imipramine has been researched along with Serotonin Syndrome in 4 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case report describes a patient on tranylcypromine who erroneously received a single dose of imipramine and subsequently developed a fatal serotonin syndrome." | 3.72 | Fatal interaction between tranylcypromine and imipramine. ( Birkenhager, TK; Otte, W; van den Broek, WW, 2003) |
| "Serotonin syndrome (SS) and neuroleptic malignant syndrome (NMS) are life-threatening adverse reactions caused by serotonergic antidepressants and neuroleptics, respectively." | 1.42 | Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes. ( Nisijima, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nisijima, K | 1 |
| Otte, W | 1 |
| Birkenhager, TK | 1 |
| van den Broek, WW | 1 |
| Izumi, T | 1 |
| Iwamoto, N | 1 |
| Kitaichi, Y | 1 |
| Kato, A | 1 |
| Inoue, T | 1 |
| Koyama, T | 1 |
| Borsini, F | 1 |
| Brambilla, A | 1 |
| Cesana, R | 1 |
| Grippa, N | 1 |
4 other studies available for imipramine and Serotonin Syndrome
| Article | Year |
|---|---|
Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes.
Topics: Antidepressive Agents, Tricyclic; Clinical Decision-Making; Cyproheptadine; Dantrolene; Depressive D | 2015 |
Fatal interaction between tranylcypromine and imipramine.
Topics: Adrenergic Uptake Inhibitors; Anti-Anxiety Agents; Depressive Disorder; Drug Interactions; Fatal Out | 2003 |
Effects of co-administration of antidepressants and monoamine oxidase inhibitors on 5-HT-related behavior in rats.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cyclopropanes; Drug Interactions; Imipramine; M | 2007 |
Lack of interaction between flibanserin and antidepressants in inducing serotonergic syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Secon | 2001 |