indapamide has been researched along with Aging in 8 studies
Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "the Hypertension in the Very Elderly Trial (HYVET) was a double-blind placebo-controlled trial of a thiazide-like diuretic (indapamide 1." | 9.14 | The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Burch, L; de Vernejoul, MC; Duggan, J; Fletcher, A; Gil-Extremera, B; Liu, L; Peters, R; Swift, C, 2010) |
| "the Hypertension in the Very Elderly Trial (HYVET) was a randomised placebo-controlled trial of indapamide slow release 1." | 5.17 | Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial. ( Beckett, N; Bulpitt, C; Burch, L; Fagard, R; Fletcher, A; Li, M; Narkiewicz, K; Nitsch, D; Peters, R; Poulter, R; Wang, N, 2013) |
| "the Hypertension in the Very Elderly Trial (HYVET) was a double-blind placebo-controlled trial of a thiazide-like diuretic (indapamide 1." | 5.14 | The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET). ( Beckett, N; Bulpitt, C; Burch, L; de Vernejoul, MC; Duggan, J; Fletcher, A; Gil-Extremera, B; Liu, L; Peters, R; Swift, C, 2010) |
| " Results from HYVET (Hypertension in the Very Elderly Trial) showed that, at 2-year follow-up, antihypertensive drug therapy with indapamide, plus perindopril if needed, reduced fatal or nonfatal stroke by 30%, fatal stroke by 39%, all-cause mortality by 21%, cardiovascular death by 23%, and heart failure by 64%." | 3.74 | Older age should not be a barrier to the treatment of hypertension. ( Aronow, WS, 2008) |
| "Indapamide serum binding was increased in patients with inflammatory syndrome (82." | 1.27 | Serum binding of indapamide in health and disease: primary role of alpha 1-acid glycoprotein. ( Coulomb, B; d'Athis, P; Morin, D; Tillement, JP; Urien, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Michaels, NJ | 1 |
| Lemmon, K | 1 |
| Plemel, JR | 1 |
| Jensen, SK | 1 |
| Mishra, MK | 1 |
| Brown, D | 1 |
| Rawji, KS | 1 |
| Koch, M | 1 |
| Yong, VW | 1 |
| Aronow, WS | 1 |
| Peters, R | 2 |
| Beckett, N | 2 |
| Burch, L | 2 |
| de Vernejoul, MC | 1 |
| Liu, L | 1 |
| Duggan, J | 1 |
| Swift, C | 1 |
| Gil-Extremera, B | 1 |
| Fletcher, A | 2 |
| Bulpitt, C | 2 |
| Poulter, R | 1 |
| Narkiewicz, K | 1 |
| Fagard, R | 1 |
| Nitsch, D | 1 |
| Wang, N | 1 |
| Li, M | 1 |
| Wheeley, MS | 1 |
| Bolton, JC | 1 |
| Campbell, DB | 1 |
| Safar, M | 1 |
| Laurent, S | 1 |
| Safavian, A | 1 |
| Pannier, B | 1 |
| Asmar, R | 1 |
| Urien, S | 1 |
| Morin, D | 1 |
| d'Athis, P | 1 |
| Coulomb, B | 1 |
| Tillement, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Hypertension in the Very Elderly Trial (HYVET)[NCT00122811] | Phase 4 | 4,000 participants (Anticipated) | Interventional | 2000-11-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for indapamide and Aging
| Article | Year |
|---|---|
Sodium and large arteries in hypertension. Effects of indapamide.
Topics: Aging; Arteries; Blood Pressure; Diuretics; Humans; Hypertension; Indapamide; Pulse; Sodium; Vascula | 1988 |
2 trials available for indapamide and Aging
| Article | Year |
|---|---|
The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged, 80 and over; Aging; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Fractu | 2010 |
Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.
Topics: Age Factors; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Ag | 2013 |
5 other studies available for indapamide and Aging
| Article | Year |
|---|---|
Aging-Exacerbated Acute Axon and Myelin Injury Is Associated with Microglia-Derived Reactive Oxygen Species and Is Alleviated by the Generic Medication Indapamide.
Topics: Aging; Animals; Antihypertensive Agents; Axons; Demyelinating Diseases; Drugs, Generic; Female; Inda | 2020 |
Older age should not be a barrier to the treatment of hypertension.
Topics: Age Factors; Aged, 80 and over; Aging; Antihypertensive Agents; Cardiovascular Diseases; Drug Therap | 2008 |
Study shows benefit of hypertension help after 80.
Topics: Aged, 80 and over; Aging; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; In | 2008 |
Indapamide in hypertension: a study in general practice of new or previously poorly controlled patients.
Topics: Aged; Aging; Blood Pressure; Diuretics; Humans; Hypertension; Indapamide; Time Factors | 1982 |
Serum binding of indapamide in health and disease: primary role of alpha 1-acid glycoprotein.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Diuretics; Fatty Acids, Nonesterified; Female; Hu | 1988 |