incednine and Heart-Failure

Atrial fibrillation (AF) and heart failure (HF) often accompany one another, and each is independently associated with poor outcomes. However, the association between AF burden and outcomes is poorly understood.. The purpose of this study was to describe the association between device-based AF burden and HF clinical outcomes.. We used a nationwide, remote monitoring database of cardiac implantable electronic devices (CIEDs) linked to Medicare claims. We included patients with nonpermanent AF, undergoing new CIED implant, stratified by baseline HF. The outcomes were new-onset HF, HF hospitalization, and all-cause mortality at 1 and 3 years.. We identified 39,710 patients who met inclusion criteria (25,054 with HF; 14,656 without HF). Patients with HF were younger (mean age 76.3 vs 78.5 years; P <.001), more often male (65% vs 54%; P <.001), and had higher mean CHA. Among older patients with AF receiving a CIED, increasing AF burden is significantly associated with increasing risk of adverse HF outcomes and all-cause mortality.

Topics: Aged; Atrial Fibrillation; Cardiac Resynchronization Therapy Devices; Disaccharides; Female; Follow-Up Studies; Heart Failure; Humans; Lactams; Male; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; United States