imipramine has been researched along with Xerostomia in 27 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Saffron at this dose was found to be effective similar to imipramine in the treatment of mild to moderate depression (F = 2." | 9.11 | Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. ( Afkham, K; Akhondzadeh, S; Fallah-Pour, H; Jamshidi, AH; Khalighi-Cigaroudi, F, 2004) |
| "An international, multicenter, placebo-controlled study was undertaken to determine the safety and antidepressant efficacy of moclobemide, a new reversible inhibitor of monoamine oxidase A, and imipramine in the treatment of dysthymia (DSM-III-R)." | 9.08 | Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group. ( Amrein, R; Stabl, M; Versiani, M, 1997) |
| "Patients treated with imipramine plus CBT experienced less severe fatigue/weakness, dry mouth, and sweating and had a lower rate of dropout due to side effects compared with those treated with imipramine only." | 5.12 | A comparison of medication side effect reports by panic disorder patients with and without concomitant cognitive behavior therapy. ( Barlow, D; Goetz, R; Gorman, J; Gorman, L; Lewin, D; Marcus, SM; Martinez, J; Mosovich, S; Ray, S; Shear, MK; Woods, S, 2007) |
| "Saffron at this dose was found to be effective similar to imipramine in the treatment of mild to moderate depression (F = 2." | 5.11 | Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. ( Afkham, K; Akhondzadeh, S; Fallah-Pour, H; Jamshidi, AH; Khalighi-Cigaroudi, F, 2004) |
| "An international, multicenter, placebo-controlled study was undertaken to determine the safety and antidepressant efficacy of moclobemide, a new reversible inhibitor of monoamine oxidase A, and imipramine in the treatment of dysthymia (DSM-III-R)." | 5.08 | Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group. ( Amrein, R; Stabl, M; Versiani, M, 1997) |
| "An analysis was made of the occurrence of anticholinergic side effects in 15 multicenter studies of 379 patients with endogenous depression who received either trazodone, imipramine, or placebo." | 3.66 | Lack of anticholinergic side effects with a new antidepressent--trazodone. ( Gershon, S; Newton, R, 1980) |
| " Therapy was initiated at 50 mg/day; thereafter, dosage ranged between 100 and 300 mg/day for both drugs." | 2.66 | A double-blind placebo-controlled study of fluvoxamine and imipramine in depression. ( Dominguez, RA; Goldstein, BJ; Jacobson, AF; Steinbook, RM, 1985) |
| "Nomifensine was at least as effective as imipramine in reducing depressive symptoms at average doses of 150 mg/day." | 2.65 | Multicenter double-blind comparison of nomifensine and imipramine for efficacy and safety in depressed outpatients. ( Abrahams, LM; Bremner, JD; Crupie, JE; McCawley, A; Proctor, RC; Sathananthan, GL, 1984) |
| " The findings suggest a more favorable side effect profile for nomifensine, which was associated with a lower frequency of sedating and anticholinergic effects than was seen in the imipramine group." | 2.65 | A double-blind comparative evaluation of the efficacy and safety of nomifensine, imipramine, and placebo in depressed geriatric outpatients. ( Feighner, JP; Hendrickson, G; Merideth, CH, 1984) |
| " Side effect information was collected at each visit." | 2.65 | An overview of side effects and long-term experience with nomifensine from United States clinical trials. ( Hardiman, S; Nash, RJ; Yakabow, AL, 1984) |
| "Dental Caries are an uncommon, but significant side effect of the tricyclic antidepressants and other anticholinergic psychoactive drugs." | 1.26 | Rampant dental caries in the treatment of depression. ( Bassuk, E; Schoonover, S, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (81.48) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akhondzadeh, S | 1 |
| Fallah-Pour, H | 1 |
| Afkham, K | 1 |
| Jamshidi, AH | 1 |
| Khalighi-Cigaroudi, F | 1 |
| Kopittke, L | 1 |
| Gomez, R | 1 |
| Barros, HM | 1 |
| Marcus, SM | 1 |
| Gorman, J | 1 |
| Shear, MK | 1 |
| Lewin, D | 1 |
| Martinez, J | 1 |
| Ray, S | 1 |
| Goetz, R | 1 |
| Mosovich, S | 1 |
| Gorman, L | 1 |
| Barlow, D | 1 |
| Woods, S | 1 |
| Winer, JA | 1 |
| Bahn, S | 1 |
| Bremner, JD | 2 |
| Abrahams, LM | 1 |
| Crupie, JE | 1 |
| McCawley, A | 1 |
| Proctor, RC | 1 |
| Sathananthan, GL | 1 |
| Fann, WE | 1 |
| Lyle, FA | 1 |
| Higginbotham, W | 1 |
| Cohn, JB | 2 |
| Varga, L | 1 |
| Lyford, A | 1 |
| Merideth, CH | 1 |
| Feighner, JP | 1 |
| Hendrickson, G | 1 |
| Yakabow, AL | 1 |
| Hardiman, S | 1 |
| Nash, RJ | 1 |
| von Knorring, L | 1 |
| Garvey, MJ | 2 |
| Tuason, VB | 1 |
| Johnson, RA | 1 |
| Valentine, RH | 1 |
| Cooper, TB | 1 |
| Guy, W | 1 |
| Ban, TA | 1 |
| McEvoy, JP | 1 |
| Petrie, WM | 1 |
| Wilson, WH | 1 |
| Schaffer, JD | 1 |
| Gershon, S | 1 |
| Newton, R | 1 |
| Berzewski, H | 1 |
| Van Moffaert, M | 1 |
| Gagiano, CA | 1 |
| Versiani, M | 1 |
| Amrein, R | 1 |
| Stabl, M | 1 |
| Angst, J | 1 |
| Woggon, B | 1 |
| Schoepf, J | 1 |
| Bassuk, E | 1 |
| Schoonover, S | 1 |
| Bein, HJ | 1 |
| Noyes, R | 1 |
| Cook, BL | 1 |
| Samuelson, L | 1 |
| Wilcox, C | 1 |
| Dominguez, RA | 1 |
| Goldstein, BJ | 1 |
| Jacobson, AF | 1 |
| Steinbook, RM | 1 |
| El-Nabbout, S | 1 |
| Watt, DC | 1 |
| Crammer, JL | 1 |
| Elkes, A | 1 |
| Mindham, RH | 1 |
| Howland, C | 1 |
| Shepherd, M | 1 |
| Rapp, W | 1 |
| Norén, MB | 1 |
| Pedersen, F | 1 |
| Tölle, R | 1 |
18 trials available for imipramine and Xerostomia
| Article | Year |
|---|---|
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816].
Topics: Adult; Crocus; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Phytotherapy; Pilo | 2004 |
A comparison of medication side effect reports by panic disorder patients with and without concomitant cognitive behavior therapy.
Topics: Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Combined Modality Therapy; Fatigue; | 2007 |
Multicenter double-blind comparison of nomifensine and imipramine for efficacy and safety in depressed outpatients.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Double-Blin | 1984 |
Nomifensine vs. imipramine in depressed inpatients.
Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; | 1984 |
A two-center double-blind study of nomifensine, imipramine, and placebo in depressed geriatric outpatients.
Topics: Aged; Akathisia, Drug-Induced; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Doubl | 1984 |
A double-blind comparative evaluation of the efficacy and safety of nomifensine, imipramine, and placebo in depressed geriatric outpatients.
Topics: Aged; Akathisia, Drug-Induced; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Doubl | 1984 |
An overview of side effects and long-term experience with nomifensine from United States clinical trials.
Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Depressive Disorder; Dizziness; Headache; | 1984 |
Fluoxetine in depressed patients: a comparison with imipramine.
Topics: Adult; Aged; Ambulatory Care; Body Weight; Clinical Trials as Topic; Depressive Disorder; Double-Bli | 1984 |
Changes in saliva secretion and accommodation width during short-term administration of imipramine and zimelidine in healthy volunteers.
Topics: Accommodation, Ocular; Adult; Antidepressive Agents; Brompheniramine; Female; Humans; Imipramine; Ma | 1981 |
A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.
Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dizziness; Doxepin; | 1982 |
Efficacy and tolerability of reboxetine compared with imipramine in a double-blind study in patients suffering from major depressive offsodes.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Blood Pressure; Depressive Disorder; Dou | 1997 |
Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Consti | 1997 |
The treatment of depression with L-5-hydroxytryptophan versus imipramine. Results of two open and one double-blind study.
Topics: 5-Hydroxytryptophan; Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergis | 1977 |
A comparison of fluoxetine, imipramine, and placebo in patients with major depressive disorder.
Topics: Adult; Ambulatory Care; Anxiety; Body Weight; Clinical Trials as Topic; Depressive Disorder; Dizzine | 1985 |
A double-blind placebo-controlled study of fluvoxamine and imipramine in depression.
Topics: Adult; Aged; Ambulatory Care; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; | 1985 |
Metabolism, anticholinergic effects, and therapeutic outcome of desmethylimipramine in depressive illness.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Depression; Desipramine; Dose-Response Relations | 1972 |
An evaluation of continuation therapy with tricyclic antidepressants in depressive illness.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Femal | 1973 |
Comparative trial of imipramine N-oxide and imipramine in the treatment of out-patients with depressive syndromes.
Topics: Adult; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Female; Humans; Imipramine | 1973 |
9 other studies available for imipramine and Xerostomia
| Article | Year |
|---|---|
Opposite effects of antidepressants on unstimulated and stimulated salivary flow.
Topics: Amylases; Animals; Antidepressive Agents; Calcium; Fluoxetine; Imipramine; Male; Moclobemide; Muscar | 2005 |
Loss of teeth with antidepressant drug therapy.
Topics: Dental Caries; Diphenhydramine; Humans; Imipramine; Male; Middle Aged; Parkinson Disease; Psychophar | 1967 |
Elevated plasma tricyclic levels with therapeutic doses of imipramine.
Topics: Adult; Depressive Disorder; Desipramine; Electrocardiography; Female; Humans; Hydroxylation; Imipram | 1984 |
Lack of anticholinergic side effects with a new antidepressent--trazodone.
Topics: Adult; Aged; Constipation; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle | 1980 |
Rampant dental caries in the treatment of depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Dental Caries; Depression; Drug Combinations | 1978 |
Prejudices in pharmacology and pharmacotherapy. The so-called anticholinergic effect of antidepressants.
Topics: Heart Rate; Humans; Imipramine; Parasympatholytics; Sympathomimetics; Urination; Xerostomia | 1977 |
Problems with tricyclic antidepressant use in patients with panic disorder or agoraphobia: results of a naturalistic follow-up study.
Topics: Adult; Agoraphobia; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Anxiety Disorders; Ap | 1989 |
[Buccal pH and salivary pathology. Work at the Clinic of Stomatology and Maxillo-facial Surgery. University of Paris].
Topics: Adolescent; Adult; Aged; Butyrophenones; Candidiasis; Chemical Phenomena; Chemistry; Colorimetry; El | 1974 |
[Autonomic effects of thymoleptics and their relationships to the antidepressive effect during the course of therapy].
Topics: Adult; Anthropometry; Antidepressive Agents; Autonomic Nervous System; Blood Circulation; Depression | 1970 |