Page last updated: 2024-10-29

imipramine and Stress Disorders, Post-Traumatic

imipramine has been researched along with Stress Disorders, Post-Traumatic in 16 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Stress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month.

Research Excerpts

ExcerptRelevanceReference
"Imipramine was more effective than chloral hydrate in treating ASD symptoms (chi 2 [1, N = 25] = 5."2.69Imipramine treatment in pediatric burn patients with symptoms of acute stress disorder: a pilot study. ( Blakeney, PE; Meyer, WJ; Robert, R; Rosenberg, L; Villarreal, C, 1999)
"Both medications reduced PTSD symptoms."2.66A randomized clinical trial of phenelzine and imipramine for posttraumatic stress disorder. ( Dan, E; Frank, JB; Giller, EL; Kosten, TR, 1988)
"Post-traumatic stress disorder (PTSD) displays high co-morbidity with major depression and treatment-resistant depression (TRD)."1.46Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression II: response to antidepressant augmentation strategies. ( Brand, SJ; Harvey, BH, 2017)
"Posttraumatic stress disorder (PTSD) is frequently associated with major depressive disorder, and antidepressants have been reported to ameliorate PTSD symptoms in some patients."1.29Platelet imipramine binding in patients with posttraumatic stress disorder before and after phenelzine treatment. ( Abramovitz-Schnaider, P; Freudstein-Dan, A; Laor, N; Rehavi, M; Schujovitsky, A; Weizman, R; Wolmer, L, 1996)
"Because PTSD may become chronic and difficult to treat if unrecognized, early intervention is desirable."1.27Treatment of acute posttraumatic stress disorder with tricyclic antidepressants. ( Blake, DJ, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's4 (25.00)18.2507
2000's1 (6.25)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brand, SJ2
Harvey, BH2
Strawn, JR1
Keeshin, BR1
DelBello, MP1
Geracioti, TD1
Putnam, FW1
Huemer, J1
Erhart, F1
Steiner, H1
Wagner, KD1
Burstein, A1
Gillette, DW1
Tannery, LP1
Weizman, R1
Laor, N1
Schujovitsky, A1
Wolmer, L1
Abramovitz-Schnaider, P1
Freudstein-Dan, A1
Rehavi, M1
Robert, R1
Blakeney, PE1
Villarreal, C1
Rosenberg, L1
Meyer, WJ1
Damore, JP1
Kosten, TR2
Frank, JB2
Dan, E2
McDougle, CJ1
Giller, EL2
Kinzie, JD1
Leung, P1
Falcon, S1
Ryan, C1
Chamberlain, K1
Curtis, G1
Blake, DJ1
Mellman, TA1
Davis, GC1

Reviews

2 reviews available for imipramine and Stress Disorders, Post-Traumatic

ArticleYear
Psychopharmacologic treatment of posttraumatic stress disorder in children and adolescents: a review.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:7

    Topics: Adolescent; Adrenergic Antagonists; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Child; C

2010
Posttraumatic stress disorder in children and adolescents: a review of psychopharmacological treatment.
    Child psychiatry and human development, 2010, Volume: 41, Issue:6

    Topics: Adolescent; Antidepressive Agents; Child; Humans; Imipramine; Randomized Controlled Trials as Topic;

2010

Trials

4 trials available for imipramine and Stress Disorders, Post-Traumatic

ArticleYear
Imipramine treatment in pediatric burn patients with symptoms of acute stress disorder: a pilot study.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1999, Volume: 38, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Burn Units; Burns; Chi-Square Distribution; Child; Child, Preschoo

1999
Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine.
    The Journal of nervous and mental disease, 1991, Volume: 179, Issue:6

    Topics: Adult; Ambulatory Care; Anxiety; Depression; Double-Blind Method; Humans; Imipramine; Male; Personal

1991
A randomized clinical trial of phenelzine and imipramine for posttraumatic stress disorder.
    The American journal of psychiatry, 1988, Volume: 145, Issue:10

    Topics: Adult; Clinical Trials as Topic; Humans; Imipramine; Male; Phenelzine; Placebos; Psychiatric Status

1988
Tricyclics: possible treatment for posttraumatic stress disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:9

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Combat Disorders;

1985

Other Studies

10 other studies available for imipramine and Stress Disorders, Post-Traumatic

ArticleYear
Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression I: bio-behavioural validation and response to imipramine.
    Acta neuropsychiatrica, 2017, Volume: 29, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cerebral Cortex; Comorbidity; Depressiv

2017
Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression II: response to antidepressant augmentation strategies.
    Acta neuropsychiatrica, 2017, Volume: 29, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cerebral Cortex; Depressive Disorder, Treatment-Re

2017
Anxiety in youth.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:7

    Topics: Adolescent; Anxiety Disorders; Child; Comorbidity; Cross-Sectional Studies; Humans; Imipramine; Impl

2010
Treatment of post-traumatic stress disorder with imipramine.
    Psychosomatics, 1984, Volume: 25, Issue:9

    Topics: Dose-Response Relationship, Drug; Humans; Imipramine; Stress Disorders, Post-Traumatic

1984
Beta blocker inhibits tricyclic metabolism.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:2

    Topics: Adrenergic beta-Antagonists; Aggression; Anger; Antidepressive Agents, Tricyclic; Child; Depressive

1994
Platelet imipramine binding in patients with posttraumatic stress disorder before and after phenelzine treatment.
    Psychiatry research, 1996, Jul-31, Volume: 63, Issue:2-3

    Topics: Adult; Agoraphobia; Anxiety Disorders; Binding Sites; Blood Platelets; Depressive Disorder; Humans;

1996
Imipramine in burn patients.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2000, Volume: 39, Issue:1

    Topics: Acute Disease; Antidepressive Agents, Tricyclic; Burns; Child; Child, Preschool; Humans; Imipramine;

2000
Clonidine in Cambodian patients with posttraumatic stress disorder.
    The Journal of nervous and mental disease, 1989, Volume: 177, Issue:9

    Topics: Adult; Cambodia; Clonidine; Depressive Disorder; Drug Combinations; Female; Humans; Imipramine; Male

1989
Treatment of acute posttraumatic stress disorder with tricyclic antidepressants.
    Southern medical journal, 1986, Volume: 79, Issue:2

    Topics: Accidents, Occupational; Accidents, Traffic; Acute Disease; Adult; Antidepressive Agents, Tricyclic;

1986
Combat-related flashbacks in posttraumatic stress disorder: phenomenology and similarity to panic attacks.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:9

    Topics: Adult; Affect; Anxiety Disorders; Combat Disorders; Delusions; Fear; Hallucinations; Humans; Imipram

1985