indapamide has been researched along with Electrolytes in 19 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg indapamide was compared in patients with essential hypertension, known as responders to diuretic therapy." | 9.06 | Comparative study on the antihypertensive efficacy of torasemide and indapamide in patients with essential hypertension. ( Achhammer, I; Glocke, M; Metz, P; Spannbrucker, N, 1988) |
| "A double-blind trial was carried out in 24 patients with mild hypertension to compare the efficacy and tolerability of indapamide with that of a standard thiazide diuretic, hydrochlorothiazide." | 9.05 | Indapamide in the treatment of essential arterial hypertension: results of a controlled study. ( Plante, GE; Robillard, C, 1983) |
| "1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 9.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 8.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "The aim of this study is to evaluate patients' demographics, patterns of presentation and outcomes of admissions with severe hyponatremia and other electrolyte disturbances that are related to indapamide." | 7.77 | Severe hyponatremia and other electrolyte disturbances associated with indapamide. ( Huang, JE; Lau, SY; Li, JY; Yong, TY, 2011) |
| "Since hypertension is an important risk factor of cardiovascular morbidity and mortality that can be at least in part decreased by pharmacologic reduction in elevated blood pressure, it is necessary that an antihypertensive agent be effective, but at the same time well tolerated and, according to some recent hypotheses, have no deleterious effect on serum electrolyte levels, as well as lipoprotein and glucose tolerance." | 6.66 | Tolerability and well-being with indapamide in the treatment of mild-moderate hypertension. An Italian multicenter study. ( Leonetti, G; Rappelli, A; Salvetti, A; Scapellato, L, 1988) |
| "Indapamide is a useful antihypertensive agent with good patient tolerance in mild or moderate hypertension and may offer advantages over traditional diuretics in view of its possible vasodilator and calcium-antagonist properties, once-a-day dosage, and good therapeutic effect with prolonged usage." | 6.65 | Clinical efficacy and safety of indapamide in essential hypertension. ( Morledge, JH, 1983) |
| "Indapamide was given in doses of 2." | 5.27 | Clinical efficacy and safety of indapamide in the treatment of edema. ( Slotkoff, L, 1983) |
| "5 mg indapamide was compared in patients with essential hypertension, known as responders to diuretic therapy." | 5.06 | Comparative study on the antihypertensive efficacy of torasemide and indapamide in patients with essential hypertension. ( Achhammer, I; Glocke, M; Metz, P; Spannbrucker, N, 1988) |
| "A double-blind trial was carried out in 24 patients with mild hypertension to compare the efficacy and tolerability of indapamide with that of a standard thiazide diuretic, hydrochlorothiazide." | 5.05 | Indapamide in the treatment of essential arterial hypertension: results of a controlled study. ( Plante, GE; Robillard, C, 1983) |
| "1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 5.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 4.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "Black women with established essential hypertension, without renal insufficiency or diabetes mellitus, were withdrawn from their usual antihypertensive therapy for 2-3 weeks prior to entry into a study to evaluate pertinent biochemical and mineral effects of indapamide treatment." | 4.78 | Biochemical, endocrine, and mineral effects of indapamide in black women. ( Beall, SP; Carr, AA; Feldman, DS; Feldman, EB; Hames, CG; Nichoalds, GE; Prisant, LM, 1990) |
| "The aim of this study is to evaluate patients' demographics, patterns of presentation and outcomes of admissions with severe hyponatremia and other electrolyte disturbances that are related to indapamide." | 3.77 | Severe hyponatremia and other electrolyte disturbances associated with indapamide. ( Huang, JE; Lau, SY; Li, JY; Yong, TY, 2011) |
| "Indapamide is a new antihypertensive diuretic agent indicated for the treatment of hypertension and edema." | 3.66 | Pharmacokinetics and clinical pharmacology of indapamide. ( Caruso, FS; Szabadi, RR; Vukovich, RA, 1983) |
| "Since hypertension is an important risk factor of cardiovascular morbidity and mortality that can be at least in part decreased by pharmacologic reduction in elevated blood pressure, it is necessary that an antihypertensive agent be effective, but at the same time well tolerated and, according to some recent hypotheses, have no deleterious effect on serum electrolyte levels, as well as lipoprotein and glucose tolerance." | 2.66 | Tolerability and well-being with indapamide in the treatment of mild-moderate hypertension. An Italian multicenter study. ( Leonetti, G; Rappelli, A; Salvetti, A; Scapellato, L, 1988) |
| "Indapamide is a useful antihypertensive agent with good patient tolerance in mild or moderate hypertension and may offer advantages over traditional diuretics in view of its possible vasodilator and calcium-antagonist properties, once-a-day dosage, and good therapeutic effect with prolonged usage." | 2.65 | Clinical efficacy and safety of indapamide in essential hypertension. ( Morledge, JH, 1983) |
| "Indapamide does not increase magnesium excretion when given in single doses to normal volunteers." | 2.36 | Indapamide: a review. ( Leary, WP; Reyes, AJ, 1983) |
| "Indapamide is a sulfonamide diuretic with vasodilative and calcium antagonistic effects, which enhances sodium delivery to the renal distal tubules resulting in a dose-related increase in urinary potassium excretion and decreases serum potassium concentrations." | 1.91 | [Intraoperative management of potentially fatal arrhythmias after anesthesia induced by severe hypokalemia: A case report]. ( Guo, XY; Wang, JC; Yao, YX, 2023) |
| "5 mg/kg/day) combined with indapamide (0." | 1.31 | Protective effects of delapril combined with indapamide or hydrochlorothiazide in spontaneously hypertensive stroke-prone rats: a comparative dose-response analysis. ( Agnati, LF; Biagini, G; Boschi, S; Torri, C; Vantaggiato, G; Zini, I; Zoli, M, 2000) |
| "Indapamide was given in doses of 2." | 1.27 | Clinical efficacy and safety of indapamide in the treatment of edema. ( Slotkoff, L, 1983) |
| "Renal hypertrophy was also decreased significantly by cicletanine at a dose of 100 mg/kg." | 1.27 | Comparison of cicletanine with other antihypertensive drugs in SHR-SP models. ( Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (73.68) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, JC | 1 |
| Yao, YX | 1 |
| Guo, XY | 1 |
| Roush, GC | 1 |
| Abdelfattah, R | 1 |
| Song, S | 1 |
| Kostis, JB | 1 |
| Ernst, ME | 1 |
| Sica, DA | 1 |
| Yong, TY | 1 |
| Huang, JE | 1 |
| Lau, SY | 1 |
| Li, JY | 1 |
| Morledge, JH | 1 |
| Plante, GE | 1 |
| Robillard, C | 1 |
| Reyes, AJ | 2 |
| Leary, WP | 2 |
| Burke, TJ | 1 |
| Nobles, EM | 1 |
| Wolf, PS | 1 |
| Erickson, AL | 1 |
| Van der Byl, K | 1 |
| Caruso, FS | 1 |
| Szabadi, RR | 1 |
| Vukovich, RA | 1 |
| Slotkoff, L | 1 |
| Schiffl, H | 1 |
| Weidmann, P | 1 |
| Meier, A | 1 |
| Ziegler, WH | 1 |
| Bing, RF | 1 |
| Russell, GI | 1 |
| Swales, JD | 1 |
| Thurston, H | 1 |
| Anania, V | 2 |
| Bartoli, E | 1 |
| Desole, MS | 2 |
| Faedda, R | 1 |
| Miele, E | 1 |
| Olmeo, NA | 1 |
| Satta, A | 1 |
| Soggia, G | 1 |
| Vacca, R | 1 |
| Boschi, S | 1 |
| Vantaggiato, G | 1 |
| Torri, C | 1 |
| Zini, I | 1 |
| Agnati, LF | 1 |
| Zoli, M | 1 |
| Biagini, G | 1 |
| Prisant, LM | 1 |
| Beall, SP | 1 |
| Nichoalds, GE | 1 |
| Feldman, EB | 1 |
| Carr, AA | 1 |
| Feldman, DS | 1 |
| Hames, CG | 1 |
| Malherbe, E | 1 |
| Le Hegarat, M | 1 |
| Clostre, F | 1 |
| Braquet, P | 1 |
| Leonetti, G | 1 |
| Rappelli, A | 1 |
| Salvetti, A | 1 |
| Scapellato, L | 1 |
| Spannbrucker, N | 1 |
| Achhammer, I | 1 |
| Metz, P | 1 |
| Glocke, M | 1 |
| Sanna, P | 1 |
| Cignarella, G | 1 |
| Siri, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for indapamide and Electrolytes
| Article | Year |
|---|---|
Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Diuretics, Potassium Spari | 2018 |
Indapamide: a review.
Topics: Aged; Arrhythmias, Cardiac; Blood Glucose; Blood Pressure; Diuretics; Electrolytes; Humans; Hyperten | 1983 |
Biochemical, endocrine, and mineral effects of indapamide in black women.
Topics: Adult; Black People; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hypertension; Indapami | 1990 |
6 trials available for indapamide and Electrolytes
| Article | Year |
|---|---|
Clinical efficacy and safety of indapamide in essential hypertension.
Topics: Adult; Aged; Animals; Clinical Trials as Topic; Diuretics; Double-Blind Method; Electrolytes; Humans | 1983 |
Indapamide in the treatment of essential arterial hypertension: results of a controlled study.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Electrolytes; Femal | 1983 |
Urinary magnesium output after a single dose of indapamide in healthy adults.
Topics: Adolescent; Adult; Diuretics; Electrolytes; Humans; Indapamide; Magnesium; Male; Time Factors | 1983 |
Indapamide and bendrofluazide: a comparison in the management of essential hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Diuretics; Electrolytes; Female; Humans; Hy | 1981 |
Tolerability and well-being with indapamide in the treatment of mild-moderate hypertension. An Italian multicenter study.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Tolerance; Ele | 1988 |
Comparative study on the antihypertensive efficacy of torasemide and indapamide in patients with essential hypertension.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Creatinine; Diuretics; Double- | 1988 |
10 other studies available for indapamide and Electrolytes
| Article | Year |
|---|---|
[Intraoperative management of potentially fatal arrhythmias after anesthesia induced by severe hypokalemia: A case report].
Topics: Aged; Anesthesia, General; Arrhythmias, Cardiac; Diuretics; Electrolytes; Humans; Hypokalemia; Indap | 2023 |
Severe hyponatremia and other electrolyte disturbances associated with indapamide.
Topics: Aged; Aged, 80 and over; Diuretics; Electrocardiography; Electrolytes; Female; Hospitals, Teaching; | 2011 |
Effect of indapamide on volume-dependent hypertension, renal haemodynamics, solute excretion and proximal nephron fractional reabsorption in the dog.
Topics: Animals; Blood Pressure; Chlorides; Diuretics; Dogs; Dose-Response Relationship, Drug; Electrolytes; | 1983 |
Pharmacokinetics and clinical pharmacology of indapamide.
Topics: Animals; Calcium; Cats; Chemical Phenomena; Chemistry; Diuretics; Dose-Response Relationship, Drug; | 1983 |
Clinical efficacy and safety of indapamide in the treatment of edema.
Topics: Body Weight; Diuretics; Double-Blind Method; Edema; Electrolytes; Female; Humans; Hydrochlorothiazid | 1983 |
Relationship between plasma catecholamines and urinary catecholamine excretion rates in normal subjects and certain diseased states.
Topics: Adult; Blood Pressure; Chlorthalidone; Creatinine; Diabetes Mellitus; Electrolytes; Epinephrine; Fem | 1981 |
[Evaluation of the combination of atenolol and indapamide in the therapy of arterial hypertension (with data concerning toxicity and tolerance in the experimental animal)].
Topics: Adult; Aged; Animals; Atenolol; Blood Pressure; Body Weight; Diuretics; Dogs; Drug Therapy, Combinat | 1981 |
Protective effects of delapril combined with indapamide or hydrochlorothiazide in spontaneously hypertensive stroke-prone rats: a comparative dose-response analysis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Diuretics; Dose-Resp | 2000 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Di | 1988 |
Diuretic agents related to indapamide. II. Synthesis and pharmacological activity of 1-alkyl, 1-carboxyalkyl- and 1,3-dialkyl substituted 2-(4-chloro-3-sulfamoylbenzamido)isoindolines.
Topics: Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Diuresis; Diuretics; Electrolytes; | 1985 |