indapamide has been researched along with Fibrosis in 5 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis." | 7.77 | The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011) |
| "We studied the effect of thiazide-like diuretic--indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) and assessed the involvement of nitric oxide in this process." | 7.74 | Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. ( Babál, P; Janega, P; Jendeková, L; Kojsová, S; Pechánová, O, 2007) |
| "Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp)." | 7.71 | Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment. ( Bacchelli, B; Biagini, G; Contri, MB; Miselli, M; Pedrazzi, G; Taparelli, F, 2002) |
| "The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis." | 3.77 | The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011) |
| "We studied the effect of thiazide-like diuretic--indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) and assessed the involvement of nitric oxide in this process." | 3.74 | Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. ( Babál, P; Janega, P; Jendeková, L; Kojsová, S; Pechánová, O, 2007) |
| " We thus investigated the long-term effects of an angiotensin-converting enzyme (ACE) inhibitor (perindopril)/diuretic (indapamide) combination (per/ind) in the Zucker rat, a classical model of chronic renal failure associated with obesity, hyperlipidemia, and insulin resistance." | 3.72 | Long-term protection of obese Zucker rat kidneys from fibrosis and renal failure with an angiotensin-converting enzyme inhibitor/diuretic combination. ( Belair, MF; Chainey, A; Chevalier, J; Mandet, C; Michel, O; Myara, I; Plante, GE; Renaud, IM, 2004) |
| "Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp)." | 3.71 | Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment. ( Bacchelli, B; Biagini, G; Contri, MB; Miselli, M; Pedrazzi, G; Taparelli, F, 2002) |
| "The aim was to compare the effects of two diuretics, indapamide and hydrochlorothiazide, on cardiac hypertrophy in stroke prone spontaneously hypertensive rats (SHR-SP)." | 3.68 | Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat. ( Contard, F; Glukhova, M; Guez, D; Marotte, F; Narcisse, G; Rappaport, L; Samuel, JL; Schatz, C; Swynghedauw, B, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hlavačková, L | 1 |
| Vranková, S | 1 |
| Janega, P | 2 |
| Pecháňová, O | 2 |
| Babál, P | 2 |
| Contri, MB | 1 |
| Taparelli, F | 1 |
| Miselli, M | 1 |
| Pedrazzi, G | 1 |
| Bacchelli, B | 1 |
| Biagini, G | 1 |
| Renaud, IM | 1 |
| Chainey, A | 1 |
| Belair, MF | 1 |
| Mandet, C | 1 |
| Michel, O | 1 |
| Myara, I | 1 |
| Chevalier, J | 1 |
| Plante, GE | 1 |
| Kojsová, S | 1 |
| Jendeková, L | 1 |
| Contard, F | 1 |
| Glukhova, M | 1 |
| Marotte, F | 1 |
| Narcisse, G | 1 |
| Schatz, C | 1 |
| Swynghedauw, B | 1 |
| Guez, D | 1 |
| Samuel, JL | 1 |
| Rappaport, L | 1 |
5 other studies available for indapamide and Fibrosis
| Article | Year |
|---|---|
The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat.
Topics: Animals; Captopril; Collagen Type I; Collagen Type III; Fibrosis; Hypertension; Hypertrophy, Left Ve | 2011 |
Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment.
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combinatio | 2002 |
Long-term protection of obese Zucker rat kidneys from fibrosis and renal failure with an angiotensin-converting enzyme inhibitor/diuretic combination.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diuretics; Drug Combinations; Fibrosis; Indapamid | 2004 |
Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related.
Topics: Animals; Azo Compounds; Blood Pressure; Cardiomyopathies; Collagen Type I; Collagen Type III; Colori | 2007 |
Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Evaluation, Preclinical; Fibrosis; Hyd | 1993 |