imipramine has been researched along with Tuberculosis in 3 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Tuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe inhibition of Mycobacterium tuberculosis topoisomerase I (MttopoI), an essential mycobacterial enzyme, by two related compounds, imipramine and norclomipramine, of which imipramine is clinically used as an antidepressant." | 3.81 | Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors. ( Ahmed, W; Bhat, RS; Bradley, EK; Ekins, S; Godbole, AA; Nagaraja, V, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Godbole, AA | 1 |
| Ahmed, W | 1 |
| Bhat, RS | 1 |
| Bradley, EK | 1 |
| Ekins, S | 1 |
| Nagaraja, V | 1 |
| LEVENDEL, L | 1 |
| LAKATOS, M | 1 |
| VARADY, T | 1 |
| Piéron, R | 1 |
| Marien, C | 1 |
| Jagueux, M | 1 |
3 other studies available for imipramine and Tuberculosis
| Article | Year |
|---|---|
Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors.
Topics: Amino Acid Motifs; Bacterial Proteins; Binding Sites; DNA; DNA Topoisomerases, Type I; DNA, Bacteria | 2015 |
[The use of new tranquilizers (Frenolon, Melipramin, Hirepin) in the therapy of tuberculosis, with special reference to the alcoholic tuberculosis patients].
Topics: Chlorpropamide; Imipramine; Promethazine; Reserpine; Tranquilizing Agents; Tuberculosis; Tuberculosi | 1962 |
[Jaundice and rifampicin].
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Imipramine; Isoniazid; Jaundice; Liver | 1971 |