indapamide has been researched along with Diabetic Glomerulosclerosis in 16 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test whether microalbuminuria in patients with type 2 diabetes and hypertension is primarily dependent on the severity of hypertension, and to compare the effectiveness of two antihypertensive drugs with opposite effects on the renin-angiotensin system [the diuretic, indapamide sustained release (SR), and an angiotensin-converting enzyme inhibitor, enalapril] in reducing microalbuminuria." | 9.11 | Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study. ( Amouyel, P; Asmar, R; Fernandez, M; Finizola, B; Gallois, Y; Halabe, A; Hermansen, K; Ionescu-Tirgoviste, C; Jermendy, G; Kokot, F; Marre, M; Mion Júnior, D; Moyseev, V; Ollivier, JP; Opie, L; Puig, JG; Ruiz, M; Saldanha, MH; Scheen, A; Tuomilehto, J; Williams, B, 2004) |
| " In this study, 21 patients with noninsulin-dependent diabetes and hypertension (11 with normoalbuminuria and 10 with microalbuminuria), who were comparable for age, duration of diabetes and hypertension, were treated with indapamide, 2." | 7.68 | Efficacy of antihypertensive treatment with indapamide in patients with noninsulin-dependent diabetes and persistent microalbuminuria. ( Frontoni, S; Gambardella, S; Gargiulo, P; Grazia Felici, M; Menzinger, G; Morano, S; Spallone, V, 1990) |
| "To test whether microalbuminuria in patients with type 2 diabetes and hypertension is primarily dependent on the severity of hypertension, and to compare the effectiveness of two antihypertensive drugs with opposite effects on the renin-angiotensin system [the diuretic, indapamide sustained release (SR), and an angiotensin-converting enzyme inhibitor, enalapril] in reducing microalbuminuria." | 5.11 | Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study. ( Amouyel, P; Asmar, R; Fernandez, M; Finizola, B; Gallois, Y; Halabe, A; Hermansen, K; Ionescu-Tirgoviste, C; Jermendy, G; Kokot, F; Marre, M; Mion Júnior, D; Moyseev, V; Ollivier, JP; Opie, L; Puig, JG; Ruiz, M; Saldanha, MH; Scheen, A; Tuomilehto, J; Williams, B, 2004) |
| " In this study, 21 patients with noninsulin-dependent diabetes and hypertension (11 with normoalbuminuria and 10 with microalbuminuria), who were comparable for age, duration of diabetes and hypertension, were treated with indapamide, 2." | 3.68 | Efficacy of antihypertensive treatment with indapamide in patients with noninsulin-dependent diabetes and persistent microalbuminuria. ( Frontoni, S; Gambardella, S; Gargiulo, P; Grazia Felici, M; Menzinger, G; Morano, S; Spallone, V, 1990) |
| "Patients with type 2 diabetes were randomized to perindopril-indapamide (4 mg/1." | 2.75 | Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease. ( Cass, A; Chalmers, J; Cooper, M; Grobbee, DE; Heerspink, HJ; Mancia, G; Mogensen, CE; Neal, B; Ninomiya, T; Perkovic, V; Woodward, M; Zoungas, S, 2010) |
| "A total of 11140 individuals with type 2 diabetes were randomly assigned to fixed combination perindopril-indapamide or matching placebo, after a 6-week run-in period." | 2.73 | Blood pressure lowering with fixed combination perindopril-indapamide: key findings from ADVANCE. ( Chalmers, J; Joshi, R; Kengne, AP; MacMahon, S, 2008) |
| "Patients with type 2 diabetes mellitus exhibit a marked increase in cardiovascular and renal risk." | 2.45 | The ADVANCE trial: clarifying the role of perindopril/indapamide fixed-dose combination in the reduction of cardiovascular and renal events in patients with diabetes mellitus. ( de la Sierra, A; Ruilope, LM; Waeber, B, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohkuma, T | 1 |
| Jun, M | 1 |
| Rodgers, A | 1 |
| Cooper, ME | 1 |
| Glasziou, P | 2 |
| Hamet, P | 3 |
| Harrap, S | 2 |
| Mancia, G | 3 |
| Marre, M | 4 |
| Neal, B | 3 |
| Perkovic, V | 3 |
| Poulter, N | 2 |
| Williams, B | 4 |
| Zoungas, S | 2 |
| Chalmers, J | 4 |
| Woodward, M | 3 |
| Joshi, R | 1 |
| Kengne, AP | 1 |
| MacMahon, S | 2 |
| de Galan, BE | 1 |
| Ninomiya, T | 2 |
| Pillai, A | 1 |
| Patel, A | 1 |
| Cass, A | 2 |
| Mogensen, CE | 2 |
| Cooper, M | 2 |
| Grobbee, DE | 2 |
| Waeber, B | 1 |
| de la Sierra, A | 1 |
| Ruilope, LM | 2 |
| Heerspink, HJ | 1 |
| Koya, D | 1 |
| Nedogoda, SV | 1 |
| Garcia Puig, J | 1 |
| Kokot, F | 2 |
| Fernandez, M | 2 |
| Jermendy, G | 2 |
| Opie, L | 2 |
| Moyseev, V | 2 |
| Scheen, A | 2 |
| Ionescu-Tirgoviste, C | 2 |
| Saldanha, MH | 2 |
| Halabe, A | 2 |
| Mion, D | 1 |
| Ruiz, M | 2 |
| Hermansen, K | 2 |
| Tuomilehto, J | 2 |
| Finizola, B | 2 |
| Pozza, G | 1 |
| Chastang, C | 1 |
| Ollivier, JP | 2 |
| Amouyel, P | 2 |
| Asmar, R | 2 |
| Puig, JG | 1 |
| Mion Júnior, D | 1 |
| Gallois, Y | 1 |
| Basturk, T | 1 |
| Altuntaş, Y | 1 |
| Kurklu, A | 1 |
| Aydin, L | 1 |
| Eren, N | 1 |
| Unsal, A | 1 |
| Segura, J | 1 |
| Scheen, AJ | 1 |
| Krzesinski, JM | 1 |
| Donnelly, R | 1 |
| Molyneaux, LM | 2 |
| Willey, KA | 2 |
| Yue, DK | 2 |
| Gambardella, S | 1 |
| Frontoni, S | 1 |
| Grazia Felici, M | 1 |
| Spallone, V | 1 |
| Gargiulo, P | 1 |
| Morano, S | 1 |
| Menzinger, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925] | Phase 3 | 11,140 participants (Actual) | Interventional | 2001-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for indapamide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
The ADVANCE trial: clarifying the role of perindopril/indapamide fixed-dose combination in the reduction of cardiovascular and renal events in patients with diabetes mellitus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus | 2009 |
What matters in ADVANCE and ADVANCE-ON.
Topics: Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diabete | 2012 |
Renal protection in diabetic patients: benefits of a first-line combination of perindopril-indapamide (Preterax).
Topics: Albuminuria; Antihypertensive Agents; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic | 2006 |
Comparative effects of indapamide and captopril on blood pressure and albumin excretion rate in diabetic microalbuminuria.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calc | 1996 |
10 trials available for indapamide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Acute Increases in Serum Creatinine After Starting Angiotensin-Converting Enzyme Inhibitor-Based Therapy and Effects of its Continuation on Major Clinical Outcomes in Type 2 Diabetes Mellitus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabe | 2019 |
Blood pressure lowering with fixed combination perindopril-indapamide: key findings from ADVANCE.
Topics: Aged; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Female; | 2008 |
Lowering blood pressure reduces renal events in type 2 diabetes.
Topics: Age of Onset; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2009 |
Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combinatio | 2010 |
[Lowering blood pressure and glucose reduces renal events in type 2 diabetes; ADVANCE study].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diabetic Nephropathies; D | 2010 |
Effect of indapamide SR on microalbuminuria--the NESTOR study (Natrilix SR versus Enalapril Study in Type 2 diabetic hypertensives with micrOalbuminuRia)--rationale and protocol for the main trial.
Topics: Adult; Aged; Albuminuria; Clinical Protocols; Creatine; Delayed-Action Preparations; Diabetes Mellit | 2003 |
Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study.
Topics: Aged; Albuminuria; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Doubl | 2004 |
[Clinical trial of the month. ADVANCE: improved survival and better vascular and renal outcomes with a fixed combination of perindopril and indapamide in patients with type 2 diabetes].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Di | 2007 |
Comparative effects of indapamide and captopril on blood pressure and albumin excretion rate in diabetic microalbuminuria.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calc | 1996 |
Indapamide is as effective as captopril in the control of microalbuminuria in diabetes.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cross-Ove | 1996 |
3 other studies available for indapamide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
[Nephroprotection diabetes mellitus type 2: lessons from the ADVANCE trial].
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combinatio | 2011 |
Urinary N-acetyl B glucosaminidase as an earlier marker of diabetic nephropathy and influence of low-dose perindopril/indapamide combination.
Topics: Acetylglucosaminidase; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers | 2006 |
Efficacy of antihypertensive treatment with indapamide in patients with noninsulin-dependent diabetes and persistent microalbuminuria.
Topics: Adult; Albuminuria; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies | 1990 |