indapamide has been researched along with Cardiac Hypertrophy in 12 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indapamide is a new, nonthiazide diuretic and vasodilator." | 6.67 | Regression of left ventricular hypertrophy in hypertension with indapamide. ( Haichin, R; Sami, M, 1991) |
| "Indapamide-treated animals had significantly greater myocardial cAMP concentrations than control animals." | 5.29 | Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy. ( Rabkin, SW, 1993) |
| "To compare clinical efficacy and tolerance of fixed combinations of perindopril and indapamide (noliprel), capoten+hydrochlorotiaside (caposide) in arterial hypertension stage I-II of high and very high risk which failed prior monotherapy." | 5.11 | [Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk]. ( Brel', UA; Chaliabi, TA; Kapustin, IO; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VA, 2005) |
| "The aim was to compare the effects of two diuretics, indapamide and hydrochlorothiazide, on cardiac hypertrophy in stroke prone spontaneously hypertensive rats (SHR-SP)." | 3.68 | Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat. ( Contard, F; Glukhova, M; Guez, D; Marotte, F; Narcisse, G; Rappaport, L; Samuel, JL; Schatz, C; Swynghedauw, B, 1993) |
| "Indapamide is a new, nonthiazide diuretic and vasodilator." | 2.67 | Regression of left ventricular hypertrophy in hypertension with indapamide. ( Haichin, R; Sami, M, 1991) |
| "Indapamide-treated animals had significantly greater myocardial cAMP concentrations than control animals." | 1.29 | Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy. ( Rabkin, SW, 1993) |
| "Renal hypertrophy was also decreased significantly by cicletanine at a dose of 100 mg/kg." | 1.27 | Comparison of cicletanine with other antihypertensive drugs in SHR-SP models. ( Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nedogoda, SV | 1 |
| Marchenko, IV | 1 |
| Chaliabi, TA | 1 |
| Tsoma, VA | 1 |
| Brel', UA | 1 |
| Prokhorova, EA | 1 |
| Kapustin, IO | 1 |
| Opie, LH | 1 |
| Contard, F | 2 |
| Glukhova, M | 2 |
| Sabri, A | 1 |
| Marotte, F | 2 |
| Sartore, S | 1 |
| Narcisse, G | 2 |
| Schatz, C | 2 |
| Guez, D | 4 |
| Rappaport, L | 2 |
| Samuel, JL | 3 |
| Rabkin, SW | 1 |
| Swynghedauw, B | 1 |
| Levy, BI | 1 |
| Duriez, M | 1 |
| Sami, M | 1 |
| Haichin, R | 1 |
| Komajda, M | 2 |
| Klimczak, K | 2 |
| Boutin, B | 2 |
| Brackman, F | 2 |
| Grosgogeat, Y | 2 |
| Evans, J | 1 |
| Mace, PJ | 1 |
| Littler, WA | 1 |
| Glover, DR | 1 |
| Rowlands, DB | 1 |
| Stallard, TJ | 1 |
| Malherbe, E | 2 |
| Le Hegarat, M | 2 |
| Clostre, F | 2 |
| Braquet, P | 2 |
| Auguet, M | 1 |
| Delaflotte, S | 1 |
| Baranes, J | 1 |
1 review available for indapamide and Cardiac Hypertrophy
| Article | Year |
|---|---|
[Long-term effects of indapamide in left ventricular hypertrophy in patients with hypertension].
Topics: Adult; Aged; Cardiomegaly; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Middle A | 1990 |
3 trials available for indapamide and Cardiac Hypertrophy
| Article | Year |
|---|---|
[Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk].
Topics: Antihypertensive Agents; Captopril; Cardiomegaly; Female; Heart Ventricles; Humans; Hydrochlorothiaz | 2005 |
Regression of left ventricular hypertrophy in hypertension with indapamide.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Humans; Hypertension; Indapamide; Middl | 1991 |
Regression of left ventricular hypertrophy in hypertension: comparative effects of three different drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Female; Humans; Hypert | 1985 |
8 other studies available for indapamide and Cardiac Hypertrophy
| Article | Year |
|---|---|
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
Comparative effects of indapamide and hydrochlorothiazide on cardiac hypertrophy and vascular smooth-muscle phenotype in the stroke-prone, spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Hydrochlorothiazide; Hypertension; Indapami | 1993 |
Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Binding, Competitive; Carbachol; Cardiomegaly; | 1993 |
Diuretic effects on cardiac hypertrophy in the stroke prone spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Evaluation, Preclinical; Fibrosis; Hyd | 1993 |
Coronary microvasculature alteration in hypertensive rats. Effect of treatment with a diuretic and an ACE inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Coronary Circulatio | 2001 |
Effects of indapamide on left ventricular mass and function in systemic hypertension with left ventricular hypertrophy.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Diuretics; Echocardiography; Female; Follow-Up Studies; H | 1990 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Di | 1988 |
Antihypertensive profile of cicletanine, a furopyridine derivative: comparison with captopril, indapamide and prazosin.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Cardiomegaly; Diuresis; Diuretic | 1988 |