Page last updated: 2024-10-29

imipramine and Pheochromocytoma

imipramine has been researched along with Pheochromocytoma in 8 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
" The case of a 35-year-old man with an occult pheochromocytoma presenting with hypotension and cardiogenic shock shortly after beginning imipramine therapy is presented."8.79Imipramine-provoked paradoxical pheochromocytoma crisis: a case of cardiogenic shock. ( Ferguson, KL, 1994)
"A pheochromocytoma was diagnosed in a 14-year-old boy developing hypertension after treatment with imipramine for primary nocturnal enuresis."7.67Pheochromocytoma diagnosed in an enuretic boy after imipramine-induced hypertension. ( Birkebaek, NH; Perrild, BD, 1986)
" The case of a 35-year-old man with an occult pheochromocytoma presenting with hypotension and cardiogenic shock shortly after beginning imipramine therapy is presented."4.79Imipramine-provoked paradoxical pheochromocytoma crisis: a case of cardiogenic shock. ( Ferguson, KL, 1994)
"We have examined how fentanyl modulates [3H]noradrenaline uptake in two cultured neuronal cell preparations, the human neuroblastoma SH-SY5Y and the rat phaeochromocytoma PC12."3.68Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells. ( Atcheson, R; Lambert, DG; Rowbotham, DJ, 1993)
"A pheochromocytoma was diagnosed in a 14-year-old boy developing hypertension after treatment with imipramine for primary nocturnal enuresis."3.67Pheochromocytoma diagnosed in an enuretic boy after imipramine-induced hypertension. ( Birkebaek, NH; Perrild, BD, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, K1
Ratner, M1
Stoll, M1
Feldman, JM1
Frankel, N1
Coleman, RE1
Ferguson, KL1
Atcheson, R1
Rowbotham, DJ1
Lambert, DG1
Mok, J1
Swann, I1
Johnson, ER1
Jones, MD1
Stewart, JN1
Birkebaek, NH1
Perrild, BD1
Kaufmann, JS1

Reviews

1 review available for imipramine and Pheochromocytoma

ArticleYear
Imipramine-provoked paradoxical pheochromocytoma crisis: a case of cardiogenic shock.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Cardiomyopathy, Dilated; Diagnosis, Differential; Emergency Service,

1994

Other Studies

7 other studies available for imipramine and Pheochromocytoma

ArticleYear
Pheochromocytoma unmasked by imipramine in an 8-year-old girl.
    Pediatric emergency care, 2003, Volume: 19, Issue:3

    Topics: Catecholamines; Child; Emergencies; Enuresis; Female; Heart Murmurs; Humans; Hypertension; Hypertrop

2003
Platelet uptake of the pheochromocytoma-scanning agent 131I-meta-iodobenzylguanadine.
    Metabolism: clinical and experimental, 1984, Volume: 33, Issue:5

    Topics: 3-Iodobenzylguanidine; Adult; Blood Platelets; Female; Humans; Imipramine; In Vitro Techniques; Iodo

1984
Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Dose-Response Relationship, Drug; Fentanyl; Humans; Imipramine; Mo

1993
Diagnosis of phaeochromocytoma after ingestion of imipramine.
    Archives of disease in childhood, 1978, Volume: 53, Issue:8

    Topics: Adrenal Gland Neoplasms; Child; Diseases in Twins; Enuresis; Female; Humans; Imipramine; Pheochromoc

1978
Occurrence of a pheochromocytoma after ingestion of imipramine.
    The Journal of the American Osteopathic Association, 1979, Volume: 78, Issue:5

    Topics: Abdominal Neoplasms; Adult; Humans; Hypertension; Imipramine; Male; Neoplasms, Multiple Primary; Phe

1979
Pheochromocytoma diagnosed in an enuretic boy after imipramine-induced hypertension.
    Pediatric hematology and oncology, 1986, Volume: 3, Issue:3

    Topics: Adolescent; Adrenal Gland Neoplasms; Enuresis; Headache; Humans; Hypertension; Imipramine; Male; Phe

1986
Letter: Pheochromocytoma and tricyclic antidepressants.
    JAMA, 1974, Sep-02, Volume: 229, Issue:10

    Topics: Adrenal Gland Neoplasms; Adult; Blood Vessels; Catecholamines; Depression; Epilepsy, Tonic-Clonic; F

1974