imipramine has been researched along with Niemann-Pick Diseases in 6 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Niemann-Pick Diseases: A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, M | 1 |
| Akaboshi, S | 1 |
| Katsumoto, T | 1 |
| Taniguchi, M | 1 |
| Higaki, K | 1 |
| Tai, T | 1 |
| Sakuraba, H | 1 |
| Ohno, K | 1 |
| Lange, Y | 1 |
| Ye, J | 1 |
| Rigney, M | 1 |
| Steck, T | 1 |
| Goodrum, JF | 1 |
| Brown, JC | 1 |
| Fowler, KA | 1 |
| Bouldin, TW | 1 |
| Roff, CF | 1 |
| Goldin, E | 1 |
| Comly, ME | 1 |
| Cooney, A | 1 |
| Brown, A | 1 |
| Vanier, MT | 2 |
| Miller, SP | 1 |
| Brady, RO | 1 |
| Pentchev, PG | 2 |
| Rodriguez-Lafrasse, C | 1 |
| Rousson, R | 1 |
| Bonnet, J | 1 |
| Louisot, P | 1 |
| Albouz, S | 1 |
| Le Saux, F | 1 |
| Wenger, D | 1 |
| Hauw, JJ | 1 |
| Baumann, N | 1 |
1 review available for imipramine and Niemann-Pick Diseases
| Article | Year |
|---|---|
Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport.
Topics: Amines; Androstenes; Animals; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol Esters | 1991 |
5 other studies available for imipramine and Niemann-Pick Diseases
| Article | Year |
|---|---|
Accumulation of cholesterol and GM2 ganglioside in cells cultured in the presence of progesterone: an implication for the basic defect in Niemann-Pick disease type C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Cells, Cultured; Chole | 1998 |
Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles.
Topics: Androstenes; Anticholesteremic Agents; Cell Line; Cell Membrane; Cells, Cultured; Cholesterol; Cultu | 2000 |
Axonal regeneration, but not myelination, is partially dependent on local cholesterol reutilization in regenerating nerve.
Topics: Adrenergic Uptake Inhibitors; Animals; Axons; Bone Marrow Cells; Bone Marrow Transplantation; Choles | 2000 |
Abnormal cholesterol metabolism in imipramine-treated fibroblast cultures. Similarities with Niemann-Pick type C disease.
Topics: Acetates; Cells, Cultured; Cholesterol Esters; Cholesterol, LDL; Down-Regulation; Fibroblasts; Human | 1990 |
Modifications of sphingomyelin and phosphatidylcholine metabolism by tricyclic antidepressants and phenothiazines.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Line; Chlorpromazine; Desipramine; Dose-Response Rel | 1986 |