imipramine has been researched along with Pain, Chronic in 4 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this randomized, double blinded, placebo controlled cross-over study, patients with chronic low back pain are randomly assigned to imipramine, oxycodone or clobazam versus active placebo." | 5.20 | Linking altered central pain processing and genetic polymorphism to drug efficacy in chronic low back pain. ( Arendt-Nielsen, L; Curatolo, M; Juni, P; Schliessbach, J; Siegenthaler, A; Vuilleumier, PH; Zeilhofer, HU, 2015) |
| "The involvement of serotonin (5-HT) in chronic pain mechanisms is established." | 1.39 | Chronic pain treatment: the influence of tricyclic antidepressants on serotonin release and uptake in mast cells. ( Ferjan, I; Lipnik-Štangelj, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schliessbach, J | 2 |
| Siegenthaler, A | 2 |
| Bütikofer, L | 1 |
| Limacher, A | 1 |
| Juni, P | 2 |
| Vuilleumier, PH | 2 |
| Stamer, U | 1 |
| Arendt-Nielsen, L | 2 |
| Curatolo, M | 2 |
| Ferjan, I | 1 |
| Lipnik-Štangelj, M | 1 |
| Yasuda, S | 1 |
| Yoshida, M | 1 |
| Yamagata, H | 1 |
| Iwanaga, Y | 1 |
| Suenaga, H | 1 |
| Ishikawa, K | 1 |
| Nakano, M | 1 |
| Okuyama, S | 1 |
| Furukawa, Y | 1 |
| Furukawa, S | 1 |
| Ishikawa, T | 1 |
| Zeilhofer, HU | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Linking Altered Central Pain Processing and Genetic Polymorphism to Drug Efficacy in Chronic Low Back Pain[NCT01179828] | Phase 3 | 150 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for imipramine and Pain, Chronic
| Article | Year |
|---|---|
Effect of single-dose imipramine on chronic low-back and experimental pain. A randomized controlled trial.
Topics: Adult; Chronic Pain; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Imipramine; Low Back Pain; M | 2018 |
Linking altered central pain processing and genetic polymorphism to drug efficacy in chronic low back pain.
Topics: Adolescent; Adult; Aged; Analgesics; Benzodiazepines; Chronic Pain; Clinical Protocols; Clobazam; Cr | 2015 |
2 other studies available for imipramine and Pain, Chronic
| Article | Year |
|---|---|
Chronic pain treatment: the influence of tricyclic antidepressants on serotonin release and uptake in mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Cells, Cultured; Chr | 2013 |
Imipramine ameliorates pain-related negative emotion via induction of brain-derived neurotrophic factor.
Topics: 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chronic | 2014 |