Page last updated: 2024-10-29

indapamide and Dementia

indapamide has been researched along with Dementia in 7 studies

Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"Incident dementia was a secondary endpoint and was not significantly different between the two treatment groups."2.78Increased pulse pressure linked to dementia: further results from the Hypertension in the Very Elderly Trial - HYVET. ( Beckett, N; Bulpitt, C; Fagard, R; Fletcher, A; Forette, F; Pereira, L; Peters, R; Thijs, L; Wang, JG, 2013)
"depression is common in elderly people and may be associated with increased cardiovascular risk and incident dementia."2.75Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Fletcher, A; Grimley-Evans, J; McCormack, T; Nunes, M; Peters, R; Pinto, E; Potter, J; Swift, C, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ostroumova, OD1
Starodubova, AV1
Ostroumova, TM1
Cherniaeva, MS1
Peters, R3
Beckett, N3
Fagard, R1
Thijs, L1
Wang, JG1
Forette, F2
Pereira, L1
Fletcher, A3
Bulpitt, C3
Tuomilehto, J1
Clarke, R1
Ritchie, C1
Waldman, A1
Walton, I1
Poulter, R1
Ma, S1
Comsa, M1
Burch, L1
Pinto, E1
Swift, C1
Potter, J1
McCormack, T1
Nunes, M1
Grimley-Evans, J1
Mukhtar, O1
Jackson, SH1
Tzourio, C1
Anderson, C1
Chapman, N1
Woodward, M1
Neal, B1
MacMahon, S1
Chalmers, J1
Widimský, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Hypertension in the Very Elderly Trial (HYVET)[NCT00122811]Phase 44,000 participants (Anticipated)Interventional2000-11-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for indapamide and Dementia

ArticleYear
The Hypertension in the Very Elderly Trial - latest data.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:4

    Topics: Aged, 80 and over; Antihypertensive Agents; Cognition Disorders; Delayed-Action Preparations; Dement

2013

Trials

4 trials available for indapamide and Dementia

ArticleYear
Increased pulse pressure linked to dementia: further results from the Hypertension in the Very Elderly Trial - HYVET.
    Journal of hypertension, 2013, Volume: 31, Issue:9

    Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cognition; Dementia; Double-Blind Method

2013
Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial.
    The Lancet. Neurology, 2008, Volume: 7, Issue:8

    Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cognition; Dementia; Double-Blind Method

2008
Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET).
    Age and ageing, 2010, Volume: 39, Issue:4

    Topics: Aged, 80 and over; Antihypertensive Agents; Cardiovascular Diseases; Dementia; Depression; Female; G

2010
Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.
    Archives of internal medicine, 2003, May-12, Volume: 163, Issue:9

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cerebrovasc

2003

Other Studies

2 other studies available for indapamide and Dementia

ArticleYear
[Cognitive Disorders and Dementia in Old Patients With Arterial Hypertension].
    Kardiologiia, 2018, Issue:10

    Topics: Antihypertensive Agents; Blood Pressure; Cognition; Dementia; Humans; Hypertension; Indapamide

2018
[Management of dementia and cognitive functions in patients after cerebrovascular stroke: new results from the PROGRESS study].
    Vnitrni lekarstvi, 2003, Volume: 49, Issue:4

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cognition Disorders; Dementia; Humans; Hypertensio

2003