imipramine has been researched along with Sciatica in 3 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of long-term administration of imipramine, a tricyclic antidepressant, on the phosphorylation status of cyclic adenosine monophosphate-responsive element-binding protein (CREB), mitogen-activated protein kinase family members, and phospholipase γ-1 (PLCγ-1) was investigated in the dorsal horn of the spinal cord following peripheral nerve lesion." | 1.39 | Long-term antidepressant treatment inhibits neuropathic pain-induced CREB and PLCγ-1 phosphorylation in the mouse spinal cord dorsal horn. ( Cadetti, F; Franciosi, A; Kusuda, R; Lucas, G; Previdelli, K; Ravanelli, MI; Zanon, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kusuda, R | 1 |
| Ravanelli, MI | 1 |
| Cadetti, F | 1 |
| Franciosi, A | 1 |
| Previdelli, K | 1 |
| Zanon, S | 1 |
| Lucas, G | 1 |
| Kwasucki, J | 1 |
| Stepień, A | 1 |
| Maksymiuk, G | 1 |
| Olbrych-Karpińska, B | 1 |
| Chrzanowski, J | 1 |
1 trial available for imipramine and Sciatica
| Article | Year |
|---|---|
[Evaluation of analgesic action of fluvoxamine compared with efficacy of imipramine and tramadol for treatment of sciatica--open trial].
Topics: Adult; Aged; Analgesics, Opioid; Antidepressive Agents; Female; Fluvoxamine; Follow-Up Studies; Huma | 2002 |
2 other studies available for imipramine and Sciatica
| Article | Year |
|---|---|
Long-term antidepressant treatment inhibits neuropathic pain-induced CREB and PLCγ-1 phosphorylation in the mouse spinal cord dorsal horn.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Wester | 2013 |
[Imipramine in the treatment of chronic sciatic pains].
Topics: Adult; Drug Evaluation; Humans; Imipramine; Middle Aged; Pain; Sciatica | 1977 |