imirestat has been researched along with Alloxan Diabetes in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (29.41) | 18.7374 |
| 1990's | 9 (52.94) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blessing, K; Hamada, T; Kador, PF; Reinhardt, RA | 1 |
| Blessing, K; Kador, PF; Marx, DB; O'Meara, JD; Reinhardt, RA | 1 |
| Caspers-Velu, LE; Kador, PF; Rapoport, SI; Wadhwani, KC | 2 |
| Dunlop, ME; Keogh, RJ; Larkins, RG | 1 |
| Glover, JP; Hosotani, H; Jacot, JL; Lois, N; Robison, WG | 1 |
| Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF | 1 |
| Fan, W; Hu, Y; Li, G; Yan, M | 1 |
| Blessing, K; Fujisawa, S; Kador, PF; Lee, JW; Lou, MF | 1 |
| Diemel, LT; Stevens, EJ; Tomlinson, DR; Willars, GB | 1 |
| Barker, R; Barratt, D; Brazzell, K; DuPriest, M; Griffin, B; Mayer, P; Park, YH; York, B | 1 |
| Calcutt, NA; Carrington, AL; Ettlinger, CB; Tomlinson, DR | 1 |
| Chang, K; Eades, DM; Kilo, C; Province, MA; Pugliese, G; Sherman, WR; Tilton, RG; Williamson, JR | 1 |
| Chandler, ML; Griffin, BW; McNatt, LG; York, BM | 1 |
| Dickerson, JE; Garadi, R; Lou, MF; York, BM | 1 |
| Broderick, CL; Fuller, RW; Hemrick-Luecke, SK; Perry, KW; Yen, TT | 1 |
| Blouin, RA; Brazzell, RK; McNamara, PJ | 1 |
17 other study(ies) available for imirestat and Alloxan Diabetes
| Article | Year |
|---|---|
Effect of an aldose reductase inhibitor on alveolar bone loss associated with periodontitis in diabetic rats.
Topics: Aldehyde Reductase; Alveolar Bone Loss; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Fluorenes; Hydantoins; Lipopolysaccharides; Male; Maxillary Diseases; Periodontitis; Rats; Rats, Sprague-Dawley; Streptozocin | 2010 |
Efficacy of structurally diverse aldose reductase inhibitors on experimental periodontitis in rats.
Topics: Aldehyde Reductase; Alveolar Bone Loss; Animals; Antioxidants; Citric Acid Cycle; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Glycolysis; Hydantoins; Lipopolysaccharides; Male; Naphthalenes; Periodontitis; Quercetin; Rats; Rats, Sprague-Dawley; Sorbitol | 2011 |
Permeability of the blood-retinal and blood-aqueous barriers in galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Autoradiography; Blood-Aqueous Barrier; Blood-Retinal Barrier; Capillary Permeability; Ciliary Body; Coloring Agents; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme Inhibitors; Female; Fluorenes; Galactose; Hydantoins; Iris; Microscopy, Fluorescence; Peroxidases; Rats; Rats, Sprague-Dawley; Retinal Vessels; Sucrose | 1995 |
Effect of inhibition of aldose reductase on glucose flux, diacylglycerol formation, protein kinase C, and phospholipase A2 activation.
Topics: Aldehyde Reductase; Animals; Arachidonic Acids; Cell Membrane; Diabetes Mellitus, Experimental; Diglycerides; Enzyme Activation; Fluorenes; Glucose; Hydantoins; Hyperglycemia; In Vitro Techniques; Kidney Glomerulus; Male; Phospholipases A; Phospholipases A2; Prostaglandins E; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sorbitol; Streptozocin; Time Factors | 1997 |
Diabetic-like corneal sensitivity loss in galactose-fed rats ameliorated with aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Blinking; Cataract; Cornea; Diabetes Mellitus, Experimental; Diet; Enzyme Inhibitors; Fluorenes; Galactose; Galactosemias; Hydantoins; Male; Physical Stimulation; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones | 1998 |
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; L-Iditol 2-Dehydrogenase; Phthalazines; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley | 1998 |
Iris vasculopathy in galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Blood Vessels; Blood-Aqueous Barrier; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme Inhibitors; Evans Blue; Female; Fluorenes; Galactose; Horseradish Peroxidase; Hydantoins; Iris; Microscopy, Electron; Permeability; Rats; Rats, Sprague-Dawley | 1999 |
[The role of lens epithelium in cataract formation in diabetic rats].
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Epithelium; Female; Fluorenes; Hydantoins; Lens, Crystalline; Male; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 1998 |
Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fluorenes; Glutathione; Glycation End Products, Advanced; Glycosylation; Hydantoins; Lens, Crystalline; Naphthalenes; Phthalazines; Rats; Rats, Sprague-Dawley; Sorbitol; Spectrometry, Fluorescence | 2000 |
Depletion of substance P and calcitonin gene-related peptide in sciatic nerve of rats with experimental diabetes; effects of insulin and aldose reductase inhibition.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Calcitonin Gene-Related Peptide; Diabetes Mellitus, Experimental; Fluorenes; Fructose; Glucose; Hydantoins; Inositol; Insulin; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Sorbitol; Substance P | 1992 |
Pharmacokinetics and efficacy of structurally related spirohydantoin and spirosuccinimide aldose reductase inhibitors.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Crystallins; Diabetes Mellitus, Experimental; Female; Fluorenes; Hydantoins; Injections, Intravenous; Ketamine; Macaca fascicularis; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Spiro Compounds; Structure-Activity Relationship; Succinimides | 1992 |
Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats.
Topics: Action Potentials; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Electric Conductivity; Electrophysiology; Fluorenes; Fructose; Glucose; Hydantoins; Hypoxia; Insulin; Male; Neural Conduction; Ouabain; Rats; Rats, Inbred Strains; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Sorbitol; Streptozocin | 1991 |
Prevention of hemodynamic and vascular albumin filtration changes in diabetic rats by aldose reductase inhibitors.
Topics: Albuminuria; Aldehyde Reductase; Animals; Cardiac Output; Diabetes Mellitus, Experimental; Fluorenes; Glomerular Filtration Rate; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Iodine Radioisotopes; Male; Naphthalenes; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Serum Albumin, Bovine; Sorbitol; Strontium; Sugar Alcohol Dehydrogenases; Vascular Resistance | 1989 |
Effects of two new aldose reductase inhibitors, AL-1567 and AL-1576, in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Female; Fluorenes; Humans; Hydantoins; In Vitro Techniques; Kinetics; Lens, Crystalline; Male; Placenta; Rats; Rats, Inbred Strains; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases | 1987 |
Glutathione depletion in the lens of galactosemic and diabetic rats.
Topics: Aldehyde Reductase; Aminoisobutyric Acids; Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Fluorenes; Galactitol; Galactosemias; Glutathione; Glutathione Reductase; Hydantoins; Lens, Crystalline; Male; NAD; NADP; Rats; Rats, Inbred Strains; Sorbitol | 1988 |
AL-1576, an aldose reductase inhibitor (ARI), did not prevent the decrease of norepinephrine turnover in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Female; Fluorenes; Hydantoins; Lens, Crystalline; Norepinephrine; Rats; Rats, Inbred Strains; Sorbitol; Sugar Alcohol Dehydrogenases | 1988 |
The protein binding of phenytoin, propranolol, diazepam, and AL01576 (an aldose reductase inhibitor) in human and rat diabetic serum.
Topics: Adult; Aldehyde Reductase; Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diazepam; Fluorenes; Humans; Hydantoins; Male; Phenytoin; Propranolol; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Sugar Alcohol Dehydrogenases | 1988 |