imipramine has been researched along with Tourette Syndrome in 10 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| "[3H]Imipramine binding to blood platelets was assessed in eight untreated Tourette syndrome (TS) children, nine drug-free TS children with obsessive-compulsive disorder (OCD), and nine age-matched and gender-matched control subjects." | 7.68 | Decreased platelet imipramine binding in Tourette syndrome children with obsessive-compulsive disorder. ( Barber, Y; Cohen, A; Mandel, A; Mester, R; Rehavi, M; Weitz, R; Weizman, A, 1992) |
| "A ten year old boy developed features of Tourette syndrome while taking haloperidol for behaviour problems." | 7.68 | A case of Tourette syndrome developing during haloperidol treatment. ( Karagianis, JL; Nagpurkar, R, 1990) |
| "[3H]Imipramine binding to blood platelets was assessed in eight untreated Tourette syndrome (TS) children, nine drug-free TS children with obsessive-compulsive disorder (OCD), and nine age-matched and gender-matched control subjects." | 3.68 | Decreased platelet imipramine binding in Tourette syndrome children with obsessive-compulsive disorder. ( Barber, Y; Cohen, A; Mandel, A; Mester, R; Rehavi, M; Weitz, R; Weizman, A, 1992) |
| "A ten year old boy developed features of Tourette syndrome while taking haloperidol for behaviour problems." | 3.68 | A case of Tourette syndrome developing during haloperidol treatment. ( Karagianis, JL; Nagpurkar, R, 1990) |
| "Gilles de la Tourette's syndrome (GTS) is a chronic neuropsychiatric disorder characterized by multiple involuntary motor and phonic tics associated with behavioural disturbances including obsessive-compulsive and aggressive behavior, depression and, rarely, psychosis." | 1.27 | Beneficial effects of imipramine on Tourette's syndrome. ( Bamford, CR; Sandyk, R, 1988) |
| "A case is reported of a boy with Tourette's syndrome whose panic attacks were successfully treated with imipramine." | 1.27 | Imipramine treatment of panic disorder in a boy with Tourette's syndrome. ( Sverd, J, 1988) |
| "The authors treated two children with Gilles de la Tourette's disease and one child with a probable combination of Gilles de la Tourette's disease and minimal brain dysfunction with methylphenidate, which resulted in exacerbation of symptoms." | 1.26 | The use of methylphenidate and imipramine in Gilles de la Tourette's disease in children. ( Fras, I; Karlavage, J, 1977) |
| "This longitudinal, blind study of Gilles de la Tourette's disease in a 44 year old male patient who was nonresponsive to Haloperidol therapy indicates that dopamine excretion is related to clinical response." | 1.26 | A study of endogenous dopamine metabolism in Gilles de la Tourette's disease. ( Knopp, W; Messiha, FS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ELLISON, RM | 1 |
| Wiener, JM | 1 |
| Fras, I | 2 |
| Karlavage, J | 1 |
| Messiha, FS | 1 |
| Knopp, W | 1 |
| Weizman, A | 1 |
| Mandel, A | 1 |
| Barber, Y | 1 |
| Weitz, R | 1 |
| Cohen, A | 1 |
| Mester, R | 1 |
| Rehavi, M | 1 |
| Karagianis, JL | 1 |
| Nagpurkar, R | 1 |
| Dillon, DC | 1 |
| Salzman, IJ | 1 |
| Schulsinger, DA | 1 |
| Sandyk, R | 1 |
| Bamford, CR | 1 |
| Sverd, J | 1 |
1 review available for imipramine and Tourette Syndrome
| Article | Year |
|---|---|
Psychopharmacology in childhood disorders.
Topics: Anorexia Nervosa; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention Defici | 1984 |
9 other studies available for imipramine and Tourette Syndrome
| Article | Year |
|---|---|
GILLES DE LA TOURETTE'S SYNDROME.
Topics: Chlorpromazine; Chorea; Geriatrics; Humans; Imipramine; Intelligence Tests; Neurotic Disorders; Obse | 1964 |
The use of methylphenidate and imipramine in Gilles de la Tourette's disease in children.
Topics: Acute Disease; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Humans; Imipram | 1977 |
Gilles de la Tourette's syndrome. Effects of tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Haloperidol; Humans; Imipramine; Male; Toure | 1978 |
A study of endogenous dopamine metabolism in Gilles de la Tourette's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Epinephrine; Haloperidol; Homovanillic Acid; Humans | 1976 |
Decreased platelet imipramine binding in Tourette syndrome children with obsessive-compulsive disorder.
Topics: Adolescent; Blood Platelets; Carrier Proteins; Child; Female; Humans; Imipramine; Male; Obsessive-Co | 1992 |
A case of Tourette syndrome developing during haloperidol treatment.
Topics: Aggression; Child; Child Behavior Disorders; Dose-Response Relationship, Drug; Drug Therapy, Combina | 1990 |
The use of imipramine in Tourette's syndrome and attention deficit disorder: case report.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe | 1985 |
Beneficial effects of imipramine on Tourette's syndrome.
Topics: Child; Clonidine; Female; Haloperidol; Humans; Imipramine; Tourette Syndrome | 1988 |
Imipramine treatment of panic disorder in a boy with Tourette's syndrome.
Topics: Age Factors; Anxiety Disorders; Child, Preschool; Fear; Humans; Imipramine; Male; Panic; Phobic Diso | 1988 |