indapamide has been researched along with Essential Hypertension in 13 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Essential Hypertension: Hypertension that occurs without known cause, or preexisting renal disease. Associated polymorphisms for a number of genes have been identified, including AGT, GNB3, and ECE1. OMIM: 145500
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this non-interventional post-marketing clinical trial was to analyze the antihypertensive effect and safety of a fixed combination of perindopril and indapamide in the treatment of unregulated essential hypertension." | 9.51 | The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study. ( Boloban, A; Džananović Jaganjac, J; Glamočlija, U; Mehić, M; Popović, Ž; Šukalo, A; Tanović Avdić, A; Tirić Čampara, M, 2022) |
| "We investigated changes in blood pressure (BP) and metabolic adverse effects, especially elevation of uric acid (UA), after treatment with a thiazide-like diuretic (TD) in patients with essential hypertension." | 9.34 | Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension. ( Hanada, H; Higaki, J; Higashiura, K; Horio, T; Hosomi, N; Igase, M; Ishimitsu, T; Iwashima, Y; Kamide, K; Katabuchi, R; Kato, J; Kawano, Y; Kojima, S; Komai, N; Matsuura, H; Miki, T; Miwa, Y; Miyata, T; Morimoto, S; Nakahama, H; Nakahashi, T; Nakamura, S; Ohta, Y; Oukura, T; Rakugi, H; Sasaguri, T; Sase, K; Shimamoto, K; Shinagawa, T; Soma, M; Sugimoto, K; Takeda, K; Takiuchi, S; Tomohiro Katsuya, T; Tsuchihashi, T; Ueno, M; Yoshihara, F, 2020) |
| " The EFFICIENT study examines the efficacy and acceptability of a single-pill combination of sustained-release (SR) indapamide, a thiazide-like diuretic, and amlodipine, a calcium channel blocker (CCB), in the management of hypertension." | 9.19 | Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study. ( Gujral, VK; Hiremath, J; Jadhav, U; Namjoshi, DJ; Safar, M; Shamanna, P; Siraj, M; Tripathi, KK, 2014) |
| " Both treatment regimens were well tolerated regarding adverse events or laboratory testing." | 6.84 | Blood pressure-lowering efficacy and safety of perindopril/indapamide/amlodipine single-pill combination in patients with uncontrolled essential hypertension: a multicenter, randomized, double-blind, controlled trial. ( Amodeo, C; Asmar, R; Brzozowska-Villatte, R; de Champvallins, M; Mourad, JJ, 2017) |
| "The objective of this non-interventional post-marketing clinical trial was to analyze the antihypertensive effect and safety of a fixed combination of perindopril and indapamide in the treatment of unregulated essential hypertension." | 5.51 | The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study. ( Boloban, A; Džananović Jaganjac, J; Glamočlija, U; Mehić, M; Popović, Ž; Šukalo, A; Tanović Avdić, A; Tirić Čampara, M, 2022) |
| "We investigated changes in blood pressure (BP) and metabolic adverse effects, especially elevation of uric acid (UA), after treatment with a thiazide-like diuretic (TD) in patients with essential hypertension." | 5.34 | Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension. ( Hanada, H; Higaki, J; Higashiura, K; Horio, T; Hosomi, N; Igase, M; Ishimitsu, T; Iwashima, Y; Kamide, K; Katabuchi, R; Kato, J; Kawano, Y; Kojima, S; Komai, N; Matsuura, H; Miki, T; Miwa, Y; Miyata, T; Morimoto, S; Nakahama, H; Nakahashi, T; Nakamura, S; Ohta, Y; Oukura, T; Rakugi, H; Sasaguri, T; Sase, K; Shimamoto, K; Shinagawa, T; Soma, M; Sugimoto, K; Takeda, K; Takiuchi, S; Tomohiro Katsuya, T; Tsuchihashi, T; Ueno, M; Yoshihara, F, 2020) |
| " The EFFICIENT study examines the efficacy and acceptability of a single-pill combination of sustained-release (SR) indapamide, a thiazide-like diuretic, and amlodipine, a calcium channel blocker (CCB), in the management of hypertension." | 5.19 | Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study. ( Gujral, VK; Hiremath, J; Jadhav, U; Namjoshi, DJ; Safar, M; Shamanna, P; Siraj, M; Tripathi, KK, 2014) |
| "Our aim was to compare changes of vascular and metabolic parameters in patients with essential hypertension on treatment with combination of perindopril with either indapamide retard or hydrochlorothiazide." | 5.19 | [Direct comparison of endothelial and metabolic effects of perindopril combination with indapamide retard or hydrochlorothiazide]. ( Chindareva, OI; Nechaeva, GI; Pritykina, TV; Semenkin, AA; Stroeva, TV; Zhenatov, AB; Zhivilova, LA, 2014) |
| "Long-term treatment of patients with essential hypertension (EH) and autonomic dysfunction (sympathicotonia type) with lisinopril in combination with indapamide augmented activity of humoral systems and improved heart rate variability." | 3.79 | [Optimization of pharmacotherapy in patients with essential hypertension with neurohumoral modulators with consideration of data on heart rate variability]. ( Bakhshaliev, AB; Kakhramanova, SM, 2013) |
| " Both treatment regimens were well tolerated regarding adverse events or laboratory testing." | 2.84 | Blood pressure-lowering efficacy and safety of perindopril/indapamide/amlodipine single-pill combination in patients with uncontrolled essential hypertension: a multicenter, randomized, double-blind, controlled trial. ( Amodeo, C; Asmar, R; Brzozowska-Villatte, R; de Champvallins, M; Mourad, JJ, 2017) |
| "Hypertension is a modifiable cardiovascular risk factor." | 2.50 | Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension. ( Bassett, K; Musini, VM; Nazer, M; Wright, JM, 2014) |
| "Treatment with amlodipine, candesartan, or indapamide did not significantly affect plasma visfatin levels." | 1.43 | Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations. ( Piecha, G; Skoczylas, A; Więcek, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Šukalo, A | 1 |
| Džananović Jaganjac, J | 1 |
| Tanović Avdić, A | 1 |
| Glamočlija, U | 1 |
| Popović, Ž | 1 |
| Boloban, A | 1 |
| Tirić Čampara, M | 1 |
| Mehić, M | 1 |
| Ohta, Y | 1 |
| Kamide, K | 1 |
| Hanada, H | 1 |
| Morimoto, S | 1 |
| Nakahashi, T | 1 |
| Takiuchi, S | 1 |
| Ishimitsu, T | 1 |
| Tsuchihashi, T | 1 |
| Soma, M | 1 |
| Tomohiro Katsuya, T | 1 |
| Sugimoto, K | 1 |
| Rakugi, H | 1 |
| Oukura, T | 1 |
| Higaki, J | 1 |
| Matsuura, H | 1 |
| Shinagawa, T | 1 |
| Miwa, Y | 1 |
| Sasaguri, T | 1 |
| Igase, M | 1 |
| Miki, T | 1 |
| Takeda, K | 1 |
| Higashiura, K | 1 |
| Shimamoto, K | 1 |
| Katabuchi, R | 1 |
| Ueno, M | 1 |
| Hosomi, N | 1 |
| Kato, J | 1 |
| Komai, N | 1 |
| Kojima, S | 1 |
| Sase, K | 1 |
| Iwashima, Y | 1 |
| Yoshihara, F | 1 |
| Horio, T | 1 |
| Nakamura, S | 1 |
| Nakahama, H | 1 |
| Miyata, T | 1 |
| Kawano, Y | 1 |
| Ostroumova, TM | 1 |
| Ostroumova, OD | 1 |
| Parfenov, VA | 1 |
| Perepelova, EM | 1 |
| Perepelov, VA | 1 |
| Kochetkov, AI | 1 |
| Li, DQ | 1 |
| Choudhry, N | 1 |
| Dominiczak, AF | 1 |
| de Champvallins, M | 2 |
| Brzozowska-Villatte, R | 2 |
| Asmar, R | 2 |
| Jadhav, U | 1 |
| Hiremath, J | 1 |
| Namjoshi, DJ | 1 |
| Gujral, VK | 1 |
| Tripathi, KK | 1 |
| Siraj, M | 1 |
| Shamanna, P | 1 |
| Safar, M | 1 |
| Kakhramanova, SM | 1 |
| Bakhshaliev, AB | 1 |
| Musini, VM | 1 |
| Nazer, M | 1 |
| Bassett, K | 1 |
| Wright, JM | 1 |
| Semenkin, AA | 1 |
| Zhenatov, AB | 1 |
| Zhivilova, LA | 1 |
| Nechaeva, GI | 1 |
| Pritykina, TV | 1 |
| Chindareva, OI | 1 |
| Stroeva, TV | 1 |
| Skoczylas, A | 1 |
| Piecha, G | 1 |
| Więcek, A | 1 |
| Nádházi, Z | 1 |
| Dézsi, CA | 1 |
| Zheleznyh, EA | 1 |
| Danilogorskaya, YA | 1 |
| Privalova, EV | 1 |
| Belenkov, YN | 1 |
| Schendrygina, AA | 1 |
| Pavlov, NA | 1 |
| Tishman, MI | 1 |
| Mourad, JJ | 1 |
| Amodeo, C | 1 |
2 reviews available for indapamide and Essential Hypertension
| Article | Year |
|---|---|
Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Essential Hypertension; Humans; Hydr | 2014 |
The Results of ACES (Antihypertensive Combinations' Long Term Efficacy Comparing Study): Analysis of Metabolic Effects of Antihypertensive Combination Therapies.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel | 2016 |
7 trials available for indapamide and Essential Hypertension
| Article | Year |
|---|---|
The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study.
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Humans; Hyperten | 2022 |
Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Cross- | 2020 |
Effect of Perindopril/Indapamide on Cerebral Blood Flow in Middle-Aged, Treatment-Naïve Patients with Hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cerebro | 2020 |
Efficacy of a new single-pill combination of a thiazide-like diuretic and a calcium channel blocker (indapamide sustained release/amlodipine) in essential hypertension.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; B | 2019 |
Blood pressure control with a single-pill combination of indapamide sustained-release and amlodipine in patients with hypertension: the EFFICIENT study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Drug Combin | 2014 |
[Direct comparison of endothelial and metabolic effects of perindopril combination with indapamide retard or hydrochlorothiazide].
Topics: Aged; Antihypertensive Agents; Biological Availability; Blood Pressure; Carbohydrate Metabolism; Del | 2014 |
Blood pressure-lowering efficacy and safety of perindopril/indapamide/amlodipine single-pill combination in patients with uncontrolled essential hypertension: a multicenter, randomized, double-blind, controlled trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulat | 2017 |
4 other studies available for indapamide and Essential Hypertension
| Article | Year |
|---|---|
Coversyl-Induced Transient Serous Choroidal Detachments.
Topics: Aged; Antihypertensive Agents; Choroid Diseases; Drug Combinations; Essential Hypertension; Humans; | 2018 |
[Optimization of pharmacotherapy in patients with essential hypertension with neurohumoral modulators with consideration of data on heart rate variability].
Topics: Adult; Antihypertensive Agents; Cardiovascular Agents; Data Interpretation, Statistical; Drug Monito | 2013 |
Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; | 2016 |
[Effect of Combined Antihypertensive Therapy With Perindopril and Indapamide on Morpho-Functional Parameters of The Heart, Blood Vessels of Small and Medium Caliber in Patients With Essential Hypertension].
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Echocardiography; Essential Hypertension; | 2016 |