imipramine has been researched along with Pregnancy in 126 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although imipramine is one of the antidepressants that could be effective in the treatment of panic disorder, data on its usage for this diagnosis in the pregnancy period are limited." | 7.80 | Low-dose imipramine for treatment of panic disorder during pregnancy: a retrospective chart review. ( Askin, R; Gungor, B; Sahingoz, M; Uguz, F, 2014) |
| "Two women with panic disorder who continued to be symptomatic during pregnancy were successfully treated with low doses of imipramine." | 7.68 | Imipramine treatment of panic disorder during pregnancy. ( DeVane, CL; Ware, MR, 1990) |
| "Platelet 3H-imipramine binding was examined in a cross-sectional study of 70 Caucasian women in pregnancy and the early post-partum period, and in 23 nonpregnant women of childbearing age." | 7.67 | Platelet 3H-imipramine binding in pregnancy and the puerperium. ( Bourke, MP; Horton, RW; Katona, CL; Kelly, JS; Missouris, CG; Moncrieff, D; Paykel, ES; Theodorou, AE, 1985) |
| "A growing body of evidence has focused on the impact of mitochondrial disturbances in the development of depression, but little data exist regarding the effects of chronic administration of antidepressant drugs on the brain's mitochondrial protein profile." | 5.43 | The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E, 2016) |
| "Bromocriptine is a dopamine agonist with potential mental side effects." | 5.26 | Bromocriptine associated with symptom exacerbation during neuroleptic treatment of schizoaffective schizophrenia. ( Frye, PE; Kim, MH; O'Shaughnessy, RW; Pariser, SF, 1982) |
| "Our goal was to find out the impact of two antidepressant drugs with various mechanisms of action - imipramine and fluoxetine, on the frontal cortex mitochondria-enriched fraction in an animal model of depression based on the prenatal stress procedure." | 3.88 | Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment. ( Basta-Kaim, A; Chamera, K; Głombik, K; Kotarska, K; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2018) |
| "Although imipramine is one of the antidepressants that could be effective in the treatment of panic disorder, data on its usage for this diagnosis in the pregnancy period are limited." | 3.80 | Low-dose imipramine for treatment of panic disorder during pregnancy: a retrospective chart review. ( Askin, R; Gungor, B; Sahingoz, M; Uguz, F, 2014) |
| "Fifteen female rats were separated into three groups (n = 5) and treated with 10 mg/kg/day of test substances on the ninth, tenth and eleventh day of pregnancy: G1, fluoxetine; G2, imipramine hydrochloride; G3 (control), saline." | 3.76 | Effects of fluoxetine and imipramine in rat fetuses treated during a critical gestational period: a macro and microscopic study. ( Borato, CE; Costa, AM; Esteves, A; Swerts, CA; Swerts, MS, 2010) |
| " Maternal exposure to imipramine in a dose equivalent to the therapeutic dose per unit body weight induced hyperthermic response to chlorpromazine in the male offspring, while normal control rats showed a marked hypothermia." | 3.69 | Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring. ( Fujii, T, 1997) |
| " Further attacks after discharge were recognized as panic attacks, and resolved with the anti-depressant imipramine." | 3.68 | Panic disorder masquerading as pre-eclampsia. ( Benjamin, J; Benjamin, M, 1993) |
| "Two women with panic disorder who continued to be symptomatic during pregnancy were successfully treated with low doses of imipramine." | 3.68 | Imipramine treatment of panic disorder during pregnancy. ( DeVane, CL; Ware, MR, 1990) |
| "Imipramine hydrochloride was administered orally twice daily to 18 bonnet and 3 rhesus monkeys between days 23 and 45 of pregnancy for 1-3 or 18-22 days at 1, 2, and 10 times the recommended human dose." | 3.65 | Teratologic evaluation of imipramine hydrochloride in bonnet (Macaca radiata) and rhesus monkeys (Macaca mulatta). ( , 1975) |
| "Amoxapine was associated with significant neuroleptic activity in plasma." | 2.65 | Double-blind comparison of amoxapine and imipramine in the treatment of depressed patients. ( Cohen, BM; Curren, FC; Falk, WE; Gelenberg, AJ; Hicks, RH; Lydiard, RB; McCormick, MG; Wojcik, JD, 1984) |
| " On the other hand, little is known about the impact of chronic administration of various antidepressant drugs on the brain mitochondria, as a target for the pharmacotherapy of depression." | 1.46 | Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Chamera, K; Głombik, K; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2017) |
| "A growing body of evidence has focused on the impact of mitochondrial disturbances in the development of depression, but little data exist regarding the effects of chronic administration of antidepressant drugs on the brain's mitochondrial protein profile." | 1.43 | The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E, 2016) |
| " Input files require estimates of binding coefficients, first- and/or second-order metabolism constants, level of interaction between the two chemicals, and dosing information." | 1.30 | A computer model and program for xenobiotic disposition during pregnancy. ( Luecke, RH; Pearce, BA; Wosilait, WD; Young, JF, 1997) |
| "Very little is known about the pharmacokinetics of neuroleptic drugs in breast-feeding mothers and their infants or about possible adverse effects in the infants." | 1.30 | Neuroleptic drugs in breast-milk: a study of pharmacokinetics and of possible adverse effects in breast-fed infants. ( Craggs, M; Kumar, R; Smith, B; Yoshida, K, 1998) |
| "QUESTIONSeveral of my patients with psychiatric disorders are either planning to conceive or are already pregnant." | 1.30 | Counseling psychiatric patients about drug exposures during pregnancy. ( Einarson, A; Koren, G, 1998) |
| "Three mothers of infants with holoprosencephaly consumed alcohol heavily in pregnancy." | 1.28 | Holoprosencephaly as a possible embryonic alcohol effect. ( Andrews, WL; Ronen, GM, 1991) |
| "3H-imipramine binding was determined in freshly prepared intact platelets from 17 monozygotic (MZ) and 15 dizygotic (DZ) twin pairs, all of them male, adult, drug-free, and healthy volunteers." | 1.27 | 3H-imipramine binding in human platelets: a study in normal twins. ( Friedl, W; Propping, P, 1984) |
| "Imipramine (IMI) was administered s." | 1.27 | Effect of prenatal imipramine exposure on development of the postnatal rat heart and brain. ( Delongchamp, RR; Harmon, JR; Kimmel, GL; Webb, PJ, 1986) |
| " Maternal weight gained during the dosing period was decreased in a dose-related manner, but there were no dose-related differences in offspring body weights." | 1.27 | Early neurobehavioral and neurochemical alterations in rats prenatally exposed to imipramine. ( Ali, SF; Buelke-Sam, J; Newport, GD; Slikker, W, 1986) |
| "Doxepin was administered once daily during the first trimester (days 1-7), second trimester (days 8-14) or third trimester (days 15-21) of pregnancy, while imipramine was administered during the third trimester only." | 1.27 | Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny. ( Field, FP; Simpkins, JW; Soltis, EE; Torosian, G, 1985) |
| "Bromocriptine is a dopamine agonist with potential mental side effects." | 1.26 | Bromocriptine associated with symptom exacerbation during neuroleptic treatment of schizoaffective schizophrenia. ( Frye, PE; Kim, MH; O'Shaughnessy, RW; Pariser, SF, 1982) |
| " Antenatal patients taking a once-daily dosage of prophylactic iron were more co-operative than those taking divided dosages." | 1.25 | Drug defaulting in a general practice. ( Porter, AM, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (73.02) | 18.7374 |
| 1990's | 20 (15.87) | 18.2507 |
| 2000's | 5 (3.97) | 29.6817 |
| 2010's | 9 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Głombik, K | 4 |
| Stachowicz, A | 3 |
| Trojan, E | 4 |
| Olszanecki, R | 3 |
| Ślusarczyk, J | 4 |
| Suski, M | 2 |
| Chamera, K | 3 |
| Budziszewska, B | 3 |
| Lasoń, W | 3 |
| Basta-Kaim, A | 4 |
| Kotarska, K | 1 |
| de la Garza, AL | 1 |
| Garza-Cuellar, MA | 1 |
| Silva-Hernandez, IA | 1 |
| Cardenas-Perez, RE | 1 |
| Reyes-Castro, LA | 1 |
| Zambrano, E | 1 |
| Gonzalez-Hernandez, B | 1 |
| Garza-Ocañas, L | 1 |
| Fuentes-Mera, L | 1 |
| Camacho, A | 1 |
| Uguz, F | 1 |
| Sahingoz, M | 1 |
| Gungor, B | 1 |
| Askin, R | 1 |
| Kubera, M | 1 |
| Spedding, M | 1 |
| Green, AD | 1 |
| Barr, AM | 1 |
| Galea, LA | 1 |
| Swerts, CA | 1 |
| Costa, AM | 1 |
| Esteves, A | 1 |
| Borato, CE | 1 |
| Swerts, MS | 1 |
| Yanpallewar, SU | 1 |
| Fernandes, K | 1 |
| Marathe, SV | 1 |
| Vadodaria, KC | 1 |
| Jhaveri, D | 1 |
| Rommelfanger, K | 1 |
| Ladiwala, U | 1 |
| Jha, S | 1 |
| Muthig, V | 1 |
| Hein, L | 1 |
| Bartlett, P | 1 |
| Weinshenker, D | 1 |
| Vaidya, VA | 1 |
| Réus, GZ | 1 |
| Dos Santos, MA | 1 |
| Abelaira, HM | 1 |
| Ribeiro, KF | 1 |
| Petronilho, F | 1 |
| Vuolo, F | 1 |
| Colpo, GD | 1 |
| Pfaffenseller, B | 1 |
| Kapczinski, F | 1 |
| Dal-Pizzol, F | 1 |
| Quevedo, J | 1 |
| ROBSON, JM | 2 |
| SULLIVAN, FM | 1 |
| BEGHI, Q | 1 |
| LARSEN, V | 1 |
| VIUKARI, M | 1 |
| KLEIN, JJ | 1 |
| SEGAL, RL | 1 |
| WARNER, RR | 1 |
| FRATTA, I | 1 |
| ZAK, SB | 1 |
| GREENGARD, P | 1 |
| SIGG, EB | 1 |
| Morley-Fletcher, S | 1 |
| Darnaudéry, M | 1 |
| Mocaer, E | 1 |
| Froger, N | 1 |
| Lanfumey, L | 1 |
| Laviola, G | 1 |
| Casolini, P | 1 |
| Zuena, AR | 1 |
| Marzano, L | 1 |
| Hamon, M | 1 |
| Maccari, S | 1 |
| Bhargava, KP | 2 |
| Gupta, ML | 1 |
| Douglas, BH | 2 |
| Hume, AS | 2 |
| Elliott, JM | 1 |
| Berrettini, WH | 1 |
| Goldin, LR | 1 |
| Nurnberger, JI | 1 |
| Gershon, ES | 1 |
| Jason, KM | 1 |
| Cooper, TB | 1 |
| Friedman, E | 1 |
| De Montis, GM | 1 |
| Devoto, P | 1 |
| Angioi, RM | 1 |
| Curreli, V | 1 |
| Tagliamonte, A | 1 |
| Friedl, W | 1 |
| Propping, P | 1 |
| Tuchmann-Duplessis, H | 1 |
| Gelenberg, AJ | 1 |
| Wojcik, JD | 1 |
| Lydiard, RB | 1 |
| McCormick, MG | 1 |
| Falk, WE | 1 |
| Hicks, RH | 1 |
| Curren, FC | 1 |
| Cohen, BM | 1 |
| Stout, SA | 2 |
| DeVane, CL | 4 |
| Simpkins, JW | 3 |
| Williams, DE | 1 |
| Ziegler, DM | 1 |
| Nordin, DJ | 1 |
| Hale, SE | 1 |
| Masters, BS | 1 |
| Das, S | 1 |
| Datta, SC | 1 |
| Guin, AK | 1 |
| Dey, S | 1 |
| Sengupta, D | 1 |
| Christ, W | 1 |
| Hecker, W | 1 |
| Gindler, K | 1 |
| Stille, G | 1 |
| Benesová, O | 1 |
| Shrand, H | 1 |
| Frye, PE | 1 |
| Pariser, SF | 1 |
| Kim, MH | 1 |
| O'Shaughnessy, RW | 1 |
| Ramamoorthy, S | 1 |
| Ramamoorthy, JD | 1 |
| Prasad, PD | 1 |
| Bhat, GK | 1 |
| Mahesh, VB | 2 |
| Leibach, FH | 2 |
| Ganapathy, V | 2 |
| Turner, RM | 1 |
| Love, CC | 1 |
| McDonnell, SM | 1 |
| Sweeney, RW | 1 |
| Twitchell, ED | 1 |
| Habecker, PL | 1 |
| Reilly, LK | 1 |
| Pozor, MA | 1 |
| Kenney, RM | 1 |
| Benjamin, J | 1 |
| Benjamin, M | 1 |
| Altshuler, LL | 1 |
| Hendrick, VC | 1 |
| Card, CE | 1 |
| Manning, ST | 1 |
| Bowman, P | 1 |
| Leibel, T | 1 |
| Luecke, RH | 1 |
| Wosilait, WD | 1 |
| Pearce, BA | 1 |
| Young, JF | 1 |
| Dirken, JJ | 1 |
| Cleine, JH | 1 |
| Yoshida, K | 1 |
| Smith, B | 1 |
| Craggs, M | 1 |
| Kumar, R | 1 |
| Fujii, T | 2 |
| Einarson, A | 1 |
| Koren, G | 1 |
| Ochsenkühn, R | 1 |
| Kamischke, A | 1 |
| Nieschlag, E | 1 |
| Alonso, SJ | 1 |
| Castellano, MA | 1 |
| Quintero, M | 1 |
| Navarro, E | 1 |
| Mortensen, OV | 1 |
| Kristensen, AS | 1 |
| Rudnick, G | 1 |
| Wiborg, O | 1 |
| Zafar, H | 1 |
| Shelat, SG | 1 |
| Redei, E | 1 |
| Tejani-Butt, S | 1 |
| Vedernikov, Y | 1 |
| Bolanos, S | 1 |
| Bytautiene, E | 1 |
| Fulep, E | 1 |
| Saade, GR | 1 |
| Garfield, RE | 1 |
| Standley, PR | 1 |
| Standley, CA | 1 |
| Rumeau-Rouquette, C | 1 |
| Goujard, J | 1 |
| Huel, G | 1 |
| Broitman, ST | 1 |
| Donoso, AO | 1 |
| Siris, SG | 1 |
| Chertoff, HR | 1 |
| Perel, JM | 1 |
| Singh, M | 1 |
| Tandon, R | 1 |
| Mason, BD | 1 |
| Van Petten, GR | 1 |
| Schloot, W | 1 |
| Goedde, HW | 1 |
| Fickentscher, K | 1 |
| Köhler, F | 1 |
| Coyle, IR | 3 |
| Singer, G | 3 |
| Rise, A | 1 |
| Romero, G | 1 |
| Toscano, E | 1 |
| Montero, D | 2 |
| De Felipe, MC | 1 |
| Del Rio, J | 2 |
| Shimizu, M | 1 |
| Nishida, A | 1 |
| Yamawaki, S | 1 |
| Schultz, JE | 1 |
| Rösch, H | 1 |
| Ronen, GM | 1 |
| Andrews, WL | 1 |
| de Ceballos, ML | 1 |
| Ware, MR | 1 |
| Abel, EL | 1 |
| Bilitzke, P | 1 |
| Harmon, JR | 1 |
| Webb, PJ | 1 |
| Kimmel, GL | 1 |
| Delongchamp, RR | 1 |
| Balkovetz, DF | 1 |
| Tiruppathi, C | 1 |
| Ali, SF | 1 |
| Buelke-Sam, J | 1 |
| Newport, GD | 1 |
| Slikker, W | 1 |
| Wood, M | 1 |
| Meerbach, W | 1 |
| Gräbner, R | 1 |
| Müller, U | 1 |
| Zimmermann, W | 1 |
| Katona, CL | 1 |
| Theodorou, AE | 1 |
| Missouris, CG | 1 |
| Bourke, MP | 1 |
| Horton, RW | 1 |
| Moncrieff, D | 1 |
| Paykel, ES | 1 |
| Kelly, JS | 1 |
| Field, FP | 1 |
| Torosian, G | 1 |
| Soltis, EE | 1 |
| Ohtaki, Y | 1 |
| Idänpään-Heikkilä, J | 1 |
| Saxén, L | 1 |
| Eggermont, E | 2 |
| Tonge, SR | 3 |
| Daly, RJ | 1 |
| Kane, FJ | 1 |
| Ewing, JA | 1 |
| Kaufmann, JS | 1 |
| Lanza, M | 1 |
| Chichmanian, RM | 1 |
| Goude, F | 1 |
| Sim, M | 1 |
| Lewis, DO | 1 |
| Morrow, AW | 3 |
| Gupta, MB | 1 |
| Tangri, KK | 1 |
| Shapiro, IuL | 1 |
| Vaĭntrub, MIa | 1 |
| Grinberg, KN | 1 |
| Zhurkov, VS | 1 |
| Wilson, JG | 1 |
| Raveschot, J | 1 |
| Deneve, V | 1 |
| Casteels-van Daele, M | 1 |
| Rowe, IL | 1 |
| Leonard, BE | 1 |
| Sarteschi, P | 1 |
| Cassano, GB | 1 |
| Placidi, GF | 1 |
| Stern, JJ | 1 |
| Zwick, G | 1 |
| Rapoport, JL | 1 |
| Quinn, PO | 1 |
| Lamprecht, F | 1 |
| Crimson, C | 1 |
| Crombie, DL | 1 |
| Pinsent, RJ | 1 |
| Fleming, D | 1 |
| Barson, AJ | 1 |
| Kuenssberg, EV | 1 |
| Knox, JD | 1 |
| McBride, WG | 1 |
| Freeman, D | 1 |
| Hughes, WW | 1 |
| Jacobs, D | 1 |
| Rockey, T | 1 |
| Pitt, DB | 1 |
| Wilkins, GD | 1 |
| Levy, L | 1 |
| Swan, E | 1 |
| Pruitt, AW | 1 |
| Dayton, PG | 1 |
| Simionescu, S | 1 |
| Bordeianu, A | 1 |
| Stancu, C | 1 |
| Slăvescu-Daniel, B | 1 |
| Pintilescu, V | 1 |
| Stainbrook, E | 1 |
| Radzuweit, H | 1 |
| Knorr, W | 1 |
| Scanlon, FJ | 1 |
| Aeppli, L | 1 |
| Lindström, LH | 1 |
| Porter, AM | 1 |
| Artner, J | 1 |
| Grabowsky, JR | 1 |
11 reviews available for imipramine and Pregnancy
| Article | Year |
|---|---|
THE PROBLEM OF TERATOGENICITY.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Cyclizine; Female; Imipramine; Nicotine; Preg | 1963 |
Platelet receptor binding studies in affective disorders.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Blood Plate | 1984 |
Genetic factors in affective illness.
Topics: ABO Blood-Group System; Blood Platelets; Cholinergic Fibers; Diseases in Twins; Female; gamma-Aminob | 1984 |
The teratogenic risk.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Amphetamine; Animals; Anticoagulants; Anticonv | 1983 |
[Are nervous system drugs teratogenic? Evaluation of epidemiologic studies].
Topics: Abnormalities, Drug-Induced; Amphetamines; Anticonvulsants; Antipsychotic Agents; Female; Humans; Im | 1976 |
[Psychopharmacogentics].
Topics: Adult; Animals; Antidepressive Agents, Tricyclic; Asian People; Dose-Response Relationship, Drug; Dr | 1976 |
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca | 1986 |
The pharmacodynamics of depression and its relation to therapy.
Topics: Adrenal Glands; Amitriptyline; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain Che | 1974 |
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent | 1972 |
Present status of drugs as teratogens in man.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics; | 1973 |
Chlorpromazine and imipramine: parallel studies in animals.
Topics: Animals; Animals, Newborn; Cats; Chlorpromazine; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Imip | 1967 |
2 trials available for imipramine and Pregnancy
| Article | Year |
|---|---|
Double-blind comparison of amoxapine and imipramine in the treatment of depressed patients.
Topics: Adolescent; Adult; Ambulatory Care; Amoxapine; Basal Ganglia Diseases; Clinical Trials as Topic; Dep | 1984 |
Imipramine for successful treatment of retrograde ejaculation caused by retroperitoneal surgery.
Topics: Adult; Antidepressive Agents, Tricyclic; Ejaculation; Female; Humans; Imipramine; Infertility, Male; | 1999 |
113 other studies available for imipramine and Pregnancy
| Article | Year |
|---|---|
Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression.
Topics: 14-3-3 Proteins; Animals; Antidepressive Agents; Cathepsin D; COP9 Signalosome Complex; Depression; | 2017 |
Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Female; Flu | 2018 |
Maternal Flavonoids Intake Reverts Depression-Like Behaviour in Rat Female Offspring.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Diet; Disaccharides; Drug Interactions | 2019 |
Low-dose imipramine for treatment of panic disorder during pregnancy: a retrospective chart review.
Topics: Adult; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Female; Humans; Imipramin | 2014 |
The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Depression; Disease Models, Animal; Electrophoresis, Gel, | 2016 |
Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment.
Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Female; Fluoxetine; Gene Expression; Imi | 2017 |
Role of estradiol withdrawal in 'anhedonic' sucrose consumption: a model of postpartum depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Depression, Postpartum; Disease M | 2009 |
Effects of fluoxetine and imipramine in rat fetuses treated during a critical gestational period: a macro and microscopic study.
Topics: Animals; Antidepressive Agents; Brain; Dopamine Uptake Inhibitors; Female; Fetal Weight; Fetus; Fluo | 2010 |
Alpha2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Ad | 2010 |
Imipramine reverses alterations in cytokines and BDNF levels induced by maternal deprivation in adult rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Brain; Brain-Derived Neurotrophic F | 2013 |
The production of foetal abnormalities in rabbits by imipramine.
Topics: Animals; Congenital Abnormalities; Female; Imipramine; Pregnancy; Pregnancy, Animal; Rabbits | 1963 |
[PSYCHIATRIC USE OF SOME PSYCHOPHARMACOLOGICAL DRUGS IN PREGNANCY].
Topics: Chlordiazepoxide; Chlorpromazine; Fetus; Haloperidol; Imipramine; Isocarboxazid; Meprobamate; Nialam | 1963 |
THE TERATOGENIC EFFECTS OF THALIDOMIDE, IMIPRAMINE HC1 AND IMIPRAMINE-N-OXIDE HC1 ON WHITE DANISH RABBITS.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Female; Fetal Diseases; Humans; Imipramine; | 1963 |
[RESULTS WITH PSYCHOTROPIC DRUGS IN OUTPATIENT TREATMENT].
Topics: Chlorpromazine; Depression; Depressive Disorder; Female; Humans; Imipramine; Iproniazid; Mental Diso | 1964 |
GALACTORRHEA DUE TO IMIPRAMINE. REPORT OF A CASE.
Topics: Amenorrhea; Chlorpromazine; Depression; Depressive Disorder; Female; Galactorrhea; Humans; Hypothyro | 1964 |
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
Topics: Animals; Avitaminosis; Chlorpromazine; Diet; Female; Fetal Death; Fetus; Imipramine; Liver; NAD; Nia | 1964 |
Chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-HT(1A) receptor mRNA in prenatally stressed rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Cerebral Cortex; Female; Hippocampus; Im | 2004 |
A study of central adrenergic mechanisms in the regulation of the oestrous cycle of albino mice.
Topics: Animals; Catecholamines; Estrus; Female; Imipramine; Methyldopa; Methyltyrosines; Mice; Monoamine Ox | 1966 |
Placental transfer of imipramine, a basic, lipid-soluble drug.
Topics: Animals; Female; Imipramine; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy, Animal; Rats | 1967 |
Prenatal exposure to imipramine alters early behavioral development and beta adrenergic receptors in rats.
Topics: Animals; Behavior, Animal; Brain; Catecholamines; Female; Growth; Imipramine; Maternal-Fetal Exchang | 1981 |
In utero exposure to methadone produces a stable decrease of the cortex 5-HT transport system in rats.
Topics: Animals; Biological Transport; Cerebral Cortex; Female; Imipramine; Methadone; Naloxone; Pregnancy; | 1983 |
3H-imipramine binding in human platelets: a study in normal twins.
Topics: Adult; Blood Platelets; Carrier Proteins; Female; Humans; Imipramine; Male; Pregnancy; Receptors, Dr | 1984 |
Quantification of imipramine and its major metabolites in whole blood, brain, and other tissues of the rat by liquid chromatography.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Desipramine; Female; Fetus; Imipramine; Pregna | 1984 |
Cerebral and blood pharmacokinetics of imipramine and its active metabolites in the pregnant rat.
Topics: Animals; Brain; Desipramine; Erythrocytes; Female; Imipramine; Kinetics; Male; Pregnancy; Rats; Rats | 1984 |
Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme.
Topics: Aniline Compounds; Animals; Chlorpromazine; Cross Reactions; Cysteamine; Female; Guinea Pigs; Imipra | 1984 |
Role of imipramine & desipramine in counteracting diazepam induced changes of adenosinetriphosphatase & cholinesterase of human fetal brain.
Topics: Adenosine Triphosphatases; Brain; Cholinesterases; Desipramine; Diazepam; Female; Fetus; Gestational | 1981 |
Phase I metabolism of imipramine by foetal liver of man and rhesus monkey.
Topics: Adolescent; Animals; Female; Fetus; Humans; Imipramine; Liver; Macaca mulatta; Pregnancy; Species Sp | 1983 |
To the pharmacological profile of maprotiline.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Anthracenes; Arousal; Chick Embryo; Depressive Disorder | 1982 |
Agoraphobia and imipramine withdrawal?
Topics: Agoraphobia; Female; Humans; Imipramine; Infant, Newborn; Infant, Newborn, Diseases; Phobic Disorder | 1982 |
Bromocriptine associated with symptom exacerbation during neuroleptic treatment of schizoaffective schizophrenia.
Topics: Adult; Amenorrhea; Bromocriptine; Drug Therapy, Combination; Female; Galactorrhea; Humans; Imipramin | 1982 |
Regulation of the human serotonin transporter by interleukin-1 beta.
Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Choriocarcinoma; Cocaine; Cyclic A | 1995 |
Use of imipramine hydrochloride for treatment of urospermia in a stallion with a dysfunctional bladder.
Topics: Abdominal Neoplasms; Adrenergic Uptake Inhibitors; Animals; Carcinoma, Transitional Cell; Female; Ho | 1995 |
Panic disorder masquerading as pre-eclampsia.
Topics: Adult; Diagnosis, Differential; Female; Humans; Imipramine; Panic Disorder; Postpartum Period; Pre-E | 1993 |
Pregnancy and psychotropic medication: changes in blood levels.
Topics: Adult; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Depressive Disorder; | 1996 |
Pregnancies from imipramine and xylazine-induced ex copula ejaculation in a disabled stallion.
Topics: Animals; Antidepressive Agents, Tricyclic; Breeding; Disabled Persons; Ejaculation; Female; Horses; | 1997 |
A computer model and program for xenobiotic disposition during pregnancy.
Topics: Animals; Computer Simulation; Desipramine; Female; Humans; Imipramine; Maternal-Fetal Exchange; Merc | 1997 |
[Retrograde ejaculation: a treatable fertility problem].
Topics: Adult; Ejaculation; Female; Fertilization in Vitro; Humans; Imipramine; Infertility, Male; Inseminat | 1997 |
Neuroleptic drugs in breast-milk: a study of pharmacokinetics and of possible adverse effects in breast-fed infants.
Topics: Adult; Antipsychotic Agents; Bottle Feeding; Breast Feeding; Child Development; Chlorpromazine; Chro | 1998 |
Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring.
Topics: Aggression; Aminobutyrates; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplast | 1997 |
Counseling psychiatric patients about drug exposures during pregnancy.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Tricyclic; Clonazepam; Embryonic and Fetal Developmen | 1998 |
Action of antidepressant drugs on maternal stress-induced hypoactivity in female rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationsh | 1999 |
Molecular cloning, expression and characterization of a bovine serotonin transporter.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; | 1999 |
Fetal alcohol exposure alters serotonin transporter sites in rat brain.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Autoradiography; Brain; Carrier Proteins; Female; F | 2000 |
Effect of fluoxetine on contractile activity of pregnant rat uterine rings.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Dose-Response Relationship, | 2000 |
Identification of a functional Na+/Mg2+ exchanger in human trophoblast cells.
Topics: Antidepressive Agents, Tricyclic; Antiporters; Choriocarcinoma; Female; Humans; Imipramine; Placenta | 2002 |
Effects of chronic imipramine and clomipramine oral administration on maternal behavior and litter development.
Topics: Animals; Body Weight; Clomipramine; Dibenzazepines; Female; Growth; Imipramine; Maternal Behavior; M | 1978 |
Rapid-cycling affective disorders during imipramine treatment: a case report.
Topics: Adult; Bipolar Disorder; Depression; Female; Humans; Imipramine; Periodicity; Pregnancy; Puerperal D | 1979 |
Transient left bundle branch block in a neonate.
Topics: Bundle-Branch Block; Female; Humans; Imipramine; Infant, Newborn; Infant, Newborn, Diseases; Materna | 1977 |
Effects of tricyclic antidepressants on cardiovascular responses to norepinephrine and phenylephrine during pregnancy.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Female; Imipramine; Norepi | 1978 |
Teratogenicity and embryotoxicity of some maleinimides.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Imides; Imipramine; Maleimides; Mice; Pht | 1976 |
Teratologic evaluation of imipramine hydrochloride in bonnet (Macaca radiata) and rhesus monkeys (Macaca mulatta).
Topics: Abortifacient Agents; Animals; Female; Gestational Age; Imipramine; Macaca mulatta; Macaca radiata; | 1975 |
The interaction of post-weaning housing conditions and prenatal drug effects on behaviour.
Topics: Animals; Behavior, Animal; Female; Fetus; Gestational Age; Imipramine; Learning; Motor Skills; Pregn | 1975 |
The interactive effects of prenatal imipramine exposure and postnatal rearing conditions on behaviour and histology.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Exploratory Behavior; Female; Fetus; Housing, An | 1975 |
[Antidepressive agents].
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Female; Humans; Imipramine; Infant, Newborn; Mat | 1976 |
Effect of prenatal exposure to tianeptine on different neurotransmitter receptors and 5-HT-stimulated inositol phosphate formation in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Female; Imipramine; Inositol Phospha | 1992 |
Antidepressants inhibit spontaneous oscillations of intracellular Ca2+ concentration in rat cortical cultured neurons.
Topics: Amitriptyline; Animals; Antidepressive Agents; Calcium; Cerebral Cortex; Dose-Response Relationship, | 1992 |
Differential effects of ovarian steroid hormones on beta-adrenoceptor downregulation caused by the antidepressants imipramine and rolipram.
Topics: Animals; Antidepressive Agents; Body Weight; Cerebral Cortex; Down-Regulation; Estrone; Female; Gona | 1991 |
Holoprosencephaly as a possible embryonic alcohol effect.
Topics: Abnormalities, Drug-Induced; Alcohol Drinking; Chlordiazepoxide; Female; Holoprosencephaly; Humans; | 1991 |
Down-regulation of 3H-imipramine binding sites in rat cerebral cortex after prenatal exposure to antidepressants.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Binding Sites; Carrier Proteins; Cerebral Cort | 1990 |
Imipramine treatment of panic disorder during pregnancy.
Topics: Adult; Anxiety Disorders; Female; Humans; Imipramine; Panic; Pregnancy; Pregnancy Complications; Pre | 1990 |
Paternal alcohol exposure: paradoxical effect in mice and rats.
Topics: Animals; Behavior, Animal; Corticosterone; Ethanol; Female; Imipramine; Male; Metergoline; Mice; Pre | 1990 |
Effect of prenatal imipramine exposure on development of the postnatal rat heart and brain.
Topics: Aging; Animals; Body Weight; Brain; Dihydroalprenolol; Eflornithine; Female; Heart; Imipramine; Litt | 1986 |
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes.
Topics: Carrier Proteins; Cations, Monovalent; Desipramine; Female; Humans; Hydralazine; Imipramine; Kinetic | 1989 |
Early neurobehavioral and neurochemical alterations in rats prenatally exposed to imipramine.
Topics: Analysis of Variance; Animals; Brain; Dextroamphetamine; Dihydroalprenolol; Female; Imipramine; Male | 1986 |
Influence of imipramine and chloroquine on lung phospholipid content and lung structure in newborn rats.
Topics: Animals; Chloroquine; Female; Fetal Organ Maturity; Gestational Age; Imipramine; Lung; Organ Size; P | 1987 |
Possible teratogenic effects of imipramine in the rat.
Topics: Animals; Dopamine; Estrus; Female; Hypothalamo-Hypophyseal System; Hypothalamus; Imipramine; Male; N | 1987 |
Platelet 3H-imipramine binding in pregnancy and the puerperium.
Topics: Adult; Blood Platelets; Emotions; Female; Humans; Imipramine; Postpartum Period; Pregnancy; Tritium | 1985 |
Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny.
Topics: Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Doxepin; Female; Gestational Age; Heart R | 1985 |
Sex-related hyperthermic response to chlorpromazine in the offspring of rats treated with imipramine.
Topics: Animals; Body Temperature; Chlorpromazine; Female; Growth; Imipramine; Male; Pregnancy; Prenatal Exp | 1985 |
Rachelefsky GS, Flynt JW Jr,+FLYNT JW JR, Ebbin AJ, Wilson MG, Banister P, Dafoe C, Smith ES, Miller J:Possible teratogenicity of tricyclic antidepressants.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Antidepressive Agents; Female; Humans; Imipramine; Infan | 1972 |
Possible teratogenicity of imipramine-chloropyramine.
Topics: Abnormalities, Drug-Induced; Adult; Amitriptyline; Antidepressive Agents; Benzyl Compounds; Drug Com | 1973 |
Withdrawal symptoms in neonates associated with maternal imipramine therapy.
Topics: Female; Fetus; Humans; Imipramine; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchan | 1973 |
Permanent changes in brain monoamine metabolism induced by the administration of psychotropic drugs during the pre- and neonatal periods in rats.
Topics: Animals; Ascorbic Acid; Brain; Brain Chemistry; Chlorpromazine; Female; Hydroxyindoleacetic Acid; Im | 1972 |
Catecholamine concentrations in discrete areas of the rat brain after the pre- and neonatal administration of phencyclidine and imipramine.
Topics: Amygdala; Animals; Animals, Newborn; Ascorbic Acid; Brain Chemistry; Catecholamines; Cerebellar Cort | 1973 |
Psychosis associated with the use of a sequential oral contraceptive.
Topics: Adult; Chlormadinone Acetate; Chlorpromazine; Contraceptives, Oral; Depression; Estrogens; Female; H | 1967 |
Letter: Pheochromocytoma and tricyclic antidepressants.
Topics: Adrenal Gland Neoplasms; Adult; Blood Vessels; Catecholamines; Depression; Epilepsy, Tonic-Clonic; F | 1974 |
[Action of various tricyclic antidepressive agents on the estrous cycle of the female rat].
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dibenzazepines; Estrus; Female; Imiprami | 1970 |
Imipramine and pregnancy.
Topics: Abnormalities, Drug-Induced; Depression; Down Syndrome; Female; Fetal Death; Humans; Imipramine; Pre | 1972 |
Imipramine and congenital abnormalities.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Female; Humans; Imipramine; Infant, Newborn; Limb Deform | 1972 |
Fetotoxicity.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Antidepressive Agents; Female; Human | 1972 |
Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cordotomy; Dose-Response Relationship, Drug; Femal | 1973 |
The adverse influence of imipramine on the adaptation of the newborn infant to extrauterine life.
Topics: Cyanosis; Depression; Female; Fetal Diseases; Fetus; Heart Failure; Humans; Imipramine; Infant, Newb | 1972 |
Prescriptions of psychotropic drugs by general practitioners. 2. Antidepressants.
Topics: Abnormalities, Drug-Induced; Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Antidepress | 1973 |
Some persistent effects of the pre- and neonatal administration of psychotropic drugs on noradrenaline metabolism in discrete areas of rat brain.
Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents; Brain; Cerebral Cortex; Chlorpromazine; | 1973 |
The effect of imipramine administered before and during pregnancy on litter size in the rat.
Topics: Animals; Animals, Newborn; Body Height; Embryo, Mammalian; Female; Fertility; Fetus; Imipramine; Pla | 1973 |
Placental penetration and foetal uptake of neuropharmacological agents.
Topics: Amitriptyline; Animals; Animals, Newborn; Autoradiography; Carbon Radioisotopes; Chlordiazepoxide; C | 1973 |
Effects of intraventricular norepinephrine and estradiol benzoate on weight regulatory behavior in female rats.
Topics: Animals; Body Weight; Brain Chemistry; Castration; Cerebral Ventricles; Darkness; Drug Synergism; Ea | 1973 |
Minor physical anomalies and plasma dopamine-beta-hydroxylase activity in hyperactive boys.
Topics: Abnormalities, Multiple; Child; Dopamine beta-Hydroxylase; Female; Humans; Hyperkinesis; Imipramine; | 1974 |
Imipramine in pregnancy.
Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Pregnancy; Time Factors | 1972 |
Malformed infant.
Topics: Abnormalities, Drug-Induced; Adult; Cleft Palate; Female; Fetal Death; Humans; Imipramine; Medical R | 1972 |
Imipramine in pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amitriptyline; Female; Humans; Imipramine; Infan | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Imipramine; Infant, Newborn; Pregnancy | 1972 |
Imipramine and pregnancy.
Topics: Female; Humans; Imipramine; Pregnancy; Pregnancy Complications | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Australia; Female; Humans; Imipramine; Infant, Newborn; Limb Deformitie | 1972 |
[False alarm?].
Topics: Abnormalities, Drug-Induced; Australia; Drug and Narcotic Control; Drug Prescriptions; Female; Human | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Australia; Female; Humans; Imipramine; Information Services; Pregnancy | 1972 |
Imipramine (tofranil).
Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Pregnancy | 1972 |
Imipramine (Tofranil).
Topics: Abnormalities, Drug-Induced; Drug Labeling; Female; Humans; Imipramine; Pregnancy | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Drug and Narcotic Control; Ectromelia; Female; Humans; I | 1972 |
Imipramine and fetal deformities.
Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Pregnancy | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Limb Deformities, Congenit | 1972 |
A comparison of the binding of drugs to adult and cord plasma.
Topics: Blood; Blood Proteins; Carbon Isotopes; Cephaloglycin; Cephalothin; Chromatography, Thin Layer; Dial | 1971 |
[Study of the non-specific pharmacodynamic action of psychotropic drug (Antideprin) synthesized in our country, on the equilibrium of sexual functions].
Topics: Animals; Estrus; Female; Genitalia, Female; Hypothalamus; Imipramine; Parasympathetic Nervous System | 1971 |
Clinical psychiatry.
Topics: Abortion, Spontaneous; Bipolar Disorder; Brain; Carbonates; Drug Therapy, Combination; Electric Stim | 1971 |
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau | 1969 |
Use of antidepressant drugs during the first trimester.
Topics: Amitriptyline; Desipramine; Embryo, Mammalian; Female; Gestational Age; Humans; Imipramine; Nortript | 1969 |
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc | 1969 |
The effect of pilocarpine in combination with monoamine oxidase inhibitors, imipramine or desmethylimipramine on oestrous behaviour in female rats.
Topics: Amines; Animals; Body Temperature; Castration; Central Nervous System; Desipramine; Drug Synergism; | 1970 |
Placental transfer of desmethylimipramine.
Topics: Animals; Desipramine; Female; Fetus; Fluorometry; Imipramine; Injections, Intramuscular; Maternal-Fe | 1968 |
Drug defaulting in a general practice.
Topics: Anti-Bacterial Agents; Drug Therapy; Drug Utilization; Family Practice; Female; Fluorescence; Humans | 1969 |
A new antidepressant: desipramine hydrochloride (Norpramin, Pertofrane).
Topics: Adolescent; Aged; Animals; Child; Desipramine; Female; Humans; Imipramine; Pregnancy | 1965 |
[Use of psychopharmacologic drugs in gynecology and obstetrics].
Topics: Amitriptyline; Chlordiazepoxide; Diazepam; Female; Genital Diseases, Female; Humans; Hypnotics and S | 1966 |
[Action of tofranil on the human embryo].
Topics: Adult; Depression; Female; Fetus; Humans; Imipramine; Infant, Newborn; Pregnancy; Pregnancy Complica | 1966 |