imipramine has been researched along with Sleep Initiation and Maintenance Disorders in 23 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examine whether baseline anxiety or insomnia symptoms (1) show differential response to fluoxetine or imipramine or (2) predict differences between drugs in overall clinical response or likelihood of medication discontinuation." | 2.69 | Should anxiety and insomnia influence antidepressant selection: a randomized comparison of fluoxetine and imipramine. ( Grothaus, L; Heiligenstein, JH; Katon, W; Revicki, D; Simon, GE, 1998) |
| " Therapy was initiated at 50 mg/day; thereafter, dosage ranged between 100 and 300 mg/day for both drugs." | 2.66 | A double-blind placebo-controlled study of fluvoxamine and imipramine in depression. ( Dominguez, RA; Goldstein, BJ; Jacobson, AF; Steinbook, RM, 1985) |
| " A metaregression did not reveal a statistically significant relation between the mean moclobemide dosage for each study and the risk ratio for response rates." | 2.43 | A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. ( Fava, M; Papakostas, GI, 2006) |
| "Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis." | 2.37 | Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986) |
| "Imipramine also improved the boy's insomnia and enuresis, whereas methylphenidate caused an overall worsening of his condition." | 1.28 | Imipramine treatment of ADHD in a fragile X child. ( Hall, BD; Heffron, WM; Hilton, DK; Johnson, GL; Martin, CA, 1991) |
| "Desipramine was associated with a much higher frequency of jitteriness than was imipramine." | 1.27 | The jitteriness syndrome in panic disorder patients treated with antidepressants. ( Balon, R; Lycaki, H; Pohl, R; Yeragani, VK, 1988) |
| "Significant withdrawal symptoms were found over seven symptom categories despite an average tapering period of 6." | 1.26 | Withdrawal symptoms after graduated cessation of imipramine in children. ( Kazdin, AE; Law, W; Petti, TA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (82.61) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LINN, L | 1 |
| DELAY, J | 1 |
| DENIKER, P | 1 |
| HILLS, NF | 1 |
| Papakostas, GI | 1 |
| Fava, M | 1 |
| Law, W | 1 |
| Petti, TA | 1 |
| Kazdin, AE | 1 |
| Balon, R | 2 |
| Simon, GE | 1 |
| Heiligenstein, JH | 1 |
| Grothaus, L | 1 |
| Katon, W | 1 |
| Revicki, D | 1 |
| White, JH | 1 |
| Schnaultz, NL | 1 |
| Hilton, DK | 1 |
| Martin, CA | 1 |
| Heffron, WM | 1 |
| Hall, BD | 1 |
| Johnson, GL | 1 |
| McDaniel, KD | 1 |
| Ware, JC | 1 |
| Brown, FW | 1 |
| Moorad, PJ | 1 |
| Pittard, JT | 1 |
| Cobert, B | 1 |
| Pohl, R | 1 |
| Yeragani, VK | 1 |
| Lycaki, H | 1 |
| Cohn, JB | 1 |
| Wilcox, C | 1 |
| Stark, P | 1 |
| Hardison, CD | 1 |
| Dominguez, RA | 1 |
| Goldstein, BJ | 1 |
| Jacobson, AF | 1 |
| Steinbook, RM | 1 |
| Thomas, HB | 1 |
| Zung, WW | 1 |
| Zarcone, V | 1 |
| Pearlman, CA | 1 |
| Greenberg, R | 1 |
| Rickels, K | 1 |
| Chung, HR | 1 |
| Csanalosi, I | 1 |
| Sablosky, L | 1 |
| Simon, JH | 1 |
| Waizer, J | 1 |
| Hoffman, SP | 1 |
| Polizos, P | 1 |
| Engelhardt, DM | 1 |
| Kessell, A | 1 |
| Pearce, TA | 1 |
| Holt, NF | 1 |
| Edwards, G | 1 |
5 reviews available for imipramine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.
Topics: Depressive Disorder, Major; Disorders of Excessive Somnolence; Fatigue; Headache; Humans; Imipramine | 2006 |
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention | 1986 |
The pharmacology of disordered sleep: a laboratory approach.
Topics: Amitriptyline; Anxiety; Arousal; Barbiturates; Brain; Cerebral Cortex; Depression; Desipramine; Huma | 1970 |
Narcolepsy.
Topics: Adolescent; Adult; Amphetamine; Cataplexy; Child; Diagnosis, Differential; Female; Hallucinations; H | 1973 |
Medical-psychological implications of recent sleep research.
Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd | 1970 |
9 trials available for imipramine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Should anxiety and insomnia influence antidepressant selection: a randomized comparison of fluoxetine and imipramine.
Topics: Adult; Aged; Anxiety Disorders; Comorbidity; Depressive Disorder; Drug Administration Schedule; Fema | 1998 |
Effects on sleep: a double-blind study comparing trimipramine to imipramine in depressed insomniac patients.
Topics: Adolescent; Adult; Depressive Disorder; Dibenzazepines; Double-Blind Method; Electroencephalography; | 1989 |
A comparison of fluoxetine, imipramine, and placebo in patients with major depressive disorder.
Topics: Adult; Ambulatory Care; Anxiety; Body Weight; Clinical Trials as Topic; Depressive Disorder; Dizzine | 1985 |
A review of multicenter controlled studies of fluoxetine vs. imipramine and placebo in outpatients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Ambulatory Care; Anxiety; Clinical Trials as Topic | 1985 |
A double-blind placebo-controlled study of fluvoxamine and imipramine in depression.
Topics: Adult; Aged; Ambulatory Care; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; | 1985 |
Iprindole and imipramine in non-psychotic depressed out-patients.
Topics: Adult; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Family Practice; Female | 1973 |
Outpatient treatment of hyperactive school children with imipramine.
Topics: Ambulatory Care; Child; Child Behavior Disorders; Child Psychiatry; Clinical Trials as Topic; Drug E | 1974 |
A controlled study of nortriptyline and imipramine.
Topics: Anxiety; Body Weight; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Nortriptylin | 1970 |
Comparison of the effect of imipramine and desipramine on some symptoms of depressive illness.
Topics: Adult; Anorexia Nervosa; Anxiety; Clinical Trials as Topic; Depression; Desipramine; Humans; Imipram | 1965 |
9 other studies available for imipramine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
THE USE OF DRUGS IN PSYCHOTHERAPY.
Topics: Antidepressive Agents; Barbiturates; Central Nervous System; Depression; Electroconvulsive Therapy; | 1964 |
[THE SECONDARY EFFECTS OF NEUROLEPTICS].
Topics: Antipsychotic Agents; Chlorpromazine; Fluphenazine; Humans; Hypotension; Imipramine; Methotrimeprazi | 1964 |
COMBINING THE ANTIDEPRESSANT DRUGS.
Topics: Anorexia Nervosa; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Fever; Heada | 1965 |
Withdrawal symptoms after graduated cessation of imipramine in children.
Topics: Anorexia; Child; Depressive Disorder; Fatigue; Female; Gastrointestinal Diseases; Headache; Humans; | 1981 |
Sleep terror disorder and insomnia treated with trazodone: a case report.
Topics: Child; Female; Humans; Hydroxyzine; Imipramine; Sleep Initiation and Maintenance Disorders; Sleep Wa | 1994 |
Successful treatment of anorexia nervosa with imipramine.
Topics: Adolescent; Anorexia Nervosa; Depression; Female; Humans; Imipramine; Male; Sleep Initiation and Mai | 1977 |
Imipramine treatment of ADHD in a fragile X child.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship, Drug; Drug Adminis | 1991 |
The jitteriness syndrome in panic disorder patients treated with antidepressants.
Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Diso | 1988 |
Hypnotics and hangovers.
Topics: Antidepressive Agents; Depression; Humans; Hypnotics and Sedatives; Imipramine; Sleep Initiation and | 1971 |