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indapamide and Fibrosis

indapamide has been researched along with Fibrosis in 5 studies

Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis."7.77The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011)
"We studied the effect of thiazide-like diuretic--indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) and assessed the involvement of nitric oxide in this process."7.74Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. ( Babál, P; Janega, P; Jendeková, L; Kojsová, S; Pechánová, O, 2007)
"Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp)."7.71Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment. ( Bacchelli, B; Biagini, G; Contri, MB; Miselli, M; Pedrazzi, G; Taparelli, F, 2002)
"The aim of this study was to analyze the effect of indapamide and its combination with ACE inhibitor (captopril) and antioxidant (Provinols™) on both myocardial hypertrophy and fibrosis."3.77The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat. ( Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S, 2011)
"We studied the effect of thiazide-like diuretic--indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) and assessed the involvement of nitric oxide in this process."3.74Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. ( Babál, P; Janega, P; Jendeková, L; Kojsová, S; Pechánová, O, 2007)
" We thus investigated the long-term effects of an angiotensin-converting enzyme (ACE) inhibitor (perindopril)/diuretic (indapamide) combination (per/ind) in the Zucker rat, a classical model of chronic renal failure associated with obesity, hyperlipidemia, and insulin resistance."3.72Long-term protection of obese Zucker rat kidneys from fibrosis and renal failure with an angiotensin-converting enzyme inhibitor/diuretic combination. ( Belair, MF; Chainey, A; Chevalier, J; Mandet, C; Michel, O; Myara, I; Plante, GE; Renaud, IM, 2004)
"Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp)."3.71Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment. ( Bacchelli, B; Biagini, G; Contri, MB; Miselli, M; Pedrazzi, G; Taparelli, F, 2002)
"The aim was to compare the effects of two diuretics, indapamide and hydrochlorothiazide, on cardiac hypertrophy in stroke prone spontaneously hypertensive rats (SHR-SP)."3.68Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat. ( Contard, F; Glukhova, M; Guez, D; Marotte, F; Narcisse, G; Rappaport, L; Samuel, JL; Schatz, C; Swynghedauw, B, 1993)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hlavačková, L1
Vranková, S1
Janega, P2
Pecháňová, O2
Babál, P2
Contri, MB1
Taparelli, F1
Miselli, M1
Pedrazzi, G1
Bacchelli, B1
Biagini, G1
Renaud, IM1
Chainey, A1
Belair, MF1
Mandet, C1
Michel, O1
Myara, I1
Chevalier, J1
Plante, GE1
Kojsová, S1
Jendeková, L1
Contard, F1
Glukhova, M1
Marotte, F1
Narcisse, G1
Schatz, C1
Swynghedauw, B1
Guez, D1
Samuel, JL1
Rappaport, L1

Other Studies

5 other studies available for indapamide and Fibrosis

ArticleYear
The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat.
    Physiological research, 2011, Volume: 60, Issue:6

    Topics: Animals; Captopril; Collagen Type I; Collagen Type III; Fibrosis; Hypertension; Hypertrophy, Left Ve

2011
Dose-dependent prevention of fibrosis in aorta of salt-loaded stroke-prone spontaneously hypertensive rats by combined delapril and indapamide treatment.
    Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:3

    Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combinatio

2002
Long-term protection of obese Zucker rat kidneys from fibrosis and renal failure with an angiotensin-converting enzyme inhibitor/diuretic combination.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diuretics; Drug Combinations; Fibrosis; Indapamid

2004
Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related.
    Physiological research, 2007, Volume: 56, Issue:6

    Topics: Animals; Azo Compounds; Blood Pressure; Cardiomyopathies; Collagen Type I; Collagen Type III; Colori

2007
Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat.
    Cardiovascular research, 1993, Volume: 27, Issue:3

    Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Evaluation, Preclinical; Fibrosis; Hyd

1993