Page last updated: 2024-10-29

imipramine and Peripheral Nerve Diseases

imipramine has been researched along with Peripheral Nerve Diseases in 3 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Research Excerpts

ExcerptRelevanceReference
"Fifty-two cancer patients diagnosed as having neuropathic pain were allocated into four groups: G400-I group took gabapentin 200 mg and imipramine 10 mg every 12 h orally; G400 group took gabapentin 200 mg every 12 h orally; G800 group took gabapentin 400 mg every 12 h orally; I group took imipramine 10 mg every 12 h orally."9.14Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine. ( Arai, YC; Arakawa, M; Hayashi, R; Kinoshita, A; Kobayashi, K; Kondo, M; Matsubara, S; Matsubara, T; Nishida, K; Nishihara, M; Shimo, K; Suetomi, K; Suzuki, C; Tohyama, Y; Ushida, T, 2010)
"Imipramine dose was increased in steps of 25 mg/d every second week, and blood samples were taken at every dose."6.71TDM-based imipramine treatment in neuropathic pain. ( Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH, 2004)
"Fifty-two cancer patients diagnosed as having neuropathic pain were allocated into four groups: G400-I group took gabapentin 200 mg and imipramine 10 mg every 12 h orally; G400 group took gabapentin 200 mg every 12 h orally; G800 group took gabapentin 400 mg every 12 h orally; I group took imipramine 10 mg every 12 h orally."5.14Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine. ( Arai, YC; Arakawa, M; Hayashi, R; Kinoshita, A; Kobayashi, K; Kondo, M; Matsubara, S; Matsubara, T; Nishida, K; Nishihara, M; Shimo, K; Suetomi, K; Suzuki, C; Tohyama, Y; Ushida, T, 2010)
" In the current study, we evaluated the behavioral effects of two standard drugs used clinically for neuropathic pain, the anticonvulsant gabapentin and antidepressant imipramine, in rats at different times after peripheral nerve injury."3.73The effect of antinociceptive drugs tested at different times after nerve injury in rats. ( Borsook, D; Hama, AT, 2005)
"Imipramine dose was increased in steps of 25 mg/d every second week, and blood samples were taken at every dose."2.71TDM-based imipramine treatment in neuropathic pain. ( Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arai, YC1
Matsubara, T1
Shimo, K1
Suetomi, K1
Nishihara, M1
Ushida, T1
Kobayashi, K1
Suzuki, C1
Kinoshita, A1
Kondo, M1
Matsubara, S1
Hayashi, R1
Tohyama, Y1
Nishida, K1
Arakawa, M1
Rasmussen, PV1
Jensen, TS1
Sindrup, SH1
Bach, FW1
Hama, AT1
Borsook, D1

Trials

2 trials available for imipramine and Peripheral Nerve Diseases

ArticleYear
Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine.
    Journal of anesthesia, 2010, Volume: 24, Issue:3

    Topics: Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal;

2010
TDM-based imipramine treatment in neuropathic pain.
    Therapeutic drug monitoring, 2004, Volume: 26, Issue:4

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Desipramine; Dose-Response Relationship, Drug; Drug Monitorin

2004

Other Studies

1 other study available for imipramine and Peripheral Nerve Diseases

ArticleYear
The effect of antinociceptive drugs tested at different times after nerve injury in rats.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:1

    Topics: Amines; Analgesics; Animals; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Dose-Res

2005