adiponectin in patients with essential hypertension. ( Chen, JW; Huang, SS; Lin, SJ; Wu, TC, 2009) |
| "the Hypertension in the Very Elderly Trial (HYVET) was a double-blind placebo-controlled trial of a thiazide-like diuretic (indapamide 1." | 9.14 | The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Burch, L; de Vernejoul, MC; Duggan, J; Fletcher, A; Gil-Extremera, B; Liu, L; Peters, R; Swift, C, 2010) |
| "The aim of the observational pharmaco-epidemiological study Optimax II was to seek whether the pre-existence of a metabolic syndrome (MS) defined by the NCEP-ATP III criteria impacts blood pressure (BP) control in hypertensive patients receiving a fixed perindopril/indapamide combination therapy." | 9.13 | Blood pressure normalization by fixed perindopril/indapamide combination in hypertensive patients with or without associate metabolic syndrome: results of the OPTIMAX 2 study. ( Guillausseau, PJ; Lameira, D; Mourad, JJ, 2008) |
| "To assess real-life effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in patients with hypertension (HT) and type 2 diabetes mellitus (T2DM), obesity and/or metabolic syndrome (MetS)." | 9.12 | Beneficial Effects of a Perindopril/Indapamide Single-Pill Combination in Hypertensive Patients with Diabetes and/or Obesity or Metabolic Syndrome: A Post Hoc Pooled Analysis of Four Observational Studies. ( Brzozowska-Villatte, R; De Champvallins, M; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021) |
| " Patients with systolic-diastolic or isolated systolic hypertension (n = 1758) received indapamide (1." | 9.12 | Indapamide SR versus candesartan and amlodipine in hypertension: the X-CELLENT Study. ( Asmar, R; Calvo, C; London, G; Schmieder, R, 2006) |
| "To evaluate the efficacy and tolerability of the first line combination perindopril/indapamide in hypertension in daily practice." | 9.12 | Efficacy and tolerability of the perindopril/indapamide combination therapy for hypertension: the PRIMUS study. ( Holzgreve, H; Risler, T; Trenkwalder, P, 2006) |
| "investigate and compare the effect of valsartan and indapamide on inflammatory cytokines in hypertension." | 9.12 | Effects of valsartan and indapamide on plasma cytokines in essential hypertension. ( Sun, ZL; Wang, YJ; Xie, QY; Yang, TL, 2006) |
| "Therapy with the use of a fixed combination of perindopril and indapamide was prescribed to 22 patients with metabolic syndrome and I - II degree hypertension for 16 weeks." | 9.12 | [Effect of a fixed combination of perindopril and indapamide on 24-hour blood pressure profile, morpho-functional parameters of the heart, heart rate variability, functional state of the kidney, and quality of life in patients with arterial hypertension c ( Statsenko, ME; Zemlianskaia, MM, 2007) |
| "The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) showed that blood pressure lowering reduced stroke risk in patients with a history of cerebrovascular events." | 9.11 | Effects of a perindopril-based blood pressure-lowering regimen on the risk of recurrent stroke according to stroke subtype and medical history: the PROGRESS Trial. ( Anderson, C; Bousser, MG; Chalmers, J; Chapman, N; Colman, S; Davis, S; Donnan, G; Huxley, R; MacMahon, S; Neal, B; Warlow, C; Woodward, M, 2004) |
| "To test whether microalbuminuria in patients with type 2 diabetes and hypertension is primarily dependent on the severity of hypertension, and to compare the effectiveness of two antihypertensive drugs with opposite effects on the renin-angiotensin system [the diuretic, indapamide sustained release (SR), and an angiotensin-converting enzyme inhibitor, enalapril] in reducing microalbuminuria." | 9.11 | Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study. ( Amouyel, P; Asmar, R; Fernandez, M; Finizola, B; Gallois, Y; Halabe, A; Hermansen, K; Ionescu-Tirgoviste, C; Jermendy, G; Kokot, F; Marre, M; Mion Júnior, D; Moyseev, V; Ollivier, JP; Opie, L; Puig, JG; Ruiz, M; Saldanha, MH; Scheen, A; Tuomilehto, J; Williams, B, 2004) |
| "A first line management of hypertension based on a low-dose combination of perindopril and indapamide allows the normalization of blood pressure in significantly more patients than a 'sequential monotherapy' strategy involving atenolol, losartan and amlodipine, and a 'stepped-care' strategy involving valsartan and hydrochlorothiazide." | 9.11 | Comparison of different therapeutic strategies in hypertension: a low-dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped-care approach. ( Andréjak, M; Duru, G; Laville, M; Mourad, JJ; Waeber, B; Zannad, F, 2004) |
| "This study was a subsidiary analysis of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS)--a randomized, placebo-controlled trial that established the beneficial effects of blood pressure--lowering in a heterogeneous group of patients with cerebrovascular disease." | 9.11 | Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack. ( Anderson, C; Arima, H; Chalmers, J; Colman, S; Hart, RG; MacMahon, S; Neal, B; Rodgers, A; Woodward, M, 2005) |
| "25 mg) (Noliprel forte) and captopril (50 mg) with hydrochlorothiazide (25 mg) (Capozide) were compared in a randomized study on 40 patients with I-II degree high and very high risk hypertension." | 9.11 | [Comparative efficacy of fixed dose combinations of perindopril with indapamide and captopril with hydrochlorothiazide in patients with high risk hypertension]. ( Brel', UA; Chaliabi, TA; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VV, 2005) |
| "Monotherapy with indapamide is associated with greater BP reduction and control and response rates than monotherapy with low-dose hydrochlorothiazide and may be an appropriate choice of antihypertensive diuretic therapy in black South African patients with mild to moderate hypertension." | 9.10 | Comparison of indapamide and low-dose hydrochlorothiazide monotherapy in black patients with mild to moderate hypertension. ( Candy, GP; Ngcezula, T; Radevski, IV; Sareli, P; Valtchanova, ZP; Wald, AM, 2002) |
| "The aim of the study was to evaluate efficacy and tolerability of two different fixed combinations of an angiotensin-converting enzyme inhibitor and a diuretic: delapril+indapamide (D+I) and captopril+hydrochlorothiazide (C+H) administered for 6 months to patients with mild to moderate essential hypertension." | 9.10 | Evaluation of the efficacy and tolerability of the combination delapril plus indapamide in the treatment of mild to moderate essential hypertension: a randomised, multicentre, controlled study. ( Rizzoni, D; Rosei, EA, 2003) |
| "The effectiveness as well as the metabolic effects of the combination of diuretics [hydrochlorothiazide (HCT) vs indapamide (IND)] and perindopril (P) in 14 patients (7 male, 7 female) aged 37-62 years with mild idiopathic hypertension were studied." | 9.09 | Effectiveness and metabolic effects of perindopril and diuretics combination in primary hypertension. ( Elisaf, MS; Kalaitzidis, R; Katopodis, K; Papagalanis, N; Pappas, H; Siamopoulos, KC; Theodorou, J, 1999) |
| "The primary aim of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) is to determine the effects of a long-term angiotensin converting enzyme (ACE)-inhibitor-based blood-pressure-lowering regimen on the risk of stroke among patients with a history of stroke or transient ischaemic attack (TIA)." | 9.09 | PROGRESS - Perindopril Protection Against Recurrent Stroke Study: characteristics of the study population at baseline. Progress Management Committee. ( , 1999) |
| "To establish the optimal dose of the perindopril/indapamide combination (Per/Ind) in the treatment of mild or moderate hypertension." | 9.09 | Fixed low-dose combination therapy in hypertension--a dose response study of perindopril and indapamide. ( Asmar, R; Leenen, FH; Myers, MG; Safar, M, 2000) |
| "The LIVE study (left ventricular hypertrophy regression, indapamide versus enalapril) was a 1 year, prospective, randomized, double-blind study." | 9.09 | Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study. ( Chastang, C; de Leeuw, PW; Degaute, JP; Dubourg, O; Gosse, P; Guéret, P; Karpov, Y; Motz, W; Palma-Gamiz, JL; Pessina, A; Sheridan, DJ; Zannad, F, 2000) |
| "625 mg (P/I) compared with the angiotensin II antagonist losartan 50 mg (L50) in the treatment of essential hypertension." | 9.09 | Antihypertensive efficacy and tolerability of low-dose perindopril/indapamide combination compared with losartan in the treatment of essential hypertension. ( Chanudet, X; De Champvallins, M, 2001) |
| "To study effects of perindopril, indapamid and their combination on stratification of essential hypertension (EH) risk factors." | 9.09 | [Effects of perindopril and its combination with indapamide on risk stratification in patients with hypertension]. ( Ol'binskaia, LI; Zheleznykh, EA, 2001) |
| "625 mg indapamide in essential hypertension." | 9.09 | Clinical benefit of very-low-dose perindopril-indapamide combination in hypertension. ( Laurent, S, 2001) |
| "To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)." | 9.08 | Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995) |
| "The long-term effects of indapamide or hydrochlorothiazide on blood pressure and renal function were examined in patients with impaired renal function and moderate hypertension." | 9.08 | Comparison between the effects of indapamide and hydrochlorothiazide on creatinine clearance in patients with impaired renal function and hypertension. ( Gadallah, M; Madkour, H; Massry, SG; Plante, GE; Riveline, B, 1995) |
| "25 mg) of indapamide (Lozol, Rhône-Poulenc Rorer Pharmaceuticals, Collegeville, PA) was evaluated in 222 elderly patients (> or = 50 years) with mild to moderate essential hypertension in a multicenter, randomized, double-blind, parallel-group clinical trial." | 9.08 | Efficacious response with lower dose indapamide therapy in the treatment of elderly patients with mild to moderate hypertension. ( Codispoti, J; Curry, C; Ferdinand, K; Jain, AK; Jallad, NS; McNally, C; Schnaper, HW; Stokes, A; Toth, PD; Weidler, D, 1995) |
| "This report describes the effects of indapamide versus transdermal clonidine on left ventricular hypertrophy (LVH) in hypertensive diabetic patients." | 9.08 | Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. ( Berk, LS; Tan, LG; Tan, SA, 1996) |
| "The long-term effects of indapamide or hydrochlorothiazide on blood presssure and renal function were examined in patents with impaired renal function and moderate hypertension." | 9.08 | Indapamide is superior to thiazide in the preservation of renal function in patients with renal insufficiency and systemic hypertension. ( Gadallah, M; Madkour, H; Massry, SG; Plante, GE; Riveline, B, 1996) |
| " The present multicenter open study was designed to test the effects of indapamide, a widely used nonthiazide diuretic, on LVH in patients with essential hypertension." | 9.08 | Regression of left ventricular hypertrophy in patients with essential hypertension. Results of 6 month treatment with indapamide. ( Balazovjech, I; Barrandon, S; Brault, Y; Brown, R; Curry, CL; de Cordoüe, A; Galinier, F; Guez, D; Honos, G; Mariani, M; Olivan, J; Robinson, H; Ruddy, TD; Sami, M; Touzek, F, 1996) |
| "We conclude that the safety and efficacy of perindopril + indapamide, captopril + hydrochlorothiazide and enalapril + hydrochlorothiazide were equivalent after 8 weeks of treatment in patients with mild to moderate hypertension." | 9.08 | An equivalence study of the safety and efficacy of a fixed-dose combination of perindopril with indapamide versus fixed-dose combinations of captopril with hydrochlorothiazide and enalapril with hydrochlorothiazide in the treatment of hypertension. ( Brault, Y; Chastang, C; Di Perri, T; Guez, D; Laurandin, I; Luccioni, R; Redon, J; Sever, PS, 1995) |
| "5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)." | 9.07 | Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993) |
| "Evaluate the clinical efficacy and quality of life of indapamide in patients with mild and moderate arterial systemic hypertension under indapamide." | 9.07 | [Hypertension and well-being: a study with indapamide]. ( Alfaiate, A; Carrageta, MO; Corrêa-Nunes, A; Gouveia-Oliveira, A; Macieira, L; Matias, F; Rodrigues, T, 1994) |
| "The effect of long-term treatment with indapamide in platelet alpha 2-adrenoceptors has been evaluated in 10 patients with essential hypertension, in a double-blind, cross-over study with placebo." | 9.06 | Platelet alpha 2-adrenoceptor modifications induced by long-term treatment with indapamide in essential hypertension. ( Bardelli, M; Carretta, R; Cesanelli, R; Fabris, B; Fischetti, F; Giraldi, T; Greco, PL; Melchior, C; Muiesan, S; Pizzolitto, A, 1988) |
| "5 mg indapamide was compared in patients with essential hypertension, known as responders to diuretic therapy." | 9.06 | Comparative study on the antihypertensive efficacy of torasemide and indapamide in patients with essential hypertension. ( Achhammer, I; Glocke, M; Metz, P; Spannbrucker, N, 1988) |
| "This study, carried out in three centers in the United States, investigated the antihypertensive effect of three dosages of indapamide in 87 patients with mild to moderate hypertension." | 9.05 | Multicenter dose-response study of the effect of indapamide in the treatment of patients with mild to moderate hypertension. ( Bolton, S; Capone, P; Neiss, ES; Reeves, RL; Vukovich, RA, 1983) |
| "A double-blind trial was carried out in 24 patients with mild hypertension to compare the efficacy and tolerability of indapamide with that of a standard thiazide diuretic, hydrochlorothiazide." | 9.05 | Indapamide in the treatment of essential arterial hypertension: results of a controlled study. ( Plante, GE; Robillard, C, 1983) |
| "Fifteen out-patients with moderate hypertension were randomly and sequentially treated with atenolol, indapamide and a combination of the two drugs after a wash-out period of at least 1 week and a 2-week placebo run-in period." | 9.05 | Indapamide and atenolol in the treatment of hypertension: double-blind comparative and combination study. ( De Divitiis, O; Di Somma, S; Fazio, S; Ligouri, V; Petitto, M, 1983) |
| "The effect of chronic treatment with indapamide on blood pressure (BP), baroreceptor sensitivity (BRS) and vascular reactivity (VR) were investigated in 10 patients with essential hypertension." | 9.05 | Effect of indapamide on the baroreceptor reflex in essential hypertension. ( Battilana, G; Bellini, G; Bianchetti, A; Campanacci, L; Carretta, R; Fabris, B; Tonutti, L, 1983) |
| "Twenty-four patients (average age 72 years) took part in a study of the effectiveness and tolerance of indapamide as medication for essential hypertension in elderly subjects." | 9.05 | Indapamide in the treatment of essential arterial hypertension in the elderly. ( Brems, H; Thomas, J; Van Hee, W, 1981) |
| "A total of 1600 patients with essential arterial hypertension was recruited from 10 countries, and treated with indapamide according to a common protocol." | 9.05 | International multicentre study of indapamide in the treatment of essential arterial hypertension. ( Desprat, J; Passeron, J; Pauly, N, 1981) |
| "1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 9.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
| "Indapamide and methyldopa were compared in an open parallel study in patients with mild or moderate hypertension." | 9.05 | Indapamide in ambulant treatment of hypertension: a comparative study with alpha-methyldopa. ( Meine, H, 1981) |
| "A multi-centre open trial involving 150 cardiologists throughout France was undertaken to assess the efficacy and tolerance of indapamide in the treatment of essential hypertension." | 9.05 | The efficacy and tolerance of indapamide in essential hypertension: a multi-centre study in 981 patients. ( Abbou, CB, 1985) |
| "A controlled multicentre trial was organised to compare the effects of 20 mg Nifedipine tablets (N) and 2,5 mg Indapamide tablets (I) during a 4 months' treatment period after a placebo period, in 59 patients with moderate essential hypertension (n = 59)." | 9.05 | [Comparative effects of nifedipine and indapamide in the treatment of arterial hypertension]. ( Aubert, P; Chaignon, M; Guédon, J; Lucsko, M; Rapoud, JP, 1985) |
| " Fifty-three patients with mild essential hypertension (WHO groups I and II) in three medical centers were treated with either muzolimine or indapamide, which served as the reference preparation, in a randomised, double-blind study." | 9.05 | Clinical evaluation of muzolimine and indapamide during treatment for essential hypertension. ( Kirsten, R; Molz, KH; Nelson, K; Tzonev, I, 1985) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 8.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "A systematic literature search is undertaken for supporting the pharmacological proprieties and clinical efficacy of perindopril in the treatment of hypertension." | 8.87 | Perindopril for the treatment of hypertension. ( Ghiadoni, L, 2011) |
| "We searched MEDLINE (1966-April 2003), EMBASE (1980-March 2003), BIOSIS (1999-December 2002), and the Cochrane Library, using the medical subject headings with the search terms perindopril, indapamide, hypertension, randomized controlled trials, randomly, random, randomization, perindopril-indapamide, essential hypertension, and primary hypertension." | 8.82 | A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension. ( An, N; Kang, S; Ren, M; Wu, YF, 2004) |
| "The fixed low-dose combination of the ACE inhibitor perindopril and the non-thiazide diuretic indapamide has been evaluated in the management of patients with mild to moderate hypertension." | 8.81 | Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. ( Cheer, SM; Goa, KL; Matheson, AJ, 2001) |
| "This study evaluated the effectiveness of treatment with an indapamide/amlodipine single-pill combination (SPC) in outpatients with uncontrolled isolated systolic hypertension (ISH) aged over 55 years in real-life clinical practice." | 8.12 | Effectiveness of indapamide/amlodipine single-pill combination in patients with isolated systolic hypertension: post-hoc analysis of the ARBALET study. ( Goreva, LA; Karapetyan, LV; Kobalava, ZD; Kolesnik, EL; Shavarova, EK, 2022) |
| "A total of 198 patients with hypertension in ambulatory care who had been on fixed-dose combination of perindopril arginine, indapamide, and amlodipine for at least 4 weeks were included." | 8.12 | Use of Perindopril Arginine/Indapamide/Amlodipine in the Management of Hypertension in Two Sub-Saharan African Island Countries of Madagascar and Mauritius. ( Ackbarkhan, A; Mbanya, A; Mbanya, JC; Mittoo, MY; Ramamonjisoa, HA; Ramilitiana, B; Ranivoharisoa, EM; Ratsimbazafy, SJN, 2022) |
| "Our objective was to determine the effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in a broad range of patient profiles, including subgroups with varying hypertension severity, age and cardiovascular risk profiles." | 8.02 | Effectiveness of Perindopril/Indapamide Single-Pill Combination in Uncontrolled Patients with Hypertension: A Pooled Analysis of the FORTISSIMO, FORSAGE, ACES and PICASSO Observational Studies. ( Brzozowska-Villatte, R; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021) |
| "to investigate the impact of indapamide / perindopril single-pill combination (I / P SPC) on arterial stiffness parameters, blood pressure (BP) level and BP variability (BPV) in middle-aged patients with stage II grade 1-2 essential arterial hypertension (EAH)." | 7.91 | [Single Pill Indapamide and Perindopril Arginine Combination: Optimal Coupling of Vascular Protection and Hemodynamic Risk Factors Reduction in Patients with Essential Arterial Hypertension]. ( Borisova, EV; Kochetkov, AI; Ostroumova, OD, 2019) |
| "to assess the potential of fixed perindopril/indapamide combination (FPIC) to improve angioprotection in patients with arterial hypertension (AP) with various efficacy of preceding therapy with combination of losartan and hydrochlorothiazide (HCTZ)." | 7.85 | [Optimization of Control of Blood Pressure, Metabolic Disorders and Target Organs Protection With Fixed Perindopril and Indapamide Combination in Treated Patients With Arterial Hypertension]. ( Chumachek, EV; Hripaeva, VJ; Ledyaeva, AA; Nedogoda, SV; Palashkin, RV; Salasyuk, AS; Smirnova, VO; Tsoma, VV, 2017) |
| " FC, two extreme approaches are presented: with difference in effectiveness due to improved adherence to the treatment estimated from published studies on other molecules used in hypertension such as SPCs and FCs - the base-case approach (1); and assuming no difference of effectiveness or adherence between SPC and FC of indapamide and amlodipine - the conservative approach (2)." | 7.81 | Economic evaluation of single-pill combination of indapamide and amlodipine in the treatment of arterial hypertension in the Polish setting. ( Borowiec, Ł; Filipiak, KJ; Holko, P; Kawalec, P; Stawowczyk, E, 2015) |
| " Our study evaluated the efficacy of triple therapy with perindopril, amlodipine, and indapamide sustained release (SR) in patients with uncontrolled hypertension on previous antihypertensive therapy." | 7.80 | Triple combination therapy in hypertension: the antihypertensive efficacy of treatment with perindopril, amlodipine, and indapamide SR. ( Páll, D; Szabó, Z; Szántó, I, 2014) |
| "Triplixam is a fixed dose combination of three well known antihypertensive agents, with complementary activities, to control blood pressure in patients with arterial hypertension: perindopril, an angiotensin converting enzyme inhibitor, indapamide, a diuretic whith thiazide-like effects but also specific properties, and amlodipine, a long-acting calcium antagonist of the dihydropyridine family." | 7.80 | [Fixed dose combination perindopril-indapamide-amlodipine (Triplixam) for the treatment of arterial hypertension]. ( Krzesinski, JM; Lancellotti, P; Scheen, AJ, 2014) |
| "The aim of the study was to investigate the dynamics of arterial stiffness and endothelial function parameters under the influence of perindopril arginine and indapamide fixed combination in arterial hypertension (AH) patients." | 7.78 | [Vascular effects of perindopril arginine and indapamide fixed combination in patients with arterial hypertension]. ( Golubeva, LV; Logovikova, SI; Protasov, KV; Reshina, IV; Sinkevich, DA; Zhizhko, NV, 2012) |
| "The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis." | 7.77 | The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011) |
| "To study ways of realization of pleiotropic effects of treatment with low-dose combination of perindopril arginine with indapamide in hypertensive patients with metabolic syndrome (MS)." | 7.77 | [Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome]. ( , 2011) |
| "Indapamide(1 mg) was given daily for 3 months and was then given every other day for 3 months to patients whose hypertension was poorly controlled with angiotensin II receptor blocker (ARB)-based treatment." | 7.76 | Effects of additional administration of low-dose indapamide on patients with hypertension treated with angiotensin II receptor blocker. ( Kusunose, K; Mishiro, Y; Sata, M; Yamada, H, 2010) |
| "The effects of indapamide, a thiazide-like diuretic, and captopril, an angiotensin-converting enzyme inhibitor, on spontaneous hypertension and the development of left ventricular hypertrophy (LVH), nitric oxide generation and oxidant status were investigated." | 7.75 | Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension. ( Jendekova, L; Paulis, L; Pechanova, O; Simko, F; Sladkova, M; Vranková, S, 2009) |
| "To compare efficacy of use of the blocker of aldosteron receptors spironolactone and diuretic indapamide in low-renin arterial hypertension (AH), their action on blood pressure, serum concentrations of sodium, potassium, creatinine, plasmic renin activity (PRA), plasmic aldosteron concentration (PAC)." | 7.73 | [Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. ( Bagdonas, G; Kazanavichus, G; Naudzhunas, A; Yankauskene, L, 2006) |
| "Patients (n=50) with essential hypertension were given either indapamide-retard (1." | 7.73 | [Comparative assessment of hypotensive, metabolic, and endothelial effects of indapamide-retard and hydrochlorothiazide in patients with essential hypertension]. ( Golevtsova, ZSh; Nazarov, AG; Potapov, VV; Pritykina, TV; Protskiĭ, IA; Semenkin, AA; Zhivilova, LA, 2006) |
| "To assess changes of blood pressure (BP) and processes of cardiovascular remodeling during treatment of previously untreated patients with hypertension with fixed low dose combination of perindopril and indapamide." | 7.72 | [Effect of fixed low dose combination of perindopril and indapamide on processes of cardiovascular remodeling in previously untreated patients with hypertension]. ( Anisimova, LP; Ivanenko, VV; Legkiĭ, AV; Lopatin, IuM; Riazantseva, NV; Semenova, NV, 2004) |
| "To study therapy with indapamide impairing carbohydrate metabolism in essential hypertension patients and achieve earlier prevention, diagnoses and treatment of diabetes induced by indapamide." | 7.72 | Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports). ( Jian-Li, Q; Jian-Liang, Z; Jiang, C; Rong-Liang, X; Xing, Z; Yong-Wen, Q, 2004) |
| "Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp)." | 7.71 | Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment. ( Bacchelli, B; Biagini, G; Contri, MB; Miselli, M; Pedrazzi, G; Taparelli, F, 2002) |
| " In this study, 21 patients with noninsulin-dependent diabetes and hypertension (11 with normoalbuminuria and 10 with microalbuminuria), who were comparable for age, duration of diabetes and hypertension, were treated with indapamide, 2." | 7.68 | Efficacy of antihypertensive treatment with indapamide in patients with noninsulin-dependent diabetes and persistent microalbuminuria. ( Frontoni, S; Gambardella, S; Gargiulo, P; Grazia Felici, M; Menzinger, G; Morano, S; Spallone, V, 1990) |
| "Renal plasma flow (RPF), glomerular filtration rate (GFR), arginine vasopressin in plasma (AVP), free water clearance (CH2O) and blood pressure (BP) were determined in 11 patients with essential hypertension at the end of 3 consecutive periods of observation each of 6 of weeks duration; indapamide 2." | 7.67 | Effect of indapamide on renal plasma flow, glomerular filtration rate and arginine vasopressin in plasma in essential hypertension. ( Danielsen, H; Pedersen, EB; Spencer, ES, 1984) |
| "The effects of indapamide on diabetic patients with micro-albuminuria were evaluated in a multicentre study to assess the advantages of this compound in long-term renal protection." | 7.67 | Hypertension and micro-albuminuria in diabetic patients taking indapamide. ( Blümner, E; Janka, HU; Mehnert, H; van Michel, A; Weitz, T, 1989) |
| "The efficacy of captopril alone or in combination with indapamide was evaluated in 17 patients with severe hypertension (diastolic greater than 120 mmHg) previously treated with triple antihypertensive therapy, i." | 7.67 | Antihypertensive effect of indapamide given in conjunction with captopril in severe hypertension. ( Dimkovic, S; Kocijancic, M, 1986) |
| "Fourteen patients with untreated mild to moderate essential hypertension had, on average, an abnormally high cardiovascular reactivity to exogenous noradrenaline and angiotensin II, while plasma noradrenaline, renin activity, exchangeable body sodium, and blood volume were normal." | 7.66 | Correction of altered noradrenaline reactivity in essential hypertension by indapamide. ( Beretta-Piccoli, C; Glück, Z; Grimm, M; Keusch, G; Meier, A; Weidmann, P; Ziegler, W, 1983) |
| "The effects of acute and chronic administration of indapamide on systemic and renal haemodynamics were studied in 10 patients with arterial essential hypertension." | 7.66 | Effects of the acute and chronic administration of indapamide on systemic and renal haemodynamics in essential hypertension. ( Anguas, MC; Degandarias, L; Meza, U; Nuñez-Poissot, E; Villarreal, H, 1983) |
| "The antihypertensive effect and a non-invasive cardiovascular assessment of indapamide in patients with idiopathic hypertension have been investigated in an uncontrolled study." | 7.66 | Non-invasive cardiovascular assessment of indapamide in patients with essential hypertension. ( Dunn, FG; Hillis, WS; Lorimer, AR; Rae, AP; Tweddel, A, 1981) |
| "The onset of DOCA-salt hypertension in male Sprague-Dawley rats was prevented during 11 weeks of oral treatment with indapamide (0." | 7.66 | The effects of long term oral treatment with indapamide on the development of DOCA-salt hypertension in rats: vascular reactivity studies. ( Hicks, PE, 1979) |
| "Hypertension has a major associated risk for organ damage and mortality, which is further heightened in patients with prior cardiovascular events, comorbid diabetes mellitus, microalbuminuria and renal impairment." | 6.82 | The advantages of combination therapy on hypertension: development of immediate release perindopril-indapamide tablet and assessment of bioequivalence studies. ( İnce, I; Karasulu, E; Ölçer, A; Ölçer, M, 2016) |
| " Perindopril/indapamide dosage could be increased, from 5/1." | 6.79 | Efficacy of single-pill perindopril/indapamide in patients with hypertension and type 2 diabetes. ( Gorbat, TV; Netchessova, TA; Shepelkevich, AP, 2014) |
| "Perindopril/indapamide treatment reduced 24-hour and daytime systolic BP (SBP) and pulse pressure (PP) significantly more than enalapril treatment (p < 0." | 6.73 | Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy. ( Asmar, R; De Leeuws, PW; Garcia-Puig, J; Gosse, P; Karpov, YA; Magometschniggs, D; Matos, L; Schmieder, R, 2007) |
| " Once daily dosing of the preparation provided high level of compliance of patients with treatment." | 6.72 | [Effect of twelve-month combined therapy with perindopril and indapamide on the level of blood pressure and left ventricular hypertrophy in patients with hypertensive disease]. ( Alekhin, MN; Chumakova, OS; Larina, VN; Sidorenko, BA; Timofeeva, LA; Ugriumov, MO, 2006) |
| "Perindopril/indapamide treatment led already after 4 weeks to a significant blood (BP) reduction with most prominent BP differences at the end of the study (sitting BP 130 +/- 10/84 +/- 6 mm Hg vs." | 6.71 | [Evaluation of the antihypertensive efficacy and tolerability of fixed very low-dose perindopril/indapamid combination in patients with mild to moderate hypertension. Results of a Czech and Slovak multicentric study]. ( Fedelesová, V; Widimský, J, 2004) |
| "In the overall population, there was a significant dose-response relationship (P < 0." | 6.70 | Gender influence on the dose-ranging of a low-dose perindopril-indapamide combination in hypertension: effect on systolic and pulse pressure. ( Asmar, R; Leenen, F; Myers, MG; Safar, ME, 2002) |
| "The PICXEL study is designed to evaluate the effects of long-term administration of very low-dose combination perindopril 2 mg/indapamide 0." | 6.70 | Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design. ( Amouyel, P; Asmar, R; Dahlöf, B; De Leeuw, PW; De Simone, G; Degaute, JP; Dubourg, O; García Puig, J; Gosse, P; Guéret, P; Karpov, Y; Le Heuzey, JY; Magometschnigg, D; Matos, L; Nieminen, M; Schmieder, R, 2002) |
| " Adverse event rates (including hypokalemia) were similarly low in both groups." | 6.69 | Efficacy and safety of an oral fixed low-dose perindopril 2 MG/indapamide 0.625 MG combination: a randomized, double-blind, placebo-controlled study in elderly patients with mild to moderate hypertension. ( Castaigne, A; Chalmers, J; Chastang, C; Feldmann, L; Guez, D; Morgan, T, 1999) |
| "Treatment with indapamide 1." | 6.68 | Conversion from 2.5 mg to 1.25 mg indapamide in patients with mild to moderate hypertension. ( Boyd, G; Chrysant, S; Codispoti, J; Dawson, J; Gardner, T; Hill, G; Lee, W; Levine, B; Stokes, A; Vergis, J, 1995) |
| "Indapamide is a diuretic and vasodilator that does not raise blood glucose or lipid levels." | 6.68 | [Indapamide--a substitute diuretic for hypertensives with hyperglycemia and/or dyslipidemia]. ( Grossman, E; Katz, A; Nussinovitch, N; Rachima-Moaz, C; Rosenthal, T; Sharabi, Y, 1996) |
| "Indapamide 1." | 6.68 | Evaluation of indapamide 1.25 mg once daily in elderly patients with mild to moderate hypertension. ( Blumenthal, J; Codispoti, J; Dawson, JE; Dyckman, E; Fiddes, R; Harris, S; Lasseter, KC; Levine, BS; Montoro, R; Niederman, AL; Ratner, PH; Rosenblatt, S; St John Hammond, PG; Toth, PD; Vergis, J, 1997) |
| "Indapamide is an antihypertensive drug suitable for treatment of mild hypertension in diabetics as monotherapy." | 6.67 | [Indapamide in the treatment of hypertension in diabetes]. ( Klabusay, L; Olsovský, J; Podrouzková, B, 1992) |
| "Indapamide is a new, nonthiazide diuretic and vasodilator." | 6.67 | Regression of left ventricular hypertrophy in hypertension with indapamide. ( Haichin, R; Sami, M, 1991) |
| "Since hypertension is an important risk factor of cardiovascular morbidity and mortality that can be at least in part decreased by pharmacologic reduction in elevated blood pressure, it is necessary that an antihypertensive agent be effective, but at the same time well tolerated and, according to some recent hypotheses, have no deleterious effect on serum electrolyte levels, as well as lipoprotein and glucose tolerance." | 6.66 | Tolerability and well-being with indapamide in the treatment of mild-moderate hypertension. An Italian multicenter study. ( Leonetti, G; Rappelli, A; Salvetti, A; Scapellato, L, 1988) |
| "Indapamide was prescribed to replace hydrochlorothiazide, the other antihypertensive drugs being continued in those patients receiving combination therapy." | 6.65 | The treatment of hypertension with indapamide alone or in combination with other drugs. ( L'Homme, C; Lemieux, G, 1983) |
| "Indapamide is a useful antihypertensive agent with good patient tolerance in mild or moderate hypertension and may offer advantages over traditional diuretics in view of its possible vasodilator and calcium-antagonist properties, once-a-day dosage, and good therapeutic effect with prolonged usage." | 6.65 | Clinical efficacy and safety of indapamide in essential hypertension. ( Morledge, JH, 1983) |
| " It is concluded that indapamide and pindolol at the dosage levels used are drugs of comparable antihypertensive activity." | 6.65 | Indapamide versus beta-blocker therapy: a double-blind, crossover study in essential hypertension. ( Jurisic, M; Rumboldt, M; Rumboldt, Z, 1984) |
| "Hypertension is an important risk factor for cardiovascular complications and the need to treat this condition has been well established." | 6.47 | Combination perindopril/indapamide for the treatment of hypertension: a review. ( de Leeuw, PW, 2011) |
| "Indapamide SR was also more effective than enalapril in reducing left ventricular hypertrophy (LVH), and similar reductions in renal end-organ damage, assessed by microalbuminuria, were seen with indapamide SR- and enalapril-based antihypertensive strategies." | 6.43 | Indapamide sustained release: a review of its use in the treatment of hypertension. ( Robinson, DM; Wellington, K, 2006) |
| " The fixed dosage of a once-daily tablet, ensures optimal ease of use and enhances patient compliance." | 6.43 | Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection. ( Gosse, P, 2006) |
| "Indapamide SR 1." | 6.41 | Metabolic profile of indapamide sustained-release in patients with hypertension: data from three randomised double-blind studies. ( Weidmann, P, 2001) |
| "Indapamide is a thiazide-related diuretic drug with antihypertensive properties." | 6.40 | Pharmacological properties of indapamide. Rationale for use in hypertension. ( Bataillard, A; Sassard, J; Schiavi, P, 1999) |
| "Indapamide SR 1." | 6.40 | Clinical implications of indapamide sustained release 1.5 mg in hypertension. ( Donnelly, R, 1999) |
| "Thiazide diuretics in high dosage adversely affect the lipid profile." | 6.39 | A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides. ( Ames, RP, 1996) |
| "Left ventricular hypertrophy is a major risk factor for cardiovascular morbidity and mortality." | 6.39 | Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis. ( Carey, PA; de Cordoue, A; Guez, D; Sheridan, DJ, 1996) |
| "The objective of this non-interventional post-marketing clinical trial was to analyze the antihypertensive effect and safety of a fixed combination of perindopril and indapamide in the treatment of unregulated essential hypertension." | 5.51 | The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study. ( Boloban, A; Džananović Jaganjac, J; Glamočlija, U; Mehić, M; Popović, Ž; Šukalo, A; Tanović Avdić, A; Tirić Čampara, M, 2022) |
| "Aggregate data from four published RCTs conducted versus matching placebo were pooled: PATS, a 2-year study (indapamide), and PROGRESS, a 4-year study (indapamide and perindopril), both in patients with a history of stroke or transient ischemic attack; ADVANCE, a 4-year study in patients with type 2 diabetes and cardiovascular risk factor (single-pill combination perindopril/indapamide) and HYVET, a 2-year study in very elderly hypertensive individuals (indapamide and an option of perindopril)." | 5.41 | Benefit of treatment based on indapamide mostly combined with perindopril on mortality and cardiovascular outcomes: a pooled analysis of four trials. ( Brzozowska-Villatte, R; Chalmers, J; De Champvallins, M; Mancia, G; Mourad, JJ, 2023) |
| "825), high-dose CCBs combined with ARBs controlled hypertension without elevation of serum uric acid." | 5.34 | Assessment of suitable antihypertensive therapies: Combination with high-dose amlodipine/irbesartan vs triple combination with amlodipine/irbesartan/indapamide (ASAHI-AI study). ( Hasebe, N; Koyama, S; Maruyama, J; Morimoto, H; Nakagawa, N; Nakamura, Y; Ogawa, Y; Ohta, T; Saijo, Y; Sato, N; Takeuchi, T; Uekita, K, 2020) |
| "This study showed the clinical efficacy, safety and acceptability of the perindopril/indapamide/amlodipine SPC in patients with grade 2/3 hypertension inadequately controlled with two-drug therapy." | 5.34 | Blood-pressure Lowering Efficacy and Safety of Perindopril / Indapamide / Amlodipine Single-pill Combination in Hypertensive Patients: Phase III Trial in India. ( Chaudhary, G; Joseph, S; Konda Reddy, KM; Murthy, LS; Nikam, P; Rajarshi, M; Sawhney, JP; Shah, S; Thacker, H, 2020) |
| "In hypertensive patients with Type 2 diabetes, a greater reduction of urinary albumin excretion can be obtained with the perindopril/indapamide association compared with an angiotensin-converting enzyme inhibitor administered as monotherapy." | 5.33 | What can be learned from the experience with the fixed low-dose combination of perindopril/indapamide in the treatment of hypertension? ( Waeber, B, 2005) |
| "Indapamide is a well known blocker of the slow component of the delayed rectifier current leading to prolongation of cardiac repolarization." | 5.33 | QT interval prolongation and torsade de pointes associated with indapamide. ( Alexanian, IP; Efremidis, M; Kardaras, F; Kounas, SP; Letsas, KP; Pappas, LK; Sideris, A, 2006) |
| "Indapamide was immediately stopped, but the QT remained prolonged 2 days later, although the potassium level was normalized." | 5.31 | Indapamide induced syncope in a patient with long QT syndrome. ( Guo, GB; Wang, CP, 2002) |
| "To evaluate efficacy on blood pressure reduction and acceptability of the single pill combination of Perindopril/Indapamide in patients with moderate to severe hypertension." | 5.30 | Evaluation of Clinical Acceptability of Perindopril / Indapamide Single-pill Combination in Moderate to Severe Hypertension. ( Jabre, G; Joseph, S; Kalra, S; Rajarshi, M; Shah, SN; Sosale, A, 2019) |
| "In this prospective open-label study, 92 patients with essential hypertension were randomized to treatment with a TFC of perindopril/indapamide/amlodipine at different doses or a triple free combination therapy (FCT) including ACEI/diuretic/CCB." | 5.30 | Long-term effect of the perindopril/indapamide/amlodipine single-pill combination on left ventricular hypertrophy in outpatient hypertensive subjects. ( Lenti, S; Mazza, A; Rigatelli, G; Rossetti, C; Rubello, D; Schiavon, L; Torin, G; Townsend, DM, 2019) |
| "Indapamide is an orally active sulphonamide diuretic agent." | 5.27 | Indapamide. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. ( Avery, GS; Brogden, RN; Chaffman, M; Heel, RC; Speight, TM, 1984) |
| " There is growing experimental and clinical evidence that indapamide, an antihypertensive agent with only limited diuretic activity at low dosage (2." | 5.27 | The place of indapamide in the treatment of arterial hypertension. ( Thénot, A, 1983) |
| "Indapamide was well absorbed in every patient (mean plasma level at the steady state was 111 +/- 41 ng/ml) and its antihypertensive action was more pronounced in hypertensive than in normotensive patients." | 5.27 | Acute effect of indapamide on urine calcium excretion in nephrolithiasis and human essential hypertension. ( Amato, F; Barbarese, F; Borghi, L; Elia, G; Melloni, E; Novarini, A; Trapassi, MR, 1988) |
| "The aim of the study is to compare the effects of hydrochlorothiazide and indapamide on the kidney in patients with hypertension inadequately controlled with losartan." | 5.24 | Comparison between the effects of hydrochlorothiazide and indapamide on the kidney in hypertensive patients inadequately controlled with losartan. ( Chen, X; Li, J; Liu, K; Meng, Q; Shi, D; Shi, R; Wang, S; Zhang, X; Zhou, X, 2017) |
| "To examine the antihypertensive efficacy and safety of indapamide sustained-release (SR)/amlodipine compared with enalapril/amlodipine in patients 65 years and older with uncontrolled blood pressure (BP) on monotherapy, a post hoc analysis of the NESTOR trial (Natrilix SR vs Enalapril in Hypertensive Type 2 Diabetics With Microalbuminuria) was conducted." | 5.24 | Blood pressure-lowering efficacy of indapamide SR/amlodipine combination in older patients with hypertension: A post hoc analysis of the NESTOR trial (Natrilix SR vs Enalapril in Hypertensive Type 2 Diabetics With Microalbuminuria). ( Boully, C; Caillard, L; Chaussade, E; Hanon, O; Hernandorena, I, 2017) |
| "The main Hypertension in the Very Elderly Trial (HYVET) demonstrated a very marked reduction in cardiovascular events by treating hypertensive participants 80 years or older with a low dose, sustained release prescription of indapamide (indapamide SR, 1." | 5.24 | Antihypertensive treatment decreases arterial stiffness at night but not during the day. Results from the Hypertension in the Very Elderly Trial. ( Anderson, C; Antikainen, R; Beckett, N; Bulpitt, CJ; Cheek, E; Peters, R; Rajkumar, C; Staessen, JA; Webb, R, 2017) |
| "0% male) with uncontrolled essential hypertension (office systolic BP ≥ 140 or diastolic BP ≥ 90 mmHg) previously treated with a renin-angiotensin-aldosterone system (RAAS) inhibitor plus hydrochlorothiazide were switched to once-daily FDTC therapy with perindopril/indapamide/amlodipine (5-10/1." | 5.24 | Fixed-Dose Triple Combination of Antihypertensive Drugs Improves Blood Pressure Control: From Clinical Trials to Clinical Practice. ( Dell'Avvocata, F; Lenti, S; Mazza, A; Ramazzina, E; Rigatelli, G; Sacco, AP; Schiavon, L, 2017) |
| "The single-pill combination (SPC) of perindopril (PER)/indapamide (IND)/amlodipine (AML) is a valuable and convenient treatment option for patients with hypertension controlled with two-drug SPC of PER/IND + AML given as two separate pills at the same dose level." | 5.22 | Perindopril/Indapamide/Amlodipine in Hypertension: A Profile of Its Use. ( Syed, YY, 2022) |
| "To evaluate the efficacy of perindopril/indapamide/amlodipine single-pill combination in patients with uncontrolled hypertension." | 5.22 | Efficacy of Single-Pill, Triple Antihypertensive Therapy in Patients with Uncontrolled Hypertension: A Systematic Review and Meta-analysis. ( Abdelsattar, AT; Cherfaoui, O; Elmoursi, A; Farhat, AM; Habboush, S; Masoud, AT; Sofy, AA, 2022) |
| "An international double-blind, parallel-group, randomized controlled trial was performed to determine the efficacy and safety of a new first-line strategy in mild to moderate hypertension based on a single-pill combination of perindopril/amlodipine versus a validated stepped-care strategy (initiation with valsartan monotherapy, up-titrating to valsartan/amlodipine after 2 months)." | 5.20 | Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine. ( Amodeo, C; Asmar, R; Chazova, IE; Gamba, MA; Mancia, G; Mourad, JJ; Puig, JG; Taddei, S, 2015) |
| "Hypertensive diabetic patients with microalbuminuria were included in this retrospective, post-hoc analysis of the Natrilix SR Versus Enalapril Study in Hypertensive Type 2 Diabetics With MicrOalbuminuRia (NESTOR) trial if they were uncontrolled on monotherapy (indapamide slow release (SR) 1." | 5.20 | Treatment of Hypertensive Patients With Diabetes and Microalbuminuria With Combination Indapamide SR/Amlodipine: Retrospective Analysis of NESTOR. ( Boully, C; Caillard, L; Chaussade, E; Cochiello, S; Hanon, O; Labourée, F, 2015) |
| "To evaluate the impact of a 12-week combined antihypertensive therapy with enalapril + indapamide on endothelial dysfunction in patients with arterial hypertension (AH) and diabetes mellitus (DM) type 2." | 5.20 | [Possibilities of Correction of Endothelial Dysfunction at the Background of Combined Antihypertensive Therapy in Patients With Arterial Hypertension and Type 2 Diabetes]. ( Derevianchenko, MV; Statsenko, ME, 2015) |
| "Eighty-eight patients with hypertension (stage 1 or 2) were recruited and advised to receive perindopril (4mg), hydrochlorothiazide (25mg), or indapamide (1." | 5.20 | Antihypertensive therapy increases natural immunity response in hypertensive patients. ( Bianco, HT; Boschcov, P; Brandão, SA; Figueiredo-Neto, AM; Fonseca, FA; Fonseca, HA; Gidlund, M; Izar, MC; Juliano, L; Lins, LC; Monteiro, AM; Povoa, RM, 2015) |
| " The EFFICIENT study examines the efficacy and acceptability of a single-pill combination of sustained-release (SR) indapamide, a thiazide-like diuretic, and amlodipine, a calcium channel blocker (CCB), in the management of hypertension." | 5.19 | Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study. ( Gujral, VK; Hiremath, J; Jadhav, U; Namjoshi, DJ; Safar, M; Shamanna, P; Siraj, M; Tripathi, KK, 2014) |
| "The objective of this study is to compare the effects of 2 types of diuretics, indapamide and hydrochlorothiazide, added to an angiotensin-converting enzyme inhibitor, on ventricular and arterial functions in patients with hypertension and diabetes." | 5.19 | The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: results of a randomized trial. ( Cinteza, M; Ciobanu, AO; Dragoi Galrinho, R; Dulgheru, R; Florescu, M; Granger, C; Magda, S; Vinereanu, D, 2014) |
| "Our aim was to compare changes of vascular and metabolic parameters in patients with essential hypertension on treatment with combination of perindopril with either indapamide retard or hydrochlorothiazide." | 5.19 | [Direct comparison of endothelial and metabolic effects of perindopril combination with indapamide retard or hydrochlorothiazide]. ( Chindareva, OI; Nechaeva, GI; Pritykina, TV; Semenkin, AA; Stroeva, TV; Zhenatov, AB; Zhivilova, LA, 2014) |
| "We analyzed 145 out-patients with essential hypertension in primary prevention enrolled in the Natrilix SR Versus Candesartan and Amlodipine in the Reduction of Systolic Blood Pressure in Hypertensive Patients (X-CELLENT) study, a multicenter, randomized, double-blinded, placebo-controlled trial." | 5.17 | Effects of antihypertensive drugs on central blood pressure in humans: a preliminary observation. ( Agnoletti, D; Blacher, J; Borghi, C; Safar, ME; Zhang, Y, 2013) |
| "the Hypertension in the Very Elderly Trial (HYVET) was a randomised placebo-controlled trial of indapamide slow release 1." | 5.17 | Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial. ( Beckett, N; Bulpitt, C; Burch, L; Fagard, R; Fletcher, A; Li, M; Narkiewicz, K; Nitsch, D; Peters, R; Poulter, R; Wang, N, 2013) |
| "To report blood pressure control in the Hypertension in the Very Elderly Trial, a placebo-controlled trial of hypertensive (systolic blood pressure (SBP) 160-199 mm Hg, diastolic blood pressure (DBP) <110 mm Hg) participants over the age of 80 years, given treatment in three steps: indapamide slow release 1." | 5.16 | Blood pressure control in the Hypertension in the Very Elderly Trial (HYVET). ( Banya, W; Beckett, NS; Bulpitt, CJ; Burch, LA; Fagard, R; Fletcher, AE; Gergova, V; Leonetti, G; Peters, R, 2012) |
| "In patients with arterial hypertension and left ventricular hypertrophy, perindopril + indapamide reduced blood pressure and left ventricular mass index and improved resting and hyperaemic myocardial blood flow." | 5.15 | Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension. ( Camici, PG; D'amati, G; Donato, L; Fommei, E; Ghione, S; Lombardi, M; Mancini, M; Neglia, D; Parker, H; Pisani, P; Varela-Carver, A, 2011) |
| " After a 4-week placebo period, 94 and 107 patients with uncomplicated hypertension were randomly assigned to treatment with atenolol (AT) at dosage of 50 mg per day or perindopril/indapamide (PER/IND) at dosage of 2/0." | 5.15 | Responses of the ambulatory arterial stiffness index and other measures of arterial function to antihypertensive drugs. ( Dolan, E; Jin, Y; Li, Y; O'Brien, E; Protogerou, A; Richart, T; Safar, ME; Staessen, JA; Thijs, L; Wang, JG, 2011) |
| "Patients with cerebrovascular disease and hypertension at baseline (n=4283) were randomly assigned to either active treatment (perindopril in all participants plus indapamide for those with neither an indication for nor a contraindication to a diuretic) or matching placebo(s)." | 5.15 | Effects of blood pressure lowering on major vascular events among patients with isolated diastolic hypertension: the perindopril protection against recurrent stroke study (PROGRESS) trial. ( Anderson, C; Arima, H; Chalmers, J; Hata, J; Macmahon, S; Murakami, Y; Neal, B; Omae, T; Woodward, M, 2011) |
| "The REASON (Preterax in Regression of Arterial Stiffness in a Controlled Double-Blind) study is a randomized, double-blind trial comparing atenolol versus perindopril/indapamide; 375 patients with hypertension, with BP and PWV measurements at baseline and after 12 months of treatment, were divided into 3 tertiles according to baseline PWV and included in a post-hoc analysis." | 5.14 | Blood pressure response under chronic antihypertensive drug therapy: the role of aortic stiffness in the REASON (Preterax in Regression of Arterial Stiffness in a Controlled Double-Blind) study. ( Achimastos, A; Blacher, J; Protogerou, A; Safar, ME; Stergiou, GS, 2009) |
| "The Hypertension in the Very Elderly Trial (HYVET) was a double blind placebo-controlled trial of antihypertensive treatment (indapamide SR 1." | 5.14 | Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis. ( Beckett, N; Bulpitt, C; Clarke, R; Fletcher, A; Forette, F; Peters, R; Poulter, R; Ritchie, C; Tuomilehto, J; Waldman, A; Walton, I, 2009) |
| "To investigate antihypertensive efficacy, effects on endothelial, diastolic function of the left ventricle and metabolism of combination of ACE inhibitor quinapril (accupro) with diuretic indapamide SR in patients with hypertension of the second-third degree and type 2 diabetes mellitus (DM) and free of DM." | 5.14 | [Combined antihypertensive treatment of patients with hypertension and type 2 diabetes mellitus]. ( Bondareva, IN; Nesterov, IuI; Poltavtseva, OV; Tepliakov, AT, 2009) |
| "1709 patients with history of stroke or transient ischaemic attack randomised to fixed doses of perindopril and indapamide." | 5.14 | Long term monitoring in patients receiving treatment to lower blood pressure: analysis of data from placebo controlled randomised controlled trial. ( Hayen, A; Irwig, L; Keenan, K; Neal, BC, 2009) |
| "The aim of this work was to investigate influence of indapamide and perindopril on blood pressure and metabolism at patients with type 2 diabetes and new diagnosed arterial hypertension." | 5.14 | [Hypotensive and metabolic effect of indapamide and perindopril in patients with type 2 diabetes and arterial hypertensia]. ( Askerov, MM, 2009) |
| " The objective of the ARGUS-2 study was to demonstrate that a rational use of a thiazide-like diuretic, indapamide sustained release (SR), alone or in combination, improves BP control in patients with arterial hypertension difficult to control due to isolated systolic hypertension (ISH), diabetes mellitus (DM), chronic nephropathy, or metabolic syndrome." | 5.14 | Treating hypertension by rational use of diuretics: results of the Russian ARGUS-2 Study. ( Kobalava, ZD; Kotovskaya, YV; Moiseev, VS; Villevalde, SV, 2009) |
| "The combination of an ACEI and indapamide improved BP control, but attenuated the beneficial effects of ACE inhibition on plasma adiponectin in patients with essential hypertension." | 5.14 | Combination of an ACE inhibitor and indapamide improves blood pressure control, but attenuates the beneficial effects of ACE inhibition on plasma adiponectin in patients with essential hypertension. ( Chen, JW; Huang, SS; Lin, SJ; Wu, TC, 2009) |
| "The aim of the study was to assess effect of 12-week long combined therapy with quinapril (accupro), an ACE inhibitor, and diuretic indapamide SR on arterial pressure (AP), carbohydrate and lipid metabolism, and safety of the treatment in patients having arterial hypertension (AH) with and without DM2." | 5.14 | [Combined antihypertensive therapy in patients with arterial hypertension and type 2 diabetes]. ( Bondareva, IN; Nesterov, IuI; Poltavtseva, OV; Tepliakov, AT, 2009) |
| "the Hypertension in the Very Elderly Trial (HYVET) was a double-blind placebo-controlled trial of a thiazide-like diuretic (indapamide 1." | 5.14 | The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Burch, L; de Vernejoul, MC; Duggan, J; Fletcher, A; Gil-Extremera, B; Liu, L; Peters, R; Swift, C, 2010) |
| "This is a secondary analysis of the Hypertension in the Very Elderly Trial (HYVET), a double blind, placebo controlled trial of indapamide, with or without perindopril, in people aged 80+ years at enrollment." | 5.14 | Modelling cognitive decline in the Hypertension in the Very Elderly Trial [HYVET] and proposed risk tables for population use. ( Beardmore, R; Beckett, N; Bulpitt, C; Mitnitski, A; Mt-Isa, S; Peña-Miller, R; Peters, R; Rockwood, K, 2010) |
| " We conducted a secondary analysis of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS), a large randomized trial of blood pressure lowering to reduce the risk of recurrent stroke." | 5.14 | Monitoring adherence to medication by measuring change in blood pressure. ( Bell, K; Glasziou, P; Hayen, A; Irwig, L; Neal, B, 2010) |
| "The aim of the observational pharmaco-epidemiological study Optimax II was to seek whether the pre-existence of a metabolic syndrome (MS) defined by the NCEP-ATP III criteria impacts blood pressure (BP) control in hypertensive patients receiving a fixed perindopril/indapamide combination therapy." | 5.13 | Blood pressure normalization by fixed perindopril/indapamide combination in hypertensive patients with or without associate metabolic syndrome: results of the OPTIMAX 2 study. ( Guillausseau, PJ; Lameira, D; Mourad, JJ, 2008) |
| "To assess real-life effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in patients with hypertension (HT) and type 2 diabetes mellitus (T2DM), obesity and/or metabolic syndrome (MetS)." | 5.12 | Beneficial Effects of a Perindopril/Indapamide Single-Pill Combination in Hypertensive Patients with Diabetes and/or Obesity or Metabolic Syndrome: A Post Hoc Pooled Analysis of Four Observational Studies. ( Brzozowska-Villatte, R; De Champvallins, M; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021) |
| " Patients with systolic-diastolic or isolated systolic hypertension (n = 1758) received indapamide (1." | 5.12 | Indapamide SR versus candesartan and amlodipine in hypertension: the X-CELLENT Study. ( Asmar, R; Calvo, C; London, G; Schmieder, R, 2006) |
| "To evaluate the efficacy and tolerability of the first line combination perindopril/indapamide in hypertension in daily practice." | 5.12 | Efficacy and tolerability of the perindopril/indapamide combination therapy for hypertension: the PRIMUS study. ( Holzgreve, H; Risler, T; Trenkwalder, P, 2006) |
| "investigate and compare the effect of valsartan and indapamide on inflammatory cytokines in hypertension." | 5.12 | Effects of valsartan and indapamide on plasma cytokines in essential hypertension. ( Sun, ZL; Wang, YJ; Xie, QY; Yang, TL, 2006) |
| "Indapamide SR is not less effective than enalapril in reducing microalbuminuria and blood pressure in patients aged >65 years of age with type 2 diabetes and hypertension." | 5.12 | Efficacy of indapamide SR compared with enalapril in elderly hypertensive patients with type 2 diabetes. ( Amouyel, P; Asmar, R; Fernandez, M; Finizola, B; Gallois, Y; Halabe, A; Hermansen, K; Ionescu-Tirgoviste, C; Jermendy, G; Kokot, F; Marre, M; Mion, D; Moyseev, V; Ollivier, JP; Opie, L; Puig, JG; Ruiz, M; Saldanha, MH; Scheen, A; Tuomilehto, J; Williams, B, 2007) |
| "In this study, 101 patients with mild essential hypertension were randomly assigned to an 8-week period of monotherapy with enalapril 10 mg a day or indapamide 2." | 5.12 | Superior effect of an angiotensin-converting enzyme inhibitor over a diuretic for reducing aortic systolic pressure. ( He, XY; Jiang, XJ; Liu, LS; O'Rourke, MF; Zhang, YQ, 2007) |
| "Combination of enalapril and indapamide is effective and safe in outpatients with arterial hypertension of the first-third degree and baseline high rigidity of the vascular wall." | 5.12 | [Clinical and vascular effects of ACE inhibitor enalapril in combination with thiaside-like diuretic indapamide in hypertensive outpatients. Results of the multicenter trial POEMA]. ( Abrosimova, OIu; Ageev, FT; Belenkov, IuN; Fomin, IV; Gapon, LI; Katel'nitskaia, LI; Khokhlov, RA; Kondari, AO; Orolova, IaA; Patrusheva, IF; Volkova, EG, 2007) |
| "To study the indices of nonspecific inflammation (C-reactive protein--CRP, interleukine 6--IL-6) in patients with essential hypertension (EH) as compared to a circadian profile of blood pressure (BP); changes of CRP in the course of therapy with indapamide-retard and ACE inhibitor perindopril." | 5.12 | [The activity of nonspecific inflammation in hypertensive patients]. ( Dmitriev, VA; Masenko, VP; Oshchepkova, EV; Rogoza, AN; Titiov, VN, 2007) |
| "Therapy with the use of a fixed combination of perindopril and indapamide was prescribed to 22 patients with metabolic syndrome and I - II degree hypertension for 16 weeks." | 5.12 | [Effect of a fixed combination of perindopril and indapamide on 24-hour blood pressure profile, morpho-functional parameters of the heart, heart rate variability, functional state of the kidney, and quality of life in patients with arterial hypertension c ( Statsenko, ME; Zemlianskaia, MM, 2007) |
| "The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) showed that blood pressure lowering reduced stroke risk in patients with a history of cerebrovascular events." | 5.11 | Effects of a perindopril-based blood pressure-lowering regimen on the risk of recurrent stroke according to stroke subtype and medical history: the PROGRESS Trial. ( Anderson, C; Bousser, MG; Chalmers, J; Chapman, N; Colman, S; Davis, S; Donnan, G; Huxley, R; MacMahon, S; Neal, B; Warlow, C; Woodward, M, 2004) |
| "625 mg versus atenolol 50 mg on BP parameters and variability over 24 h in patients with hypertension." | 5.11 | Twenty-four-hour ambulatory blood pressure monitoring efficacy of perindopril/indapamide first-line combination in hypertensive patients: the REASON study. ( Asmar, R; Battegay, E; Chamontin, B; De Leeuw, PW; Duprez, D; Hitzenberger, G; Mallion, JM; O'Brien, E; O'Rourke, MF; Rahn, KH; Romero, R; Safar, ME, 2004) |
| "Analyses of the risks of stroke were conducted for subjects with and without diabetes, participating in a randomized, double-blind, placebo-controlled trial of a perindopril-based blood pressure lowering regimen in 6105 people with prior stroke or transient ischaemic attack (TIA), followed for a median of 3." | 5.11 | Reductions in the risks of recurrent stroke in patients with and without diabetes: the PROGRESS Trial. ( Berthet, K; Bousser, MG; Chalmers, JP; Colman, SA; MacMahon, SW; Neal, BC; Woodward, M, 2004) |
| "In the treatment of hypertension in subjects of African origins, although hydrochlorothiazide (HCTZ) is not as effective as calcium channel blockers, indapamide is superior to HCTZ." | 5.11 | Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry. ( Candy, GP; Essop, MR; Hlatshwayo, NM; Kachope, J; Libhaber, CD; Libhaber, EN; Norton, GR; Puane, MO; Sareli, P; Sliwa, K; Woodiwiss, AJ, 2004) |
| "To test whether microalbuminuria in patients with type 2 diabetes and hypertension is primarily dependent on the severity of hypertension, and to compare the effectiveness of two antihypertensive drugs with opposite effects on the renin-angiotensin system [the diuretic, indapamide sustained release (SR), and an angiotensin-converting enzyme inhibitor, enalapril] in reducing microalbuminuria." | 5.11 | Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study. ( Amouyel, P; Asmar, R; Fernandez, M; Finizola, B; Gallois, Y; Halabe, A; Hermansen, K; Ionescu-Tirgoviste, C; Jermendy, G; Kokot, F; Marre, M; Mion Júnior, D; Moyseev, V; Ollivier, JP; Opie, L; Puig, JG; Ruiz, M; Saldanha, MH; Scheen, A; Tuomilehto, J; Williams, B, 2004) |
| "A first line management of hypertension based on a low-dose combination of perindopril and indapamide allows the normalization of blood pressure in significantly more patients than a 'sequential monotherapy' strategy involving atenolol, losartan and amlodipine, and a 'stepped-care' strategy involving valsartan and hydrochlorothiazide." | 5.11 | Comparison of different therapeutic strategies in hypertension: a low-dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped-care approach. ( Andréjak, M; Duru, G; Laville, M; Mourad, JJ; Waeber, B; Zannad, F, 2004) |
| "Over the course of the long-term, 12-month follow-up study, indapamide SR was shown to be an effective and well tolerated antihypertensive therapy, even after a switch from amlodipine or hydrochlorothiazide, in patients aged 65 years-80 years with systolo-diastolic hypertension (SDH) or ISH." | 5.11 | Evaluation of long-term efficacy and acceptability of indapamide SR in elderly hypertensive patients. ( Abate, G; Calvo-Gomez, C; Emeriau, JP; Knauf, H; Leonetti, G; Pujadas, JO, 2005) |
| "To compare clinical efficacy and tolerance of fixed combinations of perindopril and indapamide (noliprel), capoten+hydrochlorotiaside (caposide) in arterial hypertension stage I-II of high and very high risk which failed prior monotherapy." | 5.11 | [Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk]. ( Brel', UA; Chaliabi, TA; Kapustin, IO; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VA, 2005) |
| "This study was a subsidiary analysis of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS)--a randomized, placebo-controlled trial that established the beneficial effects of blood pressure--lowering in a heterogeneous group of patients with cerebrovascular disease." | 5.11 | Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack. ( Anderson, C; Arima, H; Chalmers, J; Colman, S; Hart, RG; MacMahon, S; Neal, B; Rodgers, A; Woodward, M, 2005) |
| " The PICXEL study compared the efficacy of a strategy based on first-line combination with perindopril/indapamide versus monotherapy with enalapril in reducing left ventricular hypertrophy (LVH) in hypertensive patients." | 5.11 | Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study. ( Dahlöf, B; De Leeuw, PW; de Simone, G; Degaute, JP; Dubourg, O; García-Puig, J; Gosse, P; Guéret, P; Karpov, Y; Magometschnigg, D; Matos, L; Schmieder, R, 2005) |
| "The purpose of this study was to evaluate the effects of the angiotensin-converting enzyme (ACE) inhibitor enalapril and diuretic indapamide on the peripheral blood pressure and the central blood pressure in Chinese patients with essential hypertension." | 5.11 | [The comparison of the effect of enalapril and indapamide on the peripheral blood pressure and central blood pressure through pulse wave analysis]. ( Jiang, XJ; Li, QY; Liu, GZ; Liu, LS; Zhang, YQ, 2005) |
| "25 mg) (Noliprel forte) and captopril (50 mg) with hydrochlorothiazide (25 mg) (Capozide) were compared in a randomized study on 40 patients with I-II degree high and very high risk hypertension." | 5.11 | [Comparative efficacy of fixed dose combinations of perindopril with indapamide and captopril with hydrochlorothiazide in patients with high risk hypertension]. ( Brel', UA; Chaliabi, TA; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VV, 2005) |
| "Monotherapy with indapamide is associated with greater BP reduction and control and response rates than monotherapy with low-dose hydrochlorothiazide and may be an appropriate choice of antihypertensive diuretic therapy in black South African patients with mild to moderate hypertension." | 5.10 | Comparison of indapamide and low-dose hydrochlorothiazide monotherapy in black patients with mild to moderate hypertension. ( Candy, GP; Ngcezula, T; Radevski, IV; Sareli, P; Valtchanova, ZP; Wald, AM, 2002) |
| "The first fundamental study devoted to the reduction of microalbuminuria with a antihypertensive diuretic (indapamide SR) in type 2 diabetes with hypertension, the Marre study (NESTOR) was designed to demonstrate that this antihypertension agent could be an interesting therapeutic alternative by comparing its efficacy on microalbuminuria with that of enalapril 10 mg during a treatment period of 52 weeks." | 5.10 | [Treatment of hypertensive type 2 diabetes patients with microalbuminuria]. ( Marre, M, 2002) |
| "The aim of the study was to evaluate efficacy and tolerability of two different fixed combinations of an angiotensin-converting enzyme inhibitor and a diuretic: delapril+indapamide (D+I) and captopril+hydrochlorothiazide (C+H) administered for 6 months to patients with mild to moderate essential hypertension." | 5.10 | Evaluation of the efficacy and tolerability of the combination delapril plus indapamide in the treatment of mild to moderate essential hypertension: a randomised, multicentre, controlled study. ( Rizzoni, D; Rosei, EA, 2003) |
| "To evaluate the effect of the sustained-release formulation of indapamide (indapamide SR) in type 2 diabetic patients with mild-to-moderate hypertension and its possible side effects, particularly on glucose metabolism and lipid profiles." | 5.10 | Effect of indapamide SR in the treatment of hypertensive patients with type 2 diabetes. ( He, CT; Hsieh, AT; Hsieh, CH; Hung, YJ; Kuo, SW; Lian, WC; Wu, LY; Yang, TC, 2003) |
| "We conducted a prospective, randomized, open-label, blinded endpoint crossover study comparing the metabolic responses to the addition of either hydrochlorothiazide (HCTZ) or indapamide, in 18 diabetic hypertensive patients receiving ACE inhibitor monotherapy for hypertension." | 5.10 | Comparative metabolic effects of hydrochlorothiazide and indapamide in hypertensive diabetic patients receiving ACE inhibitor therapy. ( Gilbert, RE; Krum, H; Skiba, M, 2003) |
| "Two hundred and ninety-two patients with mild to moderate hypertension were divided into 4 groups at random and treated with compound Lingjiao Jiangya Pill, benazepril, amlodipine and indapamide respectively with a therapeutic course of 6 weeks." | 5.09 | [CEA comprehensive evaluation for Western and traditional Chinese hypotensive drugs]. ( He, BR; Li, L; Wang, Y, 2001) |
| "The effectiveness as well as the metabolic effects of the combination of diuretics [hydrochlorothiazide (HCT) vs indapamide (IND)] and perindopril (P) in 14 patients (7 male, 7 female) aged 37-62 years with mild idiopathic hypertension were studied." | 5.09 | Effectiveness and metabolic effects of perindopril and diuretics combination in primary hypertension. ( Elisaf, MS; Kalaitzidis, R; Katopodis, K; Papagalanis, N; Pappas, H; Siamopoulos, KC; Theodorou, J, 1999) |
| "The primary aim of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) is to determine the effects of a long-term angiotensin converting enzyme (ACE)-inhibitor-based blood-pressure-lowering regimen on the risk of stroke among patients with a history of stroke or transient ischaemic attack (TIA)." | 5.09 | PROGRESS - Perindopril Protection Against Recurrent Stroke Study: characteristics of the study population at baseline. Progress Management Committee. ( , 1999) |
| "To establish the optimal dose of the perindopril/indapamide combination (Per/Ind) in the treatment of mild or moderate hypertension." | 5.09 | Fixed low-dose combination therapy in hypertension--a dose response study of perindopril and indapamide. ( Asmar, R; Leenen, FH; Myers, MG; Safar, M, 2000) |
| "Following a single-blind, placebo run-in period of 4 weeks, patients [65-85 years, with mild-to-moderate essential hypertension or isolated systolic hypertension (ISH)] were randomized to receive one tablet of perindopril 2 mg/indapamide 0." | 5.09 | Long-term efficacy of a new, fixed, very-low-dose angiotensin-converting enzyme-inhibitor/diuretic combination as first-line therapy in elderly hypertensive patients. ( Castaigne, A; Chalmers, J; Chastang, C; Morgan, T, 2000) |
| "The LIVE study (left ventricular hypertrophy regression, indapamide versus enalapril) was a 1 year, prospective, randomized, double-blind study." | 5.09 | Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study. ( Chastang, C; de Leeuw, PW; Degaute, JP; Dubourg, O; Gosse, P; Guéret, P; Karpov, Y; Motz, W; Palma-Gamiz, JL; Pessina, A; Sheridan, DJ; Zannad, F, 2000) |
| "5 mg shows similar antihypertensive efficacy to amlodipine 5 mg and hydrochlorothiazide 25 mg in elderly hypertensive patients, while in patients with isolated systolic hypertension, indapamide SR 1." | 5.09 | A comparison of indapamide SR 1.5 mg with both amlodipine 5 mg and hydrochlorothiazide 25 mg in elderly hypertensive patients: a randomized double-blind controlled study. ( Abate, G; Calvo-Gomez, C; Chastang, C; Emeriau, JP; Knauf, H; Leonetti, G; Pujadas, JO, 2001) |
| "625 mg (P/I) compared with the angiotensin II antagonist losartan 50 mg (L50) in the treatment of essential hypertension." | 5.09 | Antihypertensive efficacy and tolerability of low-dose perindopril/indapamide combination compared with losartan in the treatment of essential hypertension. ( Chanudet, X; De Champvallins, M, 2001) |
| "To study effects of perindopril, indapamid and their combination on stratification of essential hypertension (EH) risk factors." | 5.09 | [Effects of perindopril and its combination with indapamide on risk stratification in patients with hypertension]. ( Ol'binskaia, LI; Zheleznykh, EA, 2001) |
| "625 mg indapamide in essential hypertension." | 5.09 | Clinical benefit of very-low-dose perindopril-indapamide combination in hypertension. ( Laurent, S, 2001) |
| "To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)." | 5.08 | Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995) |
| "The long-term effects of indapamide or hydrochlorothiazide on blood pressure and renal function were examined in patients with impaired renal function and moderate hypertension." | 5.08 | Comparison between the effects of indapamide and hydrochlorothiazide on creatinine clearance in patients with impaired renal function and hypertension. ( Gadallah, M; Madkour, H; Massry, SG; Plante, GE; Riveline, B, 1995) |
| "25 mg) of indapamide (Lozol, Rhône-Poulenc Rorer Pharmaceuticals, Collegeville, PA) was evaluated in 222 elderly patients (> or = 50 years) with mild to moderate essential hypertension in a multicenter, randomized, double-blind, parallel-group clinical trial." | 5.08 | Efficacious response with lower dose indapamide therapy in the treatment of elderly patients with mild to moderate hypertension. ( Codispoti, J; Curry, C; Ferdinand, K; Jain, AK; Jallad, NS; McNally, C; Schnaper, HW; Stokes, A; Toth, PD; Weidler, D, 1995) |
| "Indapamide is a diuretic prescribed in the treatment of hypertension at the dosage of 2." | 5.08 | [Therapeutic benefit of a low dose of indapamide: results of a double-blind against placebo European controlled study]. ( Asmar, R; Barrandon, S; Brault, Y; Bruxelles, MC; Chastang, C; de Cordoue, A; Guez, D; Malbezin, M, 1995) |
| "This report describes the effects of indapamide versus transdermal clonidine on left ventricular hypertrophy (LVH) in hypertensive diabetic patients." | 5.08 | Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. ( Berk, LS; Tan, LG; Tan, SA, 1996) |
| "The long-term effects of indapamide or hydrochlorothiazide on blood presssure and renal function were examined in patents with impaired renal function and moderate hypertension." | 5.08 | Indapamide is superior to thiazide in the preservation of renal function in patients with renal insufficiency and systemic hypertension. ( Gadallah, M; Madkour, H; Massry, SG; Plante, GE; Riveline, B, 1996) |
| " The present multicenter open study was designed to test the effects of indapamide, a widely used nonthiazide diuretic, on LVH in patients with essential hypertension." | 5.08 | Regression of left ventricular hypertrophy in patients with essential hypertension. Results of 6 month treatment with indapamide. ( Balazovjech, I; Barrandon, S; Brault, Y; Brown, R; Curry, CL; de Cordoüe, A; Galinier, F; Guez, D; Honos, G; Mariani, M; Olivan, J; Robinson, H; Ruddy, TD; Sami, M; Touzek, F, 1996) |
| "We conclude that the safety and efficacy of perindopril + indapamide, captopril + hydrochlorothiazide and enalapril + hydrochlorothiazide were equivalent after 8 weeks of treatment in patients with mild to moderate hypertension." | 5.08 | An equivalence study of the safety and efficacy of a fixed-dose combination of perindopril with indapamide versus fixed-dose combinations of captopril with hydrochlorothiazide and enalapril with hydrochlorothiazide in the treatment of hypertension. ( Brault, Y; Chastang, C; Di Perri, T; Guez, D; Laurandin, I; Luccioni, R; Redon, J; Sever, PS, 1995) |
| "The LIVE (Left Ventricular Hypertrophy: Indapamide Versus Enalapril) study is an ongoing multicenter, double-blind, controlled study of regression of echocardiographic left ventricular mass index in hypertensive patients with left ventricular hypertrophy (left ventricular mass indexes > 100 g/m2 for women and > 120 g/m2 for men) treated for 1 year with 1." | 5.08 | Centralized echocardiogram quality control in a multicenter study of regression of left ventricular hypertrophy in hypertension. ( Barrandon, S; Beauchet, A; de Cordoüe, A; Dubourg, O; Gosse, P; Guéret, P; Guez, D, 1998) |
| "5 mg SR formulation of indapamide has an improved antihypertensive efficacy : safety ratio, which is in accordance with international recommendations for the use of low-dose antihypertensive drugs and diuretics in first-line therapy of hypertension." | 5.08 | Low-dose antihypertensive therapy with 1.5 mg sustained-release indapamide: results of randomised double-blind controlled studies. European study group. ( Ambrosioni, E; de Cordoüe, A; Degaute, JP; Guez, D; MacMahon, M; Malin, PL; Pujol, DR; Safar, M, 1998) |
| "5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)." | 5.07 | Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993) |
| "Indapamide (Lozol), an indoline antihypertensive drug with diuretic and vasodilating activities, was evaluated in 195 patients with mild to moderate essential hypertension (sitting DBP between 95 and 110 mmHg) in a multicentre, randomised, double-blind, parallel-group design trial." | 5.07 | Lower dose diuretic therapy in the treatment of patients with mild to moderate hypertension. ( Codispoti, J; Ferdinand, K; Flamenbaum, W; Hall, WD; Herron, J; Jain, AK; Marbury, T; Weber, MA; Weidler, D; Weiss, R, 1994) |
| "Evaluate the clinical efficacy and quality of life of indapamide in patients with mild and moderate arterial systemic hypertension under indapamide." | 5.07 | [Hypertension and well-being: a study with indapamide]. ( Alfaiate, A; Carrageta, MO; Corrêa-Nunes, A; Gouveia-Oliveira, A; Macieira, L; Matias, F; Rodrigues, T, 1994) |
| "M-mode echocardiography was used in 80 patients with essential hypertension to study changes in the index of left ventricular mass during treatment over 3 years with reserpine, prazosin, indapamide and atenolol, separately or in combination." | 5.06 | The effect of chronic antihypertensive therapy on the index of left ventricular mass in patients with essential hypertension. ( Duman, EL; Komsuoğlu, B; Komsuoğlu, SS; Ozgür, O, 1989) |
| "The effect of long-term treatment with indapamide in platelet alpha 2-adrenoceptors has been evaluated in 10 patients with essential hypertension, in a double-blind, cross-over study with placebo." | 5.06 | Platelet alpha 2-adrenoceptor modifications induced by long-term treatment with indapamide in essential hypertension. ( Bardelli, M; Carretta, R; Cesanelli, R; Fabris, B; Fischetti, F; Giraldi, T; Greco, PL; Melchior, C; Muiesan, S; Pizzolitto, A, 1988) |
| "Arterial compliance, assessed by the ratio of stroke volume to pulse pressure, and baroreceptor sensitivity (Oxford method), were determined in ten patients with essential hypertension, treated with placebo or indapamide (2." | 5.06 | Arterial compliance and baroreceptor sensitivity after chronic treatment with indapamide. ( Bardelli, M; Bianchetti, A; Campanacci, L; Carretta, R; Fabris, B; Fischetti, F; Muiesan, S; Vran, F, 1988) |
| "One hundred forty-nine patients between 56 and 80 years of age with mild to moderate hypertension received indapamide (2." | 5.06 | Assessment of indapamide in elderly hypertensive patients with special emphasis on well-being. ( Ludwig, B; Weitz, T; Werning, C, 1988) |
| "The effects of indapamide and captopril on office and ambulatory blood pressure control and on general well-being were investigated in 30 active, randomly selected patients from 25 to 68 years old, with mild to moderate essential hypertension (diastolic blood pressure, 92 to 114 mm Hg)." | 5.06 | Analysis of well-being and 24-hour blood pressure recording in a comparative study between indapamide and captopril. ( Lacourciere, Y, 1988) |
| "5 mg indapamide was compared in patients with essential hypertension, known as responders to diuretic therapy." | 5.06 | Comparative study on the antihypertensive efficacy of torasemide and indapamide in patients with essential hypertension. ( Achhammer, I; Glocke, M; Metz, P; Spannbrucker, N, 1988) |
| " No increase in LDL-C was noted in 43 men (32 normal, 11 with mild hypertension) treated with indapamide, 2." | 5.05 | Effects of indapamide and various diuretics alone or combined with beta-blockers on serum lipoproteins. ( Bianchetti, MG; Mordasini, R; Weidmann, P, 1983) |
| "This study, carried out in three centers in the United States, investigated the antihypertensive effect of three dosages of indapamide in 87 patients with mild to moderate hypertension." | 5.05 | Multicenter dose-response study of the effect of indapamide in the treatment of patients with mild to moderate hypertension. ( Bolton, S; Capone, P; Neiss, ES; Reeves, RL; Vukovich, RA, 1983) |
| "A double-blind trial was carried out in 24 patients with mild hypertension to compare the efficacy and tolerability of indapamide with that of a standard thiazide diuretic, hydrochlorothiazide." | 5.05 | Indapamide in the treatment of essential arterial hypertension: results of a controlled study. ( Plante, GE; Robillard, C, 1983) |
| "Fifteen out-patients with moderate hypertension were randomly and sequentially treated with atenolol, indapamide and a combination of the two drugs after a wash-out period of at least 1 week and a 2-week placebo run-in period." | 5.05 | Indapamide and atenolol in the treatment of hypertension: double-blind comparative and combination study. ( De Divitiis, O; Di Somma, S; Fazio, S; Ligouri, V; Petitto, M, 1983) |
| "The effect of chronic treatment with indapamide on blood pressure (BP), baroreceptor sensitivity (BRS) and vascular reactivity (VR) were investigated in 10 patients with essential hypertension." | 5.05 | Effect of indapamide on the baroreceptor reflex in essential hypertension. ( Battilana, G; Bellini, G; Bianchetti, A; Campanacci, L; Carretta, R; Fabris, B; Tonutti, L, 1983) |
| "Twenty-four patients (average age 72 years) took part in a study of the effectiveness and tolerance of indapamide as medication for essential hypertension in elderly subjects." | 5.05 | Indapamide in the treatment of essential arterial hypertension in the elderly. ( Brems, H; Thomas, J; Van Hee, W, 1981) |
| "A total of 1600 patients with essential arterial hypertension was recruited from 10 countries, and treated with indapamide according to a common protocol." | 5.05 | International multicentre study of indapamide in the treatment of essential arterial hypertension. ( Desprat, J; Passeron, J; Pauly, N, 1981) |
| "1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 5.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
| "Sixteen patients with essential hypertension completed a double blind factorial trial comparing the effects of indapamide (2." | 5.05 | Effects of once daily indapamide and pindolol on blood pressure, plasma aldosterone concentration and plasma renin activity in a general practice setting. ( Bune, AJ; Chalmers, JP; Graham, JR; Grygiel, JJ; West, MJ; Wing, LM, 1982) |
| "Indapamide and methyldopa were compared in an open parallel study in patients with mild or moderate hypertension." | 5.05 | Indapamide in ambulant treatment of hypertension: a comparative study with alpha-methyldopa. ( Meine, H, 1981) |
| "A multi-centre open trial involving 150 cardiologists throughout France was undertaken to assess the efficacy and tolerance of indapamide in the treatment of essential hypertension." | 5.05 | The efficacy and tolerance of indapamide in essential hypertension: a multi-centre study in 981 patients. ( Abbou, CB, 1985) |
| "A controlled multicentre trial was organised to compare the effects of 20 mg Nifedipine tablets (N) and 2,5 mg Indapamide tablets (I) during a 4 months' treatment period after a placebo period, in 59 patients with moderate essential hypertension (n = 59)." | 5.05 | [Comparative effects of nifedipine and indapamide in the treatment of arterial hypertension]. ( Aubert, P; Chaignon, M; Guédon, J; Lucsko, M; Rapoud, JP, 1985) |
| " Fifty-three patients with mild essential hypertension (WHO groups I and II) in three medical centers were treated with either muzolimine or indapamide, which served as the reference preparation, in a randomised, double-blind study." | 5.05 | Clinical evaluation of muzolimine and indapamide during treatment for essential hypertension. ( Kirsten, R; Molz, KH; Nelson, K; Tzonev, I, 1985) |
| "5 mg/day indapamide, preceded and followed by 2 weeks of a placebo, led to a significant fall in pressure values and normalisation of diastolic pressure in a high percentage of 47 subjects, mostly with essential hypertension, in a controlled multi-centre trial." | 5.04 | [Controlled multicentric trial of the antihypertensive agent indapamide]. ( Abate, G; Gragnoli, G; Guerrini, M, 1977) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 4.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "A systematic literature search is undertaken for supporting the pharmacological proprieties and clinical efficacy of perindopril in the treatment of hypertension." | 4.87 | Perindopril for the treatment of hypertension. ( Ghiadoni, L, 2011) |
| " Pregabalin seems to provide clinically benefit to patients with fibromyalgia." | 4.85 | [Innovations in ambulatory care]. ( Bodenmann, P; Chapuis, T; Cornuz, J; de Bosset, V; Jaunin-Stalder, N; Marguerat, I; Nanchen, D; Pasche, O, 2009) |
| "We searched MEDLINE (1966-April 2003), EMBASE (1980-March 2003), BIOSIS (1999-December 2002), and the Cochrane Library, using the medical subject headings with the search terms perindopril, indapamide, hypertension, randomized controlled trials, randomly, random, randomization, perindopril-indapamide, essential hypertension, and primary hypertension." | 4.82 | A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension. ( An, N; Kang, S; Ren, M; Wu, YF, 2004) |
| "The fixed low-dose combination of the ACE inhibitor perindopril and the non-thiazide diuretic indapamide has been evaluated in the management of patients with mild to moderate hypertension." | 4.81 | Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. ( Cheer, SM; Goa, KL; Matheson, AJ, 2001) |
| "Black women with established essential hypertension, without renal insufficiency or diabetes mellitus, were withdrawn from their usual antihypertensive therapy for 2-3 weeks prior to entry into a study to evaluate pertinent biochemical and mineral effects of indapamide treatment." | 4.78 | Biochemical, endocrine, and mineral effects of indapamide in black women. ( Beall, SP; Carr, AA; Feldman, DS; Feldman, EB; Hames, CG; Nichoalds, GE; Prisant, LM, 1990) |
| "Although indapamide has been used for many years as a first-line treatment of hypertension, it is only recently that some of its activities on the changes of the cardiovascular system, brought on by age and high blood pressure, have been studied." | 4.78 | Cardiovascular protective properties of indapamide. ( Brackman, F; Campbell, DB, 1990) |
| "This study evaluated the effectiveness of treatment with an indapamide/amlodipine single-pill combination (SPC) in outpatients with uncontrolled isolated systolic hypertension (ISH) aged over 55 years in real-life clinical practice." | 4.12 | Effectiveness of indapamide/amlodipine single-pill combination in patients with isolated systolic hypertension: post-hoc analysis of the ARBALET study. ( Goreva, LA; Karapetyan, LV; Kobalava, ZD; Kolesnik, EL; Shavarova, EK, 2022) |
| "A total of 198 patients with hypertension in ambulatory care who had been on fixed-dose combination of perindopril arginine, indapamide, and amlodipine for at least 4 weeks were included." | 4.12 | Use of Perindopril Arginine/Indapamide/Amlodipine in the Management of Hypertension in Two Sub-Saharan African Island Countries of Madagascar and Mauritius. ( Ackbarkhan, A; Mbanya, A; Mbanya, JC; Mittoo, MY; Ramamonjisoa, HA; Ramilitiana, B; Ranivoharisoa, EM; Ratsimbazafy, SJN, 2022) |
| "Our objective was to determine the effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in a broad range of patient profiles, including subgroups with varying hypertension severity, age and cardiovascular risk profiles." | 4.02 | Effectiveness of Perindopril/Indapamide Single-Pill Combination in Uncontrolled Patients with Hypertension: A Pooled Analysis of the FORTISSIMO, FORSAGE, ACES and PICASSO Observational Studies. ( Brzozowska-Villatte, R; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021) |
| " Triplixam is used to treat systemic hypertension and contains amlodipine, indapamide and perindopril arginine as active ingredients which might have induced the sudden myopia." | 3.96 | Acute bilateral myopia induced by Triplixam: a case report. ( Jaruseviciene, R; Sirvydyte, G, 2020) |
| "to investigate the impact of indapamide / perindopril single-pill combination (I / P SPC) on arterial stiffness parameters, blood pressure (BP) level and BP variability (BPV) in middle-aged patients with stage II grade 1-2 essential arterial hypertension (EAH)." | 3.91 | [Single Pill Indapamide and Perindopril Arginine Combination: Optimal Coupling of Vascular Protection and Hemodynamic Risk Factors Reduction in Patients with Essential Arterial Hypertension]. ( Borisova, EV; Kochetkov, AI; Ostroumova, OD, 2019) |
| "Although both regimens were effective for reducing BP, increasing amlodipine to 10 mg daily controlled hypertension without elevation of serum uric acid." | 3.88 | Prospective direct comparison of antihypertensive effect and safety between high-dose amlodipine or indapamide in hypertensive patients uncontrolled by standard doses of angiotensin receptor blockers and amlodipine. ( Okamura, K; Okuda, T; Shirai, K; Totake, N; Urata, H, 2018) |
| "To study the effectiveness of a fixed combination of perindopril and amlodipine, with the subsequent addition of indapamide-retard in male patients with arterial hypertension (AH), obesity and severe sleep apnea (OSAS)." | 3.88 | The effectiveness of combination antihypertensive therapy in patients with arterial hypertension and additional risk factors: obesity and obstructive sleep apnea syndrome. ( Chazova, IE; Elfimova, EM; Litvin, AY, 2018) |
| "We conducted an analysis of the action in diabetes and vascular disease: preterax and diamicron-MR controlled evaluation ADVANCE and perindopril protection against recurrent stroke study PROGRESS trials, including 14 684 participants allocated combination therapy or placebo." | 3.85 | Side effects and tolerability of combination blood pressure lowering according to blood pressure levels: an analysis of the PROGRESS and ADVANCE trials. ( Atkins, ER; Chalmers, J; Cooper, M; Hamet, P; Harrap, S; Hirakawa, Y; Lees, K; Liu, L; Mancia, G; Marre, M; Perkovic, V; Poulter, N; Rodgers, A; Salam, A; Williams, B; Woodward, M, 2017) |
| "to assess the potential of fixed perindopril/indapamide combination (FPIC) to improve angioprotection in patients with arterial hypertension (AP) with various efficacy of preceding therapy with combination of losartan and hydrochlorothiazide (HCTZ)." | 3.85 | [Optimization of Control of Blood Pressure, Metabolic Disorders and Target Organs Protection With Fixed Perindopril and Indapamide Combination in Treated Patients With Arterial Hypertension]. ( Chumachek, EV; Hripaeva, VJ; Ledyaeva, AA; Nedogoda, SV; Palashkin, RV; Salasyuk, AS; Smirnova, VO; Tsoma, VV, 2017) |
| "In enhancing the effectiveness of the treatment of patients with hypertension was decisive simplification of drug therapy through the use of a fixed combination of perindopril A/indapamide." | 3.83 | [How to Increase the Effectiveness of Antihypertensive Therapy in Clinical Practice: Results of the Russian Observational Program FORSAZH]. ( Deev, AD; Glezer, MG, 2016) |
| "The study was aimed at evaluating the efficacy and usability of a dispersible form of perindopril in patients with arterial hypertension (HT) in clinical practice." | 3.83 | [Effectiveness of Dispersible Forms of Perindipril in Patients With Uncontrolled Arterial Hypertension in Clinical Practice]. ( Fendrikova, AV; Skibitskiy, VV, 2016) |
| " FC, two extreme approaches are presented: with difference in effectiveness due to improved adherence to the treatment estimated from published studies on other molecules used in hypertension such as SPCs and FCs - the base-case approach (1); and assuming no difference of effectiveness or adherence between SPC and FC of indapamide and amlodipine - the conservative approach (2)." | 3.81 | Economic evaluation of single-pill combination of indapamide and amlodipine in the treatment of arterial hypertension in the Polish setting. ( Borowiec, Ł; Filipiak, KJ; Holko, P; Kawalec, P; Stawowczyk, E, 2015) |
| "A total of 4,731 patients at high or very high cardiovascular risk with hypertension that was not properly controlled [ , and for [corrected] whom study treatment (fixed-dose perindopril 10 mg/indapamide 2." | 3.80 | Antihypertensive efficacy of triple combination perindopril/indapamide plus amlodipine in high-risk hypertensives: results of the PIANIST study (Perindopril-Indapamide plus AmlodipiNe in high rISk hyperTensive patients). ( Tóth, K, 2014) |
| " Our study evaluated the efficacy of triple therapy with perindopril, amlodipine, and indapamide sustained release (SR) in patients with uncontrolled hypertension on previous antihypertensive therapy." | 3.80 | Triple combination therapy in hypertension: the antihypertensive efficacy of treatment with perindopril, amlodipine, and indapamide SR. ( Páll, D; Szabó, Z; Szántó, I, 2014) |
| "Triplixam is a fixed dose combination of three well known antihypertensive agents, with complementary activities, to control blood pressure in patients with arterial hypertension: perindopril, an angiotensin converting enzyme inhibitor, indapamide, a diuretic whith thiazide-like effects but also specific properties, and amlodipine, a long-acting calcium antagonist of the dihydropyridine family." | 3.80 | [Fixed dose combination perindopril-indapamide-amlodipine (Triplixam) for the treatment of arterial hypertension]. ( Krzesinski, JM; Lancellotti, P; Scheen, AJ, 2014) |
| "Patients with echocardiographic left ventricular hypertrophy at baseline (n = 124) showed greater reduction of left ventricular mass index with Per/Ind (-11." | 3.80 | [Arterial stiffness, wave reflections and myocardial protection: the REASON project]. ( London, GM, 2003) |
| "Long-term treatment of patients with essential hypertension (EH) and autonomic dysfunction (sympathicotonia type) with lisinopril in combination with indapamide augmented activity of humoral systems and improved heart rate variability." | 3.79 | [Optimization of pharmacotherapy in patients with essential hypertension with neurohumoral modulators with consideration of data on heart rate variability]. ( Bakhshaliev, AB; Kakhramanova, SM, 2013) |
| "The influence of vascular remodeling and endothelial vasomotor function on the efficacy of indapamide retard was studied in 92 patients (49 men and 43 women) with stage I-II hypertensive disease and grade I-II arterial hypertension by observation of dynamics of the results of 24 hour AP monitoring and heart rhythm variability (HRV), cardio- and vasoprotective efects." | 3.78 | [The influence of vascular remodeling and endothelial vasomotor function on the efficacy of indapamide retard in patients with hypertensive disease]. ( Iskenderov, BG; Kazantseva, LV; Saushkina, SV; Sisina, ON, 2012) |
| "The aim of the study was to investigate the dynamics of arterial stiffness and endothelial function parameters under the influence of perindopril arginine and indapamide fixed combination in arterial hypertension (AH) patients." | 3.78 | [Vascular effects of perindopril arginine and indapamide fixed combination in patients with arterial hypertension]. ( Golubeva, LV; Logovikova, SI; Protasov, KV; Reshina, IV; Sinkevich, DA; Zhizhko, NV, 2012) |
| "The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis." | 3.77 | The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011) |
| "To study ways of realization of pleiotropic effects of treatment with low-dose combination of perindopril arginine with indapamide in hypertensive patients with metabolic syndrome (MS)." | 3.77 | [Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome]. ( , 2011) |
| "Indapamide(1 mg) was given daily for 3 months and was then given every other day for 3 months to patients whose hypertension was poorly controlled with angiotensin II receptor blocker (ARB)-based treatment." | 3.76 | Effects of additional administration of low-dose indapamide on patients with hypertension treated with angiotensin II receptor blocker. ( Kusunose, K; Mishiro, Y; Sata, M; Yamada, H, 2010) |
| "The Hypertension in the Very Elderly Trial (HYVET) is a randomized double-blind trial of active antihypertensive treatment (indapamide 1." | 3.75 | Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET). ( Banya, W; Beckett, NS; Bulpitt, CJ; Burch, L; Dumitrascu, D; Fletcher, AE; Liu, L; Nikitin, Y; Peters, R; Staessen, JA; Stoyanovsky, V; Wang, JG, 2009) |
| "We assessed effect of antihypertensive drugs from various classes on humoral parameters of endothelial function - levels of asymmetrical dimethyl-arginine (ADMA) and metabolites of nitrous oxide (MNO) - in 106 patients with I-II degree arterial hypertension before and after 2 weeks of treatment." | 3.75 | [Effect of antihypertensive drugs on some humoral parameters of endothelial function]. ( Galiavich, AS; Galiavich, RA; Khamidullina, AR, 2009) |
| "The effects of indapamide, a thiazide-like diuretic, and captopril, an angiotensin-converting enzyme inhibitor, on spontaneous hypertension and the development of left ventricular hypertrophy (LVH), nitric oxide generation and oxidant status were investigated." | 3.75 | Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension. ( Jendekova, L; Paulis, L; Pechanova, O; Simko, F; Sladkova, M; Vranková, S, 2009) |
| " Results from HYVET (Hypertension in the Very Elderly Trial) showed that, at 2-year follow-up, antihypertensive drug therapy with indapamide, plus perindopril if needed, reduced fatal or nonfatal stroke by 30%, fatal stroke by 39%, all-cause mortality by 21%, cardiovascular death by 23%, and heart failure by 64%." | 3.74 | Older age should not be a barrier to the treatment of hypertension. ( Aronow, WS, 2008) |
| "5 mg of indapamide retard with or without addition of 2-4 mg of perindopril, 30% lowering of risk of development of fatal and nonfatal stroke (95% confidence interval [CI] -1 to 51, p=0." | 3.74 | [Arterial hypertension in persons older than 80 years: the problem can be successfully solved]. ( Batyraliev, TA; Fettser, DV; Ishlek, M; Preobrazhenskiĭ, DV; Sidorenko, BA, 2008) |
| "In patients with hypertension despite antihypertensive therapy, indapamide SR significantly reduced BP with a good acceptability profile." | 3.74 | Antihypertensive efficacy of indapamide SR in hypertensive patients uncontrolled with a background therapy: the NATIVE study. ( Akram, J; Donnelly, R; Mahmood, M; Sheikh, UE, 2007) |
| " While randomized trials have demonstrated that blood pressure lowering reduces vascular complications in subjects with type 2 diabetes and hypertension, ADVANCE was designed to determine whether the addition of a fixed combination of perindopril and indapamide, on top of comprehensive and effective cardiovascular treatments and glucose control therapy, would produce further benefits, irrespective of the initial blood pressure." | 3.74 | Advances in reducing the burden of vascular disease in type 2 diabetes. ( Chalmers, J; Joshi, R; Patel, A, 2008) |
| " We hypothesized that 1) hypertension abrogates postnatal vasculogenesis, and 2) antihypertensive treatment based on the combination of perindopril (angiotensin-converting enzyme inhibitor) and indapamide (diuretic) may counteract hypertension-induced alteration in progenitor cell-related effects." | 3.74 | Combination of the angiotensin-converting enzyme inhibitor perindopril and the diuretic indapamide activate postnatal vasculogenesis in spontaneously hypertensive rats. ( Cochain, C; Duriez, M; Lévy, BI; Loinard, C; Mees, B; Silvestre, JS; Vilar, J; You, D, 2008) |
| "The Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS) showed the efficacy of blood pressure reduction in secondary stroke prevention." | 3.74 | Stroke secondary prevention and blood pressure reduction: an observational study of the use of PROGRESS therapy. ( Bugnicourt, JM; Canaple, S; Chillon, JM; Godefroy, O; Lamy, C, 2008) |
| "To compare efficacy of use of the blocker of aldosteron receptors spironolactone and diuretic indapamide in low-renin arterial hypertension (AH), their action on blood pressure, serum concentrations of sodium, potassium, creatinine, plasmic renin activity (PRA), plasmic aldosteron concentration (PAC)." | 3.73 | [Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. ( Bagdonas, G; Kazanavichus, G; Naudzhunas, A; Yankauskene, L, 2006) |
| "Patients (n=50) with essential hypertension were given either indapamide-retard (1." | 3.73 | [Comparative assessment of hypotensive, metabolic, and endothelial effects of indapamide-retard and hydrochlorothiazide in patients with essential hypertension]. ( Golevtsova, ZSh; Nazarov, AG; Potapov, VV; Pritykina, TV; Protskiĭ, IA; Semenkin, AA; Zhivilova, LA, 2006) |
| "To assess changes of blood pressure (BP) and processes of cardiovascular remodeling during treatment of previously untreated patients with hypertension with fixed low dose combination of perindopril and indapamide." | 3.72 | [Effect of fixed low dose combination of perindopril and indapamide on processes of cardiovascular remodeling in previously untreated patients with hypertension]. ( Anisimova, LP; Ivanenko, VV; Legkiĭ, AV; Lopatin, IuM; Riazantseva, NV; Semenova, NV, 2004) |
| "To study therapy with indapamide impairing carbohydrate metabolism in essential hypertension patients and achieve earlier prevention, diagnoses and treatment of diabetes induced by indapamide." | 3.72 | Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports). ( Jian-Li, Q; Jian-Liang, Z; Jiang, C; Rong-Liang, X; Xing, Z; Yong-Wen, Q, 2004) |
| "Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp)." | 3.71 | Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment. ( Bacchelli, B; Biagini, G; Contri, MB; Miselli, M; Pedrazzi, G; Taparelli, F, 2002) |
| "PROGRESS ("Perindopril pROtection aGainst REcurrent Stroke Study") demonstrated that blood-pressure lowering treatment with perindopril, an angiotensin converting enzyme inhibitor (combined with the diuretic agent indapamide when necessary), reduces the risk of stroke by 28% (95% CI: 17-38, p < 0." | 3.71 | [Clinical study of the month. Secondary prevention of cerebrovascular accident with perindopril: the PROGRESS study]. ( Scheen, AJ, 2001) |
| "A 66-year-old hypertensive male with acute intracerebral hemorrhage developed acute hyponatremic coma 3 days after the addition of enalapril and a combination of amiloride and a thiazide diuretic to his hypotensive regimen." | 3.70 | Acute hyponatremic encephalopathy after a cerebrovascular accident. ( Moussa, NA; Osman, AR; Yahya, TM, 1998) |
| " Indapamide (IDP), a sulfonamide diuretic related to thiazides, is used to treat hypertension." | 3.70 | The diuretic indapamide increases bone mass and decreases bone resorption in spontaneously hypertensive rats supplemented with sodium. ( De Vernejoul, MC; Graulet, AM; Lalande, A; Roux, C; Schiavi, P, 1998) |
| "This randomized, double-blind, placebo-controlled, parallel-group study evaluated the efficacy and safety of single daily dose diltiazem extended-release (XR) and indapamide, given alone and combined, in 255 male and 170 female patients with mild to moderate hypertension." | 3.70 | Ambulatory blood pressure profiles in patients treated with once-daily diltiazem extended-release or indapamide alone or in combination. ( Prisant, LM, 2000) |
| "These experiments suggest that chronic combined treatment with low doses of an angiotensin converting enzyme inhibitor and a diuretic such as indapamide may be of value in the treatment of hypertension." | 3.69 | Fixed-dose combination of perindopril with indapamide in spontaneously hypertensive rats: haemodynamic, biological and structural effects. ( Guez, D; Henry, JP; Joannides, R; Mace, B; Mulder, P; Richard, V; Schiavi, P; Thuillez, C, 1996) |
| "The aim was to compare the effects of two diuretics, indapamide and hydrochlorothiazide, on cardiac hypertrophy in stroke prone spontaneously hypertensive rats (SHR-SP)." | 3.68 | Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat. ( Contard, F; Glukhova, M; Guez, D; Marotte, F; Narcisse, G; Rappaport, L; Samuel, JL; Schatz, C; Swynghedauw, B, 1993) |
| " In this study, 21 patients with noninsulin-dependent diabetes and hypertension (11 with normoalbuminuria and 10 with microalbuminuria), who were comparable for age, duration of diabetes and hypertension, were treated with indapamide, 2." | 3.68 | Efficacy of antihypertensive treatment with indapamide in patients with noninsulin-dependent diabetes and persistent microalbuminuria. ( Frontoni, S; Gambardella, S; Gargiulo, P; Grazia Felici, M; Menzinger, G; Morano, S; Spallone, V, 1990) |
| "Twenty-four-hour blood pressure (BP) monitoring with a noninvasive device (Kontron) has been used to assess the effect of a single dose of indapamide in a group of patients with essential hypertension." | 3.68 | Twenty-four-hour blood pressure monitoring and effects of indapamide. ( Mora, J; Ocon, J, 1990) |
| "Renal plasma flow (RPF), glomerular filtration rate (GFR), arginine vasopressin in plasma (AVP), free water clearance (CH2O) and blood pressure (BP) were determined in 11 patients with essential hypertension at the end of 3 consecutive periods of observation each of 6 of weeks duration; indapamide 2." | 3.67 | Effect of indapamide on renal plasma flow, glomerular filtration rate and arginine vasopressin in plasma in essential hypertension. ( Danielsen, H; Pedersen, EB; Spencer, ES, 1984) |
| "The effects of indapamide on diabetic patients with micro-albuminuria were evaluated in a multicentre study to assess the advantages of this compound in long-term renal protection." | 3.67 | Hypertension and micro-albuminuria in diabetic patients taking indapamide. ( Blümner, E; Janka, HU; Mehnert, H; van Michel, A; Weitz, T, 1989) |
| "In a group of 17 patients with mild hypertension the antihypertensive effect of Metipamide VUFB was investigated." | 3.67 | [Antihypertensive therapy using metipamide VUFB]. ( Dzúrik, R; Sedláková, K, 1989) |
| "The effect of metipamide on the level of Na+ and K+ in erythrocytes was studied in patients with essential hypertension." | 3.67 | [The effect of metipamide on levels of sodium and potassium in erythrocytes]. ( Dzúrik, R; Molitorisová, M; Sedláková, K, 1989) |
| "The efficacy of captopril alone or in combination with indapamide was evaluated in 17 patients with severe hypertension (diastolic greater than 120 mmHg) previously treated with triple antihypertensive therapy, i." | 3.67 | Antihypertensive effect of indapamide given in conjunction with captopril in severe hypertension. ( Dimkovic, S; Kocijancic, M, 1986) |
| "The results of a study conducted using a new loop diuretic, Azosemide, on a group of 45 patients suffering from hypertension and oedema are reported." | 3.67 | [Diuretic and antihypertensive activity of azosemide]. ( Bartoli, E; Branca, GF; Faedda, R; Satta, A, 1985) |
| "Fourteen patients with untreated mild to moderate essential hypertension had, on average, an abnormally high cardiovascular reactivity to exogenous noradrenaline and angiotensin II, while plasma noradrenaline, renin activity, exchangeable body sodium, and blood volume were normal." | 3.66 | Correction of altered noradrenaline reactivity in essential hypertension by indapamide. ( Beretta-Piccoli, C; Glück, Z; Grimm, M; Keusch, G; Meier, A; Weidmann, P; Ziegler, W, 1983) |
| "A study was undertaken in 19 patients with benign to moderate essential hypertension to verify the effect of indapamide alone or combined with a beta-blocker on plasma renin activity, plasma aldosterone, serum potassium and urinary prostaglandins PGE2 and PGF2a." | 3.66 | Antihypertensive effect of indapamide with special emphasis on renal prostaglandin production. ( Belleau, LJ; Grose, JH; Langlois, S; LeBel, M, 1983) |
| "The hemodynamic effects of indapamide were evaluated in an open clinical trial of nine patients with mild to moderate hypertension." | 3.66 | A systemic hemodynamic evaluation of indapamide. ( Esente, P; Gensini, G; Giambartolomei, A, 1983) |
| "The effects of acute and chronic administration of indapamide on systemic and renal haemodynamics were studied in 10 patients with arterial essential hypertension." | 3.66 | Effects of the acute and chronic administration of indapamide on systemic and renal haemodynamics in essential hypertension. ( Anguas, MC; Degandarias, L; Meza, U; Nuñez-Poissot, E; Villarreal, H, 1983) |
| "Fourteen patients with moderately severe essential hypertension were treated for 8 weeks with indapamide 2,5 mg/d." | 3.66 | The antihypertensive effect of indapamide. ( Acosta-Barrios, T; Leary, WP; Reyes, AJ; Van der Byl, K, 1983) |
| "Indapamide is a new antihypertensive diuretic agent indicated for the treatment of hypertension and edema." | 3.66 | Pharmacokinetics and clinical pharmacology of indapamide. ( Caruso, FS; Szabadi, RR; Vukovich, RA, 1983) |
| "The antihypertensive effect and a non-invasive cardiovascular assessment of indapamide in patients with idiopathic hypertension have been investigated in an uncontrolled study." | 3.66 | Non-invasive cardiovascular assessment of indapamide in patients with essential hypertension. ( Dunn, FG; Hillis, WS; Lorimer, AR; Rae, AP; Tweddel, A, 1981) |
| "Eleven insulin-dependent and 30 maturity onset diabetics with essential hypertension were treated with indapamide for 4 and 9 months respectively, to assess its effect on blood sugar regulation." | 3.66 | Blood sugar regulation during treatment with indapamide in hypertensive diabetics. ( Courtois, H; Roux, P, 1981) |
| "The onset of DOCA-salt hypertension in male Sprague-Dawley rats was prevented during 11 weeks of oral treatment with indapamide (0." | 3.66 | The effects of long term oral treatment with indapamide on the development of DOCA-salt hypertension in rats: vascular reactivity studies. ( Hicks, PE, 1979) |
| " All patients were randomized to three groups based on the dosing schedule of chronopharmacotherapy: group 1 (n=59), patients receiving indapamide retard 1." | 3.01 | Cardioprotective potential of chronopharmacotherapy in patients with arterial hypertension who had a transient ischemic attack. ( Fendrikova, AV; Opolskaya, SV; Skibitsky, AV; Skibitsky, VV; Zabolotskich, TB, 2021) |
| "The Quadruple UltrA-low-dose tReaTment for hypErTension (QUARTET) double-blind, active-controlled, randomized clinical trial will examine whether ultra-low-dose quadruple combination therapy is more effective than guideline-recommended standard care in lowering blood pressure." | 3.01 | Ultra-low-dose quadruple combination blood pressure-lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol. ( Atkins, ER; Billot, L; Chalmers, J; Chow, CK; Hay, P; Hillis, GS; Neal, B; Nelson, M; Patel, A; Reid, CM; Rodgers, A; Schlaich, M; Usherwood, T; Webster, R, 2021) |
| "Weight loss is strongly recommended for overweight and obese adults with type 2 diabetes." | 2.94 | The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE. ( Chalmers, J; Hamet, P; Harrap, S; Lee, AK; Marre, M; Mcevoy, JW; Ohkuma, T; Selvin, E; Sharrett, AR; Wang, D; Warren, B; Williams, B; Woodward, M, 2020) |
| "Hypertension has a major associated risk for organ damage and mortality, which is further heightened in patients with prior cardiovascular events, comorbid diabetes mellitus, microalbuminuria and renal impairment." | 2.82 | The advantages of combination therapy on hypertension: development of immediate release perindopril-indapamide tablet and assessment of bioequivalence studies. ( İnce, I; Karasulu, E; Ölçer, A; Ölçer, M, 2016) |
| "Telmisartan was more effective, whereas indapamide had better pharmacoeconomic benefits." | 2.80 | Prevention of metabolic disorders with telmisartan and indapamide in a Chinese population with high-normal blood pressure. ( Liu, Z; Lu, F; Peng, J; Tang, M; Wang, Z; Zhang, H; Zhang, W; Zhao, Y; Zhong, M, 2015) |
| "The treatment with eplerenone significantly increased serum potassium levels, whereas the treatment with indapamide significantly decreased them." | 2.80 | Effects of a selective aldosterone blocker and thiazide-type diuretic on blood pressure and organ damage in hypertensive patients. ( Hayashi, S; Ishizuka, A; Iwashima, Y; Kawano, Y; Kishida, M; Nakamura, S; Ohta, Y; Yoshihara, F, 2015) |
| "A total of 11 140 patients with type 2 diabetes mellitus were randomly assigned to fixed combination of perindopril-indapamide (4/1." | 2.79 | Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial. ( Arima, H; Chalmers, J; Harrap, S; Hirakawa, Y; Mancia, G; Patel, A; Poulter, N; Williams, B; Woodward, M; Zoungas, S, 2014) |
| " Perindopril/indapamide dosage could be increased, from 5/1." | 2.79 | Efficacy of single-pill perindopril/indapamide in patients with hypertension and type 2 diabetes. ( Gorbat, TV; Netchessova, TA; Shepelkevich, AP, 2014) |
| "In patients with type 2 diabetes, moderate alcohol use, particularly wine consumption, is associated with reduced risks of cardiovascular events and all-cause mortality." | 2.79 | The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes. ( Blomster, JI; Chalmers, J; Chow, CK; Harrap, S; Hillis, GS; Li, Q; Mancia, G; Neal, B; Patel, A; Poulter, N; Williams, B; Woodward, M; Zoungas, S, 2014) |
| "Incident dementia was a secondary endpoint and was not significantly different between the two treatment groups." | 2.78 | Increased pulse pressure linked to dementia: further results from the Hypertension in the Very Elderly Trial - HYVET. ( Beckett, N; Bulpitt, C; Fagard, R; Fletcher, A; Forette, F; Pereira, L; Peters, R; Thijs, L; Wang, JG, 2013) |
| "Perindopril/indapamide is an effective and safe antihypertensive treatment in everyday medical practice." | 2.78 | Blood pressure and metabolic efficacy of fixed-dose combination of perindopril and indapamide in everyday practice. ( Farsang, C, 2013) |
| "11,140 participants with type 2 diabetes, from the ADVANCE trial, were randomized to perindopril-indapamide or matching placebo." | 2.77 | Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes. ( Beulens, JW; Chalmers, J; Cooper, ME; Grobbee, DE; Harrap, S; Kengne, AP; Mancia, G; Neal, B; Patel, A; Poulter, N; van der Schouw, YT; van Dieren, S; Woodward, M; Zoungas, S, 2012) |
| "depression is common in elderly people and may be associated with increased cardiovascular risk and incident dementia." | 2.75 | Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Fletcher, A; Grimley-Evans, J; McCormack, T; Nunes, M; Peters, R; Pinto, E; Potter, J; Swift, C, 2010) |
| "The increase in type 2 diabetes mellitus is associated to cardiovascular morbidity and mortality." | 2.75 | Management of high blood pressure in type 2 diabetes: perindopril/indapamide fixed-dose combination and the ADVANCE trial [corrected]. ( Ghiadoni, L, 2010) |
| "Treatment with perindopril/indapamide improves endothelium-dependent vasodilation in comparison with atenolol." | 2.74 | Fixed dose combination of perindopril and indapamide improves peripheral vascular function in essential hypertensive patients. ( Ghiadoni, L; Kardasz, I; Magagna, A; Salvetti, A; Taddei, S, 2009) |
| "25 mg with decreases in mean 24-h ambulatory BP from 24 to 48 h and 48 to 72 h after dosing being -11." | 2.73 | The impact of one or two missed doses on the duration of action of combined perindopril and indapamide. ( Leenen, FH; Myers, MG, 2007) |
| "Indapamide retard was metabolically neutral whereas hydrochlorothiazide increased the blood levels of triglycerides and glucose by 15." | 2.73 | [Possibilities of using indices of vascular wall function as markers of negative metabolic effects of treatment with thiazide diuretics in patients with essential hypertension]. ( Semenkin, AA, 2007) |
| "Perindopril/indapamide treatment reduced 24-hour and daytime systolic BP (SBP) and pulse pressure (PP) significantly more than enalapril treatment (p < 0." | 2.73 | Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy. ( Asmar, R; De Leeuws, PW; Garcia-Puig, J; Gosse, P; Karpov, YA; Magometschniggs, D; Matos, L; Schmieder, R, 2007) |
| "Thus, in patients with type 2 diabetes, a drug regimen based on a fixed-dose combination of perindopril/ indapamide affords major protection against both the macro and microvascular complications." | 2.73 | [ADVANCE: a morbidity mortality study of diabetes and hypertension]. ( Feihl, F; Heim, A; Waeber, B, 2008) |
| " Once daily dosing of the preparation provided high level of compliance of patients with treatment." | 2.72 | [Effect of twelve-month combined therapy with perindopril and indapamide on the level of blood pressure and left ventricular hypertrophy in patients with hypertensive disease]. ( Alekhin, MN; Chumakova, OS; Larina, VN; Sidorenko, BA; Timofeeva, LA; Ugriumov, MO, 2006) |
| "625 mg with reductions in mean 24-h blood pressure from 24-48 h and 48-72 h after dosing being -11." | 2.72 | Persistence of the antihypertensive effect of low-dose combination therapy in mild hypertension. ( Leenen, FH; Myers, MG, 2006) |
| "Patients with type 2 diabetes mellitus have markedly increased risks of developing vascular diseases." | 2.71 | [ADVANCE study: objectives, design and current status]. ( Chalmers, J, 2003) |
| "Perindopril/indapamide treatment led already after 4 weeks to a significant blood (BP) reduction with most prominent BP differences at the end of the study (sitting BP 130 +/- 10/84 +/- 6 mm Hg vs." | 2.71 | [Evaluation of the antihypertensive efficacy and tolerability of fixed very low-dose perindopril/indapamid combination in patients with mild to moderate hypertension. Results of a Czech and Slovak multicentric study]. ( Fedelesová, V; Widimský, J, 2004) |
| "Indapamide is an antihypertensive agent similar to thiazides, but with some different effects." | 2.71 | Effect of indapamide on urinary calcium excretion in patients with and without urinary stone disease. ( Algun, E; Can, S; Ceylan, K; Dogan, E; Erkoc, R; Gonulalan, H; Sayarlioglu, H; Topal, C; Yilmaz, Y, 2005) |
| "Indapamide (1 mg) was added to their existing treatment once daily for 4 weeks." | 2.71 | Efficacy of combination antihypertensive therapy with low-dose indapamide: assessment by blood pressure self-monitoring at home. ( Asayama, K; Hanasawa, T; Hashimoto, J; Hirayama, H; Imai, Y; Kikuya, M; Metoki, H; Ohkubo, T; Totsune, K; Watabe, D, 2005) |
| "In the overall population, there was a significant dose-response relationship (P < 0." | 2.70 | Gender influence on the dose-ranging of a low-dose perindopril-indapamide combination in hypertension: effect on systolic and pulse pressure. ( Asmar, R; Leenen, F; Myers, MG; Safar, ME, 2002) |
| "The PICXEL study is designed to evaluate the effects of long-term administration of very low-dose combination perindopril 2 mg/indapamide 0." | 2.70 | Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design. ( Amouyel, P; Asmar, R; Dahlöf, B; De Leeuw, PW; De Simone, G; Degaute, JP; Dubourg, O; García Puig, J; Gosse, P; Guéret, P; Karpov, Y; Le Heuzey, JY; Magometschnigg, D; Matos, L; Nieminen, M; Schmieder, R, 2002) |
| "CARDIOVASCULAR RISK OF LEFT VENTRICULAR HYPERTROPHY: Because of the rhythmic, mechanical and ischemic risk related to it, the left ventricular hypertrophy (LVH) is considered to be a major independent risk factor for cardiovascular disease which should be screened for and treated early." | 2.70 | [Management of hypertensive patients with left ventricular hypertrophy]. ( Ambrosioni, E, 2002) |
| "625 mg indapamide once a day or every other day, with the possibility of dosage adjustment to perindopril 4 mg/indapamide 1." | 2.69 | Fixed low-dose perindopril-indapamide combination in hypertensive patients with chronic renal failure. ( Dratwa, M; Lachaud-Pettiti, V; Meyrier, A; Sennesael, J, 1998) |
| "5) of indapamide, a diuretic related to thiazide, has been pointed out by using conventional sphygmomanometric measurement 24 h after dosing in clinic, in two large European randomized, double-blind, controlled studies (2 and 3 months)." | 2.69 | Twenty-four hour antihypertensive efficacy of indapamide, 1.5-mg sustained release: results of two randomized double-blind controlled studies. ( Asmar, R; Boutelant, S; Guez, D; Mallion, JM, 1998) |
| " After a 2-week placebo run-in, patients took 30 mg delapril in combination with 1." | 2.69 | Effects of delapril in combination with indapamide on blood pressure and left ventricular mass in elderly hypertensive patients. ( Acanfora, D; Furgi, G; Iannuzzi, GL; Lowenthal, DT; Nicolino, A; Papa, A; Picone, C; Rengo, F; Trojano, L, 1998) |
| " Adverse event rates (including hypokalemia) were similarly low in both groups." | 2.69 | Efficacy and safety of an oral fixed low-dose perindopril 2 MG/indapamide 0.625 MG combination: a randomized, double-blind, placebo-controlled study in elderly patients with mild to moderate hypertension. ( Castaigne, A; Chalmers, J; Chastang, C; Feldmann, L; Guez, D; Morgan, T, 1999) |
| "Treatment with indapamide 1." | 2.68 | Conversion from 2.5 mg to 1.25 mg indapamide in patients with mild to moderate hypertension. ( Boyd, G; Chrysant, S; Codispoti, J; Dawson, J; Gardner, T; Hill, G; Lee, W; Levine, B; Stokes, A; Vergis, J, 1995) |
| "Indapamide is a diuretic and vasodilator that does not raise blood glucose or lipid levels." | 2.68 | [Indapamide--a substitute diuretic for hypertensives with hyperglycemia and/or dyslipidemia]. ( Grossman, E; Katz, A; Nussinovitch, N; Rachima-Moaz, C; Rosenthal, T; Sharabi, Y, 1996) |
| "Indapamide 1." | 2.68 | Evaluation of indapamide 1.25 mg once daily in elderly patients with mild to moderate hypertension. ( Blumenthal, J; Codispoti, J; Dawson, JE; Dyckman, E; Fiddes, R; Harris, S; Lasseter, KC; Levine, BS; Montoro, R; Niederman, AL; Ratner, PH; Rosenblatt, S; St John Hammond, PG; Toth, PD; Vergis, J, 1997) |
| "Indapamide is an antihypertensive drug suitable for treatment of mild hypertension in diabetics as monotherapy." | 2.67 | [Indapamide in the treatment of hypertension in diabetes]. ( Klabusay, L; Olsovský, J; Podrouzková, B, 1992) |
| "Indapamide is a new, nonthiazide diuretic and vasodilator." | 2.67 | Regression of left ventricular hypertrophy in hypertension with indapamide. ( Haichin, R; Sami, M, 1991) |
| " To the above therapy was therefore associated a low dosage diuretic (indapamide 2." | 2.67 | [Antihypertensive treatment: a combination of delapril, a new ACE-inhibitor, and indapamide]. ( Alberici, M; Coruzzi, P; Novarini, A; Ravanetti, C, 1990) |
| " After a 2-week single-blind placebo run-in period, patients received indapamide either alone (group I) or in combination with the previous therapy (groups II and III) for 4 months." | 2.67 | Clinical efficacy and quality of life with indapamide alone or in combination with beta blockers or angiotensin-converting enzyme inhibitors. ( Athanassiadis, DI; Boutin, B; Cokkinos, DF; Dimopoulos, CG; Guez, D; Tourkantonis, AA; Toutouzas, PK; Tsakiris, AK, 1990) |
| "Since hypertension is an important risk factor of cardiovascular morbidity and mortality that can be at least in part decreased by pharmacologic reduction in elevated blood pressure, it is necessary that an antihypertensive agent be effective, but at the same time well tolerated and, according to some recent hypotheses, have no deleterious effect on serum electrolyte levels, as well as lipoprotein and glucose tolerance." | 2.66 | Tolerability and well-being with indapamide in the treatment of mild-moderate hypertension. An Italian multicenter study. ( Leonetti, G; Rappelli, A; Salvetti, A; Scapellato, L, 1988) |
| "Indapamide was prescribed to replace hydrochlorothiazide, the other antihypertensive drugs being continued in those patients receiving combination therapy." | 2.65 | The treatment of hypertension with indapamide alone or in combination with other drugs. ( L'Homme, C; Lemieux, G, 1983) |
| "Indapamide is a useful antihypertensive agent with good patient tolerance in mild or moderate hypertension and may offer advantages over traditional diuretics in view of its possible vasodilator and calcium-antagonist properties, once-a-day dosage, and good therapeutic effect with prolonged usage." | 2.65 | Clinical efficacy and safety of indapamide in essential hypertension. ( Morledge, JH, 1983) |
| " The results obtained from single-blind, placebo-controlled studies indicate that indapamide is a safe and effective agent to use in lowering the blood pressure of hypertensive patients with normal renal function, those with various degrees of renal impairment, and those who are undergoing long-term maintenance hemodialysis." | 2.65 | Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment. ( Acchiardo, SR; Skoutakis, VA, 1983) |
| "Indapamide has been the subject of a long-term safety study in which over 100 hypertensive patients have been followed up for 2 years or longer." | 2.65 | Multi-centre clinical investigation of indapamide in the United States: a review. ( Barton, J; Bronstein, R; Caruso, F; Eff, J; Losi, M; Neiss, ES; Schotz, WE; Vukovich, RA; Webb, E; Zisblatt, M, 1983) |
| " It is concluded that indapamide and pindolol at the dosage levels used are drugs of comparable antihypertensive activity." | 2.65 | Indapamide versus beta-blocker therapy: a double-blind, crossover study in essential hypertension. ( Jurisic, M; Rumboldt, M; Rumboldt, Z, 1984) |
| " All groups had mean diastolic pressure controlled at or below the 90 mmHg criterion during the period of constant methyldopa dosage for those patients who required Step 2 therapy." | 2.65 | Indapamide in the stepped-care treatment of obese hypertensive patients. ( Godfrey, JC; Neiss, ES; Noble, RE; Vukovich, RA; Webb, EL; Zisblatt, M, 1983) |
| "Perindopril/indapamide treatment has been shown to reduce blood pressure and to have significant beneficial effects on arterial distensibility, kidney structure and function, and endothelial function." | 2.58 | Vascular legacy beyond blood pressure control: benefits of perindopril/indapamide combination in hypertensive patients with diabetes. ( Lévy, BI; Taddei, S, 2018) |
| "Hydrochlorothiazide has less effect on blood pressure, a high risk of metabolic side effects, and may not have pleiotropic effects." | 2.55 | [All diuretics used in the treatment of hypertension are not the same]. ( Asil, S; Atalar, E, 2017) |
| "Hypertension is a powerful risk factor strongly linked to adverse cardiovascular outcomes." | 2.52 | Misconceptions and facts about treating hypertension. ( Argulian, E; Grossman, E; Messerli, FH, 2015) |
| "Hydrochlorothiazide (HCTZ) has often been contrasted with chlorthalidone, but relatively little is known about HCTZ versus indapamide (INDAP)." | 2.52 | Head-to-head comparisons of hydrochlorothiazide with indapamide and chlorthalidone: antihypertensive and metabolic effects. ( Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Tandon, S, 2015) |
| " The results can be related to gradually weakening protective effect of perindopril/indapamide combination on cardiovascular system, and are indicative of the expedience of long-term use of this antihypertensive therapy for maximal lowering of mortality of patients with diabetes." | 2.52 | [ADVANCE-ON Trial; How to Achieve Maximum Reduction of Mortality in Patients With Type 2 Diabetes]. ( Kanorskiĭ, SG, 2015) |
| "Hypertension is a modifiable cardiovascular risk factor." | 2.50 | Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension. ( Bassett, K; Musini, VM; Nazer, M; Wright, JM, 2014) |
| "Indapamide, because of its well-documented beneficial effects on cardiovascular and renal outcomes, represents a safe and valuable option for treating patients with high BP." | 2.48 | Position of indapamide, a diuretic with vasorelaxant activities, in antihypertensive therapy. ( Feihl, F; Rotaru, C; Waeber, B, 2012) |
| "Hypertension is an important risk factor for cardiovascular complications and the need to treat this condition has been well established." | 2.47 | Combination perindopril/indapamide for the treatment of hypertension: a review. ( de Leeuw, PW, 2011) |
| "Pharmacological treatment of hypertension represents a cost-effective way for preventing cardiovascular and renal complications." | 2.44 | The need for combination antihypertensive therapy to reach target blood pressures: what has been learned from clinical practice and morbidity-mortality trials? ( Ambrosioni, E; Holzgreve, H; Laurent, S; Mancia, G; Ruilope, LM; Struijker-Boudier, HA; Waeber, B, 2007) |
| " The trials selected were published between 1973 and 2004, evaluated monotherapy with trial drugs as fixed-dosage or with dosage increase, and assessed blood pressure reduction between 2 and 3 months." | 2.43 | A meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure. ( Auquier, P; Baguet, JP; Boyer, L; Debensason, D; Robitail, S, 2005) |
| "Hypertension is the most significant risk factor for stroke." | 2.43 | [Management of hypertension in elderly patients with stroke]. ( Bokura, H; Kobayashi, S, 2005) |
| "Indapamide SR was also more effective than enalapril in reducing left ventricular hypertrophy (LVH), and similar reductions in renal end-organ damage, assessed by microalbuminuria, were seen with indapamide SR- and enalapril-based antihypertensive strategies." | 2.43 | Indapamide sustained release: a review of its use in the treatment of hypertension. ( Robinson, DM; Wellington, K, 2006) |
| " The fixed dosage of a once-daily tablet, ensures optimal ease of use and enhances patient compliance." | 2.43 | Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection. ( Gosse, P, 2006) |
| "Pharmacological treatment of hypertension represents a cost-effective way of preventing cardiovascular and renal complications." | 2.43 | Managing hypertension in high-risk patients: lessons and promises from the STRATHE and ADVANCE trials. ( Waeber, B, 2006) |
| "Hypertension is a major influence on the development of LVH." | 2.43 | Ventricular hypertrophy and hypertension: prognostic elements and implications for management. ( Devereux, RB; Krauser, DG, 2006) |
| " Diuretics used at lower dosage than in the past are effective in reducing morbidity and mortality and continue to be drugs of first choice in the treatment of hypertension." | 2.42 | Clinical role of Natrilix SR in the treatment of at-risk hypertensive patients. ( Ambrosioni, E; Veronesi, M, 2003) |
| "Essential hypertension is a very heterogeneous disease and different pressor mechanisms might interact to increase blood pressure." | 2.42 | Very-low-dose combination: a first-line choice for the treatment of hypertension? ( Waeber, B, 2003) |
| "The treatment with indapamide SR resulted in a better or equivalent control of SBP than treatment with a standard dose of a true thiazide diuretic (hydrochlorothiazide), a calcium channel blocker (amlodipine), and an angiotensin-converting enzyme inhibitor (enalapril)." | 2.42 | Efficacy of indapamide 1.5 mg, sustained release, in the lowering of systolic blood pressure. ( London, GM, 2004) |
| "Indapamide SR 1." | 2.41 | Metabolic profile of indapamide sustained-release in patients with hypertension: data from three randomised double-blind studies. ( Weidmann, P, 2001) |
| "Hyperlipidemia is a widely acknowledged side effect of thiazide diuretic therapy, but it is often dismissed as a short-term effect of high-dose therapy." | 2.40 | Hyperlipidemia of diuretic therapy. ( Ames, R, 1998) |
| "Indapamide is a thiazide-related diuretic drug with antihypertensive properties." | 2.40 | Pharmacological properties of indapamide. Rationale for use in hypertension. ( Bataillard, A; Sassard, J; Schiavi, P, 1999) |
| "Indapamide SR 1." | 2.40 | Clinical implications of indapamide sustained release 1.5 mg in hypertension. ( Donnelly, R, 1999) |
| " The recently developed sustained release (SR) formulation of indapamide allows use of a lower daily dosage of the drug, thereby improving its efficacy:safety ratio in comparison with immediate release formulations." | 2.40 | Concluding remarks. Pursuit of the optimal outcome in hypertension. ( Hansson, L, 1999) |
| "Indapamide SR has also been shown to be effective (more than 20 mg enalapril) in the reduction of left ventricular mass index (LVMI) in hypertensive patients treated for one year (LIVE study)." | 2.40 | [Renaissance of diuretics in the treatment of hypertension]. ( Hörl, WH, 1999) |
| "Thiazide diuretics in high dosage adversely affect the lipid profile." | 2.39 | A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides. ( Ames, RP, 1996) |
| "Left ventricular hypertrophy is a major risk factor for cardiovascular morbidity and mortality." | 2.39 | Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis. ( Carey, PA; de Cordoue, A; Guez, D; Sheridan, DJ, 1996) |
| "Spironolactone has a lesser effect on lipids than do thiazides." | 2.37 | Effects of diuretic drugs on the lipid profile. ( Ames, R, 1988) |
| "Indapamide does not increase magnesium excretion when given in single doses to normal volunteers." | 2.36 | Indapamide: a review. ( Leary, WP; Reyes, AJ, 1983) |
| "Diuretics are commonly used for the treatment of hypertension." | 1.91 | Incidence of severe hypokalaemia in patients taking indapamide. ( Cheung, BMY; Lin, Z; Tang, V; Tsoi, MF, 2023) |
| "Arterial hypertension is the most prevalent risk factor for stroke." | 1.72 | Hypertension and dyslipidemia treament in stroke. ( Nussbaumerová, B, 2022) |
| " These findings may apply to drugs administered as a single dosage form or in separate dosage forms and hence need to be well controlled to assure effective treatments and patient safety." | 1.56 | Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs. ( Alhalaweh, A; Bergström, CAS; El Sayed, M, 2020) |
| " The primary objective of the PETRA study was to evaluate the efficacy of blood pressure (BP) control with once daily administration of the different dosage strengths of the once-daily, triple fixed combination of perindopril, indapamide, and amlodipine." | 1.46 | The Antihypertensive Efficacy of the Triple Fixed Combination of Perindopril, Indapamide, and Amlodipine: The Results of the PETRA Study. ( Ábrahám, G; Dézsi, CA, 2017) |
| "Treatment with amlodipine, candesartan, or indapamide did not significantly affect plasma visfatin levels." | 1.43 | Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations. ( Piecha, G; Skoczylas, A; Więcek, A, 2016) |
| "Determination of the effectiveness and safety of different dosing regimens during the day (in the morning or at bedtime) combination therapy including azilsartan medoxomil in patients with essential hypertension and metabolic syndrome (MS)." | 1.43 | [Hronotherapy Aspects of Efficiency Azilsartan Medoxomil in Combination Therapy in Patients With Hypertension and Metabolic Syndrome]. ( Fendrikova, AV; Sirotenko, DV; Skibitskiy, AV; Skibitskiy, VV, 2016) |
| "Hypertension and type 2 diabetes mellitus (T2DM) synergistically deteriorate the vascular environment, making blood pressure reduction challenging, and substantially increasing cardiovascular risk." | 1.40 | Efficacy and tolerability of fixed-dose combination of perindopril/indapamide in type 2 diabetes mellitus: PICASSO trial. ( Farsang, C, 2014) |
| "Perindopril/indapamide was well tolerated with no significant changes in laboratory parameters being observed." | 1.37 | Efficacy and safety of treatment of hypertensive patients with fixed combination perindopril/indapamide up to 10/2.5 mg: results of the FALCO FORTE programme. ( Pella, D, 2011) |
| "Guidelines for the treatment of hypertension recommend reducing blood pressure to below 140/90 mmHg." | 1.33 | [Comparison of therapeutic strategies in the management of hypertension]. ( Waeber, B, 2005) |
| "In hypertensive patients with Type 2 diabetes, a greater reduction of urinary albumin excretion can be obtained with the perindopril/indapamide association compared with an angiotensin-converting enzyme inhibitor administered as monotherapy." | 1.33 | What can be learned from the experience with the fixed low-dose combination of perindopril/indapamide in the treatment of hypertension? ( Waeber, B, 2005) |
| "Indapamide is a well known blocker of the slow component of the delayed rectifier current leading to prolongation of cardiac repolarization." | 1.33 | QT interval prolongation and torsade de pointes associated with indapamide. ( Alexanian, IP; Efremidis, M; Kardaras, F; Kounas, SP; Letsas, KP; Pappas, LK; Sideris, A, 2006) |
| "Factors that must be considered for the treatment of hypertension in patients, particularly with type 2 diabetes." | 1.31 | [Reflexion of French experts on the key points of the symposium]. ( Dubourg, O; Forette, F; Hanon, O; Mallion, JM; Marre, M, 2002) |
| "Indapamide was immediately stopped, but the QT remained prolonged 2 days later, although the potassium level was normalized." | 1.31 | Indapamide induced syncope in a patient with long QT syndrome. ( Guo, GB; Wang, CP, 2002) |
| "Treatment with indapamide alone at this dosage did not significantly influence most responses but in combination with perindopril it strengthened the effect of perindopril." | 1.31 | The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats. ( Cicutti, N; Guez, D; Maurin, A; Rakusan, K; Schiavi, P, 2000) |
| "5 mg/kg/day) combined with indapamide (0." | 1.31 | Protective effects of delapril combined with indapamide or hydrochlorothiazide in spontaneously hypertensive stroke-prone rats: a comparative dose-response analysis. ( Agnati, LF; Biagini, G; Boschi, S; Torri, C; Vantaggiato, G; Zini, I; Zoli, M, 2000) |
| " Dose-response curves were repeated after local tetraethylammonium (TEA) administration to determine the role of potassium channel activation and, in patients with the Gitelman syndrome, to determine the role of the thiazide-sensitive Na-Cl cotransporter in the vasodilator effect of hydrochlorothiazide." | 1.30 | Thiazide-induced vasodilation in humans is mediated by potassium channel activation. ( Hughes, AD; Pickkers, P; Russel, FG; Smits, P; Thien, T, 1998) |
| "A sprightly 79-year-old woman was treated for high blood pressure with indapamide (2." | 1.29 | [Severe pancytopenia in old age after 12-month ACE inhibitor therapy]. ( Antoni, D; Delius, W; Lipp, T; Riess, G; Schratzlseer, G, 1994) |
| "Indapamide treatment increased carotid arterial static compliance in Dahl salt-sensitive rats with a high or low NaCl diet and to a lesser extent in Dahl salt-resistant rats." | 1.29 | Carotid artery mechanical properties of Dahl salt-sensitive rats. ( Albaladejo, P; Benetos, A; Bouaziz, H; Guez, D; Safar, ME, 1995) |
| " The results of our clinical trial showed that metipamide is an effective first-line antihypertensive agent, in that it combines satisfactory reduction of blood pressure with a low frequency of side-effects and a simple once-daily dosage regime." | 1.28 | Therapeutic monitoring of metipamide during antihypertensive therapy. ( Grafnetterová, J; Klíma, J; Kubelka, Z, 1989) |
| "Treatment with indapamide has comparable results on both young and elderly." | 1.27 | Once daily indapamide in the treatment of the elderly and young hypertensive. ( Glover, DR; Littler, WA; Rowlands, DB; Stallard, TJ; Young, MA, 1984) |
| "Indapamide is an orally active sulphonamide diuretic agent." | 1.27 | Indapamide. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. ( Avery, GS; Brogden, RN; Chaffman, M; Heel, RC; Speight, TM, 1984) |
| " It is therefore concluded that continuous control of water intake and analysis of the stability of the drug is essential for the establishment of proper dose-response relationships." | 1.27 | Drinking water and drug dosage in rat studies. ( Jakobsen, P; Jespersen, LT; Mikkelsen, EO; Pedersen, OL, 1983) |
| " There is growing experimental and clinical evidence that indapamide, an antihypertensive agent with only limited diuretic activity at low dosage (2." | 1.27 | The place of indapamide in the treatment of arterial hypertension. ( Thénot, A, 1983) |
| "Indapamide (Lozol) is a new diuretic and antihypertensive agent." | 1.27 | Indapamide: a unique diuretic? ( Conner, CS, 1983) |
| "Renal hypertrophy was also decreased significantly by cicletanine at a dose of 100 mg/kg." | 1.27 | Comparison of cicletanine with other antihypertensive drugs in SHR-SP models. ( Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E, 1988) |
| "Indapamide is a nonthiazide antihypertensive agent that appears to respect the glucose tolerance in hypertensive patients." | 1.27 | Antihypertensive therapy in diabetic patients. The use of indapamide. ( Harrower, AD; McFarlane, G, 1988) |
| "Indapamide was well absorbed in every patient (mean plasma level at the steady state was 111 +/- 41 ng/ml) and its antihypertensive action was more pronounced in hypertensive than in normotensive patients." | 1.27 | Acute effect of indapamide on urine calcium excretion in nephrolithiasis and human essential hypertension. ( Amato, F; Barbarese, F; Borghi, L; Elia, G; Melloni, E; Novarini, A; Trapassi, MR, 1988) |
| "Indapamide has been well tolerated by all patients." | 1.26 | [Ambulatory treatment of hypertension]. ( Henrich, H; Kababgi, MD; Schneider, KW, 1980) |
| "Indapamide has a prolonged saluretic action which in combination with the direct vascular effects may well account for its antihypertensive activity." | 1.25 | Antihypertensive action of indapamide. Comparative studies in several experimental models. ( Kyncl, J; Oheim, K; Seki, T; Solles, A, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 153 (23.91) | 18.7374 |
| 1990's | 94 (14.69) | 18.2507 |
| 2000's | 227 (35.47) | 29.6817 |
| 2010's | 133 (20.78) | 24.3611 |
| 2020's | 33 (5.16) | 2.80 |
| Authors | Studies |
|---|---|
| Chow, CK | 3 |
| Atkins, ER | 3 |
| Hillis, GS | 3 |
| Nelson, MR | 1 |
| Reid, CM | 2 |
| Schlaich, MP | 1 |
| Hay, P | 2 |
| Rogers, K | 1 |
| Billot, L | 5 |
| Burke, M | 1 |
| Chalmers, J | 31 |
| Neal, B | 16 |
| Patel, A | 18 |
| Usherwood, T | 2 |
| Webster, R | 2 |
| Rodgers, A | 9 |
| Opolskaya, SV | 2 |
| Skibitsky, VV | 2 |
| Fendrikova, AV | 5 |
| Zabolotskich, TB | 1 |
| Skibitsky, AV | 1 |
| Ostroumova, OD | 7 |
| Polyakova, OA | 1 |
| Listratova, AI | 1 |
| Logunova, NA | 1 |
| Gorohova, TV | 1 |
| Kobalava, ZD | 3 |
| Kolesnik, EL | 1 |
| Shavarova, EK | 1 |
| Goreva, LA | 1 |
| Karapetyan, LV | 1 |
| Syed, YY | 1 |
| Habboush, S | 1 |
| Sofy, AA | 1 |
| Masoud, AT | 1 |
| Cherfaoui, O | 1 |
| Farhat, AM | 1 |
| Abdelsattar, AT | 1 |
| Elmoursi, A | 1 |
| Ernst, ME | 4 |
| Fravel, MA | 1 |
| Mbanya, A | 1 |
| Ackbarkhan, A | 1 |
| Mittoo, MY | 1 |
| Ramamonjisoa, HA | 1 |
| Ramilitiana, B | 1 |
| Ranivoharisoa, EM | 1 |
| Ratsimbazafy, SJN | 1 |
| Mbanya, JC | 2 |
| Nussbaumerová, B | 1 |
| Podzolkov, VI | 2 |
| Bragina, AЕ | 1 |
| Rodionova, YN | 1 |
| Bragina, GI | 1 |
| Bykova, EE | 1 |
| Mourad, JJ | 10 |
| Brzozowska-Villatte, R | 3 |
| De Champvallins, M | 4 |
| Mancia, G | 15 |
| Lin, Z | 1 |
| Cheung, BMY | 1 |
| Tang, V | 1 |
| Tsoi, MF | 1 |
| Šukalo, A | 1 |
| Džananović Jaganjac, J | 1 |
| Tanović Avdić, A | 1 |
| Glamočlija, U | 1 |
| Popović, Ž | 1 |
| Boloban, A | 1 |
| Tirić Čampara, M | 1 |
| Mehić, M | 1 |
| Borghi, C | 3 |
| Jayagopal, PB | 2 |
| Konradi, A | 1 |
| Bortolotto, LA | 2 |
| Degli Esposti, L | 2 |
| Perrone, V | 2 |
| Snyman, JR | 2 |
| Konradi, AO | 1 |
| Peces, R | 1 |
| Peces, C | 1 |
| Espinosa, L | 1 |
| Mena, R | 1 |
| Blanco, C | 1 |
| Tenorio-Castaño, J | 1 |
| Lapunzina, P | 1 |
| Nevado, J | 1 |
| McNally, RJ | 1 |
| Morselli, F | 1 |
| Farukh, B | 1 |
| Chowienczyk, PJ | 1 |
| Faconti, L | 1 |
| Kalra, S | 1 |
| Sosale, A | 1 |
| Shah, SN | 1 |
| Jabre, G | 1 |
| Joseph, S | 2 |
| Rajarshi, M | 2 |
| Lee, AK | 1 |
| Woodward, M | 20 |
| Wang, D | 2 |
| Ohkuma, T | 1 |
| Warren, B | 1 |
| Sharrett, AR | 1 |
| Williams, B | 13 |
| Marre, M | 14 |
| Hamet, P | 12 |
| Harrap, S | 13 |
| Mcevoy, JW | 2 |
| Selvin, E | 2 |
| Mazza, A | 2 |
| Townsend, DM | 1 |
| Schiavon, L | 2 |
| Torin, G | 1 |
| Lenti, S | 2 |
| Rossetti, C | 1 |
| Rigatelli, G | 2 |
| Rubello, D | 1 |
| Knudsen, ST | 1 |
| Cooper, ME | 4 |
| Argyris, AA | 1 |
| Samara, S | 1 |
| Protogerou, AD | 1 |
| Skibitskiy, VV | 3 |
| Gutova, SR | 1 |
| Skibitskiy, AV | 2 |
| Mareev, VY | 1 |
| Minina, YV | 1 |
| Begrambekova, YL | 1 |
| Levin, AM | 1 |
| Nakagawa, N | 1 |
| Sato, N | 1 |
| Saijo, Y | 1 |
| Morimoto, H | 1 |
| Koyama, S | 1 |
| Ogawa, Y | 1 |
| Uekita, K | 1 |
| Maruyama, J | 1 |
| Ohta, T | 1 |
| Nakamura, Y | 1 |
| Takeuchi, T | 1 |
| Hasebe, N | 1 |
| El Sayed, M | 1 |
| Alhalaweh, A | 1 |
| Bergström, CAS | 1 |
| Jaruseviciene, R | 1 |
| Sirvydyte, G | 1 |
| Thacker, H | 1 |
| Konda Reddy, KM | 1 |
| Murthy, LS | 1 |
| Sawhney, JP | 1 |
| Chaudhary, G | 1 |
| Shah, S | 1 |
| Nikam, P | 1 |
| Nelson, M | 1 |
| Schlaich, M | 1 |
| Ostroumova, TM | 2 |
| Parfenov, VA | 1 |
| Perepelova, EM | 1 |
| Perepelov, VA | 1 |
| Kochetkov, AI | 2 |
| Dézsi, CA | 5 |
| Glezer, M | 2 |
| Karpov, Y | 5 |
| Farsang, C | 5 |
| Petrova, MM | 1 |
| Moskaleva, PV | 1 |
| Shnayder, NA | 1 |
| Nasyrova, RF | 1 |
| Rosolová, H | 1 |
| Wang, N | 2 |
| Harris, K | 1 |
| Poulter, N | 12 |
| Tzourio, C | 2 |
| Zoungas, S | 8 |
| Trujillo, H | 1 |
| Caravaca-Fontán, F | 1 |
| Caro, J | 1 |
| Morales, E | 1 |
| Praga, M | 1 |
| Skrzypecki, J | 1 |
| Gawlak, M | 1 |
| Huc, T | 1 |
| Szulczyk, P | 1 |
| Ufnal, M | 1 |
| Liang, W | 1 |
| Ma, H | 1 |
| Cao, L | 1 |
| Yan, W | 1 |
| Yang, J | 1 |
| Ábrahám, G | 1 |
| Okamura, K | 1 |
| Shirai, K | 1 |
| Totake, N | 1 |
| Okuda, T | 1 |
| Urata, H | 1 |
| Wang, S | 1 |
| Li, J | 1 |
| Zhou, X | 1 |
| Liu, K | 1 |
| Zhang, X | 1 |
| Meng, Q | 1 |
| Shi, R | 1 |
| Shi, D | 1 |
| Chen, X | 1 |
| Hanon, O | 4 |
| Caillard, L | 2 |
| Chaussade, E | 2 |
| Hernandorena, I | 1 |
| Boully, C | 2 |
| Glezer On Behalf Of The Forsage Program Participants, MG | 1 |
| Kobalava, Z | 1 |
| Troitskaya, E | 1 |
| Ezhova, N | 1 |
| Kobalava, DZ | 1 |
| Shavarova, KE | 1 |
| Tkachyeva, ON | 1 |
| Kotovskaya, YV | 2 |
| Dudinskaya, EN | 1 |
| Lévy, BI | 8 |
| Taddei, S | 3 |
| Roush, GC | 3 |
| Abdelfattah, R | 2 |
| Song, S | 2 |
| Kostis, JB | 3 |
| Sica, DA | 3 |
| Phylactou, M | 1 |
| Matarazzo, F | 1 |
| Jones, E | 1 |
| Tadic, M | 1 |
| Cuspidi, C | 2 |
| Troitskaya, EA | 1 |
| Tolkacheva, VV | 1 |
| Macfarlane, TV | 1 |
| Pigazzani, F | 1 |
| Flynn, RWV | 1 |
| MacDonald, TM | 1 |
| Starodubova, AV | 2 |
| Cherniaeva, MS | 1 |
| Kuusela, PJ | 1 |
| Privalova, EV | 1 |
| Lishuta, AS | 1 |
| Elfimova, EM | 1 |
| Litvin, AY | 1 |
| Chazova, IE | 4 |
| Tsioufis, K | 1 |
| Douma, S | 1 |
| Kallistratos, MS | 1 |
| Manolis, AJ | 1 |
| Borisova, EV | 1 |
| Juraschek, SP | 1 |
| Lazo, M | 1 |
| van der Merwe, WM | 1 |
| Sobngwi, E | 1 |
| Mfeukeu-Kuate, L | 1 |
| Kouam, M | 1 |
| Tankeu, AT | 1 |
| Nganou-Gnindjio, CN | 1 |
| Hamadou, B | 1 |
| Etoa, M | 1 |
| Ngassam, E | 1 |
| Nkamgna, A | 1 |
| Dehayem, MY | 1 |
| Kaze, FF | 1 |
| Kengne, AP | 5 |
| Topouchian, J | 2 |
| Feldmann, L | 2 |
| Asmar, R | 18 |
| Karpov, IuA | 3 |
| Agnoletti, D | 3 |
| Zhang, Y | 4 |
| Blacher, J | 3 |
| Safar, ME | 20 |
| Peters, R | 16 |
| Beckett, N | 14 |
| Fagard, R | 5 |
| Thijs, L | 7 |
| Wang, JG | 4 |
| Forette, F | 7 |
| Pereira, L | 1 |
| Fletcher, A | 10 |
| Bulpitt, C | 12 |
| Püllen, R | 1 |
| Dovjak, P | 1 |
| Galiavich, AS | 2 |
| Galiavi, RA | 1 |
| Baleeva, LV | 1 |
| Arima, H | 4 |
| Hirakawa, Y | 3 |
| Yamout, H | 1 |
| Bakris, GL | 2 |
| Netchessova, TA | 1 |
| Shepelkevich, AP | 1 |
| Gorbat, TV | 1 |
| Blomster, JI | 1 |
| Li, Q | 2 |
| Tóth, K | 1 |
| Jadhav, U | 1 |
| Hiremath, J | 1 |
| Namjoshi, DJ | 1 |
| Gujral, VK | 1 |
| Tripathi, KK | 1 |
| Siraj, M | 1 |
| Shamanna, P | 1 |
| Safar, M | 8 |
| Gueyffier, F | 1 |
| Subtil, F | 1 |
| Bejan-Angoulvant, T | 1 |
| Zerbib, Y | 1 |
| Baguet, JP | 2 |
| Boivin, JM | 1 |
| Mercier, A | 1 |
| Leftheriotis, G | 1 |
| Gagnol, JP | 1 |
| Fauvel, JP | 1 |
| Giraud, C | 1 |
| Bricca, G | 1 |
| Maucort-Boulch, D | 1 |
| Erpeldinger, S | 1 |
| Holzgreve, H | 5 |
| Kakhramanova, SM | 1 |
| Bakhshaliev, AB | 1 |
| Musini, VM | 1 |
| Nazer, M | 1 |
| Bassett, K | 1 |
| Wright, JM | 1 |
| Tarlovskaia, EI | 2 |
| Balandina, IuA | 1 |
| Maksimchuk-Kolobova, NS | 1 |
| Leonetti, G | 7 |
| Duggan, J | 2 |
| Narkiewicz, K | 3 |
| McCormack, T | 3 |
| Banya, W | 4 |
| Kisliak, OA | 4 |
| Páll, D | 1 |
| Szántó, I | 1 |
| Szabó, Z | 1 |
| Monaghan, H | 1 |
| Joshi, R | 6 |
| Colagiuri, S | 2 |
| Glasziou, P | 5 |
| Grobbee, D | 3 |
| Heller, S | 4 |
| Lisheng, L | 2 |
| Matthews, DR | 1 |
| Mogensen, CE | 5 |
| Perkovic, V | 8 |
| MacMahon, S | 10 |
| Vinereanu, D | 1 |
| Dulgheru, R | 1 |
| Magda, S | 1 |
| Dragoi Galrinho, R | 1 |
| Florescu, M | 1 |
| Cinteza, M | 1 |
| Granger, C | 1 |
| Ciobanu, AO | 1 |
| Peng, J | 1 |
| Zhao, Y | 1 |
| Zhang, H | 1 |
| Liu, Z | 1 |
| Wang, Z | 2 |
| Tang, M | 1 |
| Zhong, M | 1 |
| Lu, F | 1 |
| Zhang, W | 1 |
| Amodeo, C | 1 |
| Gamba, MA | 1 |
| Puig, JG | 3 |
| Thomopoulos, C | 1 |
| Parati, G | 1 |
| Zanchetti, A | 2 |
| Argulian, E | 1 |
| Grossman, E | 2 |
| Messerli, FH | 1 |
| Xu, Y | 1 |
| Labourée, F | 1 |
| Cochiello, S | 1 |
| Kaplan, NM | 3 |
| Tandon, S | 1 |
| DiNicolantonio, JJ | 1 |
| Bhutani, J | 1 |
| Lavie, CJ | 1 |
| O'Keefe, JH | 1 |
| Scheen, AJ | 2 |
| Lancellotti, P | 1 |
| Krzesinski, JM | 3 |
| Warwick, J | 1 |
| Falaschetti, E | 1 |
| Rockwood, K | 2 |
| Mitnitski, A | 2 |
| Semenkin, AA | 3 |
| Zhenatov, AB | 1 |
| Zhivilova, LA | 2 |
| Nechaeva, GI | 2 |
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| Chindareva, OI | 1 |
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| Gilyarevskiy, SR | 1 |
| Nedogoda, SV | 8 |
| Chumachek, EV | 1 |
| Ledyaeva, AA | 1 |
| Tsoma, VV | 2 |
| Salasyuk, AS | 1 |
| Smirnova, VO | 1 |
| Hripaeva, VJ | 1 |
| Palashkin, RV | 1 |
| Pervichko, EI | 1 |
| Zinchenko, YP | 1 |
| Sirotenko, DV | 1 |
| Glezer, MG | 3 |
| Deev, AD | 2 |
| Gridina, SA | 1 |
| Povetkin, SV | 1 |
| Sacco, AP | 1 |
| Dell'Avvocata, F | 1 |
| Ramazzina, E | 1 |
| Ferguson, JM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925] | Phase 3 | 11,140 participants (Actual) | Interventional | 2001-06-30 | Completed | ||
| Short-term Effects of Perindopril-amlodipine Versus Perindopril-indapamide on Blood Pressure Control in Newly Diagnosed Type 2 Diabetes Individuals With Hypertension[NCT03747978] | Phase 4 | 30 participants (Actual) | Interventional | 2016-10-01 | Completed | ||
| IDEAL Study : Identification of the Determinants of the Efficacy of Arterial Blood Pressure Lowering Drugs[NCT00128518] | Phase 4 | 139 participants (Actual) | Interventional | 2004-10-31 | Completed | ||
| Action in Diabetes and Vascular Disease Preterax and Diamicron MR Controlled Evaluation Post Trial Observational Study[NCT00949286] | 8,494 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| The Hypertension in the Very Elderly Trial (HYVET)[NCT00122811] | Phase 4 | 4,000 participants (Anticipated) | Interventional | 2000-11-30 | Active, not recruiting | ||
| A Randomized, Open-label Study Investigating the Effect of Bilateral Renal Artery Sympathetic Denervation by Catheter-based Radiofrequency Ablation on Blood Pressure and Disease Progression in Autosomal Dominant Polycystic Kidney Disease[NCT01932450] | Phase 2 | 100 participants (Anticipated) | Interventional | 2013-08-31 | Recruiting | ||
| Pulse Wave Velocity as a Predictor for Postoperative Cardiovascular Events[NCT03223441] | 543 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| Essential Arterial Hypotension and Allostasis Registry[NCT02018497] | 5,000 participants (Anticipated) | Observational [Patient Registry] | 1995-01-31 | Recruiting | |||
| Estudio RioplateNsE Sobre Telemonitoreo en hIpertensos No-controlAdos[NCT02730052] | 0 participants (Actual) | Interventional | 2016-12-31 | Withdrawn (stopped due to Centers recruited poorly) | |||
| Morbidity and Mortality Based on Blood Pressure and Arterial Stiffness in Institutionalized Persons Aged 80 and Over: Study PARTAGE (Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population).[NCT00901355] | 1,130 participants (Actual) | Observational | 2007-01-31 | Completed | |||
| Acute Candesartan Cilexetil Outcomes Stroke Trial (ACCOST)[NCT00108706] | Phase 4 | 50 participants | Interventional | 2004-12-31 | Active, not recruiting | ||
| Longitudinal Change of Arterial Stiffness Indices in Relation to Ambulatory Aortic and Branchial Pressure in Long Term Peritoneal Dialysis Patients[NCT03607747] | 40 participants (Anticipated) | Observational | 2018-07-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
84 reviews available for indapamide and Hypertension
| Article | Year |
|---|---|
Thiazide and thiazide-like diuretics: how to make the right choice?
Topics: Antihypertensive Agents; Diuretics; Humans; Hypertension; Indapamide; Thiazides | 2022 |
Perindopril/Indapamide/Amlodipine in Hypertension: A Profile of Its Use.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Indapa | 2022 |
Efficacy of Single-Pill, Triple Antihypertensive Therapy in Patients with Uncontrolled Hypertension: A Systematic Review and Meta-analysis.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; D | 2022 |
Thiazide and the Thiazide-Like Diuretics: Review of Hydrochlorothiazide, Chlorthalidone, and Indapamide.
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indap | 2022 |
Benefit of treatment based on indapamide mostly combined with perindopril on mortality and cardiovascular outcomes: a pooled analysis of four trials.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Indapamide; | 2023 |
A review of the prescribing trend of thiazide-type and thiazide-like diuretics in hypertension: A UK perspective.
Topics: Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Drug Prescriptions; Drug Utilization; | 2019 |
Renal protection: What have we learnt from ADVANCE about kidney disease in type 2 diabetes?
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Humans; Hypertension; Hypoglycemic Agents; Indap | 2020 |
Beneficial Effects of a Perindopril/Indapamide Single-Pill Combination in Hypertensive Patients with Diabetes and/or Obesity or Metabolic Syndrome: A Post Hoc Pooled Analysis of Four Observational Studies.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Drug Combinations; Humans; | 2021 |
The Forgotten Antiproteinuric Properties of Diuretics.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Chlorthalidone; | 2021 |
Comparison of thiazide-like diuretics versus thiazide-type diuretics: a meta-analysis.
Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Chlorthalidone; Cholesterol; Diuretics; Huma | 2017 |
[Fixed-Drug Combination Amlodipine, Indapamide and Perindopril: New Horizons of Antihypertensive Therapy].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; D | 2017 |
[Clinical Features of Arterial Hypertension in the Elderly and Senile Age and the Rationale for Using the Combination of Amlodipine/Indapamide-retard].
Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Ther | 2017 |
Vascular legacy beyond blood pressure control: benefits of perindopril/indapamide combination in hypertensive patients with diabetes.
Topics: Antihypertensive Agents; Blood Circulation; Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hy | 2018 |
Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Diuretics, Potassium Spari | 2018 |
Hydrochlorothiazide vs chlorthalidone, indapamide, and potassium-sparing/hydrochlorothiazide diuretics for reducing left ventricular hypertrophy: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics, Potassium Sparing; Drug Therapy, | 2018 |
The effect of indapamide vs. bendroflumethiazide for primary hypertension: a systematic review.
Topics: Bendroflumethiazide; Blood Pressure; Coronary Artery Disease; Diuretics; Humans; Hypertension; Indap | 2019 |
Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Essential Hypertension; Humans; Hydr | 2014 |
Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2015 |
Misconceptions and facts about treating hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; | 2015 |
Head-to-head comparisons of hydrochlorothiazide with indapamide and chlorthalidone: antihypertensive and metabolic effects.
Topics: Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; I | 2015 |
Evidence-based diuretics: focus on chlorthalidone and indapamide.
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indap | 2015 |
[ADVANCE-ON Trial; How to Achieve Maximum Reduction of Mortality in Patients With Type 2 Diabetes].
Topics: Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Huma | 2015 |
The Results of ACES (Antihypertensive Combinations' Long Term Efficacy Comparing Study): Analysis of Metabolic Effects of Antihypertensive Combination Therapies.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel | 2016 |
[All diuretics used in the treatment of hypertension are not the same].
Topics: Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indapamide | 2017 |
[The Role of the Three-Drug Combination Antihypertensive in Improving the Treatment of Arterial Hypertension].
Topics: Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Humans; Hypertension; Indapamide; Pe | 2017 |
[Innovations in ambulatory care].
Topics: Acute Disease; Age Factors; Aged, 80 and over; Algorithms; Ambulatory Care; Analgesics; Angiotensin- | 2009 |
Implications of the ADVANCE study for clinical practice.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypertension; | 2008 |
Efficacy and safety of fixed combination of perindopril and indapamide in type 2 diabetes: results from ADVANCE in context of available evidence.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Evidence-Based Medici | 2008 |
Evaluation of high dose of perindopril/indapamide fixed combination in reducing blood pressure and improving end-organ protection in hypertensive patients.
Topics: Antihypertensive Agents; Blood Pressure; Cytoprotection; Dose-Response Relationship, Drug; Drug Comb | 2009 |
Blood pressure reduction for the secondary prevention of stroke: a Chinese trial and a systematic review of the literature.
Topics: Aged; Antihypertensive Agents; Blood Pressure; China; Electrocardiography; Endpoint Determination; F | 2009 |
Perindopril for the treatment of hypertension.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardi | 2011 |
Combination perindopril/indapamide for the treatment of hypertension: a review.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Humans; Hyperte | 2011 |
What matters in ADVANCE and ADVANCE-ON.
Topics: Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diabete | 2012 |
[New guidelines for hypertension in Russia--a priority of combined treatment].
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Drug Synergism | 2012 |
Position of indapamide, a diuretic with vasorelaxant activities, in antihypertensive therapy.
Topics: Antihypertensive Agents; Diuretics; Humans; Hypertension; Indapamide; Vasodilator Agents | 2012 |
The Hypertension in the Very Elderly Trial - latest data.
Topics: Aged, 80 and over; Antihypertensive Agents; Cognition Disorders; Delayed-Action Preparations; Dement | 2013 |
[Arterial stiffness, wave reflections and myocardial protection: the REASON project].
Topics: Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diastole; Drug Combinations; Humans; Hy | 2003 |
[Structural and functional changes of the microcirculation in hypertension: influence of pharmacological therapy].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Age | 2003 |
Clinical role of Natrilix SR in the treatment of at-risk hypertensive patients.
Topics: Delayed-Action Preparations; Humans; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Risk F | 2003 |
Very-low-dose combination: a first-line choice for the treatment of hypertension?
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2003 |
Very-low-dose combination of perindopril and indapamide: efficacy on blood pressure and target-organ damage.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus | 2003 |
A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; | 2004 |
Efficacy of indapamide 1.5 mg, sustained release, in the lowering of systolic blood pressure.
Topics: Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diabetes Me | 2004 |
A meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive | 2005 |
[Management of hypertension in elderly patients with stroke].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; | 2005 |
Indapamide sustained release: a review of its use in the treatment of hypertension.
Topics: Animals; Antihypertensive Agents; Clinical Trials as Topic; Delayed-Action Preparations; Diuretics; | 2006 |
Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2006 |
Pulse pressure reduction and cardiovascular protection.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Di | 2006 |
Renal protection in diabetic patients: benefits of a first-line combination of perindopril-indapamide (Preterax).
Topics: Albuminuria; Antihypertensive Agents; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic | 2006 |
Managing hypertension in high-risk patients: lessons and promises from the STRATHE and ADVANCE trials.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2006 |
Ventricular hypertrophy and hypertension: prognostic elements and implications for management.
Topics: Adrenergic Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convert | 2006 |
Hypertension: which aspects of hypertension should we impact on and how?
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug | 2006 |
Delapril plus indapamide: a review of the combination in the treatment of hypertension.
Topics: Animals; Antihypertensive Agents; Drug Combinations; Humans; Hypertension; Indans; Indapamide | 2007 |
New insights from ADVANCE.
Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus, T | 2007 |
The need for combination antihypertensive therapy to reach target blood pressures: what has been learned from clinical practice and morbidity-mortality trials?
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; | 2007 |
[The prevention of the hypertension related damage in type-2 diabetes: the first step of the ADVANCE trial].
Topics: Antihypertensive Agents; Blood Pressure; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Com | 2008 |
The possible mode of action of indapamide: a review.
Topics: Benzothiadiazines; Biological Transport; Blood Pressure; Body Weight; Cardiac Output; Diuresis; Diur | 1983 |
Indapamide: a review.
Topics: Aged; Arrhythmias, Cardiac; Blood Glucose; Blood Pressure; Diuretics; Electrolytes; Humans; Hyperten | 1983 |
A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides.
Topics: Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Diuretics; Dose-Response Relationship, D | 1996 |
Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis.
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Female; Humans; H | 1996 |
Comparative effects of indapamide and captopril on blood pressure and albumin excretion rate in diabetic microalbuminuria.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calc | 1996 |
Chinese contribution to trials on antihypertensive therapy.
Topics: Antihypertensive Agents; Calcium Channel Blockers; China; Clinical Trials as Topic; Humans; Hyperten | 1996 |
[Value of diuretics in hypertension].
Topics: Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; H | 1996 |
Hyperlipidemia of diuretic therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cere | 1998 |
Perindopril 2mg/indapamide 0.625mg. Fixed low-dose combination.
Topics: Animals; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug C | 1999 |
Pharmacological properties of indapamide. Rationale for use in hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Dose-Response Relationsh | 1999 |
Clinical implications of indapamide sustained release 1.5 mg in hypertension.
Topics: Age Factors; Aged; Antihypertensive Agents; Clinical Trials as Topic; Delayed-Action Preparations; D | 1999 |
Concluding remarks. Pursuit of the optimal outcome in hypertension.
Topics: Age Factors; Antihypertensive Agents; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Re | 1999 |
[Renaissance of diuretics in the treatment of hypertension].
Topics: Antihypertensive Agents; Delayed-Action Preparations; Diuretics; Dose-Response Relationship, Drug; D | 1999 |
Clinical positioning of indapamide sustained release 1.5mg in management protocols for hypertension.
Topics: Clinical Trials as Topic; Delayed-Action Preparations; Diuretics; Humans; Hypertension; Indapamide; | 2000 |
Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension.
Topics: Adult; Age Factors; Aged; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; | 2001 |
Very-low-dose combination of perindopril and indapamide as a novel strategy in first-line management of hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Rel | 2001 |
Metabolic profile of indapamide sustained-release in patients with hypertension: data from three randomised double-blind studies.
Topics: Adolescent; Adult; Aged; Blood Glucose; Creatinine; Delayed-Action Preparations; Diuretics; Double-B | 2001 |
Blood pressure and stroke; the PROGRESS trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; Humans | 2001 |
Indapamide: a diuretic of choice for the treatment of hypertension?
Topics: Blood Glucose; Humans; Hyperlipidemias; Hypertension; Hypokalemia; Indapamide; Meta-Analysis as Topi | 1991 |
[Long-term effects of indapamide in left ventricular hypertrophy in patients with hypertension].
Topics: Adult; Aged; Cardiomegaly; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Middle A | 1990 |
Biochemical, endocrine, and mineral effects of indapamide in black women.
Topics: Adult; Black People; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hypertension; Indapami | 1990 |
Cardiovascular protective properties of indapamide.
Topics: Blood Vessels; Diuretics; Heart; Heart Diseases; Hemodynamics; Humans; Hypertension; Indapamide; Pro | 1990 |
Beneficial effects of indapamide on lipoproteins and apoproteins in ambulatory hypertensive patients.
Topics: Apoproteins; Diuretics; Humans; Hypertension; Indapamide; Lipoproteins | 1990 |
Quality of life during treatment of hypertensive patients with diuretics.
Topics: Diuretics; Female; Humans; Hypertension; Indapamide; Male; Quality of Life | 1990 |
Lipoproteins during antihypertensive therapy. Study supported by the Swiss National Science Foundation.
Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Diuretics; Humans; Hypertension; Indapamide; Lipopro | 1989 |
Effects of diuretic drugs on the lipid profile.
Topics: Benzothiadiazines; Cholesterol; Diuretics; Drug Combinations; Humans; Hypertension; Indapamide; Lipo | 1988 |
Sodium and large arteries in hypertension. Effects of indapamide.
Topics: Aging; Arteries; Blood Pressure; Diuretics; Humans; Hypertension; Indapamide; Pulse; Sodium; Vascula | 1988 |
Effect of indapamide on phosphate metabolism and vascular reactivity.
Topics: Animals; Blood Pressure; Diuretics; Humans; Hypertension; In Vitro Techniques; Indapamide; Phosphate | 1988 |
271 trials available for indapamide and Hypertension
| Article | Year |
|---|---|
Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial.
Topics: Amlodipine; Antihypertensive Agents; Australia; Bisoprolol; Blood Pressure; Double-Blind Method; Dru | 2021 |
Cardioprotective potential of chronopharmacotherapy in patients with arterial hypertension who had a transient ischemic attack.
Topics: Diastole; Humans; Hypertension; Indapamide; Ischemic Attack, Transient; Ventricular Function, Left | 2021 |
The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study.
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Humans; Hyperten | 2022 |
Evaluation of Clinical Acceptability of Perindopril / Indapamide Single-pill Combination in Moderate to Severe Hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Indapamide; India; | 2019 |
The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE.
Topics: Adult; Aged; Body-Weight Trajectory; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Combin | 2020 |
Long-term effect of the perindopril/indapamide/amlodipine single-pill combination on left ventricular hypertrophy in outpatient hypertensive subjects.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Follow | 2019 |
Assessment of suitable antihypertensive therapies: Combination with high-dose amlodipine/irbesartan vs triple combination with amlodipine/irbesartan/indapamide (ASAHI-AI study).
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperten | 2020 |
Blood-pressure Lowering Efficacy and Safety of Perindopril / Indapamide / Amlodipine Single-pill Combination in Hypertensive Patients: Phase III Trial in India.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Indapa | 2020 |
Ultra-low-dose quadruple combination blood pressure-lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol.
Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Bisoprolol; Calcium Channel Blocke | 2021 |
Effect of Perindopril/Indapamide on Cerebral Blood Flow in Middle-Aged, Treatment-Naïve Patients with Hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cerebro | 2020 |
Comparison between the effects of hydrochlorothiazide and indapamide on the kidney in hypertensive patients inadequately controlled with losartan.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Creatinine; Female; Humans; Hydrochlorothiazide; Hype | 2017 |
Blood pressure-lowering efficacy of indapamide SR/amlodipine combination in older patients with hypertension: A post hoc analysis of the NESTOR trial (Natrilix SR vs Enalapril in Hypertensive Type 2 Diabetics With Microalbuminuria).
Topics: Aged; Aged, 80 and over; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes | 2017 |
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension | 2019 |
Response of 1,5-anhydroglucitol level to intensive glucose- and blood-pressure lowering interventions, and its associations with clinical outcomes in the ADVANCE trial.
Topics: Aged; Antihypertensive Agents; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 2; Drug Therapy, | 2019 |
Short-term effects of perindopril-amlodipine vs perindopril-indapamide on blood pressure control in sub-Saharan type 2 diabetic individuals newly diagnosed for hypertension: A double-blinded randomized controlled trial.
Topics: Africa South of the Sahara; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Moni | 2019 |
Effects of antihypertensive drugs on central blood pressure in humans: a preliminary observation.
Topics: Aged; Amlodipine; Antihypertensive Agents; Aorta; Arterial Pressure; Benzimidazoles; Biphenyl Compou | 2013 |
Increased pulse pressure linked to dementia: further results from the Hypertension in the Very Elderly Trial - HYVET.
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cognition; Dementia; Double-Blind Method | 2013 |
Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, T | 2014 |
Efficacy of single-pill perindopril/indapamide in patients with hypertension and type 2 diabetes.
Topics: Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Comorbidity; Diabetes Mellitus, Type 2; | 2014 |
The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes.
Topics: Aged; Alcohol Drinking; Antihypertensive Agents; Coronary Disease; Diabetes Mellitus, Type 2; Diabet | 2014 |
Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Drug Combin | 2014 |
Can we identify response markers to antihypertensive drugs? First results from the IDEAL Trial.
Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteria | 2015 |
[Comparison pharmacoeconomics organoprotection using fixed combinations of antihypertensive drugs].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Economics, Pharmaceutical; Enalapril; Female; Hu | 2014 |
Subgroup and per-protocol analyses from the Hypertension in the Very Elderly Trial.
Topics: Age Factors; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; De | 2014 |
Follow-up of blood-pressure lowering and glucose control in type 2 diabetes.
Topics: Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Female; Follow | 2014 |
The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: results of a randomized trial.
Topics: Blood Pressure; Carotid Arteries; Diabetes Mellitus, Type 2; Diuretics; Dose-Response Relationship, | 2014 |
Prevention of metabolic disorders with telmisartan and indapamide in a Chinese population with high-normal blood pressure.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; China; Double-Blind Method | 2015 |
Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine.
Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pres | 2015 |
Treatment of Hypertensive Patients With Diabetes and Microalbuminuria With Combination Indapamide SR/Amlodipine: Retrospective Analysis of NESTOR.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Ca | 2015 |
No evidence that frailty modifies the positive impact of antihypertensive treatment in very elderly people: an investigation of the impact of frailty upon treatment effect in the HYpertension in the Very Elderly Trial (HYVET) study, a double-blind, placeb
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Comorbidity; Double-Blind Method; Drug T | 2015 |
[Direct comparison of endothelial and metabolic effects of perindopril combination with indapamide retard or hydrochlorothiazide].
Topics: Aged; Antihypertensive Agents; Biological Availability; Blood Pressure; Carbohydrate Metabolism; Del | 2014 |
Effects of a selective aldosterone blocker and thiazide-type diuretic on blood pressure and organ damage in hypertensive patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Blood Pressure; Blood Pressure Determination; Calcium Channel Blo | 2015 |
[Possibilities of Correction of Endothelial Dysfunction at the Background of Combined Antihypertensive Therapy in Patients With Arterial Hypertension and Type 2 Diabetes].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Diabetes Mellitus, Type 2; Dos | 2015 |
Antihypertensive therapy increases natural immunity response in hypertensive patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hydrochlorothiazi | 2015 |
The advantages of combination therapy on hypertension: development of immediate release perindopril-indapamide tablet and assessment of bioequivalence studies.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Area Under Curve; Chemistry, | 2016 |
Antihypertensive treatment decreases arterial stiffness at night but not during the day. Results from the Hypertension in the Very Elderly Trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Mo | 2017 |
Fixed-Dose Triple Combination of Antihypertensive Drugs Improves Blood Pressure Control: From Clinical Trials to Clinical Practice.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Ca | 2017 |
Effects of a fixed-dose ACE inhibitor-diuretic combination on ambulatory blood pressure and arterial properties in isolated systolic hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calci | 2008 |
Blood pressure normalization by fixed perindopril/indapamide combination in hypertensive patients with or without associate metabolic syndrome: results of the OPTIMAX 2 study.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; | 2008 |
Lowering of brachial pulse pressure in 9379 hypertensives with type 2 diabetes and reduction of cardiovascular events.
Topics: Antihypertensive Agents; Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cohort Studies; D | 2008 |
Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial.
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cognition; Dementia; Double-Blind Method | 2008 |
Blood pressure response under chronic antihypertensive drug therapy: the role of aortic stiffness in the REASON (Preterax in Regression of Arterial Stiffness in a Controlled Double-Blind) study.
Topics: Aged; Antihypertensive Agents; Aortic Diseases; Atenolol; Blood Pressure; Double-Blind Method; Drug | 2009 |
Lowering blood pressure reduces renal events in type 2 diabetes.
Topics: Age of Onset; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2009 |
Fixed dose combination of perindopril and indapamide improves peripheral vascular function in essential hypertensive patients.
Topics: Adult; Antihypertensive Agents; Atenolol; Brachial Artery; Drug Combinations; Female; Humans; Hypert | 2009 |
Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis.
Topics: Aged, 80 and over; Antihypertensive Agents; Cardiovascular Diseases; Cognition Disorders; Comorbidit | 2009 |
Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study.
Topics: Aged; Antihypertensive Agents; Atrial Fibrillation; Blood Glucose; Confidence Intervals; Diabetic An | 2009 |
[Combined antihypertensive treatment of patients with hypertension and type 2 diabetes mellitus].
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Diabet | 2009 |
Long term monitoring in patients receiving treatment to lower blood pressure: analysis of data from placebo controlled randomised controlled trial.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Diastole; Female; Humans; Hyp | 2009 |
[Hypotensive and metabolic effect of indapamide and perindopril in patients with type 2 diabetes and arterial hypertensia].
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Indapamide; Male; | 2009 |
Treating hypertension by rational use of diuretics: results of the Russian ARGUS-2 Study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations | 2009 |
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial.
Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; | 2009 |
[Effect of arterial hypertension on sexual health of men and their quality of life. Resuts of BOLERO study].
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Indapamide; Male; Middle Aged; Progno | 2009 |
Combination of an ACE inhibitor and indapamide improves blood pressure control, but attenuates the beneficial effects of ACE inhibition on plasma adiponectin in patients with essential hypertension.
Topics: Adiponectin; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomark | 2009 |
Blood pressure reduction for the secondary prevention of stroke: a Chinese trial and a systematic review of the literature.
Topics: Aged; Antihypertensive Agents; Blood Pressure; China; Electrocardiography; Endpoint Determination; F | 2009 |
[Combined antihypertensive therapy in patients with arterial hypertension and type 2 diabetes].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Diabetes Melli | 2009 |
Combination therapy with angiotensin-converting enzyme inhibitors and indapamide impairs glucose tolerance in Chinese hypertensive patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Body Mass Index; C | 2010 |
The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; D | 2010 |
[Comparative efficiency of indapamide combinations with various derivaties of calcium antagonists in patients with arterial hypertension].
Topics: Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Bloc | 2010 |
Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; | 2010 |
Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged, 80 and over; Antihypertensive Agents; Cardiovascular Diseases; Dementia; Depression; Female; G | 2010 |
Effects of blood pressure control with perindopril/indapamide on the microcirculation in hypertensive patients.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Capillaries; Cross-Over Studies; Cro | 2010 |
Management of high blood pressure in type 2 diabetes: perindopril/indapamide fixed-dose combination and the ADVANCE trial [corrected].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics | 2010 |
The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged, 80 and over; Aging; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Fractu | 2010 |
Modelling cognitive decline in the Hypertension in the Very Elderly Trial [HYVET] and proposed risk tables for population use.
Topics: Aged, 80 and over; Antihypertensive Agents; Cognition Disorders; Double-Blind Method; Female; Humans | 2010 |
Monitoring adherence to medication by measuring change in blood pressure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Monitoring; Drug Therapy, | 2010 |
Cost-effectiveness of lowering blood pressure with a fixed combination of perindopril and indapamide in type 2 diabetes mellitus: an ADVANCE trial-based analysis.
Topics: Antihypertensive Agents; Australia; Blood Pressure; Cost-Benefit Analysis; Diabetic Angiopathies; Ho | 2010 |
Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arterioles; Blood | 2011 |
Responses of the ambulatory arterial stiffness index and other measures of arterial function to antihypertensive drugs.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Flow Velocity; Blood Pressure; Brachial Artery | 2011 |
Blood pressure control in the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Heart | 2012 |
[The ORIGINAL program main results].
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Am | 2011 |
Effects of blood pressure lowering on major vascular events among patients with isolated diastolic hypertension: the perindopril protection against recurrent stroke study (PROGRESS) trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Indapamide; Male; Middl | 2011 |
Effect of antihypertensive agents on blood pressure variability: the Natrilix SR versus candesartan and amlodipine in the reduction of systolic blood pressure in hypertensive patients (X-CELLENT) study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood | 2011 |
Immediate and late benefits of treating very elderly people with hypertension: results from active treatment extension to Hypertension in the Very Elderly randomised controlled trial.
Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; China; Confidence Int | 2011 |
Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; D | 2012 |
Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.
Topics: Age Factors; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Ag | 2013 |
[The impact of antihypertensive therapy on cerebral hemodynamics in patients with metabolic syndrome].
Topics: Antihypertensive Agents; Biological Availability; Blood Pressure Monitoring, Ambulatory; Brain; Cere | 2012 |
Blood pressure and metabolic efficacy of fixed-dose combination of perindopril and indapamide in everyday practice.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Indapamide; | 2013 |
Gender influence on the dose-ranging of a low-dose perindopril-indapamide combination in hypertension: effect on systolic and pulse pressure.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Data | 2002 |
Comparison of indapamide and low-dose hydrochlorothiazide monotherapy in black patients with mild to moderate hypertension.
Topics: Adult; Aged; Analysis of Variance; Black People; Blood Pressure Determination; Dose-Response Relatio | 2002 |
Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Double-Blind Method; Drug Combina | 2002 |
[Management of hypertensive patients with left ventricular hypertrophy].
Topics: Adrenergic alpha-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent | 2002 |
[Arterial hypertension in elderly individuals].
Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; | 2002 |
[Treatment of hypertensive type 2 diabetes patients with microalbuminuria].
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Creatinine; Data Int | 2002 |
[Combination of low-dose perindopril/indapamide versus atenolol in the hypertensive patient. Effects on systolic pressure and arterial hemodynamics. REASON Study].
Topics: Atenolol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemodynamics; Humans; Hyperte | 2002 |
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventr | 2002 |
[Tolerability and efficacy of retard form of indapamide in the treatment of hypertension in elderly patients (results of multicenter open non-comparative trial in Russian program ARGUS)].
Topics: Aged; Delayed-Action Preparations; Diuretics; Drug Tolerance; Female; Humans; Hypertension; Indapami | 2002 |
Evaluation of the efficacy and tolerability of the combination delapril plus indapamide in the treatment of mild to moderate essential hypertension: a randomised, multicentre, controlled study.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopri | 2003 |
[CEA comprehensive evaluation for Western and traditional Chinese hypotensive drugs].
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Benzazepines; Cost-Benefit Anal | 2001 |
[Arterial stiffness, wave reflections and myocardial protection: the REASON project].
Topics: Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diastole; Drug Combinations; Humans; Hy | 2003 |
[ADVANCE study: objectives, design and current status].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Press | 2003 |
Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cerebrovasc | 2003 |
Effect of indapamide SR on microalbuminuria--the NESTOR study (Natrilix SR versus Enalapril Study in Type 2 diabetic hypertensives with micrOalbuminuRia)--rationale and protocol for the main trial.
Topics: Adult; Aged; Albuminuria; Clinical Protocols; Creatine; Delayed-Action Preparations; Diabetes Mellit | 2003 |
Improvement of impaired coronary vasodilator reserve in hypertensive patients by low-dose ACE inhibitor/diuretic therapy: a pilot PET study.
Topics: Angiotensin-Converting Enzyme Inhibitors; Coronary Circulation; Diuretics; Drug Therapy, Combination | 2003 |
Effect of indapamide SR in the treatment of hypertensive patients with type 2 diabetes.
Topics: Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Delayed-Action Preparations; Diabetes | 2003 |
Comparative metabolic effects of hydrochlorothiazide and indapamide in hypertensive diabetic patients receiving ACE inhibitor therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cross-Over Studie | 2003 |
[Arterial hypertension in menopausal women: Clinical, functional, and pharmaco-economical aspects].
Topics: Circadian Rhythm; Diuretics; Drug Combinations; Drug Therapy, Combination; Estradiol; Female; Heart; | 2003 |
Effects of a perindopril-based blood pressure-lowering regimen on the risk of recurrent stroke according to stroke subtype and medical history: the PROGRESS Trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Brain Ische | 2004 |
Mechanism(s) of selective systolic blood pressure reduction after a low-dose combination of perindopril/indapamide in hypertensive subjects: comparison with atenolol.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Drug Therapy, Combination; Female; Follow-Up Stud | 2004 |
Twenty-four-hour ambulatory blood pressure monitoring efficacy of perindopril/indapamide first-line combination in hypertensive patients: the REASON study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitor | 2004 |
[Severe heart failure: treatment optimisation and monitoring using plasma NT-proBNP levels--an useful tool in clinical practice].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol | 2004 |
Effects of a low dose of indapamide, a diuretic, given daily or every-other-day on blood pressure and metabolic parameters.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Dos | 2004 |
Reductions in the risks of recurrent stroke in patients with and without diabetes: the PROGRESS Trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Comorbidity; Diabetes Compl | 2004 |
Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry.
Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black Pe | 2004 |
Selective reduction of cardiac mass and central blood pressure on low-dose combination perindopril/indapamide in hypertensive subjects.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Carotid Arteries; D | 2004 |
Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study.
Topics: Aged; Albuminuria; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Doubl | 2004 |
Regression of left ventricular mass in hypertensive patients treated with perindopril/indapamide as a first-line combination: the REASON echocardiography study.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Drug Therapy, Combi | 2004 |
[Evaluation of the antihypertensive efficacy and tolerability of fixed very low-dose perindopril/indapamid combination in patients with mild to moderate hypertension. Results of a Czech and Slovak multicentric study].
Topics: Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Echocardiography; Female; Hum | 2004 |
Comparison of different therapeutic strategies in hypertension: a low-dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped-care approach.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; | 2004 |
Effect of indapamide on urinary calcium excretion in patients with and without urinary stone disease.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Metabolism Disorders; Creatinine; D | 2005 |
Evaluation of long-term efficacy and acceptability of indapamide SR in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Amlodipine; Analysis of Variance; Antihypertensive Agents; Double-Blind Met | 2005 |
Efficacy of combination antihypertensive therapy with low-dose indapamide: assessment by blood pressure self-monitoring at home.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihyperte | 2005 |
[Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk].
Topics: Antihypertensive Agents; Captopril; Cardiomegaly; Female; Heart Ventricles; Humans; Hydrochlorothiaz | 2005 |
[Effect of various generics of indapamide on surrogate end points during treatment of hypertension in the elderly].
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Double-Blind Method; Drugs, Gene | 2005 |
Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Atrial Fibr | 2005 |
Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination | 2005 |
[Utility of extended release indapamide in the treatment of hypertension in at risk elderly: extended release study].
Topics: Aged; Antihypertensive Agents; Female; Humans; Hypertension; Indapamide; Male; Prospective Studies; | 2005 |
[The comparison of the effect of enalapril and indapamide on the peripheral blood pressure and central blood pressure through pulse wave analysis].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Doub | 2005 |
[Comparative efficacy of fixed dose combinations of perindopril with indapamide and captopril with hydrochlorothiazide in patients with high risk hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Dose-Re | 2005 |
Rationale and methodology of monitoring ambulatory blood pressure and arterial compliance in the Hypertension in the Very Elderly Trial.
Topics: Aged, 80 and over; Arteries; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Clinical Protoco | 2006 |
Indapamide SR versus candesartan and amlodipine in hypertension: the X-CELLENT Study.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensiv | 2006 |
[Effect of twelve-month combined therapy with perindopril and indapamide on the level of blood pressure and left ventricular hypertrophy in patients with hypertensive disease].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Comorbidity; Diuretics; Drug Therapy, Combina | 2006 |
ADVANCE: breaking new ground in type 2 diabetes.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics | 2006 |
Efficacy and tolerability of the perindopril/indapamide combination therapy for hypertension: the PRIMUS study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; | 2006 |
Effects of valsartan and indapamide on plasma cytokines in essential hypertension.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chemokine CCL2; Chemokine C | 2006 |
The impact of one or two missed doses on the duration of action of combined perindopril and indapamide.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertensio | 2007 |
Efficacy of indapamide SR compared with enalapril in elderly hypertensive patients with type 2 diabetes.
Topics: Aged; Albuminuria; Antihypertensive Agents; Diabetes Mellitus, Type 2; Enalapril; Female; Humans; Hy | 2007 |
Superior effect of an angiotensin-converting enzyme inhibitor over a diuretic for reducing aortic systolic pressure.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Aorta; Blood Pressure; Diuretics; Double-Blind Meth | 2007 |
Persistence of the antihypertensive effect of low-dose combination therapy in mild hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Mo | 2006 |
ADVANCE: lessons from the run-in phase of a large study in type 2 diabetes.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2006 |
[Problems of a physician-patient interaction and control of arterial hypertension in Russia. Main results of scientific-practical program ARGUS-2].
Topics: Adult; Aged; Antihypertensive Agents; Data Interpretation, Statistical; Delayed-Action Preparations; | 2007 |
[Possibilities of using indices of vascular wall function as markers of negative metabolic effects of treatment with thiazide diuretics in patients with essential hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Endothelium, Vascular; Female; Humans; Hydroch | 2007 |
Blood pressure normalization in a large population of hypertensive patients treated with perindopril/indapamide combination: results of the OPTIMAX trial.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Follow- | 2007 |
Vascular outcome in type 2 diabetes: an ADVANCE?
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics; Drug | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Me | 2007 |
[Advanced credit: patient enrolling and therapy initiation in the ADVANCE trial].
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Complications; Diabete | 2007 |
[Clinical and vascular effects of ACE inhibitor enalapril in combination with thiaside-like diuretic indapamide in hypertensive outpatients. Results of the multicenter trial POEMA].
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Dose-Response Relationship, Dru | 2007 |
Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, | 2007 |
[The activity of nonspecific inflammation in hypertensive patients].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Pressure; C-Reactive Protei | 2007 |
[ADVANCE: a morbidity mortality study of diabetes and hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; | 2008 |
[Indapamide retard and enalapril in patients with arterial hypertension: hypotensive effectiveness and effect on endothelial function].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Enalapril; Endothelium, Vascular | 2007 |
[Effect of a fixed combination of perindopril and indapamide on 24-hour blood pressure profile, morpho-functional parameters of the heart, heart rate variability, functional state of the kidney, and quality of life in patients with arterial hypertension c
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertensi | 2007 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Treatment of hypertension in patients 80 years of age or older.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Romanian subjects entered in the hypertension in the very elderly trial (HYVET).
Topics: Age Distribution; Aged, 80 and over; Antihypertensive Agents; Body Weights and Measures; Female; Hea | 2006 |
Fixed combination of perindopril and indapamide at low dose improves endothelial function in essential hypertensive patients after acute administration.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Circulation; Cross-Over Stu | 2008 |
Efficacy of a very-low-dose combination of perindopril and indapamide--preterax compared with cilazapril monotherapy in patients with inadequate blood pressure control--a randomized, double-blind, add-on study.
Topics: Adult; Aged; Cilazapril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertensio | 2008 |
The use of indapamide in resistant hypertensive therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Diuretics; Drug Therapy, Combinat | 1981 |
Effects of indapamide and various diuretics alone or combined with beta-blockers on serum lipoproteins.
Topics: Adrenergic beta-Antagonists; Adult; Apolipoproteins; Apolipoproteins B; Cholesterol; Cholesterol, HD | 1983 |
The treatment of hypertension with indapamide alone or in combination with other drugs.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; | 1983 |
Hypertension in diabetic patients--an evaluation of indapamide treatment.
Topics: Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Diuretics; Female; Humans; Hyperte | 1983 |
Multicenter dose-response study of the effect of indapamide in the treatment of patients with mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Dizziness; Dose-Response Relations | 1983 |
Clinical efficacy and safety of indapamide in essential hypertension.
Topics: Adult; Aged; Animals; Clinical Trials as Topic; Diuretics; Double-Blind Method; Electrolytes; Humans | 1983 |
Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment.
Topics: Aldosterone; Blood Pressure; Body Weight; Diuretics; Hemodynamics; Humans; Hypertension; Indapamide; | 1983 |
Long-term experience with indapamide.
Topics: Adult; Aged; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hydrochloroth | 1983 |
Indapamide in hypertension: results of a French multi-centre study in ambulant subjects.
Topics: Aged; Ambulatory Care; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Diuretics; Heart Rat | 1983 |
Diuretic and cardiovascular effects of indapamide in hypertensive subjects: a dose-response curve.
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuresis; Diuretics; Dose-Response Rel | 1983 |
Multi-centre clinical investigation of indapamide in the United States: a review.
Topics: Antihypertensive Agents; Biological Availability; Clinical Trials as Topic; Diuretics; Drug Therapy, | 1983 |
Indapamide in the treatment of essential arterial hypertension: results of a controlled study.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Electrolytes; Femal | 1983 |
Indapamide versus hydrochlorothiazide in essential hypertension: measurement of peripheral resistance using plethysmography.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Epinephrine; | 1983 |
Indapamide and atenolol in the treatment of hypertension: double-blind comparative and combination study.
Topics: Adult; Atenolol; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination | 1983 |
[A crossover comparison of the antihypertensive effects of indapamide and pindolol].
Topics: Adult; Aged; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hypertension; | 1983 |
Indapamide (Lozol)--a new antihypertensive agent and diuretic.
Topics: Clinical Trials as Topic; Diuretics; Edema; Humans; Hypertension; Indapamide | 1984 |
Indapamide versus beta-blocker therapy: a double-blind, crossover study in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Hemod | 1984 |
Haemodynamic changes in peripheral arterial circulation during antihypertensive treatment with captopril, methyldopa and indapamide.
Topics: Adult; Arteries; Captopril; Diuretics; Female; Hemodynamics; Humans; Hypertension; Indapamide; Male; | 1984 |
Indapamide in the treatment of mild to moderate hypertension.
Topics: Clinical Trials as Topic; Diuretics; Female; Humans; Hypertension; Indapamide; Male | 1984 |
The efficacy of indapamide in hypertensive patients failing to respond to a beta-blocker alone.
Topics: Adult; Aged; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Indapamide; | 1984 |
Indapamide in the stepped-care treatment of obese hypertensive patients.
Topics: Adult; Aged; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; | 1983 |
Biochemical changes in black and Indian hypertensive patients on diuretic therapy.
Topics: Adult; Amiloride; Blood Glucose; Blood Pressure; Chlorthalidone; Creatinine; Diuretics; Drug Therapy | 1983 |
[Controlled study of the anti-hypertensive effects of indapamide, metoprolol and their combination in patients with essential arterial hypertension].
Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Exercise T | 1982 |
[Controlled study of antihypertensive effects of indapamide and metoprolol and their combination in patients with essential arterial hypertension].
Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; He | 1982 |
Effect of indapamide on the baroreceptor reflex in essential hypertension.
Topics: Adult; Blood Pressure; Diuretics; Female; Heart Rate; Humans; Hypertension; Indapamide; Male; Middle | 1983 |
Indapamide in a single daily dose in the treatment of hypertension. A multicentre trial in private practice.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Female; Humans; Hypertension; Inda | 1981 |
Clinical trial on Indapamide in the treatment of hypertension.
Topics: Adult; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Diuretics; Female; Humans; Hypertens | 1981 |
Indapamide in the treatment of essential arterial hypertension in the elderly.
Topics: Aged; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Female; Humans; Hypertension; In | 1981 |
A study comparing indapamide with cyclopenthiazide in geriatric patients.
Topics: Aged; Antihypertensive Agents; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Female; Humans | 1981 |
A multicentre open trial indapamide in general practice.
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Female; Humans; Hypertens | 1981 |
International multicentre study of indapamide in the treatment of essential arterial hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Female; Human | 1981 |
Echocardiographic evaluation of left ventricular function in patients showing an antihypertensive and biochemical response to indapamide.
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Echocardiography; Female; Heart | 1981 |
Indapamide and bendrofluazide: a comparison in the management of essential hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Diuretics; Electrolytes; Female; Humans; Hy | 1981 |
Effects of once daily indapamide and pindolol on blood pressure, plasma aldosterone concentration and plasma renin activity in a general practice setting.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diuretics; Family Practice; Heart Rate; Humans; Hypertensi | 1982 |
[International multicentre-study on indapamide in the treatment f essential arterial hypertension (author's transl)].
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Female; Humans; Hypert | 1982 |
Comparison of indapamide with thiazide diuretics in patients with essential hypertension.
Topics: Benzothiadiazines; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Indap | 1981 |
The effect of indapamide on muscle blood flow in hypertensive patients.
Topics: Antihypertensive Agents; Blood Pressure; Diuretics; Humans; Hypertension; Indapamide; Muscle, Smooth | 1981 |
Indapamide in ambulant treatment of hypertension: a comparative study with alpha-methyldopa.
Topics: Antihypertensive Agents; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Methyldopa | 1981 |
Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Combined Modality Therapy; Exerc | 1995 |
Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Enalapril; Female; France; Humans; Hydro | 1993 |
Regression of microalbuminuria: results of a controlled study, indapamide versus captopril.
Topics: Aged; Albuminuria; Analysis of Variance; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Femal | 1993 |
Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM.
Topics: Albuminuria; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Blood P | 1995 |
Comparison between the effects of indapamide and hydrochlorothiazide on creatinine clearance in patients with impaired renal function and hypertension.
Topics: Body Weight; Creatinine; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertensi | 1995 |
Sequential monotherapy of hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Cross-Over Studies; Drug | 1994 |
Efficacious response with lower dose indapamide therapy in the treatment of elderly patients with mild to moderate hypertension.
Topics: Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Indapami | 1995 |
Conversion from 2.5 mg to 1.25 mg indapamide in patients with mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Indapamide; Male; Mi | 1995 |
Lower dose diuretic therapy in the treatment of patients with mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Data Interpretation, Statistical; Double-Blind Method; Electrocardiogra | 1994 |
[Hypertension and well-being: a study with indapamide].
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Multivaria | 1994 |
[The effect of indapamide on cardiac dysfunction in patients with hypertension].
Topics: Adult; Aged; Blood Proteins; Cardenolides; Digoxin; Drug Therapy, Combination; Female; Humans; Hyper | 1993 |
[The insulin secretion and pharmaceutical interference in hypertensive patients and their normotensive children].
Topics: Adult; Aged; Blood Glucose; Captopril; Female; Glucose Tolerance Test; Humans; Hypertension; Indapam | 1993 |
[Regression of hypertrophy of the left ventricle in patients with hypertension after 6-month treatment with Fludex].
Topics: Blood Pressure; Cardiac Volume; Echocardiography; Electrocardiography; Female; Humans; Hypertension; | 1993 |
[Therapeutic benefit of a low dose of indapamide: results of a double-blind against placebo European controlled study].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Human | 1995 |
Post-stroke antihypertensive treatment study. A preliminary result.
Topics: Aged; Antihypertensive Agents; Cerebrovascular Disorders; China; Double-Blind Method; Female; Humans | 1995 |
Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients.
Topics: Administration, Cutaneous; Adult; Aged; Antihypertensive Agents; Clonidine; Cross-Over Studies; Diab | 1996 |
Comparative effects of indapamide and captopril on blood pressure and albumin excretion rate in diabetic microalbuminuria.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calc | 1996 |
Indapamide is superior to thiazide in the preservation of renal function in patients with renal insufficiency and systemic hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; | 1996 |
Regression of left ventricular hypertrophy in patients with essential hypertension. Results of 6 month treatment with indapamide.
Topics: Adult; Aged; Blood Pressure; Diuretics; Echocardiography; Female; Humans; Hypertension; Hypertrophy, | 1996 |
An equivalence study of the safety and efficacy of a fixed-dose combination of perindopril with indapamide versus fixed-dose combinations of captopril with hydrochlorothiazide and enalapril with hydrochlorothiazide in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Double-Blind Method; Dr | 1995 |
[Indapamide--a substitute diuretic for hypertensives with hyperglycemia and/or dyslipidemia].
Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Complications; Diabete | 1996 |
[Treatment of hypertension with indapamide 1.5 mg sustained-release form: synthesis of results].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Doubl | 1996 |
[Evaluation of trough/peak ratio of indapamide 1.5 mg sustained-release form assessed by ambulatory blood pressure monitoring].
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Delayed-Action | 1996 |
Evaluation of indapamide 1.25 mg once daily in elderly patients with mild to moderate hypertension.
Topics: Aged; Aged, 80 and over; Blood Pressure Determination; Diuretics; Double-Blind Method; Drug Administ | 1997 |
Fixed low-dose perindopril-indapamide combination in hypertensive patients with chronic renal failure.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Chronic Disease; Drug Therapy, Combination; Female | 1998 |
Twenty-four hour antihypertensive efficacy of indapamide, 1.5-mg sustained release: results of two randomized double-blind controlled studies.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulat | 1998 |
PROGRESS: Perindopril pROtection aGainst REcurrent Stroke Study: status in March 1997. PROGRESS Management Committee.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Cerebrovascular Disorders; Diuretics; Double-Blind M | 1998 |
Centralized echocardiogram quality control in a multicenter study of regression of left ventricular hypertrophy in hypertension.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Echocardiography; Enalapril; Female; Humans; Hy | 1998 |
[Changes in blood pressure 24 hour monitoring data and quality of life in patients with systolic hypertension treated with arifon].
Topics: Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Female; Follow-Up Studies; H | 1998 |
Low-dose antihypertensive therapy with 1.5 mg sustained-release indapamide: results of randomised double-blind controlled studies. European study group.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; De | 1998 |
Effects of delapril in combination with indapamide on blood pressure and left ventricular mass in elderly hypertensive patients.
Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Age | 1998 |
Low-dose diuretic and/or dietary sodium restriction when blood pressure is resistant to ACE inhibitor.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure | 1998 |
Efficacy and safety of an oral fixed low-dose perindopril 2 MG/indapamide 0.625 MG combination: a randomized, double-blind, placebo-controlled study in elderly patients with mild to moderate hypertension.
Topics: Administration, Oral; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Press | 1999 |
Effectiveness and metabolic effects of perindopril and diuretics combination in primary hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diuretics; Drug Therapy, C | 1999 |
PROGRESS - Perindopril Protection Against Recurrent Stroke Study: characteristics of the study population at baseline. Progress Management Committee.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cerebrovascular Disorders; Diuretics | 1999 |
Efficacy and safety of a fixed low-dose perindopril/indapamide combination in essential hypertension. A randomised controlled study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Press | 2000 |
Fixed low-dose combination therapy in hypertension--a dose response study of perindopril and indapamide.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Mo | 2000 |
Long-term efficacy of a new, fixed, very-low-dose angiotensin-converting enzyme-inhibitor/diuretic combination as first-line therapy in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pr | 2000 |
Effects of indapamide versus hydrochlorothiazide on plasma lipids and lipoproteins in hypertensive patients: a direct comparison.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Apolipoproteins B; Blood Pressure; Cholesterol; Di | 2000 |
Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Echocardiography; Enalapr | 2000 |
A comparison of indapamide SR 1.5 mg with both amlodipine 5 mg and hydrochlorothiazide 25 mg in elderly hypertensive patients: a randomized double-blind controlled study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Double-Blind Method; Female; Humans; H | 2001 |
Hypertension in the Very Elderly Trial (HYVET): protocol for the main trial.
Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Protocols; D | 2001 |
Antihypertensive efficacy and tolerability of low-dose perindopril/indapamide combination compared with losartan in the treatment of essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hyp | 2001 |
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination | 2001 |
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination | 2001 |
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination | 2001 |
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination | 2001 |
Study rationale and design of ADVANCE: action in diabetes and vascular disease--preterax and diamicron MR controlled evaluation.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Clinical Protocols; Diabetes Mellitus, Type 2; Diabe | 2001 |
Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/indapamide combination in hypertensive patient: a comparison with atenolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Ao | 2001 |
[Effects of perindopril and its combination with indapamide on risk stratification in patients with hypertension].
Topics: Antihypertensive Agents; Cardiovascular Diseases; Diuretics; Drug Therapy, Combination; Female; Huma | 2001 |
Amelioration of arterial properties with a perindopril-indapamide very-low-dose combination.
Topics: Antihypertensive Agents; Arteries; Brachial Artery; Carotid Arteries; Double-Blind Method; Drug Ther | 2001 |
Clinical benefit of very-low-dose perindopril-indapamide combination in hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drug Tolera | 2001 |
[Efficacy of 12-week monotherapy with arifon-retard of patients with isolated systolic hypertension].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Female; Humans; Hypertension; Indapamide; | 2002 |
The effects of the addition of losartan on uric acid metabolism in patients receiving indapamide.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hyp | 2000 |
Effects of antihypertensive therapy on hemorheological profiles in female hypertensive patients with initially low or high whole blood viscosity.
Topics: Antihypertensive Agents; Blood Pressure; Blood Viscosity; Enalapril; Erythrocytes; Female; Fibrinoge | 2002 |
A preliminary controlled evaluation of the antihypertensive effect of indapamide.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Diur | 1977 |
[Controlled multicentric trial of the antihypertensive agent indapamide].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Drug Evaluation; Female; | 1977 |
[Comparison using the double-blind method of the hypotensive action of indapamide and that of another salidiuretic agent, chlorthalidone].
Topics: Chlorthalidone; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Tolerance; Female; Hu | 1978 |
A placebo controlled single blind cross over trial to evaluate the antihypertensive activity of indapamide.
Topics: Adult; Aged; Diuretics; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Middle Aged | 1977 |
A comparative study of the activity of a new agent, indapamide, in essential arterial hypertension.
Topics: Aged; Chlorthalidone; Clinical Trials as Topic; Diuretics; Drug Evaluation; Drug Tolerance; Female; | 1975 |
[Indapamide in the treatment of hypertension in diabetes].
Topics: Diabetes Complications; Female; Humans; Hypertension; Indapamide; Male; Middle Aged | 1992 |
Effectiveness of indapamide versus enalapril as second-step therapy of systemic hypertension.
Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; H | 1992 |
Regression of left ventricular hypertrophy in hypertension with indapamide.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Humans; Hypertension; Indapamide; Middl | 1991 |
A double-blind, randomized, placebo-controlled comparison of the metabolic effects of low-dose hydrochlorothiazide and indapamide.
Topics: Blood Pressure; Body Weight; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; H | 1991 |
[Antihypertensive treatment: a combination of delapril, a new ACE-inhibitor, and indapamide].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Diuretics; Drug Evaluatio | 1990 |
Clinical efficacy and quality of life with indapamide alone or in combination with beta blockers or angiotensin-converting enzyme inhibitors.
Topics: Adult; Aged; Blood Pressure; Captopril; Consumer Behavior; Diuretics; Drug Combinations; Drug Tolera | 1990 |
Long-term effects of indapamide: final results of a two-year Italian multicenter study in systemic hypertension.
Topics: Adult; Aged; Atenolol; Blood Glucose; Blood Pressure; Diuretics; Drug Combinations; Drug Tolerance; | 1990 |
Quality of life during treatment of hypertensive patients with diuretics.
Topics: Diuretics; Female; Humans; Hypertension; Indapamide; Male; Quality of Life | 1990 |
Metabolic effects on indapamide.
Topics: Benzothiadiazines; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Metabolism; Randomized | 1990 |
Regression of left ventricular hypertrophy in hypertension: comparative effects of three different drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Female; Humans; Hypert | 1985 |
Comparison of indapamide and hydrochlorothiazide plus amiloride as a third drug in the treatment of arterial hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Double-Blind Method; Female; Heart Rate; Humans | 1989 |
[Cicletanine tolerance in hypertensive patients with metabolic disorders].
Topics: Antihypertensive Agents; Diuretics; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertensi | 1989 |
The effect of chronic antihypertensive therapy on the index of left ventricular mass in patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Atenolol; Cardiac Volume; Clinical Trials as Topic; Echocardiography | 1989 |
Hypertension in diabetes: effect of indapamide on glucose tolerance in diabetic hypertensive patients.
Topics: Clinical Trials as Topic; Diabetes Complications; Diuretics; Double-Blind Method; Humans; Hydrochlor | 1989 |
Platelet alpha 2-adrenoceptor modifications induced by long-term treatment with indapamide in essential hypertension.
Topics: Adult; Blood Platelets; Blood Pressure; Diuretics; Double-Blind Method; Drug Evaluation; Epinephrine | 1988 |
Effect of indapamide on serum and red cell cations, with and without magnesium supplementation, in subjects with mild hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Erythrocytes; Female; Humans; Hype | 1988 |
Arterial compliance and baroreceptor sensitivity after chronic treatment with indapamide.
Topics: Adult; Arteries; Diuretics; Humans; Hypertension; Indapamide; Middle Aged; Placebos; Pressoreceptors | 1988 |
Assessment of indapamide in elderly hypertensive patients with special emphasis on well-being.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Tolerance; Female | 1988 |
Analysis of well-being and 24-hour blood pressure recording in a comparative study between indapamide and captopril.
Topics: Adult; Aged; Blood Pressure; Captopril; Circadian Rhythm; Diuretics; Drug Evaluation; Female; Humans | 1988 |
Tolerability and well-being with indapamide in the treatment of mild-moderate hypertension. An Italian multicenter study.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Tolerance; Ele | 1988 |
Comparative study on the antihypertensive efficacy of torasemide and indapamide in patients with essential hypertension.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Creatinine; Diuretics; Double- | 1988 |
[Clinical effect of indapamide on hypertension].
Topics: Adult; Aged; Blood Glucose; Cholesterol; Clinical Trials as Topic; Diuretics; Double-Blind Method; F | 1987 |
Cardiovascular effects of indapamide in hypertensive patients with or without renal failure. A dose-response curve.
Topics: Cardiovascular System; Diuretics; Dose-Response Relationship, Drug; Drug Evaluation; Echocardiograph | 1988 |
Hypertension in elderly patients. A comparative study between indapamide and hydrochlorothiazide.
Topics: Aged; Blood Pressure; Diuretics; Drug Evaluation; Drug Tolerance; Humans; Hydrochlorothiazide; Hyper | 1988 |
[Comparative evaluation of the antihypertensive action of nitrendipine and indapamide].
Topics: Acebutolol; Aged; Antihypertensive Agents; Diuretics; Drug Evaluation; Drug Therapy, Combination; Fe | 1987 |
[Indapamide in the treatment of hypertension. A multicenter study of 3301 hypertensive patients].
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combinat | 1986 |
The efficacy and tolerance of indapamide in essential hypertension: a multi-centre study in 981 patients.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Creatinine; Diuretics; Follow-Up Studies; Fra | 1985 |
Double-blind comparison of indapamide with a placebo in hypertensive patients treated by practicing physicians.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Human | 1985 |
[Comparative effects of nifedipine and indapamide in the treatment of arterial hypertension].
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Diastole; Diuretics; Heart Rate; Human | 1985 |
Nadolol in combination with indapamide and xipamide in resistant hypertensives.
Topics: Adult; Aged; Blood Pressure; Diuretics; Drug Resistance; Drug Therapy, Combination; Female; Humans; | 1985 |
Clinical evaluation of muzolimine and indapamide during treatment for essential hypertension.
Topics: Adult; Aged; Blood Pressure; Diuretics; Electrocardiography; Female; Heart Rate; Humans; Hypertensio | 1985 |
289 other studies available for indapamide and Hypertension
| Article | Year |
|---|---|
Effectiveness of indapamide/amlodipine single-pill combination in patients with isolated systolic hypertension: post-hoc analysis of the ARBALET study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hypert | 2022 |
Use of Perindopril Arginine/Indapamide/Amlodipine in the Management of Hypertension in Two Sub-Saharan African Island Countries of Madagascar and Mauritius.
Topics: Amlodipine; Antihypertensive Agents; Arginine; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 2022 |
Hypertension and dyslipidemia treament in stroke.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2022 |
[Tactics of antihypertensive therapy during COVID-19 pandemic].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; COVID-19 | 2021 |
Incidence of severe hypokalaemia in patients taking indapamide.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diuretics; Female; Human | 2023 |
Adherence to Triple Single-Pill Combination of Perindopril/Indapamide/Amlodipine: Findings from Real-World Analysis in Italy.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; | 2023 |
A real-world analysis of outcomes and healthcare costs of patients on perindopril/indapamide/amlodipine single-pill vs. multiple-pill combination in Italy.
Topics: Adult; Amlodipine; Antihypertensive Agents; Drug Combinations; Health Care Costs; Humans; Hypertensi | 2024 |
A Spanish Family with Gordon Syndrome Due to a Variant in the Acidic Motif of
Topics: Acidosis; Adult; Child; Humans; Hyperkalemia; Hypertension; Indapamide; Thiazides; WNK Lysine-Defici | 2023 |
The impact of manual quality control review on the feasibility of central ambulatory blood pressure monitoring.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Feasibility Studies; Humans; Hype | 2020 |
[Antihypertensive and Vasoprotective Effects of Combined Pharmacotherapy in Patients with Arterial Hypertension and Prediabetes].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Com | 2020 |
[Therapeutic approaches to the Rational Use of trip-le combination therapy with a fixed combination of amlodipine, indapamide and perindopril arginine (TRIPLE COMBINATION) in patients with hypertension who do not control blood pressure on conventional tre
Topics: Aged; Amlodipine; Antihypertensive Agents; Arginine; Blood Pressure; Blood Pressure Monitoring, Ambu | 2020 |
Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs.
Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Drug Compoun | 2020 |
Acute bilateral myopia induced by Triplixam: a case report.
Topics: Adult; Choroidal Effusions; Ciliary Body; Humans; Hypertension; Indapamide; Male; Myopia | 2020 |
Effectiveness of Perindopril/Indapamide Single-Pill Combination in Uncontrolled Patients with Hypertension: A Pooled Analysis of the FORTISSIMO, FORSAGE, ACES and PICASSO Observational Studies.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hypertension; Inda | 2021 |
[Comorbidity of arterial hyperten-sion and tension-type headache].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Comorbidity; Drug Combinations; Humans; Hyperte | 2020 |
How to treat arterial hypertension in obese patients?
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diuretics; Humans; Hypertension; Indapamide; Obe | 2020 |
Combination blood pressure lowering in the presence or absence of background statin and aspirin therapy: a combined analysis of PROGRESS and ADVANCE Trials.
Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Drug Combinations; Humans; Hydroxymethylglutaryl-C | 2021 |
Renal denervation decreases blood pressure and renal tyrosine hydroxylase but does not augment the effect of hypotensive drugs.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Hypertension; Indapamide; Losartan; Male; Metop | 2017 |
The Antihypertensive Efficacy of the Triple Fixed Combination of Perindopril, Indapamide, and Amlodipine: The Results of the PETRA Study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; D | 2017 |
Prospective direct comparison of antihypertensive effect and safety between high-dose amlodipine or indapamide in hypertensive patients uncontrolled by standard doses of angiotensin receptor blockers and amlodipine.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biph | 2018 |
[Adherence of Patients to Antihypertensive Therapy With Combination of Perindopril and Indapamide According to Data of the FORSAGE Program].
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; D | 2017 |
[Indapamide SR/Amlodipine Fixed Dose Combination: Novel Approach to Effective Control of Systolic Arterial Pressure].
Topics: Amlodipine; Antihypertensive Agents; Arterial Pressure; Diuretics; Drug Combinations; Humans; Hypert | 2017 |
Efficacy and Tolerability of Fixed-Dose Combination Perindopril/Indapamide in Hypertensive Patients with a History of Stroke or Transient Ischemic Attack: PICASSO Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinati | 2018 |
Indapamide-induced bilateral choroidal effusion in pseudophakic patient.
Topics: Aged; Antihypertensive Agents; Cataract Extraction; Choroid Diseases; Diagnosis, Differential; Exuda | 2018 |
Diuretics and left ventricular hypertrophy regression: The relationship that we commonly forget.
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hyper | 2018 |
[Combined Therapy of Arterial Hypertension With Triple Fixed-Dose Combination of Amlodipine/Indapamide/Perindopril Arginine in Real Clinical Practice: the Organization and the Main Results of the DOKAZATEL'STVO (Proof) Study].
Topics: Academic Medical Centers; Aged; Amlodipine; Antihypertensive Agents; Arginine; Blood Pressure; Blood | 2018 |
[Cognitive Disorders and Dementia in Old Patients With Arterial Hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Cognition; Dementia; Humans; Hypertension; Indapamide | 2018 |
Interventricular vessel of the heart and diuretics.
Topics: Chlorthalidone; Diuretics; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, | 2019 |
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hypertension | 2018 |
The effectiveness of combination antihypertensive therapy in patients with arterial hypertension and additional risk factors: obesity and obstructive sleep apnea syndrome.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; H | 2018 |
Effectiveness and Adherence to Treatment with Perindopril/Indapamide/Amlodipine Single-Pill Combination in a Greek Population with Hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Greece; | 2019 |
[Single Pill Indapamide and Perindopril Arginine Combination: Optimal Coupling of Vascular Protection and Hemodynamic Risk Factors Reduction in Patients with Essential Arterial Hypertension].
Topics: Antihypertensive Agents; Arginine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hy | 2019 |
Utility of fixed-dose single tablet antihypertensive drug combinations in Cameroonians with type 2 diabetes and newly diagnosed hypertension.
Topics: Africa South of the Sahara; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, | 2019 |
Feasibility of 24-h central blood pressure monitoring: experience from multinational clinical trial assessing the efficacy of perindopril/indapamide/amlodipine.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Com | 2019 |
[The FORTISSIMO program: advantages of fixed full dose combination of perindopril arginine and indapamide in the treatment of poorly controlled arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Disease | 2013 |
[Not Available].
Topics: Activities of Daily Living; Antihypertensive Agents; Cognition Disorders; Female; Humans; Hypertensi | 2013 |
[Regional results of the program FORTISSIMO in Kazan].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Monitoring; Drug Resis | 2013 |
Evidence-based triple antihypertensive therapy yields lower mortality in older patients with diabetes mellitus.
Topics: Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Combinations; Female; Gl | 2014 |
Efficacy and tolerability of fixed-dose combination of perindopril/indapamide in type 2 diabetes mellitus: PICASSO trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Dru | 2014 |
Antihypertensive efficacy of triple combination perindopril/indapamide plus amlodipine in high-risk hypertensives: results of the PIANIST study (Perindopril-Indapamide plus AmlodipiNe in high rISk hyperTensive patients).
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure | 2014 |
[Antihypertensive treatment for patients 80 years and older].
Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Co | 2011 |
[Optimization of pharmacotherapy in patients with essential hypertension with neurohumoral modulators with consideration of data on heart rate variability].
Topics: Adult; Antihypertensive Agents; Cardiovascular Agents; Data Interpretation, Statistical; Drug Monito | 2013 |
[Pulse wave velocity and pulse pressure in patients with arterial hypertension].
Topics: Age Factors; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Indapamide | 2014 |
Triple combination therapy in hypertension: the antihypertensive efficacy of treatment with perindopril, amlodipine, and indapamide SR.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; De | 2014 |
Natriuresis and blood pressure reduction in hypertensive patients with diabetes mellitus: the NESTOR study.
Topics: Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Enalapril | 2015 |
Indapamide: is it the better diuretic for hypertension?
Topics: Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Potassium | 2015 |
[Fixed dose combination perindopril-indapamide-amlodipine (Triplixam) for the treatment of arterial hypertension].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Synergism; Humans; Hype | 2014 |
Economic evaluation of single-pill combination of indapamide and amlodipine in the treatment of arterial hypertension in the Polish setting.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Cost- | 2015 |
[Plasma Renin Activity and Potential of Indapamide Retard to Improve Control of Hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Follow-Up St | 2015 |
[The Results of Long-Term Observation of Patients Who Participated in the ADVANCE Trial].
Topics: Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Human | 2015 |
[The Strategy of Indapamide Retard Use in the Prevention of the Early Vascular Aging Syndrome].
Topics: Antihypertensive Agents; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indapamide | 2015 |
Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; | 2016 |
Full-dose Perindopril/Indapamide in the Treatment of Difficult-to-Control Hypertension: The FORTISSIMO Study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics; Drug Combinatio | 2017 |
Side effects and tolerability of combination blood pressure lowering according to blood pressure levels: an analysis of the PROGRESS and ADVANCE trials.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Drug Combinations; Female; | 2017 |
[Optimization of Control of Blood Pressure, Metabolic Disorders and Target Organs Protection With Fixed Perindopril and Indapamide Combination in Treated Patients With Arterial Hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; H | 2017 |
[Psychological Characteristics of Patients With Stress-induced Arterial Hypertension: a Violation of the Regulation of Emotions as a Central Link of Pathogenesis].
Topics: Acrylates; Adult; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Determination; | 2016 |
[Hronotherapy Aspects of Efficiency Azilsartan Medoxomil in Combination Therapy in Patients With Hypertension and Metabolic Syndrome].
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Benzimida | 2016 |
[How to Increase the Effectiveness of Antihypertensive Therapy in Clinical Practice: Results of the Russian Observational Program FORSAZH].
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Female; Heart | 2016 |
[Effectiveness of Dispersible Forms of Perindipril in Patients With Uncontrolled Arterial Hypertension in Clinical Practice].
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Diuretics; Female; Glomerular | 2016 |
[Comparative Assessment of Effects of Free and Fixed Combinations of Hypotensive Drugs on Quality of Life of Patients With Arterial Hypertension of High and Very High Risk].
Topics: Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Female; Humans; Hypertension; Indap | 2016 |
Slow release diuretics save lives.
Topics: Aged, 80 and over; Cardiovascular Diseases; Delayed-Action Preparations; Diuretics; Humans; Hyperten | 2008 |
[Survival advantage also in over 80-year-old patients].
Topics: Aged, 80 and over; Antihypertensive Agents; Germany; Humans; Hypertension; Indapamide; Perindopril; | 2008 |
A stunning day in hypertension research - Results of ONTARGET, ACCOMPLISH and HYVET.
Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Benzimidazoles; Benzoates; Clinical Trials as Top | 2008 |
[Need of antihypertensive therapy in patients aged 80 years or more].
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, C | 2008 |
Older age should not be a barrier to the treatment of hypertension.
Topics: Age Factors; Aged, 80 and over; Aging; Antihypertensive Agents; Cardiovascular Diseases; Drug Therap | 2008 |
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; Franc | 2008 |
[Treatment of hypertension in people over 80 years should not be discontinued].
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cause of Death; Female; Humans; Hyperten | 2008 |
Low-dose fixed combination of perindopril plus indapamide in the diabetic hypertensive population.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cross-Sectional Studies; Diabetic Angiopathies; Drug | 2008 |
Study shows benefit of hypertension help after 80.
Topics: Aged, 80 and over; Aging; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; In | 2008 |
You should treat patients over the age of 80 who have hypertension.
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2008 |
Management of older hypertensive patients.
Topics: Age Factors; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Ch | 2008 |
[Arterial hypertension in persons older than 80 years: the problem can be successfully solved].
Topics: Age Factors; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; C | 2008 |
[Treatment of hypertensive patients of 80 years of age or older].
Topics: Aged, 80 and over; Antihypertensive Agents; Humans; Hypertension; Indapamide; Perindopril; Randomize | 2008 |
Primary CNS lymphoma presenting as fever of unknown origin.
Topics: Antihypertensive Agents; Antineoplastic Agents; Antitubercular Agents; Aspirin; Brain Neoplasms; Cra | 2009 |
Controversy in treating the oldest old with hypertension: is the hypertension in the very elderly trial the final answer?
Topics: Aged, 80 and over; Antihypertensive Agents; Data Interpretation, Statistical; Female; Frail Elderly; | 2009 |
Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anthropometry; Blood Glucose; Cholesterol, HDL; Comorbidi | 2009 |
[Effect of antihypertensive drugs on some humoral parameters of endothelial function].
Topics: Aged; Antihypertensive Agents; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Drug Ther | 2009 |
Protection of patients with diabetes, with or without hypertension: implications of ADVANCE for clinical practice.
Topics: Blood Pressure; Diabetes Mellitus; Humans; Hypertension; Indapamide; Perindopril | 2009 |
Heart protection: a key target in the management of patients with diabetes.
Topics: Blood Pressure; Cardiovascular Diseases; Diabetes Complications; Humans; Hypertension; Indapamide; P | 2009 |
Recent trends in hypertension treatment: perspectives from animal studies.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Female; Hu | 2009 |
Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Femoral Artery; Hyperten | 2009 |
[Effective treatment of arterial hypertension in women reduces frequency of calls for medical aid due to emergency indications. Data from the AFINA study].
Topics: Aged; Antihypertensive Agents; Delayed-Action Preparations; Drug Therapy, Combination; Emergency Med | 2009 |
[Treatment of hypertension in patients older than 80 years].
Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure | 2009 |
How controlling of hypertension might matter.
Topics: Adiponectin; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Blood Gl | 2009 |
Effects of additional administration of low-dose indapamide on patients with hypertension treated with angiotensin II receptor blocker.
Topics: Age Factors; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; | 2010 |
[Comparative efficacy of a fixed combination perindopril/ indapamide in arterial hypertension patients of various sexes and ages].
Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P | 2010 |
[Diuretics in arterial hypertension: what is the basis of modern therapy].
Topics: Antihypertensive Agents; Carbohydrate Metabolism; Clinical Trials as Topic; Diuretics; Drug Therapy, | 2010 |
More than a REASON to use arterial stiffness as risk marker and therapeutic target in hypertension.
Topics: Antihypertensive Agents; Aorta; Atenolol; Blood Flow Velocity; Blood Pressure; Brachial Artery; Card | 2011 |
[Selection of rational combinations of indapamide with various of calcium antagonists in patients with arterial hypertension].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulat | 2011 |
[Blood pressure therapy - differential therapeutic solutions. Fixed combination improves prognosis of hypertensive patients].
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Humans; Hypertension; Indapami | 2011 |
[Correction of aldosterone level as marker of RAAS dysfunction in patients with arterial hypertension degree II-III and chronic kidney diseases].
Topics: Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In | 2011 |
Relationship between the change in left ventricular hypertrophy and asleep blood pressure after sodium restriction and/or diuretic treatment.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diet, Sodium-R | 2011 |
Efficacy and safety of treatment of hypertensive patients with fixed combination perindopril/indapamide up to 10/2.5 mg: results of the FALCO FORTE programme.
Topics: Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood | 2011 |
The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat.
Topics: Animals; Captopril; Collagen Type I; Collagen Type III; Fibrosis; Hypertension; Hypertrophy, Left Ve | 2011 |
[Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome].
Topics: Antihypertensive Agents; Comorbidity; Drug Administration Schedule; Drug Therapy, Combination; Femal | 2011 |
Antihypertensives in octogenarians.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Indapamide; Male; Perindopril; Severity of Il | 2012 |
[Nephroprotection diabetes mellitus type 2: lessons from the ADVANCE trial].
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combinatio | 2011 |
[The influence of vascular remodeling and endothelial vasomotor function on the efficacy of indapamide retard in patients with hypertensive disease].
Topics: Adult; Antihypertensive Agents; Endothelium, Vascular; Female; Humans; Hypertension; Indapamide; Mal | 2012 |
[Potentialities of medicinal correction of cerebrovascular disturbances in patients with arterial hypertension].
Topics: Amlodipine; Antihypertensive Agents; Bisoprolol; Cerebrovascular Disorders; Drug Therapy, Combinatio | 2012 |
[Vascular effects of perindopril arginine and indapamide fixed combination in patients with arterial hypertension].
Topics: Administration, Oral; Antihypertensive Agents; Arteries; Biological Availability; Blood Pressure; Dr | 2012 |
Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment.
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combinatio | 2002 |
[The challenge to treat hypertensive patients with type 2 diabetes].
Topics: Adult; Albuminuria; Antihypertensive Agents; Body Mass Index; Cardiovascular Diseases; Diabetes Mell | 2002 |
[Reflexion of French experts on the key points of the symposium].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; | 2002 |
Indapamide induced syncope in a patient with long QT syndrome.
Topics: Antihypertensive Agents; Electrocardiography; Female; Humans; Hypertension; Hypokalemia; Indapamide; | 2002 |
[Arterial hypertension and tachycardia: monitoring the patient's personal drug therapy].
Topics: Adult; Black People; Blood Pressure Monitoring, Ambulatory; Diagnosis, Differential; Drug Monitoring | 2002 |
[Clinical assessment of efficacy and safety of noliprel in patients with hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Humans; Hypertension; Indapamide; M | 2002 |
[Changes of distensibility of the aorta in elderly patients during long-term therapy with various classes of hypotensive drugs (magnetic resonance tomography data)].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors | 2002 |
Cardiovascular protective role of a low-dose antihypertensive combination in obese Zucker rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiova | 2003 |
Blood pressure-lowering for secondary prevention of stroke: ACE inhibition is not the key.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo | 2003 |
Blood pressure-lowering for secondary prevention of stroke: ACE inhibition is the key.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Blood | 2003 |
Blood pressure reduction and ACE inhibition in secondary stroke prevention: mechanism uncertain.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Clinical Trials a | 2003 |
[Management of dementia and cognitive functions in patients after cerebrovascular stroke: new results from the PROGRESS study].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cognition Disorders; Dementia; Humans; Hypertensio | 2003 |
Myocardial indium-111-antimyosin uptake in essential hypertension.
Topics: Aged; Antibodies, Monoclonal; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Indapam | 2003 |
[Americans demand stricter blood pressure control. Does 120/80 already need to be treated?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Diastole; Diur | 2003 |
[Relationship between changes of endothelial vasodilator function, vascular and cardiac structure and derangements of blood pressure 24-hour profile].
Topics: Angiotensin-Converting Enzyme Inhibitors; Brachial Artery; Circadian Rhythm; Diuretics; Echocardiogr | 2003 |
[Results of monotherapy with retard formulation of indapamide of elderly patients with isolated systolic hypertension and left ventricular hypertrophy].
Topics: Aged; Aged, 80 and over; Delayed-Action Preparations; Diuretics; Electrocardiography; Female; Humans | 2003 |
[Newly diagnosed hypertensive. It calls for treatment immediately with a combination ].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Diureti | 2003 |
Secondary prevention for stroke and transient ischaemic attacks.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypercholesterolemia; Hyp | 2004 |
Effects of indapamide, a thiazide-like diuretic, on structure of cerebral arterioles in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Brain; Diuretics; Dose-Response Relati | 2004 |
Left ventricular hypertrophy in hypertensive patients in Indian primary care: prevalence and effect of treatment with sustained release indapamide.
Topics: Antihypertensive Agents; Delayed-Action Preparations; Echocardiography; Electrocardiography; Female; | 2004 |
[Effect of fixed low dose combination of perindopril and indapamide on processes of cardiovascular remodeling in previously untreated patients with hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Carotid Intima-Media Thickness; Humans; Hypertension; Indap | 2004 |
Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports).
Topics: Adult; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus; Drug Therapy, Combination; Female; | 2004 |
[The benefit of a fixed combination of antihypertensives in hypertension treatment].
Topics: Antihypertensive Agents; Diuretics; Drug Combinations; Humans; Hypertension; Indapamide; Perindopril | 2004 |
[Clinical efficacy of noliprel in the treatment of hypertension. Main results of ETALON].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Data In | 2004 |
The PROGRESS trial three years later: time for a balanced report of effectiveness.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Data Interpretation, Statistical; | 2004 |
The PROGRESS trial three years later: time for more action, less distraction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Data Interpretation, Statistical; | 2004 |
The PROGRESS trial three years later: HOPE trial may shed some light.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Humans; Hypertension; Indapamide; Perindopril; R | 2004 |
[The drug of the month: a new antihypertensive association: Preterax, low doses of ACE inhibitor and thiazide in the same pill].
Topics: Drug Combinations; Humans; Hypertension; Indapamide; Perindopril; Remission Induction; Time Factors | 2004 |
[Effect of low dose combination of antihypertensive drugs on the state of microcirculation].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy | 2005 |
C-reactive protein elevation predicts pulse pressure reduction in hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitor | 2005 |
[Comparison of therapeutic strategies in the management of hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diuretics; Drug Therapy, Combinat | 2005 |
[Vascular impact of anti-hypertensive treatment and renal protection].
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diuretics; Double-Bl | 2005 |
What can be learned from the experience with the fixed low-dose combination of perindopril/indapamide in the treatment of hypertension?
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, T | 2005 |
QT interval prolongation and torsade de pointes associated with indapamide.
Topics: Adult; Diuretics; Electrocardiography; Female; Heart Conduction System; Humans; Hypertension; Indapa | 2006 |
The X-cellent Study.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihy | 2006 |
[Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension].
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Creatinine; Diuretics; Female; Follow-Up Studies; Hu | 2006 |
Concurrent dolichoectasia of basilar and coronary arteries.
Topics: Age of Onset; Aged; Aged, 80 and over; Antihypertensive Agents; Basilar Artery; Celiprolol; Coronary | 2006 |
[Comparative assessment of hypotensive, metabolic, and endothelial effects of indapamide-retard and hydrochlorothiazide in patients with essential hypertension].
Topics: Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brachial Artery; Endothelium, Vascular | 2006 |
[Cerebral and myocardial perfusion in patients with arterial hypertension and metabolic syndrome after monotherapy with combined drug noliprel].
Topics: Angiotensin-Converting Enzyme Inhibitors; Brain; Cerebrovascular Circulation; Coronary Circulation; | 2006 |
Letter by Safar and Fournier regarding article, "Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study".
Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Aorta; Atenolol; Blood Pressure; H | 2006 |
Chronic and acute effects of different antihypertensive drugs on femoral artery relaxation of L-NAME hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pre | 2007 |
Antihypertensive efficacy of indapamide SR in hypertensive patients uncontrolled with a background therapy: the NATIVE study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertensio | 2007 |
[Type 2 diabetes: blood pressure lowering to 135/75 mmHg reduces mortality].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics | 2007 |
[Antihypertensive therapy in diabetic patients. What do the new data mean for the practice?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus; Diuretics; Fam | 2007 |
New drug combo lowers blood pressure: all diabetics benefit. Two drugs offer lifesaving benefits, even in diabetes with normal blood pressure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetic Angiopathies; Diabetic R | 2007 |
Advances in reducing the burden of vascular disease in type 2 diabetes.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type | 2008 |
Combination of the angiotensin-converting enzyme inhibitor perindopril and the diuretic indapamide activate postnatal vasculogenesis in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, CD34; Antihypertensive Agents; Diuretic | 2008 |
Trials that matter: the effect of a fixed-dose combination of an Angiotensin-converting enzyme inhibitor and a diuretic on the complications of type 2 diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Diabete | 2008 |
Stroke secondary prevention and blood pressure reduction: an observational study of the use of PROGRESS therapy.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparations; Diureti | 2008 |
Antioxidative effects of melatonin administration in elderly primary essential hypertension patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Antioxidants; Catalase; Glutathione; Glutathione P | 2008 |
[Clinical assessment of metabolic effects of antihypertensive therapy].
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Gl | 2008 |
[Changes of elastic properties of peripheral vessels and parameters of endothelial function at the background of the use of fixed combination of perindopril and indapamide in patients with hypertensive disease].
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Brachial Artery; Diuretics; Dose-Response | 2008 |
[Type 2 diabetes. Routine ACE inhibitors?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug C | 2008 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
Treatment of mild hypertension and the problem of compliance.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Benzothiadiazines; Diuretics; Female; H | 1983 |
[Normokaliuretic hypokalemia during inadapamide treatment of hypertension].
Topics: Adult; Aged; Diuretics; Female; Humans; Hypertension; Hypokalemia; Indapamide; Male; Middle Aged; Po | 1984 |
[Mechanism of action of benzothiadiazides in arterial hypertension: the energetic theory].
Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorthalidone; Columbidae; Cyclic AMP; Diuretics; Energy Meta | 1982 |
Long-term effectiveness of indapamide in hypertension: neural, renin and metabolic responses.
Topics: Adult; Aged; Blood Pressure; Diuretics; Female; Follow-Up Studies; Heart Rate; Humans; Hyperglycemia | 1983 |
Correction of altered noradrenaline reactivity in essential hypertension by indapamide.
Topics: Adolescent; Adult; Aged; Angiotensin II; Diuretics; Dose-Response Relationship, Drug; Epinephrine; F | 1983 |
Blood pressure and diabetic control. Results of indapamide treatment.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diuretics; Female; Humans; Hypertension; Inda | 1984 |
Effect of indapamide on the renin-aldosterone system, and urinary excretion of potassium and calcium in essential hypertension.
Topics: Adult; Aldosterone; Calcium; Creatinine; Diuretics; Female; Humans; Hypertension; Indapamide; Male; | 1984 |
Once daily indapamide in the treatment of the elderly and young hypertensive.
Topics: Adolescent; Adult; Aged; Blood Pressure; Diuretics; Echocardiography; Female; Humans; Hypertension; | 1984 |
Effect of indapamide on renal plasma flow, glomerular filtration rate and arginine vasopressin in plasma in essential hypertension.
Topics: Adult; Arginine Vasopressin; Blood Pressure; Body Water; Diuretics; Female; Glomerular Filtration Ra | 1984 |
Indapamide. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension.
Topics: Antihypertensive Agents; Diuretics; Edema; Hemodynamics; Humans; Hypertension; Indapamide; Kidney; K | 1984 |
The influence of indapamide on serum lipoproteins in essential hypertension.
Topics: Adult; Cholesterol; Diuretics; Humans; Hypertension; Indapamide; Lipoproteins; Male; Middle Aged; Tr | 1984 |
Antihypertensive effect of indapamide with special emphasis on renal prostaglandin production.
Topics: Adult; Aged; Antihypertensive Agents; Dinoprost; Dinoprostone; Diuretics; Drug Therapy, Combination; | 1983 |
Different blood pressure responses to diuretic treatment in normotensive subjects with and without a family history of hypertension.
Topics: Adult; Blood Pressure; Chlorthalidone; Diuretics; Epinephrine; Female; Heart Rate; Humans; Hypertens | 1983 |
Drinking water and drug dosage in rat studies.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Bepridil; Blood Pressure; Dose-Response Re | 1983 |
A systemic hemodynamic evaluation of indapamide.
Topics: Adult; Blood Pressure; Diuretics; Echocardiography; Female; Hemodynamics; Humans; Hypertension; Inda | 1983 |
Effects of the acute and chronic administration of indapamide on systemic and renal haemodynamics in essential hypertension.
Topics: Adult; Blood Pressure; Diuretics; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperten | 1983 |
The place of indapamide in the treatment of arterial hypertension.
Topics: Diuresis; Diuretics; Dose-Response Relationship, Drug; Humans; Hypertension; Indapamide; Patient Com | 1983 |
Effect of indapamide on volume-dependent hypertension, renal haemodynamics, solute excretion and proximal nephron fractional reabsorption in the dog.
Topics: Animals; Blood Pressure; Chlorides; Diuretics; Dogs; Dose-Response Relationship, Drug; Electrolytes; | 1983 |
Indapamide: a unique diuretic?
Topics: Antihypertensive Agents; Diuretics; Edema; Humans; Hypertension; Indapamide | 1983 |
Once a day indapamide therapy in hypertension. Effects on the heart and peripheral arterial circulation.
Topics: Adult; Blood Circulation; Blood Glucose; Cholesterol; Diuretics; Drug Administration Schedule; Heart | 1983 |
[Initial values and drug effects].
Topics: Asthma; Bezafibrate; Blood Pressure Determination; Chlorthalidone; Cholesterol; Clenbuterol; Humans; | 1984 |
Indapamide and hypertension.
Topics: Diuretics; Humans; Hypertension; Indapamide | 1983 |
The antihypertensive effect of indapamide.
Topics: Aged; Blood Pressure; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Pulse; | 1983 |
Pharmacokinetics and clinical pharmacology of indapamide.
Topics: Animals; Calcium; Cats; Chemical Phenomena; Chemistry; Diuretics; Dose-Response Relationship, Drug; | 1983 |
[Effects on long-term treatment with indapamide in subjects with essential arterial hypertension].
Topics: Adult; Aged; Aldosterone; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Re | 1981 |
Relationship between plasma catecholamines and urinary catecholamine excretion rates in normal subjects and certain diseased states.
Topics: Adult; Blood Pressure; Chlorthalidone; Creatinine; Diabetes Mellitus; Electrolytes; Epinephrine; Fem | 1981 |
[Indapamide: more selectivity of action in hypertensive therapy].
Topics: Chemical Phenomena; Chemistry; Diuretics; Humans; Hypertension; Indapamide | 1982 |
[Antihypertensive and diuretic effects of indapamide in normotensive and hypertensive rats (author's transl)].
Topics: Animals; Carbonic Anhydrase Inhibitors; Desoxycorticosterone; Diuretics; Hypertension; In Vitro Tech | 1982 |
Indapamide in hypertension: a study in general practice of new or previously poorly controlled patients.
Topics: Aged; Aging; Blood Pressure; Diuretics; Humans; Hypertension; Indapamide; Time Factors | 1982 |
[Borderline or mild hypertension--a daily problem in medical practice (author's transl)].
Topics: Humans; Hypertension; Indapamide; Lipids; Muscle, Smooth; Risk; Ticrynafen | 1982 |
[Indapamide: its action in animals and man (author's transl)].
Topics: Animals; Blood Pressure; Cats; Diuretics; Dogs; Half-Life; Humans; Hypertension; Indapamide; Models, | 1982 |
[Studies of antihypertensional mechanism of indapamide (author's transl)].
Topics: Blood Pressure; Blood Volume; Body Weight; Diuretics; Humans; Hypertension; Indapamide | 1982 |
[Diuretic treatment and serum lipoproteins: effects of tienilic acid and indapamide (author's transl)].
Topics: Cholesterol; Cholesterol, LDL; Diuretics; Glycolates; Humans; Hypertension; Indapamide; Lipoproteins | 1982 |
[Clinical results of the combined use of a diuretic and a beta-blocking agent in the therapy of arterial hypertension].
Topics: Aged; Atenolol; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Inda | 1982 |
A multicenter study of indapamide in hypertensive patients with impaired renal function.
Topics: Adult; Aged; Blood Pressure; Body Weight; Creatinine; Diuretics; Female; Humans; Hypertension; Indap | 1982 |
[Long-term treatment of essential arterial hypertension with indapamide].
Topics: Adult; Aged; Diuretics; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Middle Aged | 1982 |
[Evaluation of the combination of atenolol and indapamide in the therapy of arterial hypertension (with data concerning toxicity and tolerance in the experimental animal)].
Topics: Adult; Aged; Animals; Atenolol; Blood Pressure; Body Weight; Diuretics; Dogs; Drug Therapy, Combinat | 1981 |
[Long term therapy of essential hypertension with indapamide: studies on the effect on electrolyte balance and glucose metabolism].
Topics: Adult; Aged; Blood Glucose; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; | 1980 |
Correction of altered noradrenaline reactivity in essential hypertension by indapamide.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Blood Volume; Diuretics; Female; Heart Rate; Huma | 1981 |
Non-invasive cardiovascular assessment of indapamide in patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Diuretics; Echocardiography; Female; Heart Function Tests; Heart Rat | 1981 |
Evaluation of the effect of indapamide on moderate benign essential hypertension complicated by airways obstruction.
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Female; Humans; Hypertension; Indapamide; Lung Dise | 1981 |
Continuous electrocardiographic recording (Holter method) during indapamide treatment: a study of 40 cases.
Topics: Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Diuretics; Electrocardiography; Female; | 1981 |
Blood sugar regulation during treatment with indapamide in hypertensive diabetics.
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diur | 1981 |
[Behavior of expiratory flow rate in hypertensive, chronic bronchitis patients during treatment with indapamide].
Topics: Bronchitis; Diuretics; Forced Expiratory Flow Rates; Humans; Hypertension; Indapamide; Peak Expirato | 1981 |
[Indapamide in the treatment of essential hypertension in the elderly: effect on glucose and lipid metabolism].
Topics: Blood Glucose; Diuretics; Humans; Hypertension; Indapamide; Lipids | 1981 |
[Evaluation of the efficacy of indapamide in the treatment of essential arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Mid | 1981 |
[Ambulatory treatment of hypertension].
Topics: Administration, Oral; Adolescent; Adult; Aged; Ambulatory Care; Blood Pressure; Diuretics; Female; H | 1980 |
[Drug information. Indapamide (Fludex)].
Topics: Diuretics; Humans; Hypertension; Indapamide | 1980 |
A Diuretic Specifically Designed for Treating Hypertension: Current Insights. Proceedings of a satellite symposium to the 14th scientific meeting of the International Society of Hypertension. Madrid, Spain, June 19, 1992.
Topics: Animals; Humans; Hypertension; Indapamide | 1993 |
Reactivity and sensitivity of the mesenteric artery in adult spontaneously hypertensive rats after chronic treatment with indapamide.
Topics: Animals; Blood Pressure; Heart Rate; Hemodynamics; Hypertension; Indapamide; Mesenteric Arteries; Ph | 1993 |
Comparative effects of indapamide and hydrochlorothiazide on cardiac hypertrophy and vascular smooth-muscle phenotype in the stroke-prone, spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Hydrochlorothiazide; Hypertension; Indapami | 1993 |
Oxygen radical scavengers and renal protection by indapamide diuretic in salt-induced hypertension of Dahl strain rats.
Topics: Animals; Antioxidants; Free Radical Scavengers; Free Radicals; Glomerular Filtration Rate; Hypertens | 1993 |
[Severe pancytopenia in old age after 12-month ACE inhibitor therapy].
Topics: Aged; Anemia, Aplastic; Angiotensin-Converting Enzyme Inhibitors; Erythrocyte Transfusion; Female; F | 1994 |
Carotid artery mechanical properties of Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Carotid Arteries; Compliance; Diet, Sodium-Restricted; Drug Resistance; Hyp | 1995 |
Erythema multiforme and angioedema with indapamide and sertraline.
Topics: 1-Naphthylamine; Angioedema; Antidepressive Agents; Depressive Disorder; Drug Eruptions; Drug Intera | 1994 |
Alteration of renal receptors for atrial natriuretic peptide and vasopressin in spontaneously hypertensive rats treated with antihypertensive diuretics.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Furosemide; Hypertension; Indapamide; Kidney; Male | 1994 |
[The effect of indapamide on phosphate metabolism in hypertensive patients].
Topics: Adult; Aged; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Phosphates | 1993 |
Indapamide inhibits endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Diphosp | 1993 |
[The influence of indapamide on 6-keto-PGF1 alpha, PGE2, and PGF2 alpha synthesis and plasma TXB2 levels in spontaneously hypertensive rats].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Dinoprost; Dinoprostone; Female; Hypertension; Indapam | 1993 |
Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Evaluation, Preclinical; Fibrosis; Hyd | 1993 |
Fixed-dose combination of perindopril with indapamide in spontaneously hypertensive rats: haemodynamic, biological and structural effects.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Carotid Arteries; | 1996 |
Effects of aerobic training on exaggerated blood pressure response to exercise in African-Americans with severe systemic hypertension treated with indapamide +/- verapamil +/- enalapril.
Topics: Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Combined Modality Therapy; Drug | 1997 |
Sodium, survival, and the mechanical properties of the carotid artery in stroke-prone hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Carotid Artery, Common; Cerebrovascular Disorders; Collagen; D | 1997 |
Acute hyponatremic encephalopathy after a cerebrovascular accident.
Topics: Aged; Amiloride; Benzothiadiazines; Central Nervous System; Cerebral Hemorrhage; Coma; Diuretics; En | 1998 |
The diuretic indapamide increases bone mass and decreases bone resorption in spontaneously hypertensive rats supplemented with sodium.
Topics: Absorptiometry, Photon; Animals; Antihypertensive Agents; Biomarkers; Bone Density; Bone Resorption; | 1998 |
[Efficacy and safety of indapamide 1.5 mg sustained release coated tablets in the therapy of arterial hypertension].
Topics: Antihypertensive Agents; Delayed-Action Preparations; Diuretics; Dose-Response Relationship, Drug; F | 1998 |
Indapamide improves flow-induced dilation in hypertensive rats with a high salt intake.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Diuretics; Extracellular Space; Hypertension; Indapami | 1998 |
Protective effects of delapril, indapamide and their combination on stroke occurrence and lifespan in salt-loaded stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Cerebrovascular Disorders; Diuretics | 1998 |
Thiazide-induced vasodilation in humans is mediated by potassium channel activation.
Topics: Antihypertensive Agents; Blood Pressure; Carrier Proteins; Dose-Response Relationship, Drug; Humans; | 1998 |
Fixed low-dose perindopril 2 mg/indapamide 0.625 mg combination in very elderly hypertensives.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; | 1999 |
Quantitative determination of indapamide in pharmaceuticals and urine by high-performance liquid chromatography with amperometric detection.
Topics: Adult; Chromatography, High Pressure Liquid; Diuretics; Female; Humans; Hydrogen-Ion Concentration; | 1999 |
Low dose indapamide plus perindopril combination effects on cardiovascular structure and function in genetic hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Drug Therapy, Combination; | 1999 |
The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Blood Pressure; Capil | 2000 |
Protective effects of delapril combined with indapamide or hydrochlorothiazide in spontaneously hypertensive stroke-prone rats: a comparative dose-response analysis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Diuretics; Dose-Resp | 2000 |
Effects of indapamide in rats with pressure overload left ventricular hypertrophy.
Topics: Animals; Antihypertensive Agents; Aortic Valve Stenosis; Biomarkers; Blood Pressure; Creatinine; Hea | 2000 |
[A prospective study of over 3,000 hypertensive patients shows: diuretic monotherapy decreases blood pressure significantly].
Topics: Blood Pressure; Delayed-Action Preparations; Diuretics; Humans; Hypertension; Indapamide; Prospectiv | 2000 |
[New fixed combination for therapy of hypertension. "Softener" and "stimulant" supplement each other].
Topics: Antihypertensive Agents; Drug Combinations; Humans; Hypertension; Indapamide; Perindopril | 2001 |
Ambulatory blood pressure profiles in patients treated with once-daily diltiazem extended-release or indapamide alone or in combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Dela | 2000 |
Pulse wave velocity as endpoint in large-scale intervention trial. The Complior study. Scientific, Quality Control, Coordination and Investigation Committees of the Complior Study.
Topics: Adult; Aged; Antihypertensive Agents; Arteries; Automation; Blood Pressure; Carotid Arteries; Diuret | 2001 |
Perindopril + indapamide: new preparation. Simple trick.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Top | 1999 |
Combination BP therapy cuts second stroke risk in half.
Topics: Angiotensin-Converting Enzyme Inhibitors; Diuretics; Double-Blind Method; Humans; Hypertension; Inda | 2001 |
[Management of essential arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents | 2000 |
Sodium intake, large artery stiffness, and proteoglycans in the spontaneously hypertensive rat.
Topics: Animals; Arteries; Collagen; Compliance; Diuretics; Elastin; Hemodynamics; Hyaluronic Acid; Hyperten | 2001 |
The lowering of blood pressure after stroke.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination; Huma | 2001 |
The lowering of blood pressure after stroke.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination; Fema | 2001 |
The lowering of blood pressure after stroke.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination; Huma | 2001 |
The lowering of blood pressure after stroke.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Causality; Diuretics; Drug Therapy, Combin | 2001 |
The lowering of blood pressure after stroke.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Drug Therapy, Combination; Huma | 2001 |
[Efficacy of a converting enzyme inhibitor in the prevention of recurrence of stroke].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; Drug T | 2001 |
[Clinical study of the month. Secondary prevention of cerebrovascular accident with perindopril: the PROGRESS study].
Topics: Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Diuretics; Humans; Hypertension; | 2001 |
Effects of combination of low doses of angiotensin-converting enzyme inhibitor and diuretics on renal function in spontaneously hypertensive rats: comparison between acute and chronic treatment.
Topics: Animals; Antihypertensive Agents; Diuresis; Diuretics; Dose-Response Relationship, Drug; Drug Combin | 2001 |
The effects of the addition of micronised fenofibrate on uric acid metabolism in patients receiving indapamide.
Topics: Adult; Aged; Antihypertensive Agents; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Drug Therapy | 2002 |
Changes in vascular reactivity in experimental hypertensive animals following treatment with indapamide.
Topics: Animals; Blood Pressure; Brain; Cats; Desoxycorticosterone; Diuretics; Hydrochlorothiazide; Hyperten | 1977 |
Indapamide and xipamide - two more diuretics.
Topics: Diuretics; Humans; Hypertension; Indapamide; Xipamide | 1979 |
The effects of long term oral treatment with indapamide on the development of DOCA-salt hypertension in rats: vascular reactivity studies.
Topics: Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Diuretics; Eating; Hypertension; Indapam | 1979 |
[Clinical evaluation of a new antihypertensive drug (Indapamide)].
Topics: Diuretics; Drug Evaluation; Humans; Hypertension; Indapamide | 1978 |
[Hypokalemia during treatment with indapamide. 3 cases].
Topics: Aged; Diuretics; Female; Humans; Hypertension; Hypokalemia; Indapamide | 1978 |
[Indapamide].
Topics: Aged; Diuretics; Humans; Hypertension; Hypokalemia; Indapamide | 1978 |
[Antihypertensive effect of indapamide].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Evaluation; Female; Humans; Hy | 1977 |
Studies on the marked antihypertensive properties of indapamide (SE 1520) in rats and cats [proceedings].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cats; Depression, Chemical; Diuretics; Hypertensio | 1976 |
[Measurement of peripheral resistances by recording of carotidogramme. Study of a vasopressive agent and an anti-hypertensive agent].
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Mid | 1976 |
Antihypertensive action of indapamide. Comparative studies in several experimental models.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Chlorthalidone; Diuretics; Dogs; | 1975 |
[The effect of indapamide on plasma prostaglandins in hypertensive patients].
Topics: Adult; Aged; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Prostaglandins | 1992 |
Posterior subcapsular cataract associated with indapamide therapy.
Topics: Adult; Cataract; Cataract Extraction; Humans; Hypertension; Indapamide; Lens Capsule, Crystalline; L | 1992 |
Regression of microalbuminuria in type II diabetic, hypertensive patients after long-term indapamide treatment.
Topics: Adult; Albuminuria; Blood Pressure; Diabetes Mellitus, Type 2; Glomerular Filtration Rate; Humans; H | 1991 |
Influence of diuretics on brachial artery diameter and distensibility in hypertensive patients.
Topics: Adult; Brachial Artery; Canrenoic Acid; Diuretics; Female; Hemodynamics; Humans; Hypertension; Indap | 1990 |
[Effect of indapamide preparations on myocardial contractility and hemodynamics in patients with hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Indapamide; Male; Middle A | 1990 |
Effects of indapamide on left ventricular mass and function in systemic hypertension with left ventricular hypertrophy.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Diuretics; Echocardiography; Female; Follow-Up Studies; H | 1990 |
A symposium: Indapamide and antihypertensive strategy. April 28, 1989, Barcelona, Spain. Proceedings.
Topics: Diuretics; Humans; Hypertension; Indapamide | 1990 |
Effects of indapamide on the mechanical properties of the arterial wall in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Blood Pressure; Cardiac Output; Carotid Arteries; Desoxycorticosterone; Diuretics; Elastici | 1990 |
Efficacy of antihypertensive treatment with indapamide in patients with noninsulin-dependent diabetes and persistent microalbuminuria.
Topics: Adult; Albuminuria; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies | 1990 |
Twenty-four-hour blood pressure monitoring and effects of indapamide.
Topics: Blood Pressure; Blood Pressure Monitors; Cardiac Output; Circadian Rhythm; Diuretics; Female; Heart | 1990 |
Hypertension and micro-albuminuria in diabetic patients taking indapamide.
Topics: Aged; Aged, 80 and over; Albuminuria; Blood Pressure; Diabetes Mellitus; Diuretics; Drug Evaluation; | 1989 |
Therapeutic monitoring of metipamide during antihypertensive therapy.
Topics: Adult; Aged; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diuretics; Female; Human | 1989 |
[Antihypertensive therapy using metipamide VUFB].
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Female; Hemodynamics; Humans; Hypertension; Indapam | 1989 |
[The effect of metipamide on levels of sodium and potassium in erythrocytes].
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Erythrocytes; Female; Humans; Hypertension; In Vitr | 1989 |
Quality of life--treatment of hypertension. The role of indapamide.
Topics: Benzothiadiazines; Diuretics; Humans; Hypertension; Indapamide; Quality of Life; Sodium Chloride Sym | 1989 |
Is indapamide (Natrilix) 2.5 mg a diuretic?
Topics: Benzothiadiazines; Diuretics; Humans; Hypertension; Indapamide; Plasma Volume; Sodium Chloride Sympo | 1989 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Di | 1988 |
Antihypertensive profile of cicletanine, a furopyridine derivative: comparison with captopril, indapamide and prazosin.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Cardiomegaly; Diuresis; Diuretic | 1988 |
Effect of indapamide on atrial natriuretic polypeptide receptor in spontaneously hypertensive rat kidney.
Topics: Animals; Atrial Natriuretic Factor; Diuretics; Hypertension; Indapamide; Rats; Rats, Inbred SHR; Rat | 1986 |
Antihypertensive therapy in diabetic patients. The use of indapamide.
Topics: Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics; Drug Evaluation; Glucose Tolera | 1988 |
Well-being, hypertension, and indapamide. Proceedings of the XVth international meeting. November 8, 1986, Rome, Italy.
Topics: Diuretics; Humans; Hypertension; Indapamide; Quality of Life | 1988 |
Effect of indapamide on an experimental model of cerebral ischemia in hypertensive rats.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug E | 1988 |
Effects of indapamide on the quality of life of hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Diuretics; Drug Evaluation; Female; Humans; Hypertension; Indapamide; M | 1988 |
Acute effect of indapamide on urine calcium excretion in nephrolithiasis and human essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Diuretics; Female; Heart Rate; Humans; Hypertension; Indapamide; Mal | 1988 |
Indapamide in the diabetic hypertensive.
Topics: Diabetic Angiopathies; Diuretics; Humans; Hypertension; Indapamide | 1988 |
Antihypertensive effect of indapamide given in conjunction with captopril in severe hypertension.
Topics: Blood Pressure; Captopril; Diuretics; Drug Administration Schedule; Drug Evaluation; Drug Therapy, C | 1986 |
[Diuretics in the treatment of hypertension. Is indapamide starting a new trend?].
Topics: Diuretics; Humans; Hypertension; Hypertension, Renal; Indapamide | 1986 |
Can an antihypertensive agent be both effective and improve the quality of life? A multicentre study with indapamide.
Topics: Aged; Blood Pressure; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Qualit | 1986 |
[The effect of short-term administration of metipamide in patients with hypertension who were evaluated by non-invasive examination of the cardiovascular system].
Topics: Adult; Blood Pressure; Diuretics; Echocardiography; Electrocardiography; Female; Humans; Hypertensio | 1986 |
Indapamide. Effects on apoprotein, lipoprotein, and glucoregulation in ambulatory diabetic patients.
Topics: Adult; Aged; Apoproteins; Blood Glucose; C-Peptide; Diabetic Angiopathies; Diuretics; Female; Glycat | 1986 |
[Antihypertensive effect of indapamide and its effect on extracellular and intracellular Na and K concentrations in red blood cells].
Topics: Diuretics; Erythrocytes; Extracellular Space; Female; Humans; Hypertension; Indapamide; Male; Middle | 1985 |
[Diuretic and antihypertensive activity of azosemide].
Topics: Body Weight; Diuresis; Edema; Humans; Hypertension; Indapamide; Kidney Failure, Chronic; Sulfanilami | 1985 |
Efficacy and safety of medium term indapamide treatment in hypertensive diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 2; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle | 1985 |