indapamide has been researched along with Heart Failure in 12 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare efficacy and safety of indapamide-furosemide combination against metolazone-furosemide combination in refractory heart failure patients." | 9.30 | Comparing the sodium excreting efficacy of furosemide and indapamide combination against furosemide and metolazone combination in congestive heart failure patients: A randomized control trial. ( Altaf, A; Jan, MU; Salahudin, M; Shah, H, 2019) |
| "To compare efficacy and safety of indapamide-furosemide combination against metolazone-furosemide combination in refractory heart failure patients." | 5.30 | Comparing the sodium excreting efficacy of furosemide and indapamide combination against furosemide and metolazone combination in congestive heart failure patients: A randomized control trial. ( Altaf, A; Jan, MU; Salahudin, M; Shah, H, 2019) |
| "the Hypertension in the Very Elderly Trial (HYVET) was a randomised placebo-controlled trial of indapamide slow release 1." | 5.17 | Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial. ( Beckett, N; Bulpitt, C; Burch, L; Fagard, R; Fletcher, A; Li, M; Narkiewicz, K; Nitsch, D; Peters, R; Poulter, R; Wang, N, 2013) |
| "To report blood pressure control in the Hypertension in the Very Elderly Trial, a placebo-controlled trial of hypertensive (systolic blood pressure (SBP) 160-199 mm Hg, diastolic blood pressure (DBP) <110 mm Hg) participants over the age of 80 years, given treatment in three steps: indapamide slow release 1." | 5.16 | Blood pressure control in the Hypertension in the Very Elderly Trial (HYVET). ( Banya, W; Beckett, NS; Bulpitt, CJ; Burch, LA; Fagard, R; Fletcher, AE; Gergova, V; Leonetti, G; Peters, R, 2012) |
| "5 mg of indapamide retard with or without addition of 2-4 mg of perindopril, 30% lowering of risk of development of fatal and nonfatal stroke (95% confidence interval [CI] -1 to 51, p=0." | 3.74 | [Arterial hypertension in persons older than 80 years: the problem can be successfully solved]. ( Batyraliev, TA; Fettser, DV; Ishlek, M; Preobrazhenskiĭ, DV; Sidorenko, BA, 2008) |
| "The authors of the article studied potential of various drug combinations (atenolol + enalapril + indapamide, and celanid + enalapril + indapamide) in complex treatment of patients with heart failure (HF) and supraventricular arrhythmias." | 3.73 | [Cardiac glycosides in complex treatment of patients with heart failure and supraventricular arrhythmias]. ( Kremnev, IuA; Podshibiakin, SE; Zamotaev, IuN, 2005) |
| "Hypertension is a major influence on the development of LVH." | 2.43 | Ventricular hypertrophy and hypertension: prognostic elements and implications for management. ( Devereux, RB; Krauser, DG, 2006) |
| "Hyperlipidemia is a widely acknowledged side effect of thiazide diuretic therapy, but it is often dismissed as a short-term effect of high-dose therapy." | 2.40 | Hyperlipidemia of diuretic therapy. ( Ames, R, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salahudin, M | 1 |
| Shah, H | 1 |
| Jan, MU | 1 |
| Altaf, A | 1 |
| Bogachev, RS | 1 |
| Rfeenkova, VS | 1 |
| Kober, DV | 1 |
| Kraĭtser, AP | 1 |
| Thomopoulos, C | 1 |
| Parati, G | 1 |
| Zanchetti, A | 1 |
| Preobrazhenskiĭ, DV | 1 |
| Sidorenko, BA | 1 |
| Batyraliev, TA | 1 |
| Fettser, DV | 1 |
| Ishlek, M | 1 |
| Bulpitt, CJ | 1 |
| Beckett, NS | 1 |
| Peters, R | 2 |
| Leonetti, G | 1 |
| Gergova, V | 1 |
| Fagard, R | 2 |
| Burch, LA | 1 |
| Banya, W | 1 |
| Fletcher, AE | 1 |
| Beckett, N | 1 |
| Poulter, R | 1 |
| Burch, L | 1 |
| Narkiewicz, K | 1 |
| Nitsch, D | 1 |
| Wang, N | 1 |
| Li, M | 1 |
| Fletcher, A | 1 |
| Bulpitt, C | 1 |
| Friesewinkel, O | 1 |
| Furrer, M | 1 |
| Hänggi, G | 1 |
| Rutschmann, A | 1 |
| Zamotaev, IuN | 1 |
| Kremnev, IuA | 1 |
| Podshibiakin, SE | 1 |
| Krauser, DG | 1 |
| Devereux, RB | 1 |
| Opie, LH | 1 |
| Herbinger, W | 1 |
| Ames, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Hypertension in the Very Elderly Trial (HYVET)[NCT00122811] | Phase 4 | 4,000 participants (Anticipated) | Interventional | 2000-11-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for indapamide and Heart Failure
| Article | Year |
|---|---|
Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2015 |
Ventricular hypertrophy and hypertension: prognostic elements and implications for management.
Topics: Adrenergic Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convert | 2006 |
Hyperlipidemia of diuretic therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cere | 1998 |
4 trials available for indapamide and Heart Failure
| Article | Year |
|---|---|
Comparing the sodium excreting efficacy of furosemide and indapamide combination against furosemide and metolazone combination in congestive heart failure patients: A randomized control trial.
Topics: Administration, Intravenous; Administration, Oral; Aged; Body Weight; Diuretics; Drug Therapy, Combi | 2019 |
Blood pressure control in the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Heart | 2012 |
Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.
Topics: Age Factors; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Ag | 2013 |
[Severe heart failure: treatment optimisation and monitoring using plasma NT-proBNP levels--an useful tool in clinical practice].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol | 2004 |
5 other studies available for indapamide and Heart Failure
| Article | Year |
|---|---|
[Clinical aspects of vaso-and cardioprotection in patients with primary and recurrent myocardial infarction].
Topics: Cardiotonic Agents; Coronary Angiography; Coronary Vessels; Drug Combinations; Endothelium-Dependent | 2014 |
[Arterial hypertension in persons older than 80 years: the problem can be successfully solved].
Topics: Age Factors; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; C | 2008 |
[Cardiac glycosides in complex treatment of patients with heart failure and supraventricular arrhythmias].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Atenolol; Blood Pressure; Ca | 2005 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
[Diuretics in the therapy of chronic cardiac insufficiency].
Topics: Acetazolamide; Amiloride; Diuretics; Drug Interactions; Ethacrynic Acid; Heart Failure; Humans; Inda | 1982 |