imipramine has been researched along with Somatoform Disorders in 15 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Somatoform Disorders: Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by another medical condition, by the direct effects of a substance, or by another mental disorder. The MEDICALLY UNEXPLAINED SYMPTOMS must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study describes a sequential analysis of depression-related physical symptoms and their relationship to imipramine and amitriptyline plasma levels over 4 weeks of treatment in 79 unipolar and bipolar patients hospitalized for major depressive disorder." | 9.07 | The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine. ( Bowden, CL; Casper, RC; Davis, JM; Hanin, I; Katz, MM; Koslow, SH, 1994) |
| " We aimed to assess the effect of the tricyclic antidepressant, imipramine, in patients with multiple functional somatic syndromes defined by the criteria for multiorgan bodily distress syndrome, a unifying diagnosis that encompasses most functional somatic syndromes and somatoform disorders." | 5.24 | Imipramine versus placebo for multiple functional somatic syndromes (STreSS-3): a double-blind, randomised study. ( Agger, JL; Fink, PK; Gormsen, LK; Jensen, JS; Jensen, TS; Schröder, A, 2017) |
| "The study describes a sequential analysis of depression-related physical symptoms and their relationship to imipramine and amitriptyline plasma levels over 4 weeks of treatment in 79 unipolar and bipolar patients hospitalized for major depressive disorder." | 5.07 | The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine. ( Bowden, CL; Casper, RC; Davis, JM; Hanin, I; Katz, MM; Koslow, SH, 1994) |
| "The prognosis of treated hypochondriasis is good in a substantial proportion of patients." | 1.27 | Functional somatic symptoms and hypochondriasis. A survey of empirical studies. ( Kellner, R, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agger, JL | 1 |
| Schröder, A | 1 |
| Gormsen, LK | 1 |
| Jensen, JS | 1 |
| Jensen, TS | 1 |
| Fink, PK | 1 |
| Moore, A | 1 |
| Aldington, D | 1 |
| Mustafa, FA | 1 |
| Roberson-Nay, R | 1 |
| Latendresse, SJ | 1 |
| Kendler, KS | 1 |
| Fontenelle, LF | 1 |
| Mendlowicz, MV | 1 |
| Mussi, TC | 1 |
| Marques, C | 1 |
| Versiani, M | 1 |
| LAINE, E | 1 |
| LINQUETTE, M | 1 |
| FOSSATI, P | 1 |
| Karp, JF | 1 |
| Scott, J | 1 |
| Houck, P | 1 |
| Reynolds, CF | 1 |
| Kupfer, DJ | 1 |
| Frank, E | 1 |
| Brotman, AW | 1 |
| Jenike, MA | 1 |
| Frances, A | 1 |
| Petti, TA | 1 |
| Maany, I | 1 |
| Casper, RC | 1 |
| Katz, MM | 1 |
| Bowden, CL | 1 |
| Davis, JM | 1 |
| Koslow, SH | 1 |
| Hanin, I | 1 |
| Fisch, RZ | 1 |
| Kellner, R | 1 |
| Davidson, J | 1 |
| Pelton, S | 1 |
| Dollfus, S | 1 |
| Petit, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Multi-organ Bodily Distress Syndrome. A Double-blinded Placebo Controlled Trial of the Effects of Imipramine (Stress-3)[NCT01518634] | Phase 2 | 138 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for imipramine and Somatoform Disorders
| Article | Year |
|---|---|
Imipramine versus placebo for multiple functional somatic syndromes (STreSS-3): a double-blind, randomised study.
Topics: Adult; Antidepressive Agents, Tricyclic; Denmark; Double-Blind Method; Female; Humans; Imipramine; L | 2017 |
The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine.
Topics: Adult; Affect; Amitriptyline; Appetite; Arousal; Bipolar Disorder; Body Weight; Depressive Disorder; | 1994 |
Forms of atypical depression and their response to antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorders; Bupropion; Clinical Trial | 1986 |
12 other studies available for imipramine and Somatoform Disorders
| Article | Year |
|---|---|
Low dose imipramine for multiple functional somatic syndromes.
Topics: Double-Blind Method; Humans; Imipramine; Somatoform Disorders; Syndrome | 2017 |
Imipramine for multiple functional somatic syndromes.
Topics: Depression; Double-Blind Method; Humans; Imipramine; Somatoform Disorders; Syndrome | 2017 |
A latent class approach to the external validation of respiratory and non-respiratory panic subtypes.
Topics: Age of Onset; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Diagnostic and Statistical Man | 2012 |
The man with the purple nostrils: a case of rhinotrichotillomania secondary to body dysmorphic disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Tricyclic; Body Image; Disruptive, Impul | 2002 |
[Action of injectable imipramine in painful syndromes].
Topics: Humans; Imipramine; Pain; Somatoform Disorders; Syndrome | 1962 |
Pain predicts longer time to remission during treatment of recurrent depression.
Topics: Antidepressive Agents, Tricyclic; Combined Modality Therapy; Comorbidity; Depressive Disorder; Femal | 2005 |
Monosymptomatic hypochondriasis treated with tricyclic antidepressants.
Topics: Adult; Delusions; Doxepin; Female; Humans; Hypochondriasis; Imipramine; Male; Somatoform Disorders | 1984 |
Boy with seriously ill mother manifests somatic complaints, withdrawal, disabling fears.
Topics: Adjustment Disorders; Child; Child Reactive Disorders; Combined Modality Therapy; Desipramine; Famil | 1984 |
Treatment of depression associated with Briquet's syndrome.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depressive Disorder; Female; Humans; Imipramine; Male; | 1981 |
Alexithymia, masked depression and loss in a Holocaust survivor.
Topics: Affective Symptoms; Concentration Camps; Depressive Disorder; Female; Follow-Up Studies; Grief; Huma | 1989 |
Functional somatic symptoms and hypochondriasis. A survey of empirical studies.
Topics: Anti-Anxiety Agents; Attitude to Health; Benzodiazepines; Conditioning, Psychological; Culture; Diag | 1985 |
[Chemotherapy principles of severe somatic expressions of anxiety in adolescents].
Topics: Adolescent; Alprazolam; Anxiety; Female; Humans; Imipramine; Somatoform Disorders | 1988 |