Page last updated: 2024-10-29

imipramine and Spasm

imipramine has been researched along with Spasm in 7 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"On treatment with imipramine, wild-type mice became sedated and produced imipramine N-oxide in the brain and other tissues."1.35Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine. ( Chandan, P; Hernandez, D; Janmohamed, A; Omar, BA; Phillips, IR; Shephard, EA, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crooks, PA1
Rosenberg, HE1
Hernandez, D1
Janmohamed, A1
Chandan, P1
Omar, BA1
Phillips, IR1
Shephard, EA1
KANE, FJ1
TAYLOR, TW1
JOHNSON, MH1
BOUCHER, JV1
HILLS, NF1
Dean, G1
Thiemann, HH1
Otto, L1
Fritz, H1

Trials

1 trial available for imipramine and Spasm

ArticleYear
A double-blind trial with an antidepressant drug, imipramine, in multiple sclerosis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Jan-25, Volume: 43, Issue:4

    Topics: Clinical Trials as Topic; Depression; Humans; Imipramine; Multiple Sclerosis; Placebos; Spasm

1969

Other Studies

6 other studies available for imipramine and Spasm

ArticleYear
Synthesis of spiro[tetralin-2,2'-pyrrolidine] and spiro[indan-2,2'-pyrrolidine] derivatives as potential analgesics.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:6

    Topics: Acetates; Analgesics; Animals; Antidepressive Agents; Hypothermia; Indans; Indenes; Mice; Naphthalen

1978
Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.
    Pharmacogenetics and genomics, 2009, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cells, Cultured; Chromosomes; Embryonic

2009
An unusual reaction to combined imipramine-thorazine therapy.
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Chlorpromazine; Imipramine; Reflex; Spasm; Speech Disorders; Tremor

1963
A FATALITY ASSOCIATED WITH ANTIDEPRESSANT THERAPY.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Antidepressive Agents; Black People; Geriatrics; Humans; Imipramine; Psychotherapy; Seizures; Spasm;

1964
COMBINING THE ANTIDEPRESSANT DRUGS.
    British medical journal, 1965, Mar-27, Volume: 1, Issue:5438

    Topics: Anorexia Nervosa; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Fever; Heada

1965
[Fatal poisoning with imipramine].
    Das Deutsche Gesundheitswesen, 1967, Sep-07, Volume: 22, Issue:36

    Topics: Electrocardiography; Heart; Humans; Imipramine; Infant; Male; Respiration; Spasm; Unconsciousness

1967