Page last updated: 2024-10-29

indapamide and Cardiovascular Diseases

indapamide has been researched along with Cardiovascular Diseases in 44 studies

Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"This study was a subsidiary analysis of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS)--a randomized, placebo-controlled trial that established the beneficial effects of blood pressure--lowering in a heterogeneous group of patients with cerebrovascular disease."9.11Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack. ( Anderson, C; Arima, H; Chalmers, J; Colman, S; Hart, RG; MacMahon, S; Neal, B; Rodgers, A; Woodward, M, 2005)
"To study effects of perindopril, indapamid and their combination on stratification of essential hypertension (EH) risk factors."9.09[Effects of perindopril and its combination with indapamide on risk stratification in patients with hypertension]. ( Ol'binskaia, LI; Zheleznykh, EA, 2001)
"A systematic literature search is undertaken for supporting the pharmacological proprieties and clinical efficacy of perindopril in the treatment of hypertension."8.87Perindopril for the treatment of hypertension. ( Ghiadoni, L, 2011)
"Hypertension is an important risk factor for cardiovascular complications and the need to treat this condition has been well established."6.47Combination perindopril/indapamide for the treatment of hypertension: a review. ( de Leeuw, PW, 2011)
" The fixed dosage of a once-daily tablet, ensures optimal ease of use and enhances patient compliance."6.43Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection. ( Gosse, P, 2006)
"The Hypertension in the Very Elderly Trial (HYVET) was a double blind placebo-controlled trial of antihypertensive treatment (indapamide SR 1."5.14Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis. ( Beckett, N; Bulpitt, C; Clarke, R; Fletcher, A; Forette, F; Peters, R; Poulter, R; Ritchie, C; Tuomilehto, J; Waldman, A; Walton, I, 2009)
"This study was a subsidiary analysis of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS)--a randomized, placebo-controlled trial that established the beneficial effects of blood pressure--lowering in a heterogeneous group of patients with cerebrovascular disease."5.11Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack. ( Anderson, C; Arima, H; Chalmers, J; Colman, S; Hart, RG; MacMahon, S; Neal, B; Rodgers, A; Woodward, M, 2005)
"To study effects of perindopril, indapamid and their combination on stratification of essential hypertension (EH) risk factors."5.09[Effects of perindopril and its combination with indapamide on risk stratification in patients with hypertension]. ( Ol'binskaia, LI; Zheleznykh, EA, 2001)
"A systematic literature search is undertaken for supporting the pharmacological proprieties and clinical efficacy of perindopril in the treatment of hypertension."4.87Perindopril for the treatment of hypertension. ( Ghiadoni, L, 2011)
" Results from HYVET (Hypertension in the Very Elderly Trial) showed that, at 2-year follow-up, antihypertensive drug therapy with indapamide, plus perindopril if needed, reduced fatal or nonfatal stroke by 30%, fatal stroke by 39%, all-cause mortality by 21%, cardiovascular death by 23%, and heart failure by 64%."3.74Older age should not be a barrier to the treatment of hypertension. ( Aronow, WS, 2008)
"5 mg of indapamide retard with or without addition of 2-4 mg of perindopril, 30% lowering of risk of development of fatal and nonfatal stroke (95% confidence interval [CI] -1 to 51, p=0."3.74[Arterial hypertension in persons older than 80 years: the problem can be successfully solved]. ( Batyraliev, TA; Fettser, DV; Ishlek, M; Preobrazhenskiĭ, DV; Sidorenko, BA, 2008)
" While randomized trials have demonstrated that blood pressure lowering reduces vascular complications in subjects with type 2 diabetes and hypertension, ADVANCE was designed to determine whether the addition of a fixed combination of perindopril and indapamide, on top of comprehensive and effective cardiovascular treatments and glucose control therapy, would produce further benefits, irrespective of the initial blood pressure."3.74Advances in reducing the burden of vascular disease in type 2 diabetes. ( Chalmers, J; Joshi, R; Patel, A, 2008)
"Weight loss is strongly recommended for overweight and obese adults with type 2 diabetes."2.94The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE. ( Chalmers, J; Hamet, P; Harrap, S; Lee, AK; Marre, M; Mcevoy, JW; Ohkuma, T; Selvin, E; Sharrett, AR; Wang, D; Warren, B; Williams, B; Woodward, M, 2020)
"11,140 participants with type 2 diabetes, from the ADVANCE trial, were randomized to perindopril-indapamide or matching placebo."2.77Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes. ( Beulens, JW; Chalmers, J; Cooper, ME; Grobbee, DE; Harrap, S; Kengne, AP; Mancia, G; Neal, B; Patel, A; Poulter, N; van der Schouw, YT; van Dieren, S; Woodward, M; Zoungas, S, 2012)
"depression is common in elderly people and may be associated with increased cardiovascular risk and incident dementia."2.75Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Fletcher, A; Grimley-Evans, J; McCormack, T; Nunes, M; Peters, R; Pinto, E; Potter, J; Swift, C, 2010)
"In this cohort of men with type 2 diabetes, ED was associated with a range of CVD events."2.75Erectile dysfunction and later cardiovascular disease in men with type 2 diabetes: prospective cohort study based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) trial. ( Batty, GD; Chalmers, J; Czernichow, S; de Galan, BE; Hamet, P; Harrap, SB; Huxley, R; Li, Q; Neal, B; Patel, A; Poulter, N; Woodward, M; Zoungas, S, 2010)
"Hypertension is an important risk factor for cardiovascular complications and the need to treat this condition has been well established."2.47Combination perindopril/indapamide for the treatment of hypertension: a review. ( de Leeuw, PW, 2011)
" The fixed dosage of a once-daily tablet, ensures optimal ease of use and enhances patient compliance."2.43Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection. ( Gosse, P, 2006)
" We sought to estimate individual beneficial and adverse effects of intensive glucose control in patients with type 2 diabetes."1.43Estimation of individual beneficial and adverse effects of intensive glucose control for patients with type 2 diabetes. ( Chalmers, J; Grobbee, DE; Harrap, S; Heller, S; Mancia, G; Marre, M; Poulter, N; van der Graaf, Y; van der Leeuw, J; Visseren, FL; Woodward, M; Zoungas, S, 2016)
"Perindopril/indapamide was well tolerated with no significant changes in laboratory parameters being observed."1.37Efficacy and safety of treatment of hypertensive patients with fixed combination perindopril/indapamide up to 10/2.5 mg: results of the FALCO FORTE programme. ( Pella, D, 2011)
"Factors that must be considered for the treatment of hypertension in patients, particularly with type 2 diabetes."1.31[Reflexion of French experts on the key points of the symposium]. ( Dubourg, O; Forette, F; Hanon, O; Mallion, JM; Marre, M, 2002)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's22 (50.00)29.6817
2010's19 (43.18)24.3611
2020's3 (6.82)2.80

Authors

AuthorsStudies
Podzolkov, VI1
Bragina, AЕ1
Rodionova, YN1
Bragina, GI1
Bykova, EE1
Lee, AK1
Woodward, M12
Wang, D1
Ohkuma, T4
Warren, B1
Sharrett, AR1
Williams, B3
Marre, M7
Hamet, P8
Harrap, S6
Mcevoy, JW2
Chalmers, J13
Selvin, E2
Tian, J1
Cooper, M2
Mancia, G5
Poulter, N7
Wang, JG1
Zoungas, S9
Jun, M1
Rodgers, A3
Cooper, ME2
Glasziou, P2
Neal, B6
Perkovic, V1
Pereira, BC1
Isreb, A1
Forbes, RT1
Dores, F1
Habashy, R1
Petit, JB1
Alhnan, MA1
Oga, EF1
Rahman, F1
Muntner, P1
Konig, M1
Lamos, EM1
Stein, SA1
Davis, SN1
Beckett, N3
Peters, R4
Leonetti, G1
Duggan, J1
Fagard, R1
Thijs, L2
Narkiewicz, K1
McCormack, T2
Banya, W2
Fletcher, A3
Bulpitt, C3
van der Leeuw, J2
Visseren, FL2
Kengne, AP5
van der Graaf, Y2
MacMahon, S2
Grobbee, DE5
Thomopoulos, C1
Parati, G1
Zanchetti, A1
Hirakawa, Y1
Matthews, DR1
Patel, A6
Grobbee, R1
Jardine, M1
Heller, S3
Agnew, T1
Tropeano, AI2
Katsahian, S1
Molle, D1
Grimaldi, A1
Laurent, S2
Waeber, B1
Burnier, M1
Lüscher, T1
Hess, O1
Aronow, WS1
Lundberg, GD1
Hedner, T1
Kjeldsen, S1
Oparil, S1
Narkiewics, K1
Preobrazhenskiĭ, DV1
Sidorenko, BA1
Batyraliev, TA1
Fettser, DV1
Ishlek, M1
Forette, F3
Tuomilehto, J1
Ritchie, C1
Walton, I1
Waldman, A1
Clarke, R1
Poulter, R1
Mourad, JJ1
Le Jeune, S1
Rump, LC1
Nitschmann, S1
Colagiuri, S2
Pan, CY1
Pinto, E1
Swift, C1
Potter, J1
Nunes, M1
Grimley-Evans, J1
Batty, GD1
Li, Q1
Czernichow, S1
Huxley, R1
de Galan, BE1
Harrap, SB1
Angeli, F1
Reboldi, G1
Verdecchia, P1
Travert, F1
Lievre, M1
Ghiadoni, L1
de Leeuw, PW1
Pella, D1
van Dieren, S1
Beulens, JW1
van der Schouw, YT1
Kaplan, NM1
Mallion, JM1
Hanon, O1
Dubourg, O1
Toblli, JE1
DeRosa, G1
Rivas, C1
Cao, G1
Piorno, P1
Pagano, P1
Forcada, P1
Arima, H1
Hart, RG1
Colman, S1
Anderson, C2
Gosse, P1
Boutouyrie, P1
Scheen, AJ1
Krzesinski, JM1
Joshi, R1
Beckett, NS1
Fletcher, AE1
Staessen, JA1
Liu, L1
Dumitrascu, D1
Stoyanovsky, V1
Antikainen, RL1
Nikitin, Y1
Belhani, A1
Rajkumar, C1
Bulpitt, CJ1
Ol'binskaia, LI1
Zheleznykh, EA1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925]Phase 311,140 participants (Actual)Interventional2001-06-30Completed
Evaluation of the HeartWare Left Ventricular Assist Device for the Treatment of Advanced Heart Failure[NCT00751972]140 participants (Actual)Interventional2008-08-31Completed
The Hypertension in the Very Elderly Trial (HYVET)[NCT00122811]Phase 44,000 participants (Anticipated)Interventional2000-11-30Active, not recruiting
Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761]Phase 4471 participants (Actual)Interventional2018-02-13Completed
Essential Arterial Hypotension and Allostasis Registry[NCT02018497]5,000 participants (Anticipated)Observational [Patient Registry]1995-01-31Recruiting
Estudio RioplateNsE Sobre Telemonitoreo en hIpertensos No-controlAdos[NCT02730052]0 participants (Actual)Interventional2016-12-31Withdrawn (stopped due to Centers recruited poorly)
Morbidity and Mortality Based on Blood Pressure and Arterial Stiffness in Institutionalized Persons Aged 80 and Over: Study PARTAGE (Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population).[NCT00901355]1,130 participants (Actual)Observational2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Distance Walked in the 6-minute Walk Test Between Baseline and 180 Days

"The 6MWT is a simple test which does not require expensive equipment or advanced training for technicians. The test involves asking the patient to walk the longest distance possible in a set interval of 6 min, through a walking course (corridor) preferably 30-m long. The patient can stop or slow down at any time and then resume walking, depending on his/her degree of fatigue.~A longer distance walked is indicative of a better outcome." (NCT00751972)
Timeframe: Baseline and 180 Days

Interventionmeters (Mean)
HeartWare® VAS150.14

Quality of Life Change From Baseline to 180 Days, as Measured by EuroQoL EQ-5D

"The EQ-5D is a standardized instrument for use as a generic measure of the quality of health-related life and of health outcome.~The EuroQoL EQ-5D is a descriptive system of health-related quality of life states consisting of five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) each of which can take one of five responses. The responses record five levels of severity (no problems/slight problems/moderate problems/severe problems/extreme problems) within a particular EQ-5D dimension.~Scores are transformed to a range of 0-100, in which higher scores reflect better health status." (NCT00751972)
Timeframe: Baseline and 180 Days

Interventionunits on a EuroQol EQ-5D scale (Mean)
HeartWare® VAS29.53

Quality of Life Change From Baseline to 180 Days, as Measured by Kansas City Cardiomyopathy Questionnaire (KCCQ)

"KCCQ is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life for patients with congestive heart failure. It is a predictive tool that tracks how patients are doing if they have weakened heart muscle due to prior heart attacks, heart valve problems, viral infections, or other causes.~The KCCQ's questions are used to calculate scores in ten domains:~Physical Limitation, Symptom Stability, Frequency, Burden and Total Symptom. Social Limitation, Self-Efficacy, Quality of Life, and Clinical Summary. Overall Summary: a combined measure of all the above~For each domain, the validity, reproducibility, responsiveness and interpretability have been independently established. Scores are transformed to a range of 0-100, in which higher scores reflect better health status." (NCT00751972)
Timeframe: Baseline and 180 Days

Interventionunits on a KCCQ scale (Mean)
HeartWare® VAS30.94

Survival to 180 Days

All subjects will be followed for date of death until 180 days. (NCT00751972)
Timeframe: 180 Days

InterventionPercentage of participants with survival (Number)
HeartWare® VAS94.3
Contemporaneous Control91.2

The Primary Endpoint is Success at 180 Days Which is Defined as Alive on the Originally Implanted HeartWare® LVAD or Transplanted or Explanted for Recovery. Patient Must Survive 60 Days Post-explant for Recovery to be Considered Successful.

The primary endpoint is success at 180 days which is defined as alive on the originally implanted HeartWare® LVAD or transplanted or explanted for recovery. A patient must survive 60 days post-explant for recovery to be considered successful. (NCT00751972)
Timeframe: 180 days

InterventionPercentage of participants with success (Number)
HeartWare® VAS90.7
Contemporaneous Control90.1

Incidence of Adverse Events, Neurocognitive Status and Unanticipated Adverse Device Effects

Adverse events are only provided for patients who received a HeartWare Ventricular Assist Device (HeartWare® VAS). Adverse events as described by INTERMACS for the contemporaneous control population were not a part of the agreement for analysis and thus not provided by INTERMACS, and so not included in the Adverse Event Module and relevant Outcome Measures for comparison. (NCT00751972)
Timeframe: 180 Days

Interventionpercentage of patients (Number)
Bleeding requiring reoperationInfections - LocalInfections - DrivelineInfections - SepsisNeurologic Event-Ischemic Cerebrovascular accidentNeurologic Event-Hemorrhagic CVANeurologic Event - Transient Ischemic Attack(TIA)ARight Heart Failure - requiring InotropesRight Heart Failure - requiring RVADRespiratory DysfunctionArterial ThromboembolismVenous ThromboembolismRenal DysfunctionHepatic DysfunctionHemolysis
HeartWare® VAS17.125.012.111.47.14.34.316.02.919.32.96.45.72.93.6

Incidence of All Device Failures and Device Malfunctions

The INTERMACS event device malfunction defined a failure of the HeartWare VAS as either pump failure or non-pump failure. (NCT00751972)
Timeframe: 180 Days

InterventionNumber of events (Number)
Pump Failure (exchange)Non pump failure
HeartWare® VAS719

Reviews

7 reviews available for indapamide and Cardiovascular Diseases

ArticleYear
An insight into the recent diabetes trials: what is the best approach to prevent macrovascular and microvascular complications?
    Current diabetes reviews, 2013, Volume: 9, Issue:5

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Typ

2013
Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses.
    Journal of hypertension, 2015, Volume: 33, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2015
Perindopril for the treatment of hypertension.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:10

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardi

2011
Combination perindopril/indapamide for the treatment of hypertension: a review.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:11

    Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Humans; Hyperte

2011
What matters in ADVANCE and ADVANCE-ON.
    Diabetes, obesity & metabolism, 2012, Volume: 14 Suppl 1

    Topics: Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diabete

2012
Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection.
    Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2006
Pulse pressure reduction and cardiovascular protection.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2006, Volume: 24, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Di

2006

Trials

17 trials available for indapamide and Cardiovascular Diseases

ArticleYear
The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE.
    The Journal of clinical endocrinology and metabolism, 2020, 01-01, Volume: 105, Issue:1

    Topics: Adult; Aged; Body-Weight Trajectory; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Combin

2020
Effects of Intensive Glycemic Control on Clinical Outcomes Among Patients With Type 2 Diabetes With Different Levels of Cardiovascular Risk and Hemoglobin A
    Diabetes care, 2020, Volume: 43, Issue:6

    Topics: Aged; Blood Glucose; Cardiovascular Diseases; Delayed-Action Preparations; Diabetes Mellitus, Type 2

2020
Acute Increases in Serum Creatinine After Starting Angiotensin-Converting Enzyme Inhibitor-Based Therapy and Effects of its Continuation on Major Clinical Outcomes in Type 2 Diabetes Mellitus.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabe

2019
Effects of Blood Pressure Lowering on Clinical Outcomes According to Baseline Blood Pressure and Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:6

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes

2019
Subgroup and per-protocol analyses from the Hypertension in the Very Elderly Trial.
    Journal of hypertension, 2014, Volume: 32, Issue:7

    Topics: Age Factors; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; De

2014
Predicting the effects of blood pressure-lowering treatment on major cardiovascular events for individual patients with type 2 diabetes mellitus: results from Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:1

    Topics: Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diabetes Mell

2015
Lowering of brachial pulse pressure in 9379 hypertensives with type 2 diabetes and reduction of cardiovascular events.
    Blood pressure, 2008, Volume: 17, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cohort Studies; D

2008
Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis.
    International psychogeriatrics, 2009, Volume: 21, Issue:2

    Topics: Aged, 80 and over; Antihypertensive Agents; Cardiovascular Diseases; Cognition Disorders; Comorbidit

2009
The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax
    Diabetologia, 2010, Volume: 53, Issue:5

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; D

2010
Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET).
    Age and ageing, 2010, Volume: 39, Issue:4

    Topics: Aged, 80 and over; Antihypertensive Agents; Cardiovascular Diseases; Dementia; Depression; Female; G

2010
Erectile dysfunction and later cardiovascular disease in men with type 2 diabetes: prospective cohort study based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) trial.
    Journal of the American College of Cardiology, 2010, Nov-30, Volume: 56, Issue:23

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Delayed-A

2010
Contemporary model for cardiovascular risk prediction in people with type 2 diabetes.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2011, Volume: 18, Issue:3

    Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Asia; Australasia; Blood Glucose; Canad

2011
Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes.
    Diabetes research and clinical practice, 2012, Volume: 98, Issue:1

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; D

2012
Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Atrial Fibr

2005
[Clinical trial of the month. ADVANCE: improved survival and better vascular and renal outcomes with a fixed combination of perindopril and indapamide in patients with type 2 diabetes].
    Revue medicale de Liege, 2007, Volume: 62, Issue:10

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Di

2007
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Treatment of hypertension in patients 80 years of age or older.
    The New England journal of medicine, 2008, May-01, Volume: 358, Issue:18

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
[Effects of perindopril and its combination with indapamide on risk stratification in patients with hypertension].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:9

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Diuretics; Drug Therapy, Combination; Female; Huma

2001

Other Studies

20 other studies available for indapamide and Cardiovascular Diseases

ArticleYear
[Tactics of antihypertensive therapy during COVID-19 pandemic].
    Terapevticheskii arkhiv, 2021, Sep-15, Volume: 93, Issue:9

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; COVID-19

2021
'Temporary Plasticiser': A novel solution to fabricate 3D printed patient-centred cardiovascular 'Polypill' architectures.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 135

    Topics: Amlodipine; Cardiovascular Agents; Cardiovascular Diseases; Chemistry, Pharmaceutical; Crystallizati

2019
Prediction of 10-year vascular risk in patients with diabetes: the AD-ON risk score.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:3

    Topics: Aged; Antihypertensive Agents; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopat

2016
Estimation of individual beneficial and adverse effects of intensive glucose control for patients with type 2 diabetes.
    Diabetologia, 2016, Volume: 59, Issue:12

    Topics: Aged; Antihypertensive Agents; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Combinations

2016
Slow release diuretics save lives.
    Nursing older people, 2008, Volume: 20, Issue:4

    Topics: Aged, 80 and over; Cardiovascular Diseases; Delayed-Action Preparations; Diuretics; Humans; Hyperten

2008
[Need of antihypertensive therapy in patients aged 80 years or more].
    Praxis, 2008, May-14, Volume: 97, Issue:10

    Topics: Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, C

2008
Older age should not be a barrier to the treatment of hypertension.
    Nature clinical practice. Cardiovascular medicine, 2008, Volume: 5, Issue:9

    Topics: Age Factors; Aged, 80 and over; Aging; Antihypertensive Agents; Cardiovascular Diseases; Drug Therap

2008
Study shows benefit of hypertension help after 80.
    The Johns Hopkins medical letter health after 50, 2008, Volume: 20, Issue:7

    Topics: Aged, 80 and over; Aging; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; In

2008
You should treat patients over the age of 80 who have hypertension.
    Medscape journal of medicine, 2008, Volume: 10, Issue:8

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2008
Management of older hypertensive patients.
    Blood pressure, 2008, Volume: 17, Issue:4

    Topics: Age Factors; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Ch

2008
[Arterial hypertension in persons older than 80 years: the problem can be successfully solved].
    Kardiologiia, 2008, Volume: 48, Issue:11

    Topics: Age Factors; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; C

2008
Heart protection: a key target in the management of patients with diabetes.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2009, Volume: 27, Issue:1

    Topics: Blood Pressure; Cardiovascular Diseases; Diabetes Complications; Humans; Hypertension; Indapamide; P

2009
[Treatment of hypertension in patients older than 80 years].
    Der Internist, 2009, Volume: 50, Issue:9

    Topics: Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure

2009
More than a REASON to use arterial stiffness as risk marker and therapeutic target in hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:4

    Topics: Antihypertensive Agents; Aorta; Atenolol; Blood Flow Velocity; Blood Pressure; Brachial Artery; Card

2011
Efficacy and safety of treatment of hypertensive patients with fixed combination perindopril/indapamide up to 10/2.5 mg: results of the FALCO FORTE programme.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2011, Sep-01, Volume: 18, Issue:3

    Topics: Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood

2011
[The challenge to treat hypertensive patients with type 2 diabetes].
    Presse medicale (Paris, France : 1983), 2002, Volume: 31 Spec No 2

    Topics: Adult; Albuminuria; Antihypertensive Agents; Body Mass Index; Cardiovascular Diseases; Diabetes Mell

2002
[Reflexion of French experts on the key points of the symposium].
    Presse medicale (Paris, France : 1983), 2002, Volume: 31 Spec No 2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Albuminuria; Angiotensin-Converting Enzyme Inhibitors;

2002
Cardiovascular protective role of a low-dose antihypertensive combination in obese Zucker rats.
    Journal of hypertension, 2003, Volume: 21, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiova

2003
Advances in reducing the burden of vascular disease in type 2 diabetes.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:4

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type

2008
[Results of ADVANCE trial conducted in type 2 diabetic patients].
    Terapevticheskii arkhiv, 2008, Volume: 80, Issue:1

    Topics: Cardiovascular Diseases; Congresses as Topic; Diabetes Mellitus, Type 2; Drug Combinations; Europe;

2008