Page last updated: 2024-10-29

indapamide and Disease Models, Animal

indapamide has been researched along with Disease Models, Animal in 10 studies

Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"In patients with arterial hypertension and left ventricular hypertrophy, perindopril + indapamide reduced blood pressure and left ventricular mass index and improved resting and hyperaemic myocardial blood flow."9.15Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension. ( Camici, PG; D'amati, G; Donato, L; Fommei, E; Ghione, S; Lombardi, M; Mancini, M; Neglia, D; Parker, H; Pisani, P; Varela-Carver, A, 2011)
"The fixed low-dose combination of the ACE inhibitor perindopril and the non-thiazide diuretic indapamide has been evaluated in the management of patients with mild to moderate hypertension."8.81Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. ( Cheer, SM; Goa, KL; Matheson, AJ, 2001)
"In patients with arterial hypertension and left ventricular hypertrophy, perindopril + indapamide reduced blood pressure and left ventricular mass index and improved resting and hyperaemic myocardial blood flow."5.15Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension. ( Camici, PG; D'amati, G; Donato, L; Fommei, E; Ghione, S; Lombardi, M; Mancini, M; Neglia, D; Parker, H; Pisani, P; Varela-Carver, A, 2011)
"The fixed low-dose combination of the ACE inhibitor perindopril and the non-thiazide diuretic indapamide has been evaluated in the management of patients with mild to moderate hypertension."4.81Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. ( Cheer, SM; Goa, KL; Matheson, AJ, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Brown, D1
Moezzi, D1
Dong, Y1
Koch, M1
Yong, VW1
Simko, F1
Pechanova, O2
Neglia, D1
Fommei, E1
Varela-Carver, A1
Mancini, M1
Ghione, S1
Lombardi, M1
Pisani, P1
Parker, H1
D'amati, G1
Donato, L1
Camici, PG1
Sládková, M1
Kojsová, S1
Jendeková, L1
Lebrillant, E1
Roulet, MJ1
Robert, R1
Schiavi, P1
Guez, D1
Jean, T1
Del Rio, M1
Chulia, T1
Merchan-Perez, A1
Remezal, M1
Valor, S1
Gonzalez, J1
Gutierrez, JA1
Contreras, JA1
Lasuncion, MA1
Tejerina, T1
Matheson, AJ1
Cheer, SM1
Goa, KL1
Boucher, FR1
Schatz, CJ1
Guez, DM1
de Leiris, JG1
Delbarre, B1
Delbarre, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open-label, Single-center, Single-arm Futility Trial Evaluating Oral Hydroxychloroquine 200mg BID for Reducing Progression of Disability in Patients With Primary Progressive Multiple Sclerosis (PPMS)[NCT02913157]Phase 235 participants (Actual)Interventional2016-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for indapamide and Disease Models, Animal

ArticleYear
Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension.
    Drugs, 2001, Volume: 61, Issue:8

    Topics: Adult; Age Factors; Aged; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal;

2001

Trials

1 trial available for indapamide and Disease Models, Animal

ArticleYear
Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arterioles; Blood

2011

Other Studies

8 other studies available for indapamide and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Combination of Hydroxychloroquine and Indapamide Attenuates Neurodegeneration in Models Relevant to Multiple Sclerosis.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:1

    Topics: Animals; Brain; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; Female; Humans;

2021
Recent trends in hypertension treatment: perspectives from animal studies.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2009, Volume: 27, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Female; Hu

2009
Chronic and acute effects of different antihypertensive drugs on femoral artery relaxation of L-NAME hypertensive rats.
    Physiological research, 2007, Volume: 56 Suppl 2

    Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pre

2007
Study of antiatherogenic properties of indapamide in a pharmacologic model.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 6

    Topics: Animals; Arteriosclerosis; Basement Membrane; Body Weight; Carotid Arteries; Cell Division; Choleste

1993
Effects of indapamide on atherosclerosis development in cholesterol-fed rabbits.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Aorta; Arteriosclerosis; Blood Pressure; Bod

1995
Beneficial effect of indapamide in experimental myocardial ischemia.
    American journal of hypertension, 1992, Volume: 5, Issue:1

    Topics: Animals; Coronary Disease; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Glutathione

1992
Effect of indapamide on an experimental model of cerebral ischemia in hypertensive rats.
    The American journal of medicine, 1988, Jan-29, Volume: 84, Issue:1B

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug E

1988