imiquimod has been researched along with Inflammation in 269 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.37) | 18.2507 |
| 2000's | 13 (4.83) | 29.6817 |
| 2010's | 106 (39.41) | 24.3611 |
| 2020's | 149 (55.39) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Chen, C; Dai, L; Liu, J; Liu, L; Pan, Y; Sui, Q; Sun, H; Sun, L; Wen, X; You, Y; Yuan, H | 1 |
| Aagaard, A; Bäck, E; Chen, R; Collins, M; Grindebacke, H; Hansson, EL; Hansson, TG; Hossain, N; Hughes, G; Jirholt, J; Krutrök, N; Leffler, A; Lepistö, M; Lever, S; Llinas, A; Malmberg, A; Malmberg, J; McPheat, J; Narjes, F; Olsson, RI; Pehrson, R; Ramnegård, M; Svanberg, P; Thunberg, L; von Berg, S; Xiong, Y; Xue, Y | 1 |
| Kong, L; Li, M; Lv, W; Meng, S; Qiao, H; Song, C; Sun, Y; Wang, X; Yang, C; Zhu, Y | 1 |
| Gao, J; Li, X; Ma, X; Miao, Y; Wei, W; Xi, B; Yang, C; Zhang, J; Zhou, H | 1 |
| Chen, C; Duan, Q; Liu, M; Shao, Y; Sun, Q; Wang, M; Wang, Y; Zhang, M; Zheng, Y | 1 |
| Hu, Z; Huang, N; Li, J; Liu, X; Ma, T; Wang, Z; Wei, X; Wu, W; Zhang, J; Zhen, H; Zhou, H | 1 |
| Alalaiwe, A; Chang, ZY; Chen, CY; Chuang, SY; Fang, JY; Sung, JT | 1 |
| Kang, J; Khang, D; Kim, N; Kim, SH; Kwon, TK; Lee, S | 1 |
| Chen, C; Chen, X; Chen, Z; Dou, X; Huang, C; Huang, H; Huang, X; Jian, X; Jiang, B; Li, Z; Liu, X; Ren, X; Shen, C; Yang, L; Yu, B; Zhong, W | 1 |
| Albanesi, C; Madonna, S; Mercurio, L; Morelli, M; Pallotta, S; Scaglione, GL; Scarponi, C | 1 |
| Agócs, R; Dobosy, P; Kemény, L; Németh, I; Pajtók, C; Pap, D; Szabó, AJ; Szebeni, B; Tulassay, T; Vannay, Á; Veréb, Z; Veres-Székely, A | 1 |
| Al-Awqati, M; Palasiewicz, K; Shahrara, S; Sweiss, N; Umar, S; Volin, MV; Zanotti, B | 1 |
| Iida, K; Ishikawa, J; Iwamoto, T; Iwata, A; Kageyama, T; Makita, S; Nakajima, H; Suto, A; Suzuki, K; Tanaka, S; Yabe, Y; Yokota, M | 1 |
| Blauvelt, A; Boki, H; Kimura, T; Miyagaki, T; Okochi, H; Sato, S; Suga, H; Sugaya, M | 1 |
| Bocheńska, K; Gabig-Cimińska, M; Moskot, M | 1 |
| Cheng, G; Kuang, H; Su, Y; Wang, Q; Wu, L; Zhang, F | 1 |
| Chen, Y; He, Y; Li, W; Ma, Y; Shangguan, Y; Zhao, Y | 1 |
| Alalaiwe, A; Chuang, SY; Fang, JY; Huang, TH; Lin, CF; Nguyen, TMH; Wang, PW | 1 |
| Assani, I; Chen, L; Huang, RZ; Jin, Q; Kang, YY; Li, Y; Liao, ZX; Lv, SM; Su, M; Sun, B; Wang, CG; Wang, DZ; Wang, JW; Wang, MX; Wu, XZ; Zhao, SF | 1 |
| Cao, G; Cao, Z; Liu, Z; Shi, Y; Sun, R; Xu, Q; Yang, N; Zhang, C | 1 |
| Han, D; Li, F; Lu, S; Meng, L; Mou, K; Wang, B; Xu, J; Zhang, W; Zhao, Y; Zhou, Y; Zhu, W | 1 |
| Bayik, D; Braley, C; Chandrasekharan, UM; de Windt, N; DiCorleto, PE; Fernandez, AP; Harvey, JE; Hsieh, J; Husni, ME; Jaini, R; Kaur, R; Lee, M; Rai, V; Scheraga, RG | 1 |
| Chen, J; Dang, E; Fang, H; Li, Q; Ma, J; Pang, B; Qiao, H; Qiao, P; Shao, S; Sun, Z; Wang, G; Wang, L; Xue, K; Yu, C | 1 |
| Cui, J; Li, W; Sun, H; Zhai, S; Zhang, P; Zhao, Y | 1 |
| Lin, X; Liu, Q; Qian, J; Tang, J; Xie, Q; Xiong, S; Zhou, Z | 1 |
| Guo, H; Li, M; Liu, H | 1 |
| Cheng, H; Du, X; Li, M; Mei, X; Pan, Y; Tian, D; Yang, L; Zhang, D | 1 |
| Chung, JH; Jo, SJ; Kim, EJ; Kim, SJ; Kim, TG; Lee, Y; Ohn, J; Suh, JH | 1 |
| Chen, Y; Chen, Z; Guo, C; Hu, Y; Shi, Y; Wang, Y; Xu, P; Yu, Q; Yu, Z; Zhang, X; Zhao, Z; Zhou, X | 1 |
| Alarcón, B; Borroto, A; Navarro, MN | 1 |
| Cheng, LY; Deng, Y; Feng, XY; Guo, DJ; Guo, WJ; Hua, L; Li, FL; Liu, X; Wang, Y; Xi, RF; Ze, K; Zhu, JY; Zhu, SJ | 1 |
| Dang, N; Fan, H; Huang, S; Li, X; Liu, N; Ma, G; Qin, L; Wang, J; Yang, T; Zhang, P | 1 |
| Fang, X; Li, W; Ling, S; Liu, X; Luo, Y; Wang, A; Xu, B; Yao, X; Zhang, S; Zhou, Y; Zong, W | 1 |
| Bonifaz, LC; Cancino-Diaz, JC; Cancino-Diaz, ME; Castro-Escamilla, O; Martínez-Torres, I; Perez-Tapia, SM; Rodríguez-Martínez, S; Tepale-Segura, A | 1 |
| Ahmad, SF; Al-Harbi, NO; Alanazi, AZ; Alasmari, F; Alharbi, M; Alhazzani, K; Almutairi, M; Alqahtani, F; Alqarni, SA; Ibrahim, KE; Nadeem, A | 1 |
| Bieler, T; Daiber, A; Karbach, S; Keller, K; Knopp, T; Kropp, A; Lagrange, J; Molitor, M; Münzel, T; Rauh, M; Ringen, J; Sies, K; Titze, J; Waisman, A; Wenzel, P; Wild, J | 1 |
| Fu, FH; Li, XX; Lin, YW; Liu, B; Ma, L; Qi, R; Xing, X | 1 |
| Correa Atella, G; Donato-Trancoso, A; Romana-Souza, B | 1 |
| Adachi, A; Egawa, G; Gunzer, M; Honda, T; Hossain, MR; Ikuta, K; Kabashima, K; Kanameishi, S; Komine, M; Miyake, T; Ohtsuki, M; Takimoto, R | 1 |
| Cho, H; Hwang, ES; Je, JH; Jeon, Y; Jeong, MG; Kang, J; Lee, K; Song, J | 1 |
| Chen, XY; Landeck, L; Man, XY; Wang, P; Wang, ZY; Xu, F; Yan, BX; Zheng, M; Zhou, Y | 1 |
| Chen, X; Kuang, Y; Li, J; Liu, N; Liu, P; Peng, C; Yan, B; Yi, X; Zhu, W | 1 |
| Cai, Y; Chen, L; Ding, C; Hu, X; Li, X; Liu, N; Qin, H; Rouchka, EC; Tieri, D; Wang, L; Xu, Q; Xue, F; Yan, J; Zheng, J | 1 |
| Abe, T; Hida, T; Ichimiya, S; Ikegami, I; Inoue, KI; Kamada, Y; Kamekura, R; Kamiya, S; Kamiya, T; Kobayashi, K; Sato, T; Takaki, H; Uhara, H; Yanagi, M | 1 |
| Chen, X; Chen, Y; Hu, W; Hua, L; Liang, S; Ou, Y; Sun, P; Wu, X; Yang, X; Yang, Z; Yue, H; Zhou, Y | 1 |
| Bai, Y; Cao, L; Chen, S; Chen, W; Fan, W; Ge, H; Li, B; Li, Z; Liu, M; Luo, S; Mao, Y; Shen, J; Sun, L; Wang, D; Wang, Y; Yong, L; Yu, Y; Zhang, C; Zhang, R; Zhen, Q | 1 |
| Chen, Z; Gao, WQ; Hao, W; Lin, J; Tang, J; Wang, L; Xu, H; Yang, M; You, Q; Zhao, X | 1 |
| Dai, C; Guo, X; Jiang, F; Wang, J; Wu, X; Yin, Q | 1 |
| Chen, Y; Chikazawa, S; Ichimasu, N; Katagiri, K; Kobayashi, K; Suzuki, S | 1 |
| Hou, JJ; Jia, HY; Qiu, HY; Wu, Y; Zhang, MD; Zhou, ML | 1 |
| Huang, J; Jin, H; Wang, Y | 1 |
| Chen, D; Chen, G; Lin, J; Lin, Y; Liu, A; Luo, T; Ouyang, D; Pan, H; Qin, M; Zhou, X | 1 |
| Duan, J; Duan, R; Gao, S; Li, J; Li, X; Ma, X; Qin, Y; Shi, R; Zhang, L; Zhao, R | 1 |
| Li, H; Wang, J; Wang, S; Xiong, Y; Zhou, X | 1 |
| Chen, H; Ge, W; Huang, Y; Jiang, J; Jin, Z; Kong, Y; Li, F; Li, L; Li, M; Liu, X; Zeng, X; Zhanmu, O | 1 |
| Chen, C; Chen, M; Chen, X; Hou, G; Kuang, Y; Li, J; Li, L; Lin, L; Liu, P; Peng, C; Su, J; Yan, B; Zhu, W | 1 |
| Chenyang, W; Fushida, N; Hamaguchi, Y; Horii, M; Ikawa, Y; Kitano, T; Komuro, A; Matsushita, T; Nakabori, I; Sawada, K; Xibei, J | 1 |
| Bhavana, V; Chary, PS; Mehra, NK; Pardhi, E; Singh, SB; Sulthana, S | 1 |
| Li, K; Nandakumar, KS; Ou, J; Wang, T; Wu, H | 1 |
| Kim, J; Kim, KI; Lee, A; Lim, JS; Park, KC | 1 |
| Banfi, G; Casciano, F; Gornati, L; Granucci, F; Guerrini, R; Marzola, E; Mingozzi, F; Montico, G; Protti, G; Reali, E; Secchiero, P; Volinia, S | 1 |
| Lian, LH; Nan, JX; Wu, YL; Yang, HX; Zhan, ZY; Zhang, ZH | 1 |
| Christensen, PKF; Hansen, AK; Høyer-Hansen, MH; Koch, J; Larsen, J; Martel, BC; Skov, S | 1 |
| Clausen, BE; Hsiao, YP; Kelel, M; Lee, CH; Lee, YL; Liang, PH; Liu, FT; Lu, CH; Su, SH; Tan, YF; Tsai, CH; Tsai, TF; Weng, HJ; Yeh, CY | 1 |
| Hartmann, JN; Häsler, R; Philippsen, R; Piticchio, SG; Rose-John, S; Schwarz, A; Schwarz, T | 1 |
| Chen, X; Lei, Y; Liu, Y; Lyu, C; Yang, Y; Ye, Y; Zhang, T; Zhou, X | 1 |
| Burnet, M; Cloos, N; Cruces, S; Fischer, T; Geiger, J; Geiger, S; Guezguez, J; Guse, JH; Keppler, M; Laufer, S; Martorelli, M; Riexinger, L; Sandri, TL; Schwamborn, A; Späth, N; Straß, S | 1 |
| Chodaczek, G; Kupczyk, P; Makarec, A; Makuch, S; Woźniak, M; Ziółkowski, P | 1 |
| Chang, YC; Chen, CH; Chen, PJ; Chen, SH; Fang, SY; Hwang, TL; Tsai, SC; Tsai, YF; Tseng, HH; Wang, YH | 1 |
| Benoist, C; Hanna, BS; Hsu, YC; Mathis, D; Ortiz-Lopez, A; Sassone-Corsi, M; Shwartz, Y; Zarin, P | 1 |
| Hillman, PF; Jung, YR; Kang, JH; Kang, TB; Kim, JH; Lee, SB; Nam, SJ; Sim, EJ | 1 |
| Chen, X; He, Y; Huang, X; Jia, H; Liu, T; Shan, W; Sun, R; Yang, Q | 1 |
| Chen, X; Chu, C; Han, J; Huang, X; Li, X; Lin, Z; Wang, F; Xiong, Y; Xu, R | 1 |
| Bang, J; Bareja, R; Desman, G; Ding, W; Elemento, O; Eljalby, M; Granstein, RD; Miller, LS; Reilly, MD; Vyas, NS; You, J; Yusupova, M; Zippin, JH | 1 |
| Li, G; Li, L; Li, S; Li, X; Wu, F | 1 |
| Cai, X; Du, J; Gao, W; Gong, H; Lu, H; Xiao, H; Xu, J; Yang, Y | 1 |
| Liu, Q; Ren, C; Wang, D; Wang, Q; Zhang, H | 1 |
| Dai, SM; Deng, H; Guo, M; Liu, N; Liu, W; Meng, Q; Su, Y; Wei, M; Zhuang, H | 1 |
| Endo, K; Makabe, H; Nakashima, A; Sawa, T; Tanaka, S; Tanaka, Y | 1 |
| Lin, J; Lin, P; Lu, YY; Shi, HY | 1 |
| Luo, F; Luo, M; Pan, Y; Peng, Y; Ran, C; Wang, B; Wang, H; Wang, L; Yan, YN; Yi, T; Zhang, Y; Zhou, R | 1 |
| Antal, D; Bai, P; Demény, MÁ; Dull, K; Kiss, B; Kovács, I; Póliska, S; Pór, Á; Szántó, M; Szegedi, A; Szöllősi, AG; Ujlaki, G | 1 |
| An, B; Hong, N; Kong, Q; Liu, F; Sang, H; Shan, Y; Wu, Y; Yu, P; Zhang, X | 1 |
| Bai, Y; Chen, W; Ge, H; Li, B; Li, Z; Liu, H; Mao, Y; Sun, L; Wang, D; Wang, Y; Yu, Y; Zhen, Q | 1 |
| Pu, S; Sun, L; Zhao, K; Zhou, D | 1 |
| Li, Y; Liu, Q; Ma, X; Wang, A; Wei, F; Zhang, H | 1 |
| Bhattacharyya, S; Gorai, P; Modak, BK; Mondal, A; Mondal, NK; Pramanik, A; Sarkar, D | 1 |
| Becker, M; Bezdek, S; Bieber, K; Gross, N; Gullberg, D; Gupta, Y; Hdnah, A; Ibrahim, SM; Künzel, S; Ludwig, RJ; Mousavi, S; Prüssmann, J; Sadik, CD; Sayegh, JP; Sezin, T; Vorobyev, A | 1 |
| Chan, CI; Chen, SJ; Hseu, JH; Hseu, YC; Vadivalagan, C; Wu, PY; Yang, HL; Yen, HR | 1 |
| Cai, Z; Wang, W; Zeng, Y; Zhang, Y | 1 |
| Chen, H; Chen, Q; Chen, S; Chen, X; Chen, Y; Gu, H; Li, M; Lian, N; Yang, Y; Zhang, Y | 1 |
| Chen, J; Ding, B; Huang, Z; Liang, L; Qian, Y; Zhou, Y; Zhu, L | 1 |
| Ansari, B; Dashti, M; Haghnavaz, N; Moghadam, M; Pordel, S; Rezaee, M; Sankian, M; Shobeiri, SS | 1 |
| Jing, X; Liu, Z; Meng, L; Su, H; Zhang, Z | 1 |
| Askari, VR; Baradaran Rahimi, V; Golmohammadzadeh, S; Jaafari, MR; Kamali, H; Rahmanian-Devin, P; Sanei-Far, Z | 1 |
| Collado-Diaz, V; Friess, MC; Hagedorn, O; Haghayegh Jahromi, N; Halin, C; Jadhav, M; Leroux, JC; Polomska, A; Proulx, ST; Vallone, A; Vranova, M; Willrodt, AH | 1 |
| Chen, H; Dai, Z; Deng, J; Han, L; Liang, CL; Liu, C; Liu, H; Lu, C; Wang, Y; Wei, J; Yan, Y | 1 |
| Azam, T; Beckman, K; de Graaf, DM; Dinarello, CA; Fischer, S; Fujita, M; Højen, JF; Kristensen, MLV; Lunding, LP; McKee, AS; Swartzwelter, BJ; Tolstrup, M; Wade, MT; Wegmann, M | 1 |
| Cheng, WJ; Chiang, CC; Hwang, TL; Ju, SC; Lai, KH; Lee, C; Lin, CY; Yang, SH | 1 |
| Carmichael, DJ; Han, G; Havnaer, A; Lee, HH; Martinez, LR | 1 |
| Ai, D; Feng, S; Liu, Y; Ma, J; Yang, X | 1 |
| Antal, D; Bai, P; Hegedűs, C; Kiss, B; Márton, J; Méhes, G; Szántó, M; Szegedi, A; Szödényi, A; Virág, L | 1 |
| Du, Z; Li, N; Lu, C; Wu, D; Yuan, X; Zhang, M; Zhu, W | 1 |
| Godugu, C; Pooladanda, V; Sigalapalli, DK; Thatikonda, S | 1 |
| Fujimoto, M; Fujisawa, Y; Furuta, J; Inoue, S; Ishitsuka, Y; Nakamura, Y; Ogawa, T; Okiyama, N; Saito, A; Watanabe, R | 1 |
| Croft, M; Han, KH; Kang, YJ; Miki, H; Scott, D | 1 |
| Chang, DC; Hsiao, CY; Hung, CF; Li, HJ; Pu, CM; Wu, NL | 1 |
| Fallon, PG; Hernández-Santana, YE; Leon, G; St Leger, D; Walsh, PT | 1 |
| Blanco, LP; Carmona-Rivera, C; Goel, RR; Gupta, S; Hasneen, K; Kaplan, MJ; Kopp, JB; Kotenko, SV; Morasso, MI; Nakabo, S; O'Neil, LJ; Wang, X; Wigerblad, G; Yu, ZX | 1 |
| Abou-Faycal, C; Aouadi, I; Armspach, JP; Bahram, S; Carapito, R; Chatelus, E; De Cauwer, A; Frisch, B; Georgel, P; Macquin, C; Mariotte, A; Paul, N; Pichot, A; Po, C; Sibilia, J | 1 |
| Álvarez-Salamero, C; Castillo-González, R; Cibrian, D; Mariblanca, IR; Navarro, MN; Pastor-Fernández, G; Pino, J | 1 |
| Chen, J; Chen, R; Chen, Y; Chen, Z; Cui, L; Diao, H; Gong, Y; Hu, Y; Shi, Y; Wang, Y; Yu, Q; Yu, Y; Zhang, X | 1 |
| Fukuyama, T; Iwano, R; Iwashita, N; Takagi, Y | 1 |
| Benedetti, M; Bueno, CA; Gentilini, MV; Marini, V; Nabaes Jodar, MS; Nebreda, AD; Salinas, FM; Shayo, C; Vázquez, L; Viegas, M | 1 |
| Du, H; Gao, L; Huang, J; Lei, L; Li, Q; Lu, J; Tan, W; Wu, Y; Xie, Y; Yao, Y; Zeng, J; Zeng, Q | 1 |
| Di, T; Fu, J; Guo, J; Li, N; Li, P; Meng, Y; Wang, Y; Zhang, L; Zhao, J | 1 |
| Ji, H; Li, X; Ma, L; Qi, R; Wang, Y; Xing, X; Xue, H | 1 |
| Cao, M; Chen, CY; Li, B; Li, H; Li, X; Ma, T; Peng, S; Sun, X; Zhou, Y; Zhu, B | 1 |
| Feng, JL; Liang, SJ; Shen, F; Shu, Y; Sun, DD; Wu, S; Xu, F; Xu, GL; Yang, Y; Zheng, QY; Zhong, Y | 1 |
| Gao, WW; Li, GQ; Liang, SJ; Sun, DD; Wang, T; Wu, S; Xu, F; Xu, GL; Yang, Y; Zheng, QY; Zhong, Y | 1 |
| Kim, BJ; Kim, CW; Kim, JH; Kim, SY; Kwon, TR; Lee, SE; Mun, SK; Na Jang, Y; Na, J | 1 |
| He, C; Kaplan, N; Peng, H; Wang, J; Wang, L; Wang, S; Yang, W | 1 |
| Brain, SD; Caton, PW; Evans, EA; Frame, J; Hannen, RF; Kodji, X; Philpott, MP; Rizvi, A; Sayers, SR; Shaikh, M; Xia, Y | 1 |
| Duan, Q; Kang, T; Liu, M; Naqvi, S; Wang, Z; Xiao, S; Zhang, F; Zhang, G; Zheng, Y | 1 |
| Fujii, K; Mizutani, Y; Saito, K; Seishima, M; Yamamoto, Y | 1 |
| Agrawal, YO; Mahajan, HS; Mahajan, UB; Ojha, S | 1 |
| Chitkara, D; Dalela, M; Mittal, A; Mohanty, S; Pukale, SS; Sharma, S; Singh, AK | 1 |
| Brennan-Crispi, D; Cotsarelis, G; Johnson, NM; Kim, HS; Leung, DH; Leung, TH; Miller, C; Rosenbach, M; Spencer, CA; Wei, JJ; Zheng, Y | 1 |
| Chen, F; Fang, H; Gao, J; Mi, J; Qi, Q; Yang, M | 1 |
| Bäumer, W; Brehm, R; Bruer, G; Gutzmer, R; Kietzmann, M; Langeheine, M; Rode, K; Rossbach, K; Schaper-Gerhardt, K; Wahle, K; Werfel, T | 1 |
| Fu, J; Li, P; Wang, Y; Zeng, Z; Zhang, L | 1 |
| Asano, Y; Fujita, H; Miyagaki, T; Morimura, S; Nakao, M; Sato, S; Shibata, S; Sugaya, M | 1 |
| Dang, EL; Fu, M; Qiao, HJ; Wang, G; Xiao, CY; Zhang, C; Zhu, ZL | 1 |
| Dinarello, CA; Fauerbye, A; Iversen, L; Johansen, C; López-Vales, R; Nielsen, AL; Rønholt, K; Vestergaard, C | 1 |
| Lou, F; Sun, Y; Wang, H | 1 |
| Chen, W; Hu, X; Jiang, J; Liu, J; Liu, W; Qie, C; Xie, X | 1 |
| Bai, C; Chen, H; He, X; Huang, Z; Lei, Y; Li, Y; Liu, Z; Sheng, L; Tang, L; Tian, X; Wei, F; Xu, X; Yang, Y; Yu, B; Zhang, B; Zhou, X | 1 |
| Choueiry, M; Fares, N; Hajal, J; Maalouly, G; Nassereddine, H; Noujeim, C; Saliba, Y; Smayra, V | 1 |
| Chen, Y; Dai, GC; Li, XQ; Tan, RX; Yan, XN; Zhou, BB | 1 |
| Bao, X; Chen, W; Ding, Y; Gao, Y; Lu, J; Peng, C; Shi, Y; Xing, K; Yi, X; Zhen, T; Zhu, S | 1 |
| Bakiri, L; Bauer, T; Bogusch, A; Borek, I; Brunner, PM; De Sa Fernandes, C; Drobits, B; Holcmann, M; Linder, M; Novoszel, P; Sibilia, M; Stary, G; Strobl, H; Stulnig, G; Tam-Amersdorfer, C; Wagner, EF; Zyulina, V | 1 |
| Devabattula, G; Gangadevi, V; Godugu, C; Pooladanda, V; Thatikonda, S | 1 |
| Cheng, J; Hu, J; Kong, H; Lu, F; Luo, J; Qu, H; Zhang, M; Zhang, Y; Zhao, Y | 1 |
| Cui, Y; Fei, WM; Guo, XD; Hao, YY; Liang, L; Zhang, C; Zhao, ZQ | 1 |
| Gruber, R; Kargarpour, Z; Miron, RJ; Nasirzade, J; Panahipour, L | 1 |
| Chung, BY; Kang, SY; Kim, HO; Kim, HR; Kim, JC; Park, CW | 1 |
| Coimbra, ES; da Silva, AD; Dib, PRB; Fung, J; Granato, JT; Kaushik, D; Macedo, GC; Petrovsky, N; Piplani, S; Salunke, DB | 1 |
| Chang, SH; Chen, YL; Hsieh, PS; Hsieh, PW; Hwang, TL; Korinek, M; Wu, YH | 1 |
| Gulino, GR; Lories, R; Martens, T; Van Mechelen, M; Vanden Berghe, P | 1 |
| Anwaar, S; Ashraf, A; Cai, P; Ganguly, D; Huang, J; Liu, B; Liu, X; Lou, J; Ni, H; Rahaman, O; Wang, L; Wen, J; Yang, CY; Zhao, J | 1 |
| Fujimoto, M; Fujisawa, Y; Ichimura, Y; Ishitsuka, Y; Kubota, N; Mizuno, S; Nakamura, Y; Okiyama, N; Saito, A; Takahashi, S; Tanaka, R; Watanabe, R | 1 |
| Estadt, SN; Gharaee-Kermani, M; Gruszka, D; Gudjonsson, JE; Kahlenberg, JM; Liu, J; Lowe, L; Reed, TJ; Theros, J; Tsoi, LC; Ward, NL; Wolf-Fortune, SJ; Xing, X | 1 |
| Abidi, A; Bériou, G; Drujont, L; Dumoutier, L; Josien, R; Kokolakis, G; Louvet, C; Martin, JC; Renauld, JC; Sabat, R; Witte-Händel, E; Wolk, K | 1 |
| Fan, S; Li, Y; Liu, W; Wang, N; Yang, X; Zheng, X; Zhu, Y | 1 |
| Ahmad, SF; Al-Harbi, NO; Attia, SM; El-Sherbeeny, AM; Fardan, AS; Ibrahim, KE; Nadeem, A | 1 |
| Fuller, SJ; Geraghty, NJ; Mansfield, KJ; Sluyter, R; Watson, D | 1 |
| Hawiger, D; Hsueh, EC; Li, L; Liu, X; Luo, H; Opejin, A; Peng, G; Wang, T; Wang, Y; Ye, J | 1 |
| Cho, S; Jin, SP; Kim, MW; Koh, SJ; Lee, DH; Park, HS; Yoon, HS; Yu, DA; Yun, HT | 1 |
| Alaverdyan, K; Chai, S; Fuchs, E; Gomez, NC; Kulukian, A; Larsen, SB; Naik, S; Polak, L; Sendoel, A; Yuan, S | 1 |
| Kim, CH; Kim, HJ; Lee, MH; Lee, YS; Won, HR | 1 |
| Bu, DF; Cao, CX; Dang, NN; Han, YF; Jiang, ZX; Liu, FT; Man, XY; Meng, Z; Shi, ZR; Tan, GZ; Wang, L; Wei, KH; Zhang, YP | 1 |
| Kim, DS; Kim, HJ; Kim, SH; Kim, TG; Lee, M; Lee, MG; Park, JY | 1 |
| Fukushige, T; Hashiguchi, T; Higashi, Y; Ibusuki, A; Kanekura, T; Yamakuchi, M | 1 |
| Ahmad, SF; Al-Harbi, NO; Attia, SM; Bakheet, SA; El-Sherbeeny, AM; Nadeem, A | 1 |
| Araújo, MM; Arruda, C; Carvalho, T; Marcato, PD; Pivetta, TP; Simões, S | 1 |
| Ma, L; Qi, R; Wang, Y; Xue, H; Yuan, L | 1 |
| Han, M; Hu, R; Huang, G; Li, H; Liu, H; Liu, X; Liu, Y; Otsu, K; Xiao, S; Zhao, W; Zheng, T | 1 |
| Palmer, G; Palomo, J; Rodriguez, E; Talabot-Ayer, D; Troccaz, S | 1 |
| Naik, S | 1 |
| Haruyama, S; Mashima, E; Nakamura, M; Ohmori, S; Okada, E; Saito-Sasaki, N; Sawada, Y; Yamaguchi, T; Yoshioka, H | 1 |
| Chandrasekharan, UM; DiCorleto, PE; Harvey, J; Husni, ME; Lax, JE; Seifarth, FG; Tytell, M | 1 |
| An, H; Dong, C; Lai, Y; Lee, YH; Liu, K; Lu, H; Shi, Y; Wang, X; Wu, Y; Xu, M; Zhang, J | 1 |
| Hung, CF; Lee, GA; Li, HJ; Wu, NL | 1 |
| Bigas, J; Boix, J; Carceller, E; Pérez, P; Sevilla, LM | 1 |
| Di, TT; Li, P; Lin, Y; Meng, YJ; Wang, MX; Wang, N; Wang, Y; Xie, XJ; Xu, XL; Zhang, L; Zhao, JX | 1 |
| Bataller, R; Caballeria, J; Cabezas, J; Crews, FT; Massey, VL; Qin, L; Sancho-Bru, P | 1 |
| Chen, G; Liao, Y; Liu, Y; Lu, Q; Shen, W; Su, Y; Wu, R; Zhang, J; Zhao, M; Zheng, M | 1 |
| Di Meglio, P; Maybury, CM; Smith, CH | 1 |
| Ahn, SH; Nguyen, LTH; Nguyen, UT; Yang, IJ | 1 |
| Arkless, KL; Aubdool, AA; Brain, SD; Caton, P; Cleary, SJ; Evans, E; Kee, Z; Kodji, X; Pitchford, SC | 1 |
| Davis, R; Griffith, AD; Hadiono, M; Pietro, A; Popkin, DL; Yang, JS; Zaidi, AK | 1 |
| Auepemkiate, S; Chorachoo, J; Furnholm, T; Johnston, A; Lambert, S; Reingold, L; Roberts, L; Voravuthikunchai, SP | 1 |
| Harada, K; Iwakura, Y; Nakae, S; Numata, T; Shimura, E; Sudo, K; Tsuboi, R; Yamaguchi, S; Yoshizaki, T | 1 |
| Brand, A; Clausen, BE; Daiber, A; Karbach, S; Klebow, S; Kolbinger, F; Kossmann, S; Münzel, T; Roohani, S; Schüler, R; Ullmann, E; Veras, FP; Waisman, A; Wenzel, P; Wild, J; Wohn, C | 1 |
| Becher, B; Cheng, P; Conrad, C; Dummer, R; Flatz, L; Hartwig, T; Navarini, A; Schlapbach, C; Schreiner, B; Yawalkar, N; Zwicky, P | 1 |
| Aihara, M; Asami, M; Komitsu, N; Takamura, N; Watanabe, Y; Yamaguchi, Y | 1 |
| Lawrence, CM; Papanikolaou, M | 1 |
| Cataisson, C; Day, CP; Flowers, B; Fraser, E; Li, L; Sanchez, V; Yuspa, SH | 1 |
| Cao, J; Chen, J; Chen, X; Fu, Y; Guo, L; Hu, J; Li, P; Li, W; Li, Y; Liu, L; Peng, J; Qiu, C; Qu, R; Vasilev, K; Wang, W; Zhao, Y; Zhou, G | 1 |
| Caruntu, C; Constantin, MM; Draghici, CC; Lisievici, CV; Lupu, M; Popa, AV; Sebe, TI; Solomon, I; Vajaitu, C; Voiculescu, VM | 1 |
| Cho, KA; Hahn, S; Kim, YH; Lee, Y; Park, JW; Park, WJ; Ryu, KH; Shin, SH; Woo, SY | 1 |
| Fujiyama, T; Funakoshi, A; Ito, T; Shimauchi, T; Tatsuno, K; Tokura, Y | 1 |
| Galiano, RD; Hong, SJ; Mao, R; Mustoe, TA; Qi, S; Xie, P; Zhao, J | 1 |
| Dong, Y; Duan, Y; Fu, D; Guo, S; Hu, H; Kalvakolanu, DV; Song, X; Tian, Z; Wang, Q | 1 |
| Challa, VS; Godugu, C; Pooladanda, V; Sunkari, S; Thatikonda, S | 1 |
| Billuart, P; Brüne, B; Burkhardt, H; da Silva, P; de Bruin, N; Elwakeel, E; Ernst, A; Han, Y; Huard, A; Lang, G; Mora, J; Parnham, MJ; Putyrski, M; Sala, C; Schmid, T; Scholz, A; Scholz, T; Schuster, C; Weigert, A; Wiechmann, S | 1 |
| Chen, HX; Dong, CZ; Du, ZY; Gu, YH; Li, PH; Zhang, WJ; Zhao, MC | 1 |
| Carstens, E; Carstens, M; Domocos, DT; Follansbee, T; Han, D; Hwang, ST; Shi, Z; Wang, B; Wu, X; Yu, S; Zhou, Y | 1 |
| Amalfitano, A; Bach, A; Crawford, RB; Kaminski, NE; Rizzo, MD; Sermet, S | 1 |
| Barber, G; Creagh, EM; Kenealy, S; Lavelle, EC; Liddicoat, A; Manils, J; Munoz-Wolf, N; Raverdeau, M | 1 |
| Chen, W; Deng, G; Gu, Z; Ji, X; Sun, Y; Wang, P; Wang, X; Zhan, T; Zheng, W | 1 |
| Chen, X; Lei, K; Li, Y; Lin, L; Liu, Y; Sun, L; Wang, D; Wang, Y; Zeng, J; Zhang, L; Zuo, D | 1 |
| Bassukas, IM; Gaitanis, G | 1 |
| Asano, Y; Ishiura, N; Kadono, T; Kamata, M; Sato, S; Shibata, S; Sugaya, M; Tada, Y; Tedder, TF; Yanaba, K | 1 |
| Hu, J; Sun, J; Zhao, Y | 1 |
| Abdulkhalek, S; Szewczuk, MR | 1 |
| Ariffin, JK; Fairlie, DP; Hohenhaus, DM; Iyer, A; Lim, J; Seow, V; Suen, JY; Sweet, MJ | 1 |
| Hu, J; Li, H; Wen, C; Yang, R; Zhao, H | 1 |
| Barnes, BJ | 1 |
| Das, MR; Dastidar, P; Deb, J; Jana, SS; Majumder, J | 1 |
| Bai, XC; Chen, TY; Feng, JY; Li, YM; Ma, J; Qin, S; Wen, J; Zheng, RC; Zhong, BL; Zhou, GB | 1 |
| Alvarez, D; Naval, E; Ordovas-Montanes, J; Paust, S; Perro, M; Riol-Blanco, L; Thiriot, A; von Andrian, UH; Wood, JN | 1 |
| Diem, S; Dy, M; Eberl, G; Latour, S; Leite-de-Moraes, MC; Massot, B; Michel, ML; Ohnmacht, C | 1 |
| Byamba, D; Jee, H; Kim, DS; Kim, DY; Kim, SH; Kim, TG; Lee, MG; Lee, SK; Park, TY; Yang, SH | 1 |
| Ahlfors, H; Di Meglio, P; Duarte, JH; Gilchrist, MJ; Hirota, K; Li, Y; Mrowietz, U; Nestle, FO; Owens, ND; Stockinger, B; Tosi, I; Villanova, F | 1 |
| Aoki, R; Kawamura, T; Matsuzawa, T; Ogawa, Y; Shimada, S | 1 |
| Boakye, CH; Godugu, C; Mendonca Faria, HA; Patel, AR; Singh, M; Somagoni, J; Zucolotto, V | 1 |
| Asahina, A; Hau, C; Kamata, M; Mitsui, A; Sato, S; Shibata, S; Tada, Y | 1 |
| Chiba, J; Kitani, H; Oshima, T; Sakuma, C; Sato, M; Takenouchi, T | 1 |
| Guo, Q; Han, Y; Tan, G; Tang, Z; Xiong, H; Xu, W; Xu, Y; Zeng, F | 1 |
| Dejager, L; Grine, L; Libert, C; Vandenbroucke, RE | 1 |
| Aluwi, MF; Mohd Amin, MC; Rehman, K; Rullah, K; Wai, LK; Zulfakar, MH | 1 |
| Cyster, JG; Gray, EE; Ramírez-Valle, F | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Al-Hosaini, KA; Al-Sharary, SD; Ansari, MA; Attia, SM; El-Sherbeeny, AM; Nadeem, A; Siddiqui, N; Zoheir, KM | 1 |
| Doble, R; Eric Blair, G; Macdonald, A; Richards, KH; Wasson, CW; Watherston, O; Wittmann, M | 1 |
| Belarif, L; Blancho, G; Cassagnau, E; Chevalier, M; Daguin, V; Hervouet, J; Le Bas-Bernardet, S; Mary, C; Minault, D; Poirier, N; Vanhove, B | 1 |
| Barrat, FJ; Elkon, KB; Fitzgerald, KA | 1 |
| Babu, RJ; Boakye, CH; Desai, PR; Kikwai, LC; Patlolla, R; Shah, PP; Singh, M | 1 |
| Amiaud, J; Bart, G; Blanchard, F; Bourreille, A; Boutet, MA; Brulin, B; Charrier, C; Gabay, C; Le Goff, B; Lecron, JC; Morel, F; Palmer, G; Penhoat, M; Rolli-Derkinderen, M; Vigne, S | 1 |
| Ban, CY; Choi, YJ; Kim, HP; Kim, J; Kim, JH; Kim, SC; Kim, SE; Kim, TG; Lee, BH; Park, J; Park, SH; Shin, EC; Song, MY; Sung, YC | 1 |
| Blackshear, PJ; Curtis, AD; Flake, GP; Hill, GD; Lai, WS; Mannie, MD; Patial, S; Stumpo, DJ | 1 |
| Grine, L; Libert, C; Vandenbroucke, RE | 1 |
| Enos, CW; Harvey, VM; Mantel, A; Trace, AP | 1 |
| Chang, KT; Choo, YK; Kim, CH; Kim, JS; Kim, SU; Lee, JM; Yoo, JK | 1 |
| Cao, T; Fang, H; Hu, J; Jin, L; Li, B; Shao, S; Wang, G; Zhang, J; Zhang, Y | 1 |
| Iversen, L; Johansen, C; Vinter, H | 1 |
| Bugara, B; Celada, A; Ferran, M; Florencia, EF; Giménez-Arnau, A; Jura, J; Lipert, B; Prens, EP; Pujol, RM; Ruiz-Romeu, E; Santamaria-Babí, LF | 1 |
| Di, T; Li, P; Liang, D; Liu, X; Wang, Y; Zhang, G; Zhao, J | 1 |
| Albanesi, C; Avigliano, L; Cavani, A; Madonna, S; Mauriello, A; Melino, G; Palombo, R; Savini, I; Terrinoni, A | 1 |
| Burden, AD; Graham, GJ; Holmes, S; Le Brocq, ML; McKimmie, CS; Schalkwijk, J; Shams, K; Singh, M; van den Bogaard, EH; Wilson, GJ | 1 |
| Fang, F; Liu, X; Mei, L; Wang, H; Zhang, S | 1 |
| Rehman, K; Zulfakar, MH | 1 |
| Amberg, N; Glitzner, E; Holcmann, M; Sibilia, M; Stulnig, G | 1 |
| Alessandrini, F; Becher, B; Freiberger, SN; Gyülveszi, G; Haak, S; Hofbauer, GF; Kishihara, K; Kulig, P; Kündig, T; Musiol, S; Pantelyushin, S; Russo, G; Sallusto, F; Schreiner, B | 1 |
| Gudjonsson, JE; Hawkes, JE; Ward, NL | 1 |
| Borek, I; Clausen, BE; Farber, JM; Hedrick, MN; Kelsall, BL; Singh, SP; Singh, TP; Wolf, P; Zhang, HH | 1 |
| Alvarez, P; Jensen, LE | 1 |
| Cho, KA; Kim, JY; Kim, YH; Lee, KH; Park, M; Ryu, KH; Woo, SY | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Almukhlafi, TS; El-Sherbeeny, AM; Nadeem, A | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alotaibi, MR; AlSaad, AM; Ansari, MA; Nadeem, A | 1 |
| Chen, Z; Du, Q; Gu, XY; Huang, M; Yin, KS; Zhou, LF | 1 |
| Carli, P; Chiarugi, A; De Giorgi, V; Maio, V; Massi, D; Nicoletti, P; Paglierani, M; Salvini, C; Santucci, M | 1 |
| Pedras-Vasconcelos, J; Puig, M; Verthelyi, D | 1 |
| Kiyota, T; Narita, M; Nishikawa, M; Takahashi, R; Takakura, Y; Toyota, H; Uno, S; Yoshida, H | 1 |
| Desai, PR; Patel, AR; Shah, PP; Singh, MS | 1 |
| Bult, H; De Meyer, GR; De Meyer, I; Martinet, W; Schrijvers, DM; Timmermans, JP | 1 |
| Moon, SD; Spencer, JM | 1 |
| Holcmann, M; Lührs, P; Meindl, S; Palamara, F; Sibilia, M; Stingl, G | 1 |
| Marincola, FM; Monsurró, V; Panelli, MC; Wang, E | 1 |
| Akira, S; Amer, A; Barchet, W; Bertin, J; Body-Malapel, M; Colonna, M; Coyle, A; Franchi, L; Grant, EP; Kanneganti, TD; Núñez, G; Ozören, N; Park, JH; Vandenabeele, P; Whitfield, J | 1 |
| Adachi, S; Fujisawa, A; Heike, T; Kambe, N; Kanazawa, N; Miyachi, Y; Nakahata, T; Nishikomori, R; Sagara, J; Saito, M; Suda, T; Tanizaki, H | 1 |
| Schön, M; Schön, MP | 1 |
| Becker, M; Bopp, T; Heib, V; Klein, M; Rechtsteiner, G; Schild, H; Schmitt, E; Stassen, M; Taube, C; Tertilt, C; Warger, T | 1 |
| Cerroni, L; Kerl, H; Kodama, K; Wolf, IH | 1 |
| Cheung, PF; Ip, WK; Lam, CW; Wong, CK | 1 |
| Bazarbachi, A; Bonnet, PA; Deleuze-Masquéfa, C; El-Hajj, H; El-Sabban, ME; Hermine, O; Kfoury, Y; Lepelletier, Y; Moarbess, G | 1 |
| Butchi, NB; Du, M; Morgan, TW; Peterson, KE; Pourciau, S | 1 |
| Castleman, WL; Kaplan, MR; Lemanske, RF; Miller, RL; Sorkness, RL; Stokes, JR; Tomai, MA | 1 |
6 review(s) available for imiquimod and Inflammation
| Article | Year |
|---|---|
Mediators of Inflammation in Topical Therapy of Skin Cancers.
Topics: Administration, Topical; Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cytokines; Diterpenes; Fluorouracil; Humans; Imiquimod; Inflammation; Melanoma; Neoplasm Metastasis; Skin; Skin Neoplasms; Toll-Like Receptor 7 | 2019 |
Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Autoimmunity; Cytosol; DNA, Viral; Endosomes; Humans; Imiquimod; Immunity, Innate; Inflammation; Lupus Erythematosus, Systemic; Nucleic Acids; Psoriasis; Signal Transduction; Toll-Like Receptors; Virus Diseases | 2016 |
Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges.
Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antimetabolites; Bleomycin; Cell Proliferation; Cicatrix, Hypertrophic; Clinical Trials as Topic; Collagen; Combined Modality Therapy; Cryotherapy; Extracellular Matrix; Fibroblasts; Fluorouracil; Glucocorticoids; Humans; Imiquimod; Inflammation; Keloid; Laser Therapy; Wound Healing | 2016 |
TLRs as therapeutic targets in CNS inflammation and infection.
Topics: Aminoquinolines; Animals; Autoimmunity; Central Nervous System Diseases; Humans; Imiquimod; Immunity, Innate; Inflammation; Toll-Like Receptors | 2009 |
A global approach to tumor immunology.
Topics: Adjuvants, Immunologic; Aminoquinolines; Cancer Vaccines; Combined Modality Therapy; Gene Expression Profiling; Genomics; Humans; Imiquimod; Immune System; Immunologic Surveillance; Immunotherapy; Inflammation; Interleukin-2; Melanoma; Neoplasms; T-Lymphocytes | 2004 |
The antitumoral mode of action of imiquimod and other imidazoquinolines.
Topics: Aminoquinolines; Animals; Antineoplastic Agents; Apoptosis; Humans; Imiquimod; Immunity, Cellular; Inflammation; Neoplasms; Quinolines; Toll-Like Receptors | 2007 |
1 trial(s) available for imiquimod and Inflammation
| Article | Year |
|---|---|
In vivo characterization of the inflammatory infiltrate and apoptotic status in imiquimod-treated basal cell carcinoma.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Apoptosis; Carcinoma, Basal Cell; CD3 Complex; CD4 Antigens; Female; Humans; Imiquimod; Inflammation; Male; Middle Aged; Ointments; Skin Neoplasms; T-Lymphocyte Subsets | 2009 |
262 other study(ies) available for imiquimod and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Topics: Animals; Cytokines; Disease Models, Animal; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; Skin | 2021 |
AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2.
Topics: Animals; Anti-Inflammatory Agents; Dogs; Drug Inverse Agonism; Female; Humans; Imiquimod; Inflammation; Isoindoles; Male; Mice, Inbred C57BL; Molecular Structure; Orphan Nuclear Receptors; Rats, Wistar; Structure-Activity Relationship; Sulfones; Th17 Cells; Thymocytes | 2021 |
Deciphering the mechanism of Fang-Ji-Di-Huang-Decoction in ameliorating psoriasis-like skin inflammation via the inhibition of IL-23/Th17 cell axis.
Topics: Animals; Copper; Drugs, Chinese Herbal; Gene Expression Regulation; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Mice; Phytotherapy; Psoriasis; Th17 Cells | 2021 |
Nintedanib ameliorates imiquimod-induced psoriasis in mice by inhibiting NF-κB and VEGFR2 signaling.
Topics: Animals; Apoptosis; Cell Proliferation; Cytokines; HaCaT Cells; Humans; Imiquimod; Indoles; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; NF-kappa B; Psoriasis; Signal Transduction; Skin; Vascular Endothelial Growth Factor Receptor-2 | 2021 |
Kynureninase contributes to the pathogenesis of psoriasis through pro-inflammatory effect.
Topics: Animals; Cell Proliferation; Humans; Hydrolases; Imiquimod; Inflammation; Keratinocytes; Mice; MicroRNAs; Psoriasis; Skin | 2022 |
IL-30 ameliorates imiquimod and K14-VEGF induced psoriasis-like disease by inhibiting both innate and adaptive immunity disorders.
Topics: Adaptive Immunity; Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Cytokines; Humans; Imiquimod; Inflammation; Interleukins; Keratin-14; Keratinocytes; Lymphocytes; Mice; Psoriasis; Signal Transduction; Vascular Endothelial Growth Factor A | 2021 |
Psoriasiform Inflammation Is Associated with Mitochondrial Fission/GDAP1L1 Signaling in Macrophages.
Topics: Animals; Female; Humans; Imiquimod; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mitochondrial Dynamics; Mitochondrial Proteins; Psoriasis; THP-1 Cells | 2021 |
Gomisin M2 alleviates psoriasis‑like skin inflammation by inhibiting inflammatory signaling pathways.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Imiquimod; Inflammation; Interferon-gamma; Keratinocytes; Lignans; Mice, Inbred C57BL; NF-kappa B; Psoriasis; Signal Transduction; STAT1 Transcription Factor; Th1 Cells; Th17 Cells; Tumor Necrosis Factor-alpha | 2021 |
MiR-193b-3p-ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes.
Topics: Animals; Antagomirs; Base Sequence; Cell Proliferation; Disease Models, Animal; Down-Regulation; Female; HaCaT Cells; Humans; Imiquimod; Inflammation; Inflammation Mediators; Keratinocytes; Male; Mice, Inbred C57BL; MicroRNAs; Models, Biological; Psoriasis; Receptor, ErbB-4; RNA, Messenger; Skin | 2021 |
PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis.
Topics: Administration, Topical; Animals; Apoptosis; Biomarkers; Cell Differentiation; Cell Movement; Cell Proliferation; Cytokines; Epithelium; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Keratinocytes; Mice, Inbred BALB C; Models, Biological; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Psoriasis; Pyridines; Quinolines; Signal Transduction; Skin; Up-Regulation | 2021 |
High salt diet impairs dermal tissue remodeling in a mouse model of IMQ induced dermatitis.
Topics: Animals; Biomarkers; Body Weight; Cell Movement; Cells, Cultured; Cytokines; Dermatitis; Dermis; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Humans; Imiquimod; Inflammation; Inflammation Mediators; Leukocytes, Mononuclear; Male; Mice, Inbred C57BL; Probiotics; Sodium Chloride, Dietary | 2021 |
IRAK4 inhibitor mitigates joint inflammation by rebalancing metabolism malfunction in RA macrophages and fibroblasts.
Topics: Adjuvants, Immunologic; Animals; Arthritis, Rheumatoid; Cells, Cultured; Fibroblasts; Humans; Imiquimod; Inflammation; Inflammation Mediators; Interleukin-1 Receptor-Associated Kinases; Macrophages; Mice; Mice, Inbred DBA | 2021 |
NF-κB1 Contributes to Imiquimod-Induced Psoriasis-Like Skin Inflammation by Inducing Vγ4
Topics: Animals; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-17; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2022 |
Lymphatic Dysfunction Exacerbates Cutaneous Tumorigenesis and Psoriasis-Like Skin Inflammation through Accumulation of Inflammatory Cytokines.
Topics: Animals; Carcinogenesis; Cytokines; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Lymphatic System; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2022 |
Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models.
Topics: Adult; Cells, Cultured; Coculture Techniques; Cytokines; Gene Expression Profiling; Gene Expression Regulation; Genetic Markers; HaCaT Cells; Humans; Imiquimod; Inflammation; Interferon-gamma; Keratinocytes; Lipopolysaccharides; Models, Biological; Psoriasis; RNA, Messenger; Serum; Tetradecanoylphorbol Acetate | 2021 |
Total withanolides ameliorates imiquimod-induced psoriasis-like skin inflammation.
Topics: Animals; Computational Biology; Gene Expression Regulation; Imiquimod; Inflammation; Interferon Inducers; Male; Mice; Mice, Inbred BALB C; Protein Interaction Maps; Psoriasis; Random Allocation; Signal Transduction; Up-Regulation; Withanolides; Zonula Occludens-1 Protein | 2022 |
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Topics: Animals; Cinnamates; Disease Models, Animal; Imiquimod; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Protective Agents; Psoriasis; RAW 264.7 Cells; Signal Transduction; Skin; Thiourea; Tumor Necrosis Factor-alpha | 2022 |
A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency.
Topics: Administration, Topical; Animals; Anthraquinones; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Emodin; HaCaT Cells; Humans; Imiquimod; Inflammation; Keratinocytes; Macrophages; Mice; Psoriasis; Rheum; Skin Absorption; Swine | 2022 |
Discovery of 2H-chromone-4-one based sulfonamide derivatives as potent retinoic acid receptor-related orphan receptor γt inverse agonists.
Topics: Amino Acid Sequence; Animals; Autoimmune Diseases; Chromones; Disease Models, Animal; Drug Development; Drug Inverse Agonism; Female; Humans; Imiquimod; Inflammation; Interleukin-17; Molecular Docking Simulation; Protein Binding; Protein Conformation; Pyrans; Receptors, Retinoic Acid; Skin; Structure-Activity Relationship; Sulfonamides; Th17 Cells | 2022 |
Topical astilbin ameliorates imiquimod-induced psoriasis-like skin lesions in SKH-1 mice via suppression dendritic cell-Th17 inflammation axis.
Topics: Animals; Cytokines; Dendritic Cells; Disease Models, Animal; Flavonols; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2022 |
Topical Treatment of Colquhounia Root Relieves Skin Inflammation and Itch in Imiquimod-Induced Psoriasiform Dermatitis in Mice.
Topics: Animals; Disease Models, Animal; Eczema; Imiquimod; Inflammation; Mice; Psoriasis; Skin | 2022 |
TNFR2 Depletion Reduces Psoriatic Inflammation in Mice by Downregulating Specific Dendritic Cell Populations in Lymph Nodes and Inhibiting IL-23/IL-17 Pathways.
Topics: Animals; Dendritic Cells; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Lymph Nodes; Mice; Mice, Inbred C57BL; Psoriasis; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2022 |
LCN2 Mediates Skin Inflammation in Psoriasis through the SREBP2‒NLRC4 Axis.
Topics: Animals; Apoptosis Regulatory Proteins; Calcium-Binding Proteins; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Keratinocytes; Lipocalin-2; Mice; Psoriasis; Skin; Sterol Regulatory Element Binding Protein 2 | 2022 |
Transcutaneous delivery of mung bean-derived nanoparticles for amelioration of psoriasis-like skin inflammation.
Topics: Animals; Disease Models, Animal; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis; Skin; Vigna | 2022 |
KdPT alleviates imiquimod-induced psoriasis-like skin lesion in mice via inhibiting proliferation and inflammation response.
Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cytokines; Disease Models, Animal; Endothelial Cells; Imiquimod; Inflammation; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Tumor Necrosis Factor-alpha | 2022 |
Selenium-Rich Yeast Peptide Fraction Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis in Mice by Inhibiting Inflammation via MAPK and NF-κB Signaling Pathways.
Topics: Animals; Cell Line; Dermatitis; Disease Models, Animal; Female; Humans; Hydrogen Peroxide; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Peptides; Psoriasis; RAW 264.7 Cells; Selenium; Signal Transduction; Skin; Yeasts | 2022 |
D-Mannose Suppresses γδ T Cells and Alleviates Murine Psoriasis.
Topics: Animals; Imiquimod; Inflammation; Intraepithelial Lymphocytes; Mannose; Mice; Psoriasis; Skin | 2022 |
Adiponectin-derived pentapeptide ameliorates psoriasiform skin inflammation by suppressing IL-17 production in γδT cells.
Topics: Adiponectin; Animals; Disease Models, Animal; Eczema; Imiquimod; Inflammation; Interleukin-17; Mice; Psoriasis; Receptors, Adiponectin; Skin | 2022 |
Human umbilical cord-derived mesenchymal stem cells ameliorate psoriasis-like dermatitis by suppressing IL-17-producing γδ T cells.
Topics: Animals; Dermatitis; Humans; Imiquimod; Inflammation; Interleukin-17; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Psoriasis; T-Lymphocytes; Umbilical Cord | 2022 |
Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells.
Topics: Animals; Imiquimod; Inflammation; Mice; Mutation; Peptides; Receptors, Antigen, T-Cell; T-Lymphocytes | 2022 |
Therapeutic effects of the extract of Sancao Formula, a Chinese herbal compound, on imiquimod-induced psoriasis via cysteine-rich protein 61.
Topics: Animals; China; Cysteine-Rich Protein 61; Disease Models, Animal; Drugs, Chinese Herbal; Imiquimod; Inflammation; Intercellular Adhesion Molecule-1; Interferon-gamma; Mice; Mice, Inbred BALB C; Psoriasis; RNA, Messenger | 2022 |
CHRNA5 Is Overexpressed in Patients with Psoriasis and Promotes Psoriasis-Like Inflammation in Mouse Models.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Humans; Imiquimod; Inflammation; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Nerve Tissue Proteins; NF-kappa B; Psoriasis; Receptors, Nicotinic | 2022 |
Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-κB Activation through Phosphorylated STAT3-TET3 Signaling.
Topics: Animals; Cysteamine; Cytokines; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; RNA, Small Interfering; Skin; STAT3 Transcription Factor; Transglutaminases | 2022 |
The Protective Role of pVHL in Imiquimod-Induced Psoriasis-like Skin Inflammation.
Topics: Animals; Dermatitis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imiquimod; Inflammation; Interleukin-17; Mice; Psoriasis; Tumor Necrosis Factor-alpha; Von Hippel-Lindau Tumor Suppressor Protein | 2022 |
Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model.
Topics: Adjuvants, Immunologic; Animals; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-17; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Psoriasis; Pyrazoles; Pyrimidines; Skin; Tumor Necrosis Factor-alpha | 2022 |
Epicutaneous Application of Imiquimod to Model Psoriasis-Like Skin Disease Induces Water-Saving Aestivation Motifs and Vascular Inflammation.
Topics: Animals; Disease Models, Animal; Estivation; Humans; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Skin Diseases; Water | 2022 |
Notch1/Hes1‑PTEN/AKT/IL‑17A feedback loop regulates Th17 cell differentiation in mouse psoriasis‑like skin inflammation.
Topics: Animals; Cell Differentiation; Dermatitis; Feedback; Imiquimod; Inflammation; Interleukin-17; Lymphadenopathy; Mechanistic Target of Rapamycin Complex 1; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Psoriasis; Skin; Splenomegaly; Th17 Cells; Transcription Factor HES-1 | 2022 |
Dietary olive oil intake aggravates psoriatic skin inflammation in mice via Nrf2 activation and polyunsaturated fatty acid imbalance.
Topics: Animals; Dermatitis; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Olive Oil; Psoriasis; Skin; Skin Diseases | 2022 |
Estradiol suppresses psoriatic inflammation in mice by regulating neutrophil and macrophage functions.
Topics: Animals; Disease Models, Animal; Estradiol; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Macrophages; Mice; Mice, Knockout; Neutrophils; Psoriasis; Receptors, Estrogen; Skin | 2022 |
Dimeric translationally controlled tumor protein-binding peptide 2 attenuates imiquimod-induced psoriatic inflammation through induction of regulatory T cells.
Topics: Animals; Cytokines; Disease Models, Animal; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Peptides; Psoriasis; Skin; T-Lymphocytes, Regulatory; Th17 Cells; Tumor Protein, Translationally-Controlled 1 | 2022 |
Sprouty1 exerts a preventive effect on the initiation of psoriasis by inhibiting innate immune antimicrobial peptide cathelicidin and immunocytes.
Topics: Animals; Antimicrobial Cationic Peptides; Antimicrobial Peptides; Cathelicidins; Disease Models, Animal; Eosine Yellowish-(YS); Hematoxylin; Humans; Imiquimod; Immunity, Innate; Inflammation; Interleukin-17; Keratinocytes; Membrane Proteins; Mice; Phosphoproteins; Psoriasis; Skin | 2022 |
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes.
Topics: Animals; Disease Models, Animal; Fatty Acid-Binding Proteins; Heterocyclic Compounds, 2-Ring; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Psoriasis; Skin; STAT3 Transcription Factor; Valine | 2022 |
Dynamic trafficking patterns of IL-17-producing γδ T cells are linked to the recurrence of skin inflammation in psoriasis-like dermatitis.
Topics: Animals; Dermatitis; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukin-17; Mice; Psoriasis; Skin; T-Lymphocytes | 2022 |
Functional Interplay between IL-9 and Peptide YY Contributes to Chronic Skin Inflammation.
Topics: Animals; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-9; Keratinocytes; Mice; Peptide YY; Psoriasis; Skin | 2022 |
Ciclopirox inhibits NLRP3 inflammasome activation via protecting mitochondria and ameliorates imiquimod-induced psoriatic inflammation in mice.
Topics: Animals; Ciclopirox; Imiquimod; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Psoriasis; Reactive Oxygen Species | 2022 |
Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Disease Models, Animal; Humans; Imiquimod; Inflammation; Keratinocytes; Macrophages; Mice; Psoriasis | 2022 |
Topical administration of the secretome derived from human amniotic epithelial cells ameliorates psoriasis-like skin lesions in mice.
Topics: Administration, Topical; Animals; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Secretome; Skin | 2022 |
Novel RNA polymerase I inhibitor CX-5461 suppresses imiquimod-induced experimental psoriasis.
Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Disease Models, Animal; Endothelial Cells; Imiquimod; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Psoriasis; RNA Polymerase I; Skin | 2023 |
Oestrogen inhibits psoriasis-like dermatitis induced by imiquimod in mice in relation to increased IL-10 producing cells despite elevated expression of IL-22, IL-23, IL-17 mRNA.
Topics: Animals; Dermatitis; Disease Models, Animal; Estrogens; Female; Imiquimod; Inflammation; Interleukin-10; Interleukin-17; Interleukin-22; Interleukin-23; Interleukins; Mice; Mice, Inbred BALB C; Psoriasis; RNA, Messenger | 2023 |
Lenalidomide attenuates IMQ-induced inflammation in a mouse model of psoriasis.
Topics: Animals; Disease Models, Animal; Imiquimod; Inflammation; Lenalidomide; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Psoriasis; Skin; Tumor Microenvironment | 2022 |
Reduction of Methyltransferase-like 3-Mediated RNA N6-Methyladenosine Exacerbates the Development of Psoriasis Vulgaris in Imiquimod-Induced Psoriasis-like Mouse Model.
Topics: Adenosine; Animals; Disease Models, Animal; Humans; Imiquimod; Inflammation; Methyltransferases; Mice; Psoriasis; RNA; RNA, Messenger | 2022 |
Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation.
Topics: Adenine; Adenosine Triphosphate; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Caspase 1; Humans; Hydrolyzable Tannins; Imiquimod; Inflammasomes; Inflammation; Interleukin-1beta; Lactate Dehydrogenases; Lipopolysaccharides; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleosides; Propidium; Pyroptosis; Reactive Oxygen Species; Uric Acid | 2022 |
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
Topics: Animals; Dermatitis; Disease Models, Animal; Guinea Pigs; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; Rabbits; Skin | 2023 |
Tryptanthrin ameliorates imiquimod-induced psoriasis in mice by suppressing inflammation and oxidative stress via NF-κB/MAPK/Nrf2 pathways.
Topics: Animals; Cytokines; Disease Models, Animal; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Psoriasis; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2023 |
Role of Type I Cannabinoid Receptor in Sensory Neurons in Psoriasiform Skin Inflammation and Pruritus.
Topics: Animals; Eczema; Imiquimod; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Psoriasis; Receptors, Cannabinoid; Sensory Receptor Cells; Substance P | 2023 |
Lipidomic profiling reveals metabolic signatures in psoriatic skin lesions.
Topics: Animals; Ceramides; Disease Models, Animal; Imiquimod; Inflammation; Keratinocytes; Lipidomics; Lipids; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2023 |
FcγRIIB inhibits inflammation in a murine model of psoriasis.
Topics: Animals; Dermatitis; Disease Models, Animal; Forkhead Transcription Factors; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2022 |
Development and evaluation emulgel for effective management of the imiquimod-induced psoriasis.
Topics: Animals; Body Weight; Disease Models, Animal; Imiquimod; Inflammation; Male; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2023 |
Comparative studies on mannan and imiquimod induced experimental plaque psoriasis inflammation in inbred mice.
Topics: Animals; Dexamethasone; Disease Models, Animal; Imiquimod; Inflammation; Mannans; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2023 |
Alleviation of imiquimod-induced psoriasis-like symptoms in Rorα-deficient mouse skin.
Topics: Animals; Imiquimod; Inflammation; Keratinocytes; Mice; Psoriasis; Skin | 2023 |
CCR4
Topics: Animals; Arthritis, Psoriatic; CD8-Positive T-Lymphocytes; Humans; Imiquimod; Inflammation; Mice; Mice, Inbred C57BL; Psoriasis; Receptors, Antigen, T-Cell; Receptors, CCR4; Skin Diseases | 2023 |
Potential skin health promoting benefits of costunolide: a therapeutic strategy to improve skin inflammation in imiquimod-induced psoriasis.
Topics: Animals; Cytokines; Dermatitis; Disease Models, Animal; Health Promotion; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Sesquiterpenes; Skin | 2023 |
Imiquimod induces skin inflammation in humanized BRGSF mice with limited human immune cell activity.
Topics: Animals; Dermatitis; Disease Models, Animal; Humans; Imiquimod; Inflammation; Mice; Psoriasis; Skin | 2023 |
PD-L1 Enhanced by cis-Urocanic Acid on Langerhans Cells Inhibits Vγ4
Topics: Animals; B7-H1 Antigen; Dermatitis; Humans; Imiquimod; Inflammation; Interleukin-23; Langerhans Cells; Mice; Psoriasis; Ultraviolet Rays; Urocanic Acid | 2023 |
Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.
Topics: Adenylyl Cyclases; Animals; Humans; Imiquimod; Inflammation; Interleukin-17; Mice; Mice, Knockout; Microbiota; Psoriasis; T-Lymphocytes, Regulatory | 2023 |
Fufang Shengdi mixture alleviates psoriasis-like skin inflammation via promoting Annexin-A proteins expression.
Topics: Animals; Annexins; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Skin Diseases; Tumor Necrosis Factor-alpha | 2023 |
Isostearic acid is an active component of imiquimod formulations used to induce psoriaform disease models.
Topics: Animals; Cytokines; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Skin; Toll-Like Receptor 7 | 2023 |
The Impact of Proinflammatory Cytokines and Imiquimod on GLUT1 in HaCaT Keratinocytes - a Potential Anti-Psoriatic Therapeutic Target?
Topics: Animals; Cytokines; Disease Models, Animal; Glucose Transporter Type 1; Humans; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Tumor Necrosis Factor-alpha | 2023 |
Palbociclib blocks neutrophilic phosphatidylinositol 3-kinase activity to alleviate psoriasiform dermatitis.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis; Disease Models, Animal; Humans; Imiquimod; Inflammation; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Psoriasis | 2023 |
Treg cells require Izumo1R to regulate γδT cell-driven inflammation in the skin.
Topics: Animals; Dermatitis; Imiquimod; Inflammation; Mice; Psoriasis; Receptors, Cell Surface; Skin; Skin Diseases; T-Lymphocytes, Regulatory | 2023 |
Topics: Caspase 1; Caspases; Cornus; Dermatitis; DNA-Binding Proteins; HEK293 Cells; Humans; Imiquimod; Inflammasomes; Inflammation; Interleukin-1beta; NLR Family, Pyrin Domain-Containing 3 Protein; Plant Extracts; Psoriasis; Seeds | 2023 |
Specific Activation of CB2R Ameliorates Psoriasis-Like Skin Lesions by Inhibiting Inflammation and Oxidative Stress.
Topics: Animals; Cytokines; Disease Models, Animal; Imiquimod; Inflammation; Kelch-Like ECH-Associated Protein 1; Keratinocytes; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Oxidative Stress; Psoriasis; Skin; Skin Diseases | 2023 |
Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis.
Topics: Animals; Disease Models, Animal; Eukaryotic Initiation Factor-4E; Humans; Hyperplasia; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Tumor Necrosis Factor-alpha | 2023 |
Soluble adenylyl cyclase contributes to imiquimod-mediated inflammation and is a potential therapeutic target in psoriasis.
Topics: Adenylyl Cyclases; Animals; Disease Models, Animal; Eczema; Imiquimod; Inflammation; Mice; Psoriasis; Skin; Th17 Cells | 2023 |
Etanercept ameliorates psoriasis progression through regulating high mobility group box 1 pathway.
Topics: Animals; Disease Models, Animal; Etanercept; HMGB1 Protein; Imiquimod; Inflammation; Keratinocytes; Lipopolysaccharides; Mice; Psoriasis; Receptor for Advanced Glycation End Products | 2023 |
Piperine ameliorates psoriatic skin inflammation by inhibiting the phosphorylation of STAT3.
Topics: Alkaloids; Animals; Cytokines; Dermatitis; Disease Models, Animal; Humans; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Phosphorylation; Psoriasis; Skin; STAT3 Transcription Factor | 2023 |
Topics: Animals; Cytokines; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukins; Keratinocytes; Mice; Psoriasis; Skin; TEA Domain Transcription Factors; Th1 Cells; Th17 Cells; Transcription Factor AP-2 | 2023 |
SIRT3 alleviates imiquimod-induced psoriatic dermatitis through deacetylation of XBP1s and modulation of TLR7/8 inducing IL-23 production in macrophages.
Topics: Animals; Dermatitis; Imiquimod; Inflammation; Interleukin-23; Macrophages; Mice; Psoriasis; Sirtuin 3; Toll-Like Receptor 7; X-Box Binding Protein 1 | 2023 |
Procyanidin B2 3,3''-di-O-gallate ameliorates imiquimod-induced skin inflammation by suppressing TLR7 signaling through the inhibition of endosomal acidification in dendritic cells.
Topics: Animals; Cytokines; Dendritic Cells; Dermatitis; Endosomes; Hydrogen-Ion Concentration; Imiquimod; Inflammation; Mice; Toll-Like Receptor 7 | 2023 |
Centella asiatica alleviates psoriasis through JAK/STAT3-mediated inflammation: An in vitro and in vivo study.
Topics: Animals; Antioxidants; Centella; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; Skin | 2023 |
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
Topics: Animals; Cell Proliferation; Cytokines; Dermatitis; DNA; Imiquimod; Inflammation; Interleukin-22; Keratinocytes; Mice; Protein Kinases; Psoriasis; Skin | 2023 |
PARP2 promotes inflammation in psoriasis by modulating estradiol biosynthesis in keratinocytes.
Topics: Animals; Aromatase; Dermatitis; Disease Models, Animal; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Psoriasis; RNA, Messenger; Skin | 2023 |
Effect and mechanism of hydrogen-rich bath on mice with imiquimod-induced psoriasis.
Topics: Animals; Disease Models, Animal; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Water | 2023 |
RasGRP1 influences imiquimod-induced psoriatic inflammation via T-cell activation in mice.
Topics: Animals; Disease Models, Animal; Humans; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Vascular Endothelial Growth Factor A | 2023 |
Gentiopicroside-Loaded Chitosan Nanoparticles Inhibit TNF-α-Induced Proliferation and Inflammatory Response in HaCaT Keratinocytes and Ameliorate Imiquimod-Induced Dermatitis Lesions in Mice.
Topics: Animals; Cell Proliferation; Chitosan; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-17; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2023 |
Evidence on the therapeutic role of thiolutin in imiquimod-induced psoriasis-like skin inflammation in mice.
Topics: Animals; Dermatitis; Forkhead Transcription Factors; Imiquimod; Inflammasomes; Inflammation; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Psoriasis | 2023 |
Characterization and active component identification of Premna herbacea roxb. root extract reveals anti-inflammatory effect and amelioration of imiquimod induced psoriasis via modulation of macrophage inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Humans; Imiquimod; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Plant Extracts; Psoriasis; Skin | 2023 |
Forward genetics and functional analysis highlight Itga11 as a modulator of murine psoriasiform dermatitis.
Topics: Animals; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Integrin alpha Chains; Mice; Psoriasis; Skin | 2023 |
Tranexamic acid improves psoriasis-like skin inflammation: Evidence from in vivo and in vitro studies.
Topics: Animals; Dermatitis; Disease Models, Animal; Humans; Imiquimod; Inflammasomes; Inflammation; Interleukin-17; Keratin-17; Keratinocytes; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Psoriasis; Skin; Tranexamic Acid | 2023 |
Curcumin alleviates imiquimod-induced psoriasis-like inflammation and regulates gut microbiota of mice.
Topics: Animals; Curcumin; Dermatitis; Gastrointestinal Microbiome; Imiquimod; Inflammation; Interleukin-23; Mice; Tumor Necrosis Factor-alpha | 2023 |
Gasdermin D-mediated keratinocyte pyroptosis as a key step in psoriasis pathogenesis.
Topics: Animals; Dermatitis; Disulfiram; Gasdermins; Imiquimod; Inflammation; Keratinocytes; Ki-67 Antigen; Mice; Psoriasis; Pyroptosis | 2023 |
Di-(2-ethylhexyl) phthalate aggravates psoriasis-like skin lesions: In vitro and in vivo evaluation.
Topics: Animals; Diethylhexyl Phthalate; Humans; Imiquimod; Inflammation; Mice; p38 Mitogen-Activated Protein Kinases; Psoriasis; Skin; Skin Diseases | 2023 |
Topical anti-TNF-a ssDNA aptamer decreased the imiquimod induced psoriatic inflammation in BALB/c mice.
Topics: Animals; Disease Models, Animal; DNA, Single-Stranded; Imiquimod; Inflammation; Interleukin-17; Mice; Mice, Inbred BALB C; Psoriasis; RNA, Messenger; Skin; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2023 |
Development of a Deep Eutectic Solvent-Assisted Kaempferol Hydrogel: A Promising Therapeutic Approach for Psoriasis-like Skin Inflammation.
Topics: Animals; Antioxidants; Deep Eutectic Solvents; Disease Models, Animal; Hydrogels; Imiquimod; Inflammation; Kaempferols; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2023 |
Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced psoriasis-like skin lesions.
Topics: Humans; Imiquimod; Inflammation; Lipids; Nanoparticles; Noscapine; Psoriasis; Skin | 2023 |
Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation.
Topics: Animals; Antibodies, Neutralizing; CD4-Positive T-Lymphocytes; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Interleukin-7; Lymph Nodes; Lymphatic Vessels; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Oxazolone; Psoriasis; Receptors, Interleukin-7; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2019 |
Kaempferol attenuates imiquimod-induced psoriatic skin inflammation in a mouse model.
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukin-17; Interleukin-6; Kaempferols; Mice, Inbred BALB C; Psoriasis; Signal Transduction; Skin | 2019 |
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
Topics: A549 Cells; Animals; Antibodies, Blocking; Antibodies, Monoclonal; Cell Line, Tumor; Disease Models, Animal; HEK293 Cells; Humans; Imiquimod; Inflammation; Interleukin-1; Interleukin-1 Receptor Accessory Protein; Interleukin-1beta; Interleukin-33; Male; Mice; Mice, Inbred C57BL; Ovalbumin; Peritonitis; Pneumonia; Psoriasis; Signal Transduction; Uric Acid | 2019 |
Kan-Lu-Hsiao-Tu-Tan, a traditional Chinese medicine formula, inhibits human neutrophil activation and ameliorates imiquimod-induced psoriasis-like skin inflammation.
Topics: Animals; Cells, Cultured; Drugs, Chinese Herbal; Humans; Imiquimod; Inflammation; Male; Medicine, Chinese Traditional; Mice; Neutrophil Activation; Neutrophils; Psoriasis | 2020 |
Biological depletion of neutrophils attenuates pro-inflammatory markers and the development of the psoriatic phenotype in a murine model of psoriasis.
Topics: Animals; Biomarkers; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Humans; Imiquimod; Inflammation; Leukocyte Reduction Procedures; Mice; Mice, Inbred BALB C; Neutrophils; Phenotype; Psoriasis | 2020 |
D-Pinitol Ameliorates Imiquimod-Induced PsoriasisLike Skin Inflammation in a Mouse Model via the NF-κB Pathway.
Topics: Animals; Anti-Inflammatory Agents; Imiquimod; Inflammation; Inositol; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis | 2019 |
Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis.
Topics: Animals; Cell Line; Cell Proliferation; Cytokines; Disease Models, Animal; Gene Expression; Humans; Imiquimod; Inflammation; Interleukin-6; Keratinocytes; Male; Mice; Mice, Knockout; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Psoriasis; RNA, Messenger; Severity of Illness Index; Th17 Cells; TRPV Cation Channels | 2020 |
Taxifolin attenuates IMQ-induced murine psoriasis-like dermatitis by regulating T helper cell responses via Notch1 and JAK2/STAT3 signal pathways.
Topics: Animals; Cell Line; Cell Proliferation; Cyclosporine; Cytokines; Dermatitis; Humans; Imiquimod; Inflammation; Janus Kinase 2; Keratinocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Models, Animal; Psoriasis; Quercetin; Receptor, Notch1; Signal Transduction; Skin; STAT3 Transcription Factor; T-Lymphocytes; Transcription Factors | 2020 |
Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation.
Topics: Animals; Apoptosis; Cell Proliferation; Chemokines; Dioxolanes; Epidermis; Epigenesis, Genetic; HaCaT Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Imiquimod; Inflammation; Keratin-17; Keratinocytes; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Models, Biological; Phosphorylation; Protein Binding; Psoriasis; RAW 264.7 Cells; Skin; STAT3 Transcription Factor | 2020 |
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Regulates Epidermal Keratinization under Psoriatic Skin Inflammation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Chimera; Epidermis; Female; Homeostasis; Humans; Imiquimod; Immunohistochemistry; Inflammation; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Parakeratosis; Psoriasis; Skin | 2020 |
4-1BBL Regulates the Polarization of Macrophages, and Inhibition of 4-1BBL Signaling Alleviates Imiquimod-Induced Psoriasis.
Topics: 4-1BB Ligand; Animals; Cell Line; Female; Imiquimod; Inflammation; Interleukin-17; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Psoriasis; RAW 264.7 Cells; Signal Transduction; Skin; T-Lymphocytes, Regulatory | 2020 |
Chrysin alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides.
Topics: Animals; Antimicrobial Cationic Peptides; Chemokine CCL20; Disease Models, Animal; Down-Regulation; Epidermis; Flavonoids; Humans; Hyperplasia; Imiquimod; Inflammation; Interleukin-17; Interleukin-22; Interleukins; Keratinocytes; Male; MAP Kinase Signaling System; Mice, Inbred BALB C; NF-kappa B; Phosphorylation; Psoriasis; RNA, Messenger; Skin; Tumor Necrosis Factor-alpha | 2020 |
Keratinocyte interleukin-36 receptor expression orchestrates psoriasiform inflammation in mice.
Topics: Animals; Cytokines; Dermatitis; Female; Humans; Imiquimod; Inflammation; Intraepithelial Lymphocytes; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Psoriasis; Receptors, Interleukin-1; Skin | 2020 |
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.
Topics: Animals; B-Lymphocytes; Cell Line; Gene Deletion; Humans; Imiquimod; Inflammation; Interferon Inducers; Interferon Lambda; Interferon Type I; Interferons; Keratinocytes; Lupus Erythematosus, Systemic; Mesangial Cells; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, Interferon; Signal Transduction; Toll-Like Receptor 7 | 2020 |
A mouse model of MSU-induced acute inflammation
Topics: Acute Disease; Adjuvants, Immunologic; Administration, Topical; Animals; Antioxidants; Cytokines; Disease Models, Animal; Gout; Imiquimod; Inflammation; Injections, Subcutaneous; Interleukin-1beta; Magnetic Resonance Imaging; Mice; Mice, Knockout; Uric Acid | 2020 |
IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics.
Topics: Animals; Cell Movement; Imiquimod; Inflammation; Interleukin-23 Subunit p19; Janus Kinase 2; Mice, Inbred C57BL; Mice, Transgenic; Myosin Light Chains; Phosphorylation; Proteomics; Receptors, Interleukin; rho-Associated Kinases; Serine; Signal Transduction; Th17 Cells | 2020 |
Interleukin-33 alleviates psoriatic inflammation by suppressing the T helper type 17 immune response.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Humans; Imiquimod; Immune Tolerance; Immunity, Cellular; Inflammation; Interleukin-17; Interleukin-33; Mice; Mice, Inbred C57BL; Psoriasis; Skin; Th17 Cells | 2020 |
Estrogen receptor α activation aggravates imiquimod-induced psoriasis-like dermatitis in mice by enhancing dendritic cell interleukin-23 secretion.
Topics: Animals; Dendritic Cells; Estrogen Receptor alpha; Humans; Imiquimod; Inflammation; Interleukin-23; Male; Mice; Models, Animal; Pruritus; Psoriasis | 2020 |
Imiquimod suppresses respiratory syncytial virus (RSV) replication via PKA pathway and reduces RSV induced-inflammation and viral load in mice lungs.
Topics: A549 Cells; Animals; Antiviral Agents; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Cytokines; Disease Models, Animal; Epithelial Cells; Female; Humans; Imiquimod; Inflammation; Lung; Mice; Mice, Inbred BALB C; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Signal Transduction; Viral Load; Virus Replication | 2020 |
Ozone Therapy Attenuates NF-κB-Mediated Local Inflammatory Response and Activation of Th17 Cells in Treatment for Psoriasis.
Topics: Administration, Topical; Animals; Baths; CD4-Positive T-Lymphocytes; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; NF-kappa B; Oils; Ozone; Psoriasis; Severity of Illness Index; Th17 Cells; Toll-Like Receptor 2 | 2020 |
Stress aggravates and prolongs imiquimod-induced psoriasis-like epidermal hyperplasis and IL-1β/IL-23p40 production.
Topics: Animals; Anxiety; Dendritic Cells; Dermatitis; Emotions; Epidermis; Hyperplasia; Imiquimod; Inflammation; Interleukin-12 Subunit p40; Interleukin-1beta; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Nociceptors; Psoriasis; Receptors, Neurokinin-1; Stress, Psychological; Substance P; Up-Regulation | 2020 |
Notch-Hes1 Signaling Regulates IL-17A
Topics: Animals; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Imiquimod; Inflammation; Interleukin-17; Male; Mice; Mice, Inbred BALB C; Psoriasis; Receptors, Notch; Signal Transduction; Skin; Spleen; T-Lymphocytes; Th17 Cells; Transcription Factor HES-1 | 2020 |
Recombinant programmed cell death 1 inhibits psoriatic inflammation in imiquimod‑treated mice.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Imiquimod; Inflammation; Male; Mice; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor; Psoriasis; Reverse Transcriptase Polymerase Chain Reaction | 2020 |
Complement component 3 prevents imiquimod-induced psoriatic skin inflammation by inhibiting apoptosis in mice.
Topics: Animals; Apoptosis; Complement C3; Cytokines; Female; Imiquimod; Inflammation; Interleukin-17; Male; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Skin; T-Lymphocytes | 2020 |
C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from γδ-T cells.
Topics: Animals; Cytokines; Down-Regulation; Female; Gene Expression; Imiquimod; Inflammation; Interleukin-17; Intraepithelial Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Psoriasis; Receptor, Anaphylatoxin C5a; Signal Transduction; Skin | 2020 |
310 nm UV-LEDs attenuate imiquimod-induced psoriasis-like skin lesions in C57BL/6 mice and inhibit IL-22-induced STAT3 expression in HaCaT cells.
Topics: Animals; Antineoplastic Agents; HaCaT Cells; Humans; Imiquimod; Inflammation; Interleukin-22; Interleukins; Mice; Mice, Inbred C57BL; Psoriasis; Skin; STAT3 Transcription Factor; Ultraviolet Rays | 2020 |
Autophagy plays a positive role in induction of epidermal proliferation.
Topics: Animals; Autophagy; Cell Cycle; Cell Proliferation; Cells, Cultured; Epidermis; Gene Expression; Humans; Hyperplasia; Imiquimod; Inflammation; Keratinocytes; Mice; Signal Transduction; Skin | 2020 |
Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome.
Topics: Animals; Cell Proliferation; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Imiquimod; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Prediabetic State; Psoriasis; Skin | 2020 |
Cytotoxicity of Saikosaponin A targets HEKa cell through apoptosis induction by ROS accumulation and inflammation suppression via NF-κB pathway.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Humans; Imiquimod; Immunosuppression Therapy; Inflammation; Keratinocytes; Mice; NF-kappa B; Oleanolic Acid; Reactive Oxygen Species; Saponins; Signal Transduction | 2020 |
Topics: Animals; Cytokines; Dermatitis; Female; Gene Expression Regulation; Imiquimod; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interleukin-17; Interleukin-23 Subunit p19; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Skin; Tumor Necrosis Factor-alpha | 2020 |
Methotrexate-Loaded Nanostructured Lipid Carrier Gel Alleviates Imiquimod-Induced Psoriasis by Moderating Inflammation: Formulation, Optimization, Characterization, In-Vitro and In-Vivo Studies.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Catalase; Cytokines; Drug Carriers; Drug Compounding; Drug Liberation; Gels; Glutathione; Humans; Imiquimod; Inflammation; Lipids; Malondialdehyde; Methotrexate; Mice, Inbred BALB C; Nanostructures; Organ Size; Psoriasis; Superoxide Dismutase | 2020 |
Multi-component clobetasol-loaded monolithic lipid-polymer hybrid nanoparticles ameliorate imiquimod-induced psoriasis-like skin inflammation in Swiss albino mice.
Topics: Animals; Clobetasol; Imiquimod; Inflammation; Lipids; Mice; Nanoparticles; Polymers; Psoriasis | 2020 |
Activation of TRPA1 nociceptor promotes systemic adult mammalian skin regeneration.
Topics: Adjuvants, Immunologic; Animals; Cicatrix; Female; Imiquimod; Inflammation; Intraepithelial Lymphocytes; Male; Mice, Inbred C57BL; Mice, SCID; Mice, Transgenic; Regeneration; Skin; Skin Physiological Phenomena; TRPA1 Cation Channel; Wound Healing | 2020 |
Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Cell Proliferation; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Rabbits; Umbelliferones | 2020 |
Histamine 2 Receptor Agonism and Histamine 4 Receptor Antagonism Ameliorate Inflammation in a Model of Psoriasis.
Topics: Animals; Disease Models, Animal; Histamine; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin | 2020 |
4'-O-β-D-glucosyl-5-O-methylvisamminol ameliorates imiquimod-induced psoriasis-like dermatitis and inhibits inflammatory cytokines production by suppressing the NF-κB and MAPK signaling pathways.
Topics: Animals; Chromones; Cytokines; Dermatitis; Glucosides; Imiquimod; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis | 2020 |
TLR2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Skin Inflammation through Decrease in Regulatory T Cells and Impaired IL-10 Production.
Topics: Animals; Imiquimod; Inflammation; Interleukin-10; Mice; Mice, Knockout; Psoriasis; Skin; T-Lymphocytes, Regulatory; Toll-Like Receptor 2 | 2020 |
Small interfering RNA targeting of keratin 17 reduces inflammation in imiquimod-induced psoriasis-like dermatitis.
Topics: Animals; Dermatitis; Disease Models, Animal; Female; Humans; Imiquimod; Inflammation; Keratin-17; Mice; Mice, Inbred BALB C; Psoriasis; RNA, Small Interfering; Skin | 2020 |
IL-37 Expression Is Downregulated in Lesional Psoriasis Skin.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation; Female; Humans; Imiquimod; Inflammation; Interleukin-1; Interleukin-17; Keratinocytes; Mice; Mice, Inbred C57BL; Psoriasis; Tumor Necrosis Factor-alpha | 2020 |
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
Topics: Aminoquinolines; Animals; Cytokines; Dermis; Disease Models, Animal; Epidermal Cells; Epidermis; Flow Cytometry; Imiquimod; Inflammation; Leukemic Infiltration; Mice; Psoriasis; Skin | 2020 |
M351-0056 is a novel low MW compound modulating the actions of the immune-checkpoint protein VISTA.
Topics: Animals; Cytokines; Dermatitis; Imiquimod; Immune Checkpoint Proteins; Inflammation; Ligands; Lymphocyte Activation; Membrane Proteins; Mice | 2021 |
Pentacyclic triterpene compounds from loquat leaves reduce skin inflammation and epidermal hyperplasia in psoriasis via inhibiting the Th17 cells.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Cell Survival; Cytokines; Disease Models, Animal; Epidermis; Eriobotrya; Humans; Hyperplasia; Imiquimod; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Pentacyclic Triterpenes; Plant Leaves; Psoriasis; Th17 Cells | 2021 |
New insights in gut-liver axis in wild-type murine imiquimod-induced lupus.
Topics: Animals; Feces; Female; Imiquimod; Inflammation; Leukocyte L1 Antigen Complex; Liver; Lupus Erythematosus, Systemic; Mice; Mice, Inbred C57BL; NF-kappa B; Tight Junctions; Toll-Like Receptor 4 | 2021 |
Abietic acid ameliorates psoriasis-like inflammation and modulates gut microbiota in mice.
Topics: Abietanes; Animals; Anti-Inflammatory Agents; Correlation of Data; Cytokines; Gastrointestinal Microbiome; Imiquimod; Inflammation; Male; Medicine, Chinese Traditional; Mice, Inbred BALB C; Psoriasis; RNA, Ribosomal, 16S; T-Lymphocytes, Regulatory; Th17 Cells | 2021 |
Inhibition of phospholipases suppresses progression of psoriasis through modulation of inflammation.
Topics: Animals; Antigens, CD1; Cell Line; Disease Models, Animal; Gene Expression Regulation; Group IV Phospholipases A2; Humans; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Male; Mice, Inbred BALB C; Psoriasis; RNA, Small Interfering | 2021 |
Psoriatic skin inflammation is promoted by c-Jun/AP-1-dependent CCL2 and IL-23 expression in dendritic cells.
Topics: Animals; Dendritic Cells; Imiquimod; Inflammation; Interleukin-23; Mice; Transcription Factor AP-1 | 2021 |
Selenium nanoparticles produce a beneficial effect in psoriasis by reducing epidermal hyperproliferation and inflammation.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line; Glycogen Synthase Kinase 3 beta; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Nanoparticles; Oxidation-Reduction; Phosphorylation; Psoriasis; Reactive Oxygen Species; Selenium; STAT3 Transcription Factor | 2021 |
Green Phellodendri Chinensis Cortex-based carbon dots for ameliorating imiquimod-induced psoriasis-like inflammation in mice.
Topics: Animals; Carbon; Cytokines; Disease Models, Animal; Imiquimod; Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Psoriasis; RAW 264.7 Cells; Skin | 2021 |
Improved imiquimod-induced psoriasis like dermatitis using microneedles in mice.
Topics: Administration, Cutaneous; Animals; Cytokines; Dermatitis; Disease Models, Animal; Drug Delivery Systems; Female; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Needles; Pharmaceutical Preparations; Polyesters; Polymers; Psoriasis; Skin; Swine | 2021 |
Liquid PRF Reduces the Inflammatory Response and Osteoclastogenesis in Murine Macrophages.
Topics: Animals; Imiquimod; Inflammation; Inflammation Mediators; Lactoferrin; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Mice; Osteoclasts; Osteogenesis; Phenotype; Platelet-Rich Plasma; Poly I-C; RAW 264.7 Cells; Toll-Like Receptor 3; Toll-Like Receptor 7 | 2021 |
Rapamycin Alleviates 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Aggravated Dermatitis in Mice with Imiquimod-Induced Psoriasis-Like Dermatitis by Inducing Autophagy.
Topics: Animals; Autophagy; Cell Differentiation; Cells, Cultured; Cytochrome P-450 CYP1A1; Dermatitis; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; NADPH Oxidase 4; NF-E2-Related Factor 2; Polychlorinated Dibenzodioxins; Psoriasis; Receptors, Aryl Hydrocarbon; Sirolimus | 2021 |
Toll-like receptor-7/8 agonist kill Leishmania amazonensis by acting as pro-oxidant and pro-inflammatory agent.
Topics: Animals; Antiprotozoal Agents; Cytokines; Female; Humans; Imidazoles; Imiquimod; Inflammation; Leishmania; Leishmaniasis; Macrophages, Peritoneal; Mice, Inbred BALB C; Nitric Oxide; Reactive Oxygen Species; Toll-Like Receptor 7; Toll-Like Receptor 8 | 2021 |
Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo.
Topics: Adult; Animals; Cell Line; Cells, Cultured; Female; HEK293 Cells; Humans; Imiquimod; Inflammation; Male; Mice; Mice, Inbred BALB C; Neutrophils; Psoriasis; Receptors, Formyl Peptide; Triterpenes; Ursolic Acid; Young Adult | 2021 |
Impact of barrier tissue inflammation and physical activity on joint homeostasis in mice.
Topics: Animals; Disease Models, Animal; Homeostasis; Humans; Imiquimod; Inflammation; Male; Mice; Mice, Inbred C57BL; Psoriasis | 2022 |
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Chemokine CCL2; Cytokines; Dendritic Cells; Dermatitis; Endoribonucleases; Epigenomics; Humans; Imiquimod; Inflammation; Interleukin-6; Macrophages; Mice; Mice, Knockout; Myeloid Cells; Psoriasis; Ribonucleases; Skin; Tumor Necrosis Factor-alpha | 2021 |
Differential Involvement of Programmed Cell Death Ligands in Skin Immune Responses.
Topics: Animals; Antigen Presentation; B7-H1 Antigen; Calcitriol; Cells, Cultured; Cytokines; Dendritic Cells; Dermatitis, Atopic; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Humans; Imiquimod; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Ligand 2 Protein; Psoriasis; Skin; Th1 Cells; Th17 Cells; Th2 Cells | 2022 |
IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Female; Humans; Imiquimod; Inflammation; Interferon Type I; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Skin; Up-Regulation | 2022 |
Limited Presence of IL-22 Binding Protein, a Natural IL-22 Inhibitor, Strengthens Psoriatic Skin Inflammation.
Topics: Adult; Aged; Aminoquinolines; Animals; Antibodies, Blocking; Cells, Cultured; Female; Gene Knockout Techniques; Humans; Imiquimod; Inflammation; Interleukin-22; Interleukins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Middle Aged; Psoriasis; Rats; Rats, Sprague-Dawley; Receptors, Interleukin; Signal Transduction; Skin; Young Adult | 2017 |
Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation.
Topics: Aminoquinolines; Animals; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique; Imidazoles; Imiquimod; Immunity, Innate; Immunosuppressive Agents; Inflammasomes; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligodeoxyribonucleotides; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9; Zymosan | 2017 |
IL-17A causes depression-like symptoms via NFκB and p38MAPK signaling pathways in mice: Implications for psoriasis associated depression.
Topics: Aminoquinolines; Animals; Brain; Depression; Depressive Disorder, Major; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukin-17; MAP Kinase Signaling System; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Psoriasis | 2017 |
The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Cell Line; Female; Humans; Imiquimod; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Receptors, Purinergic P2X7 | 2017 |
TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy.
Topics: Aminoquinolines; Animals; Autoimmunity; Cell Differentiation; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Imiquimod; Immunotherapy; Inflammation; Interleukin-17; Membrane Glycoproteins; Mice; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Th1 Cells; Th17 Cells; Toll-Like Receptor 7 | 2017 |
Imiquimod-applied Interleukin-10 deficient mice better reflects severe and persistent psoriasis with systemic inflammatory state.
Topics: Adjuvants, Immunologic; Animals; Body Weight; Cytokines; Dermatitis; Disease Models, Animal; Epidermis; Imiquimod; Inflammation; Interleukin-10; Interleukin-17; Keratinocytes; Leukocyte Common Antigens; Male; Mice; Mice, Inbred C57BL; Organ Size; Psoriasis; RNA, Messenger; Skin; Spleen; Time Factors | 2018 |
Inflammatory memory sensitizes skin epithelial stem cells to tissue damage.
Topics: Aminoquinolines; Animals; Autoimmune Diseases; Caspase 1; Cell Lineage; Chromatin; DNA-Binding Proteins; Epigenesis, Genetic; Epithelial Cells; Female; Imiquimod; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Mice; Neoplasms; Regeneration; Skin; Stem Cells; Stress, Physiological; T-Lymphocytes; Wound Healing | 2017 |
Non-thermal atmospheric plasma ameliorates imiquimod-induced psoriasis-like skin inflammation in mice through inhibition of immune responses and up-regulation of PD-L1 expression.
Topics: Animals; B7-H1 Antigen; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Cell Differentiation; Dendritic Cells; Disease Models, Animal; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Lymph Nodes; Mice; Plasma Gases; Psoriasis; Th17 Cells | 2017 |
Decrease of galectin-3 in keratinocytes: A potential diagnostic marker and a critical contributor to the pathogenesis of psoriasis.
Topics: Animals; Biomarkers; Cells, Cultured; Disease Models, Animal; Disease Progression; Galectin 3; Humans; Imiquimod; Inflammation; Keratinocytes; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Phenylurea Compounds; Psoriasis; Receptors, Interleukin-8B; Signal Transduction; Skin | 2018 |
Interleukin-21 receptor signalling is not critically required for imiquimod-induced psoriasiform dermatitis in mice.
Topics: Animals; CD4-Positive T-Lymphocytes; Dermatitis; Imiquimod; Inflammation; Interferon Inducers; Interleukin-21 Receptor alpha Subunit; Interleukin-23 Subunit p19; Intraepithelial Lymphocytes; Mice; Mice, Knockout; Mice, Transgenic; Psoriasis; Receptors, Interleukin-21; Signal Transduction | 2018 |
High-fat diet exacerbates imiquimod-induced psoriasis-like dermatitis in mice.
Topics: Animals; Body Weight; Cholesterol; Cytokines; Dermatitis; Diet, High-Fat; Disease Models, Animal; Disease Progression; Hyperlipidemias; Imiquimod; Inflammasomes; Inflammation; Male; Mice; Mice, Inbred C57BL; Neutrophils; Psoriasis; Skin | 2018 |
Systemic inflammation in asocial BTBR T
Topics: Adaptive Immunity; Animals; Arthritis, Psoriatic; Autism Spectrum Disorder; Disease Models, Animal; Disease Susceptibility; Imiquimod; Immunity, Innate; Inflammation; Male; Membrane Glycoproteins; Mice, Inbred C57BL; Skin; Social Behavior; Species Specificity; Th17 Cells; Toll-Like Receptor 7 | 2018 |
Development of nanoparticles from natural lipids for topical delivery of thymol: Investigation of its anti-inflammatory properties.
Topics: Administration, Topical; Aminoquinolines; Animals; Anti-Inflammatory Agents; Antioxidants; Betamethasone; Cell Death; Cell Line; Cell Survival; Disease Models, Animal; Drug Compounding; Drug Liberation; Ear; Edema; Humans; Imiquimod; Inflammation; Keratinocytes; Lipids; Mice, Inbred BALB C; Nanoparticles; Particle Size; Permeability; Psoriasis; Rheology; Skin; Sus scrofa; Thymol | 2018 |
Effect of γ-secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis-like skin inflammation.
Topics: Amyloid Precursor Protein Secretases; Animals; Cell Differentiation; Dipeptides; Down-Regulation; Imiquimod; Inflammation; Interleukin-17; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Notch; RNA, Messenger; Skin; Splenomegaly; Th17 Cells | 2018 |
p38α signaling in Langerhans cells promotes the development of IL-17-producing T cells and psoriasiform skin inflammation.
Topics: Animals; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Imidazoles; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Interleukin-6; Langerhans Cells; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 14; Psoriasis; Pyridines; Signal Transduction; Skin; T-Lymphocytes; Th17 Cells | 2018 |
The severity of imiquimod-induced mouse skin inflammation is independent of endogenous IL-38 expression.
Topics: Aminoquinolines; Animals; Cells, Cultured; Dermatitis; Disease Models, Animal; Drug Eruptions; Female; Imiquimod; Inflammation; Interleukin-1; Interleukins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Severity of Illness Index; Skin | 2018 |
The healing power of painful memories.
Topics: Aminoquinolines; Animals; Chromatin; Epidermal Cells; Epidermis; Humans; Imiquimod; Immunologic Memory; Inflammation; Mice; Protein Domains; Regeneration; Stem Cells; Toll-Like Receptor 7 | 2018 |
Maresin-1 suppresses imiquimod-induced skin inflammation by regulating IL-23 receptor expression.
Topics: Animals; CD4-Positive T-Lymphocytes; Docosahexaenoic Acids; Gene Expression Regulation; Imiquimod; Inflammation; Interleukin-17; Intraepithelial Lymphocytes; Mice; Receptors, Interleukin; Skin | 2018 |
Topical heat shock protein 70 prevents imiquimod-induced psoriasis-like inflammation in mice.
Topics: Administration, Cutaneous; Animals; Cytokines; HSP70 Heat-Shock Proteins; Imiquimod; Inflammation; Mice, Inbred BALB C; Psoriasis; Skin Cream | 2018 |
An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation.
Topics: Animals; Cell Line; Cell Proliferation; Enzyme Activation; HEK293 Cells; Humans; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Receptors, Interleukin; Receptors, Interleukin-17; Skin; STAT3 Transcription Factor | 2018 |
The Therapeutic Potential and Molecular Mechanism of Isoflavone Extract against Psoriasis.
Topics: Animals; Antioxidants; Cytokines; Disease Models, Animal; Epidermis; Foreskin; Humans; Imiquimod; Inflammation; Interleukin-17; Interleukin-22; Interleukins; Isoflavones; Keratinocytes; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; Signal Transduction; Skin; Tumor Necrosis Factor-alpha | 2018 |
Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation.
Topics: Animals; Cell Differentiation; Cell Proliferation; Epidermis; Gene Expression Regulation; Glucocorticoids; Imiquimod; Inflammation; Keratinocytes; Mice, Knockout; NF-kappa B; Phenotype; Phosphorylation; Psoriasis; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
Acetyl-11-keto-β-boswellic acid inhibits the secretion of cytokines by dendritic cells via the TLR7/8 pathway in an imiquimod-induced psoriasis mouse model and in vitro.
Topics: Aminoquinolines; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Coculture Techniques; Cytokines; Dendritic Cells; Erythema; Imiquimod; Inflammation; Interleukin-12 Subunit p35; Interleukin-23 Subunit p19; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Psoriasis; RNA, Messenger; Signal Transduction; Spleen; Toll-Like Receptor 7; Toll-Like Receptor 8; Triterpenes | 2018 |
TLR7-let-7 Signaling Contributes to Ethanol-Induced Hepatic Inflammatory Response in Mice and in Alcoholic Hepatitis.
Topics: Adult; Aged; Animals; Central Nervous System Depressants; Cytokines; Ethanol; Female; Hepatitis, Alcoholic; Hepatocytes; Humans; Imiquimod; Inflammation; Interleukin-8; Liver; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; MicroRNAs; Middle Aged; Primary Cell Culture; RNA, Messenger; Toll-Like Receptor 7; Transport Vesicles | 2018 |
Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes.
Topics: Adolescent; Adult; Animals; Apoptosis; Case-Control Studies; Cell Proliferation; Disease Models, Animal; Female; Gene Knockdown Techniques; Humans; Imiquimod; Inflammation; Keratinocytes; Male; Mice, Inbred BALB C; Middle Aged; Psoriasis; Skin; WT1 Proteins; Young Adult | 2018 |
Aldara-induced dermatitis is associated with development of liver fibrosis in mice.
Topics: Aminoquinolines; Animals; Disease Models, Animal; Imiquimod; Inflammation; Liver Cirrhosis; Mice | 2018 |
Dang-Gui-Liu-Huang Tang a traditional herbal formula, ameliorates imiquimod-induced psoriasis-like skin inflammation in mice by inhibiting IL-22 production.
Topics: Administration, Cutaneous; Aminoquinolines; Angelica sinensis; Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Imiquimod; Inflammation; Interleukin-22; Interleukins; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Th17 Cells; Tumor Necrosis Factor-alpha | 2018 |
Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis.
Topics: Animals; Calcitonin Gene-Related Peptide; Denervation; Disease Models, Animal; Diterpenes; Imiquimod; Inflammation; Male; Mice; Mice, Inbred C57BL; Psoriasis; Reactive Nitrogen Species; Reactive Oxygen Species; Sensory Receptor Cells; Skin; Substance P; TRPA1 Cation Channel; TRPV Cation Channels | 2019 |
A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice.
Topics: Animals; Cytokines; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Transgenic; Psoriasis; Skin; Toll-Like Receptor 7 | 2018 |
The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasis.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Mice; NF-kappa B; Organ Culture Techniques; Psoriasis; Signal Transduction; Skin; Tumor Necrosis Factor-alpha; Xanthones | 2018 |
IL-36α is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity.
Topics: Animals; Cell Movement; Dendritic Cells; Dermatitis; Dermatitis, Contact; Haptens; Imiquimod; Inflammation; Interleukin-1; Keratinocytes; Lymph Nodes; Mice, Inbred C57BL; Psoriasis; Skin; T-Lymphocytes | 2018 |
Antagonization of IL-17A Attenuates Skin Inflammation and Vascular Dysfunction in Mouse Models of Psoriasis.
Topics: Animals; Antibodies, Blocking; Aorta; Disease Models, Animal; Disease Progression; Humans; Imiquimod; Immunotherapy; Inflammation; Interleukin-17; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Oxidative Stress; Psoriasis; Reactive Oxygen Species; Skin; Vascular Diseases | 2019 |
Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation.
Topics: Adult; Aged; Aged, 80 and over; Animals; Female; Forkhead Transcription Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imiquimod; Inflammation; Male; Mice, Inbred C57BL; Middle Aged; Neutralization Tests; Phagocytes; Psoriasis; Receptors, Antigen, T-Cell, alpha-beta; Skin; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 2018 |
Downregulated Caveolin-1 expression in circulating monocytes may contribute to the pathogenesis of psoriasis.
Topics: Animals; Caveolin 1; Chemotaxis; Down-Regulation; Humans; Imiquimod; Inflammation; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Mice; Monocytes; Psoriasis | 2019 |
Long-term outcomes of imiquimod-treated lentigo maligna.
Topics: Adjuvants, Immunologic; Administration, Topical; Aged; Aged, 80 and over; Biopsy; Dose-Response Relationship, Drug; Female; Humans; Hutchinson's Melanotic Freckle; Imiquimod; Inflammation; Male; Middle Aged; Pigmentation; Retrospective Studies; Skin Neoplasms; Treatment Outcome | 2019 |
Topical Application of a Dual ABC Transporter Substrate and NF-κB Inhibitor Blocks Multiple Sources of Cutaneous Inflammation in Mouse Skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; NF-kappa B; Nicotinic Acids; Nitriles; Piperidines; Pyrrolidines; Skin; Skin Neoplasms | 2019 |
Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways.
Topics: Animals; Dermatitis, Contact; Disease Models, Animal; Fibroblasts; Gene Expression Regulation; Ghrelin; Humans; Imiquimod; Immune System Diseases; Inflammation; Mice; NF-kappa B; Oxazolone; Psoriasis; RAW 264.7 Cells; Signal Transduction; Skin; Tumor Necrosis Factor-alpha | 2019 |
Inhibiting Sphingosine Kinase 2 Derived-sphingosine-1-phosphate Ameliorates Psoriasis-like Skin Disease via Blocking Th17 Differentiation of Naïve CD4 T Lymphocytes in Mice.
Topics: Administration, Topical; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Ceramidases; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Imiquimod; Immunity; Inflammation; Interleukin-17; Lysophospholipids; Male; Mice; Phosphotransferases (Alcohol Group Acceptor); Psoriasis; Quinolones; RNA, Messenger; Sphingosine; Suppressor of Cytokine Signaling 1 Protein; Th17 Cells | 2019 |
Cholecystokinin Downregulates Psoriatic Inflammation by Its Possible Self-Regulatory Effect on Epidermal Keratinocytes.
Topics: Animals; Autocrine Communication; Cholecystokinin; Down-Regulation; Epidermis; Female; Humans; Imiquimod; Inflammation; Interleukin-17; Interleukin-6; Keratinocytes; Male; Mice; Oligopeptides; Paracrine Communication; Psoriasis; Signal Transduction | 2019 |
Imiquimod-induced skin inflammation is relieved by knockdown of sodium channel Na
Topics: Animals; Dermatitis; Epidermis; Female; Gene Knockdown Techniques; Imiquimod; Inflammation; Psoriasis; Rabbits; RNA Interference; Skin; Voltage-Gated Sodium Channels | 2019 |
IL-33 contributes to disease severity in Psoriasis-like models of mouse.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cytokines; Disease Models, Animal; Female; Humans; Imiquimod; Inflammation; Interleukin-17; Interleukin-33; Interleukins; Mice; Mice, Inbred BALB C; Psoriasis; Skin; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2019 |
Protective effects of ambroxol in psoriasis like skin inflammation: Exploration of possible mechanisms.
Topics: Ambroxol; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Humans; Hyperplasia; Imiquimod; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Psoriasis; RAW 264.7 Cells; Signal Transduction; Skin | 2019 |
IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells.
Topics: Animals; Antibodies; Cell Differentiation; Cytokines; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukin-1; Interleukin-1 Receptor Accessory Protein; Interleukin-17; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Receptors, Antigen, T-Cell, gamma-delta; Regeneration; Skin; T-Lymphocytes | 2019 |
Synthesis and identification of quinoline derivatives as topoisomerase I inhibitors with potent antipsoriasis activity in an animal model.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Ear; Imiquimod; Inflammation; Male; Mice, Inbred BALB C; Psoriasis; Quinolines; Skin; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors | 2019 |
Transient receptor potential ankyrin 1 (TRPA1) positively regulates imiquimod-induced, psoriasiform dermal inflammation in mice.
Topics: Adult; Animals; Dermis; Epidermis; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Keratosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Psoriasis; RNA, Messenger; Th17 Cells; TRPA1 Cation Channel | 2019 |
Imiquimod and interferon-alpha augment monocyte-mediated astrocyte secretion of MCP-1, IL-6 and IP-10 in a human co-culture system.
Topics: Astrocytes; Cell Line; Chemokine CCL2; Chemokine CXCL10; Coculture Techniques; Humans; Imiquimod; Inflammation; Interferon-alpha; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Monocytes; Neuroimmunomodulation; Recombinant Proteins; Toll-Like Receptor 7 | 2019 |
Caspase-11-Mediated Cell Death Contributes to the Pathogenesis of Imiquimod-Induced Psoriasis.
Topics: Animals; Caspases, Initiator; Cell Death; Cell Proliferation; Disease Models, Animal; Humans; Imiquimod; Inflammation; Interleukin-1beta; Mice; Mice, Knockout; Neovascularization, Pathologic; Psoriasis; Ribonuclease, Pancreatic; Skin | 2019 |
Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin inflammation in mice.
Topics: Animals; Astragalus propinquus; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Humans; Imiquimod; Inflammasomes; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Psoriasis; Pyroptosis; Sapogenins; Skin | 2019 |
Mannan-binding lectin promotes keratinocyte to produce CXCL1 and enhances neutrophil infiltration at the early stages of psoriasis.
Topics: Animals; Cell Line, Transformed; Chemokine CXCL1; Chemotaxis, Leukocyte; Dermis; Female; Humans; Imiquimod; Inflammation; Keratinocytes; Mannose-Binding Lectin; Metabolism, Inborn Errors; Mice; Mice, Knockout; Neutrophils; Psoriasis; Specific Pathogen-Free Organisms; Up-Regulation | 2019 |
Long-term outcomes of imiquimod-treated lentigo maligna: add on cryosurgery to induce inflammation and increase efficacy?
Topics: Cryosurgery; Humans; Hutchinson's Melanotic Freckle; Imiquimod; Inflammation; Melanoma; Skin Neoplasms | 2020 |
Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.
Topics: Aminoquinolines; Animals; Antigens, CD19; Antigens, CD1d; B-Lymphocytes, Regulatory; CD4-Positive T-Lymphocytes; CD5 Antigens; Humans; Imiquimod; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-17; Lymph Nodes; Lymphocyte Count; Mice; Mice, Inbred C57BL; Phenotype; Psoriasis; RNA, Messenger; Skin; Spleen | 2013 |
Curcumin inhibits imiquimod-induced psoriasis-like inflammation by inhibiting IL-1beta and IL-6 production in mice.
Topics: Aminoquinolines; Animals; Cell Proliferation; Curcumin; Ear; Gene Expression Regulation; Imiquimod; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Antigen, T-Cell, gamma-delta; Receptors, CCR6; RNA, Messenger; Skin | 2013 |
Neu1 sialidase and matrix metalloproteinase-9 cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 and -9 activation, cellular signaling and pro-inflammatory responses.
Topics: Aminoquinolines; Animals; Cell Line; Endosomes; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Imiquimod; Inflammation; Interferon Inducers; Macrophages; Matrix Metalloproteinase 9; Mice; Neuraminidase; NF-kappa B; Oligonucleotides; Oseltamivir; Receptors, Bombesin; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 9 | 2013 |
Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.
Topics: Aminoquinolines; Butadienes; Cells, Cultured; Complement C5a; Extracellular Signal-Regulated MAP Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Imiquimod; Inflammation; Interleukin-10; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Monocytes; Nitriles; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Poly I-C; Proto-Oncogene Proteins c-raf; Receptor, Anaphylatoxin C5a; Receptors, Complement; Salmonella typhimurium; Toll-Like Receptor 4; Tumor Necrosis Factors | 2013 |
[Expression of NLRP3 inflammasome in BALB/c mice with imiquimod-induced psoriasis-like inflammation and therapeutic effect of mustard seed (Sinapis Alba Linn)].
Topics: Aminoquinolines; Animals; Carrier Proteins; Caspase 1; Female; Imiquimod; Inflammasomes; Inflammation; Interleukin-18; Interleukin-1beta; Mice; Mice, Inbred BALB C; Mustard Plant; NLR Family, Pyrin Domain-Containing 3 Protein; Phytotherapy; Psoriasis; Seeds | 2013 |
Editorial: are regulatory B10 cells a viable target for autoimmune diseases?
Topics: Aminoquinolines; Animals; B-Lymphocytes, Regulatory; Humans; Imiquimod; Inflammation; Psoriasis; Skin | 2013 |
Designing a simple organic salt-based supramolecular topical gel capable of displaying in vivo self-delivery application.
Topics: Administration, Topical; Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Carriers; Drug Design; Gels; Imiquimod; Inflammation; Male; Mice; Naproxen; Peptides; Salts | 2014 |
Endogenous n-3 polyunsaturated fatty acids protect against imiquimod-induced psoriasis-like inflammation via the IL-17/IL-23 axis.
Topics: Aminoquinolines; Animals; Cell Differentiation; Cytokines; Disease Models, Animal; Fatty Acids, Omega-3; Female; Imiquimod; Inflammation; Inflammation Mediators; Interleukin-17; Interleukin-23; Keratinocytes; Male; Mice; Mice, Transgenic; Organ Size; Protective Agents; Psoriasis; Spleen; Th17 Cells | 2014 |
Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.
Topics: Aminoquinolines; Animals; Disease Models, Animal; Female; Imiquimod; Inflammation; Interleukin-17; Interleukin-22; Interleukin-23; Interleukins; Langerhans Cells; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; NAV1.8 Voltage-Gated Sodium Channel; Nociceptors; Psoriasis; Sensory Receptor Cells; Skin; T-Lymphocytes; TRPV Cation Channels | 2014 |
TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Cytokines; Imiquimod; Inflammation; Kruppel-Like Transcription Factors; Mice; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Promyelocytic Leukemia Zinc Finger Protein; Psoriasis; Th17 Cells; Toll-Like Receptor 4 | 2014 |
Skin-penetrating methotrexate alleviates imiquimod-induced psoriasiform dermatitis via decreasing IL-17-producing gamma delta T cells.
Topics: Aminoquinolines; Animals; CD11c Antigen; CD4-Positive T-Lymphocytes; Cytokines; Dermatitis; DNA, Complementary; Female; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Methotrexate; Mice; Mice, Inbred BALB C; Peptides; Permeability; Psoriasis; Skin | 2014 |
Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Aryl Hydrocarbon Hydroxylases; Azo Compounds; Basic Helix-Loop-Helix Transcription Factors; Carbazoles; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytokines; Environmental Exposure; Humans; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Knockout; Psoriasis; Pyrazoles; Receptors, Aryl Hydrocarbon; Signal Transduction; Skin; Transcription Factors; Up-Regulation | 2014 |
Recruitment of plasmacytoid dendritic cells to skin regulates treatment responsiveness of actinic keratosis to imiquimod.
Topics: Adjuvants, Immunologic; Aminoquinolines; Biopsy; Cytokines; Dendritic Cells; Humans; Imiquimod; Inflammation; Interferon-alpha; Keratosis, Actinic; RNA, Messenger; Skin; Toll-Like Receptor 7; Wound Healing | 2014 |
Nanomiemgel--a novel drug delivery system for topical application--in vitro and in vivo evaluation.
Topics: Administration, Cutaneous; Aminoquinolines; Animals; Capsaicin; Cell Proliferation; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Drug Stability; Emulsions; Gels; Humans; Imiquimod; Immunohistochemistry; In Vitro Techniques; Inflammation; Keratinocytes; Micelles; Microdialysis; Microscopy, Atomic Force; Nanoparticles; Organ Size; Permeability; Psoriasis; Rats; Rheology; Skin Absorption; Spleen | 2014 |
Deficiency of both L-selectin and ICAM-1 exacerbates imiquimod-induced psoriasis-like skin inflammation through increased infiltration of antigen presenting cells.
Topics: Aminoquinolines; Animals; Antigen-Presenting Cells; Cell Movement; Imiquimod; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-17; L-Selectin; Mice; Mice, Knockout; Psoriasis; Real-Time Polymerase Chain Reaction; Severity of Illness Index; Skin | 2015 |
Anti-WASP intrabodies inhibit inflammatory responses induced by Toll-like receptors 3, 7, and 9, in macrophages.
Topics: Aminoquinolines; Animals; Antibodies; Bone Marrow Cells; Cytokines; Imiquimod; Inflammation; Macrophages; Membrane Glycoproteins; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Phosphorylation; Poly I-C; Single-Chain Antibodies; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 9; Wiskott-Aldrich Syndrome Protein | 2015 |
Glycyrrhizin ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice and inhibits TNF-α-induced ICAM-1 expression via NF-κB/MAPK in HaCaT cells.
Topics: Aminoquinolines; Animals; Cell Adhesion; Cell Line; Cell Survival; Female; Glycyrrhizic Acid; Humans; Imiquimod; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Phosphorylation; Psoriasis; Signal Transduction; Skin Diseases; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Dual Inhibition of TNFR1 and IFNAR1 in Imiquimod-Induced Psoriasiform Skin Inflammation in Mice.
Topics: Aminoquinolines; Animals; Antibodies, Monoclonal; Calgranulin A; Etanercept; Imiquimod; Immunoglobulin G; Inflammation; Infliximab; Interferon Type I; Interleukin-12 Subunit p40; Interleukin-17; Interleukin-23 Subunit p19; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Psoriasis; Receptor, Interferon alpha-beta; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Skin; Tumor Necrosis Factor-alpha | 2015 |
Probing the effects of fish oil on the delivery and inflammation-inducing potential of imiquimod.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents; Delayed-Action Preparations; Female; Fish Oils; Imiquimod; Inflammation; Mice; Permeability; Psoriasis; Skin; Skin Absorption | 2015 |
Inflammation induces dermal Vγ4+ γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17-driven responses.
Topics: Aminoquinolines; Animals; Imiquimod; Immunologic Memory; Inflammation; Interleukin-17; Mice; Receptors, Antigen, T-Cell, gamma-delta; Skin; T-Lymphocytes | 2015 |
Imiquimod-induced psoriasis-like skin inflammation is suppressed by BET bromodomain inhibitor in mice through RORC/IL-17A pathway modulation.
Topics: Aminoquinolines; Animals; Azepines; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-17; Interleukin-22; Interleukins; Male; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Signal Transduction; Skin; Triazoles | 2015 |
The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes.
Topics: Aminoquinolines; Gene Expression Regulation, Viral; Humans; Imiquimod; Immunity, Innate; Inflammation; Keratinocytes; NF-kappa B; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Papillomavirus Infections; Primary Cell Culture; Repressor Proteins; Toll-Like Receptor 7 | 2015 |
Selective CD28 antagonist prevents Aldara-induced skin inflammation in non-human primates.
Topics: Administration, Topical; Aminoquinolines; Animals; B7-1 Antigen; B7-2 Antigen; B7-H1 Antigen; CD28 Antigens; CTLA-4 Antigen; Imiquimod; Inflammation; Lymphocyte Activation; Papio; Skin; T-Lymphocytes | 2016 |
Percutaneous delivery of α-melanocyte-stimulating hormone for the treatment of imiquimod-induced psoriasis.
Topics: Administration, Cutaneous; alpha-MSH; Aminoquinolines; Animals; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Ethylene Glycols; Gels; Imiquimod; Inflammation; Male; Mice; Mice, Inbred C57BL; Microdialysis; Psoriasis; Rats; Rats, Sprague-Dawley; Skin Absorption | 2016 |
Distinct expression of interleukin (IL)-36α, β and γ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease.
Topics: Aminoquinolines; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Caco-2 Cells; Cell Line; Crohn Disease; Dendritic Cells; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Imiquimod; Inflammation; Interleukin-1; Interleukins; Intestinal Mucosa; Keratinocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Plasma Cells; Psoriasis; RNA, Messenger; Skin; Synovial Membrane; Th17 Cells | 2016 |
Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; B7-H1 Antigen; Humans; Imiquimod; Inflammation; Interleukin-17; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor; Psoriasis; Recombinant Proteins; Skin; T-Lymphocyte Subsets | 2016 |
Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies.
Topics: Aminoquinolines; Animals; Arthritis, Experimental; Cells, Cultured; Collagen; Dermatitis; Encephalomyelitis, Autoimmune, Experimental; Imiquimod; Inflammation; Mice; Mice, Transgenic; Mutation; RNA, Messenger; Tristetraprolin | 2016 |
Comment on 'Tumour necrosis factor-α plays a significant role in the Aldara-induced skin inflammation in mice'.
Topics: Aminoquinolines; Animals; Imiquimod; Inflammation; Mice; Psoriasis; Tumor Necrosis Factor-alpha | 2016 |
Inhibitory Effect of Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice by Histamine H4 Receptor Agonist 4-Methylhistamine.
Topics: Aminoquinolines; Animals; Cell Movement; Cytokines; Disease Models, Animal; Female; Forkhead Transcription Factors; Humans; Imiquimod; Inflammation; Interleukin-2 Receptor alpha Subunit; Methylhistamines; Mice; Mice, Inbred C57BL; Psoriasis; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Skin; T-Lymphocytes, Regulatory; Th1 Cells | 2016 |
Increased Lipocalin-2 Contributes to the Pathogenesis of Psoriasis by Modulating Neutrophil Chemotaxis and Cytokine Secretion.
Topics: Adolescent; Adult; Aminoquinolines; Animals; Antibodies, Monoclonal; Biopsy; Cell Differentiation; Chemotaxis; Cytokines; Epidermis; Female; HL-60 Cells; Humans; Imiquimod; Inflammation; Lipocalin-2; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Middle Aged; Neutrophils; Psoriasis; Recombinant Proteins; RNA, Small Interfering; Young Adult | 2016 |
Comment on 'Tumour necrosis factor-α plays a significant role in the Aldara-induced skin inflammation in mice': reply from authors.
Topics: Aminoquinolines; Animals; Imiquimod; Inflammation; Mice; Psoriasis; Tumor Necrosis Factor-alpha | 2016 |
MCPIP1 RNase Is Aberrantly Distributed in Psoriatic Epidermis and Rapidly Induced by IL-17A.
Topics: Aminoquinolines; Animals; Antigens, Differentiation, T-Lymphocyte; Biopsy; Coculture Techniques; Epidermis; Gene Silencing; Humans; Imiquimod; Inflammation; Interleukin-17; Keratinocytes; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Phosphorylation; Psoriasis; Receptors, Interleukin-17; Ribonucleases; Skin; STAT3 Transcription Factor; Transcription Factors; Tumor Necrosis Factor-alpha | 2016 |
Multi-glycoside of Tripterygium wilfordii Hook. f. ameliorates imiquimod-induced skin lesions through a STAT3-dependent mechanism involving the inhibition of Th17-mediated inflammatory responses.
Topics: Aminoquinolines; Animals; CD4-Positive T-Lymphocytes; Cytokines; Gene Expression; Glycosides; Imiquimod; Immunohistochemistry; Inflammation; Inflammation Mediators; Interleukin-17; Mice, Inbred BALB C; Phosphorylation; Phytotherapy; Protective Agents; Psoriasis; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Diseases; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells; Tripterygium | 2016 |
Luteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model.
Topics: Acanthosis Nigricans; Aminoquinolines; Animals; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Glucosides; Humans; Imiquimod; Immunohistochemistry; Inflammation; Interleukin-22; Interleukins; Keratinocytes; Lipids; Luteolin; Mice, Inbred C57BL; Oxidation-Reduction; Phenotype; Protein Transport; Psoriasis; Signal Transduction; STAT3 Transcription Factor | 2016 |
Spread of Psoriasiform Inflammation to Remote Tissues Is Restricted by the Atypical Chemokine Receptor ACKR2.
Topics: Aminoquinolines; Animals; Biopsy, Needle; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Imiquimod; Immunohistochemistry; Inflammation; Keratinocytes; Mice; Mice, Inbred C57BL; Phenotype; Polymerase Chain Reaction; Psoriasis; Random Allocation; Receptors, Chemokine; Reference Values; Statistics, Nonparametric; Up-Regulation | 2017 |
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
Topics: Aminoquinolines; Animals; Antioxidants; Body Weight; Catechin; Cytokines; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Spleen | 2016 |
Novel Fish Oil-based Bigel System for Controlled Drug Delivery and its Influence on Immunomodulatory Activity of Imiquimod Against Skin Cancer.
Topics: Aminoquinolines; Animals; Cell Line; Delayed-Action Preparations; Drug Delivery Systems; Female; Fish Oils; Humans; Hydrogels; Imiquimod; Immunologic Factors; Inflammation; Interleukin-10; Interleukin-6; Mice; Skin; Skin Neoplasms; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2017 |
Effects of Depilation Methods on Imiquimod-Induced Skin Inflammation in Mice.
Topics: Aminoquinolines; Animals; Disease Models, Animal; Hair Removal; Imiquimod; Inflammation; Injections, Subcutaneous; Interleukin-23; Mice; Mice, Inbred C57BL; Random Allocation; Reference Values; Treatment Outcome | 2017 |
IL-12 protects from psoriasiform skin inflammation.
Topics: Aminoquinolines; Animals; Female; Humans; Imiquimod; Inflammation; Interleukin-12; Interleukin-23; Keratinocytes; Mice, Inbred C57BL; Psoriasis; Receptors, Antigen, T-Cell, gamma-delta; Skin | 2016 |
The Snowballing Literature on Imiquimod-Induced Skin Inflammation in Mice: A Critical Appraisal.
Topics: Aminoquinolines; Animals; Dermatitis; Dermatology; Disease Models, Animal; Humans; Imiquimod; Inflammation; Mice; Psoriasis; Research Design | 2017 |
Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Dendritic Cells; Drug Eruptions; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Interleukin-23; Langerhans Cells; Major Histocompatibility Complex; Membrane Proteins; Mice; Mice, Knockout; Monocytes; Psoriasis; Skin | 2016 |
Imiquimod Treatment Causes Systemic Disease in Mice Resembling Generalized Pustular Psoriasis in an IL-1 and IL-36 Dependent Manner.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Body Temperature; Disease Models, Animal; Female; Imiquimod; Inflammation; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Pain Measurement; Psoriasis; Receptors, Interleukin-1 Type I; Sex Factors; Skin | 2016 |
Tonsil-derived mesenchymal stem cells (T-MSCs) prevent Th17-mediated autoimmune response via regulation of the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway.
Topics: Animals; Autoimmunity; B7-H1 Antigen; Cell Differentiation; Culture Media, Conditioned; Female; Gene Expression Regulation; Imiquimod; Inflammation; Interleukin-17; Lymph Nodes; Mesenchymal Stem Cells; Mice, Inbred C57BL; Palatine Tonsil; Psoriasis; Side-Population Cells; Signal Transduction; Skin; Th17 Cells | 2018 |
GPR43 activation enhances psoriasis-like inflammation through epidermal upregulation of IL-6 and dual oxidase 2 signaling in a murine model.
Topics: Acetamides; Acetates; Aminoquinolines; Animals; Disease Models, Animal; Dual Oxidases; Epidermis; Imiquimod; Inflammation; Interleukin-6; Male; Mice, Inbred BALB C; Models, Biological; Psoriasis; Receptors, G-Protein-Coupled; Signal Transduction; Th17 Cells; Up-Regulation | 2017 |
Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase.
Topics: Acetylcysteine; Aminoquinolines; Animals; Antioxidants; Buthionine Sulfoximine; Disease Models, Animal; Humans; Imiquimod; Inflammation; Kidney; Kidney Diseases; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Psoriasis | 2017 |
Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma.
Topics: Adaptation, Physiological; Adjuvants, Immunologic; Aminoquinolines; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chronic Disease; Cytokines; Female; Gene Expression Regulation; Hydroxyproline; Imiquimod; Immunoglobulin E; Inflammation; Lung; Mice; Mice, Inbred BALB C; Transforming Growth Factor beta1 | 2009 |
5'-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages.
Topics: Aminoquinolines; Animals; Cell Line, Tumor; Dendritic Cells; Deoxyribonuclease I; Drug Synergism; Endocytosis; Endodeoxyribonucleases; Foot; Imiquimod; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Nucleotides; Oligodeoxyribonucleotides; Organophosphates; Plasmids; Poly I-C; Spleen; Toll-Like Receptor 9; Tumor Necrosis Factor-alpha | 2011 |
Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs.
Topics: Administration, Cutaneous; Aminoquinolines; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drug Delivery Systems; Humans; Hypromellose Derivatives; Imiquimod; Immunohistochemistry; Inflammation; Methylcellulose; Mice; Mice, Inbred C57BL; Nanogels; Nanoparticles; Particle Size; Permeability; Polyethylene Glycols; Polyethyleneimine; Psoriasis; Rheology; Skin; Surface Properties; Viscosity | 2012 |
Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents; Autophagy; Blotting, Western; Cytokines; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Imiquimod; Immunohistochemistry; Inflammation; Inflammation Mediators; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; NF-kappa B; Plaque, Atherosclerotic; Rabbits; Time Factors; Toll-Like Receptor 7; U937 Cells | 2012 |
Clearance of invasive melanoma with topical imiquimod.
Topics: Administration, Topical; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Biopsy; Female; Frail Elderly; Humans; Imiquimod; Inflammation; Melanoma; Neoplasm Invasiveness; Skin; Skin Neoplasms | 2013 |
Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod.
Topics: Aminoquinolines; Animals; Antineoplastic Agents; Cell Movement; Dendritic Cells; Flow Cytometry; Imiquimod; Inflammation; Melanoma; Mice; Skin; Spleen | 2004 |
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
Topics: Adaptor Proteins, Signal Transducing; Aminoquinolines; Animals; Antiviral Agents; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cells, Cultured; Cytoskeletal Proteins; Enzyme Activation; Female; Imidazoles; Imiquimod; Inflammation; Interleukin-1; Interleukin-18; Legionella pneumophila; Listeria monocytogenes; Macrophages, Peritoneal; Male; Mice; Mitogen-Activated Protein Kinases; Multiprotein Complexes; Myeloid Differentiation Factor 88; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; RNA, Bacterial; Toll-Like Receptors | 2006 |
Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells.
Topics: Amino Acid Substitution; Aminoquinolines; Carrier Proteins; Cathepsin B; Cell Death; Cell Line; Dipeptides; Humans; Imiquimod; Inflammation; Lysosomes; Mitochondria; Models, Biological; Monocytes; Mutagenesis, Site-Directed; Mutation; Necrosis; NLR Family, Pyrin Domain-Containing 3 Protein; Recombinant Proteins; Transfection | 2007 |
Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice.
Topics: Adjuvants, Immunologic; Agranulocytosis; Aminoquinolines; Animals; Antigens; Cell Movement; Imiquimod; Immunity, Cellular; Immunity, Innate; Immunization; Immunoglobulin E; Inflammation; Interleukin-1beta; Langerhans Cells; Ligands; Mast Cells; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Skin; T-Lymphocytes, Cytotoxic; Toll-Like Receptor 7; Tumor Necrosis Factor-alpha; Vaccines | 2007 |
Nature of inflammatory infiltrate in superficial cutaneous malignancies during topical imiquimod treatment.
Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; Aminoquinolines; Biomarkers, Tumor; Bowen's Disease; Carcinoma in Situ; Carcinoma, Basal Cell; Female; Humans; Hutchinson's Melanotic Freckle; Imiquimod; Inflammation; Keratosis; Male; Melanoma; Middle Aged; Skin Neoplasms | 2007 |
FAK-mediated activation of ERK for eosinophil migration: a novel mechanism for infection-induced allergic inflammation.
Topics: Adjuvants, Immunologic; Aminoquinolines; Cell Adhesion Molecules; Cell Movement; Cell Survival; Eosinophils; Extracellular Signal-Regulated MAP Kinases; Flagellin; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Peptidoglycan; Phosphorylation; Signal Transduction; Toll-Like Receptors | 2008 |
EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma.
Topics: Aminoquinolines; Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspases; Cell Division; Cytochromes c; G2 Phase; Human T-lymphotropic virus 1; Humans; Imiquimod; Inflammation; Inhibitor of Apoptosis Proteins; Jurkat Cells; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Activation; Lymphoma, T-Cell; Membrane Potential, Mitochondrial; NF-kappa B; Quinoxalines; Skin Neoplasms; Tumor Suppressor Protein p53 | 2008 |
Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Animals, Newborn; Astrocytes; Brain; Cell Line; Central Nervous System; Cytokines; Guanosine; Imidazoles; Imiquimod; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Quinolines; Toll-Like Receptor 7; Toll-Like Receptor 8 | 2008 |
Attenuation of virus-induced airway dysfunction in rats treated with imiquimod.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Imiquimod; Inflammation; Interferons; Male; Rats; Respiratory Tract Diseases; Respirovirus; Respirovirus Infections | 1998 |