indapamide has been researched along with Cardiomegaly in 12 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indapamide is a new, nonthiazide diuretic and vasodilator." | 6.67 | Regression of left ventricular hypertrophy in hypertension with indapamide. ( Haichin, R; Sami, M, 1991) |
| "Indapamide-treated animals had significantly greater myocardial cAMP concentrations than control animals." | 5.29 | Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy. ( Rabkin, SW, 1993) |
| "To compare clinical efficacy and tolerance of fixed combinations of perindopril and indapamide (noliprel), capoten+hydrochlorotiaside (caposide) in arterial hypertension stage I-II of high and very high risk which failed prior monotherapy." | 5.11 | [Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk]. ( Brel', UA; Chaliabi, TA; Kapustin, IO; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VA, 2005) |
| "The aim was to compare the effects of two diuretics, indapamide and hydrochlorothiazide, on cardiac hypertrophy in stroke prone spontaneously hypertensive rats (SHR-SP)." | 3.68 | Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat. ( Contard, F; Glukhova, M; Guez, D; Marotte, F; Narcisse, G; Rappaport, L; Samuel, JL; Schatz, C; Swynghedauw, B, 1993) |
| "Indapamide is a new, nonthiazide diuretic and vasodilator." | 2.67 | Regression of left ventricular hypertrophy in hypertension with indapamide. ( Haichin, R; Sami, M, 1991) |
| "Indapamide-treated animals had significantly greater myocardial cAMP concentrations than control animals." | 1.29 | Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy. ( Rabkin, SW, 1993) |
| "Renal hypertrophy was also decreased significantly by cicletanine at a dose of 100 mg/kg." | 1.27 | Comparison of cicletanine with other antihypertensive drugs in SHR-SP models. ( Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nedogoda, SV | 1 |
| Marchenko, IV | 1 |
| Chaliabi, TA | 1 |
| Tsoma, VA | 1 |
| Brel', UA | 1 |
| Prokhorova, EA | 1 |
| Kapustin, IO | 1 |
| Opie, LH | 1 |
| Contard, F | 2 |
| Glukhova, M | 2 |
| Sabri, A | 1 |
| Marotte, F | 2 |
| Sartore, S | 1 |
| Narcisse, G | 2 |
| Schatz, C | 2 |
| Guez, D | 4 |
| Rappaport, L | 2 |
| Samuel, JL | 3 |
| Rabkin, SW | 1 |
| Swynghedauw, B | 1 |
| Levy, BI | 1 |
| Duriez, M | 1 |
| Sami, M | 1 |
| Haichin, R | 1 |
| Komajda, M | 2 |
| Klimczak, K | 2 |
| Boutin, B | 2 |
| Brackman, F | 2 |
| Grosgogeat, Y | 2 |
| Evans, J | 1 |
| Mace, PJ | 1 |
| Littler, WA | 1 |
| Glover, DR | 1 |
| Rowlands, DB | 1 |
| Stallard, TJ | 1 |
| Malherbe, E | 2 |
| Le Hegarat, M | 2 |
| Clostre, F | 2 |
| Braquet, P | 2 |
| Auguet, M | 1 |
| Delaflotte, S | 1 |
| Baranes, J | 1 |
1 review available for indapamide and Cardiomegaly
| Article | Year |
|---|---|
[Long-term effects of indapamide in left ventricular hypertrophy in patients with hypertension].
Topics: Adult; Aged; Cardiomegaly; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Middle A | 1990 |
3 trials available for indapamide and Cardiomegaly
| Article | Year |
|---|---|
[Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk].
Topics: Antihypertensive Agents; Captopril; Cardiomegaly; Female; Heart Ventricles; Humans; Hydrochlorothiaz | 2005 |
Regression of left ventricular hypertrophy in hypertension with indapamide.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Humans; Hypertension; Indapamide; Middl | 1991 |
Regression of left ventricular hypertrophy in hypertension: comparative effects of three different drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Female; Humans; Hypert | 1985 |
8 other studies available for indapamide and Cardiomegaly
| Article | Year |
|---|---|
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
Comparative effects of indapamide and hydrochlorothiazide on cardiac hypertrophy and vascular smooth-muscle phenotype in the stroke-prone, spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Hydrochlorothiazide; Hypertension; Indapami | 1993 |
Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Binding, Competitive; Carbachol; Cardiomegaly; | 1993 |
Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Evaluation, Preclinical; Fibrosis; Hyd | 1993 |
Coronary microvasculature alteration in hypertensive rats. Effect of treatment with a diuretic and an ACE inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Coronary Circulatio | 2001 |
Effects of indapamide on left ventricular mass and function in systemic hypertension with left ventricular hypertrophy.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Diuretics; Echocardiography; Female; Follow-Up Studies; H | 1990 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Di | 1988 |
Antihypertensive profile of cicletanine, a furopyridine derivative: comparison with captopril, indapamide and prazosin.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Cardiomegaly; Diuresis; Diuretic | 1988 |